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Protein

Pyruvate kinase

Gene

CARUB_v10026152mg

Organism
Capsella rubella
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 5 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. Pyruvate kinase (CARUB_v10026251mg), Pyruvate kinase, Pyruvate kinase, Pyruvate kinase (CARUB_v10022991mg), Pyruvate kinase (CARUB_v10026256mg), Pyruvate kinase (CARUB_v10017008mg), Pyruvate kinase (CARUB_v10013284mg), Pyruvate kinase (CARUB_v10015478mg), Pyruvate kinase (CARUB_v10000751mg), Pyruvate kinase (CARUB_v10026152mg), Pyruvate kinase (CARUB_v10007746mg), Pyruvate kinase (CARUB_v10012411mg)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
Biological processGlycolysisUniRule annotation
LigandMagnesiumUniRule annotation

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00188

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
ORF Names:CARUB_v10026152mgImported
OrganismiCapsella rubellaImported
Taxonomic identifieri81985 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeCapsella
Proteomesi
  • UP000029121 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 428PKInterPro annotationAdd BLAST343
Domaini445 – 571PK_CInterPro annotationAdd BLAST127

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KOiK00873

Family and domain databases

CDDicd00288 Pyruvate_Kinase, 1 hit
Gene3Di2.40.33.10, 1 hit
3.40.1380.20, 1 hit
InterProiView protein in InterPro
IPR001697 Pyr_Knase
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
IPR011037 Pyrv_Knase-like_insert_dom_sf
IPR018209 Pyrv_Knase_AS
IPR015793 Pyrv_Knase_brl
IPR015795 Pyrv_Knase_C
IPR036918 Pyrv_Knase_C_sf
IPR015806 Pyrv_Knase_insert_dom_sf
PANTHERiPTHR11817 PTHR11817, 1 hit
PfamiView protein in Pfam
PF00224 PK, 1 hit
PF02887 PK_C, 1 hit
PRINTSiPR01050 PYRUVTKNASE
SUPFAMiSSF50800 SSF50800, 1 hit
SSF51621 SSF51621, 2 hits
SSF52935 SSF52935, 1 hit
TIGRFAMsiTIGR01064 pyruv_kin, 1 hit
PROSITEiView protein in PROSITE
PS00110 PYRUVATE_KINASE, 1 hit

Sequencei

Sequence statusi: Fragment.

R0GLE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FFFTSKSQKK RRETLHLFIN LSLLSFLRFS LCNFPCSPSQ ISLHKSLFIS
60 70 80 90 100
LSPLTIRDPC FCVLFFCLFL HSLYLAMSMM IEQRPKTKIV CTLGPASRSV
110 120 130 140 150
PMVEKLLRAG MNVARFNFSH GSHEYHQETL DNLRQAMLNT GILCAVMLDT
160 170 180 190 200
KGPEIRTGFL KDGKPIQLKQ GQEITISTDY DLKGDENTIC MSYKKLAVDV
210 220 230 240 250
NPGMVILCAD GTISLLVLSC DRENGTVRCR CENSAMLGER KNVNLPGVVV
260 270 280 290 300
DLPTLTEKDK EDIMQWGVPN QIDMIALSFV RKGSDLVQVR KLLGKHAKTI
310 320 330 340 350
LLMSKVENQE GVANFDDILV NSDAFMIARG DLGMEIPIEK IFLAQKVMIY
360 370 380 390 400
KCNIQGKPVV TATQMLESMI KSPRPTRAEA TDVANAVLDG TDCVMLSGET
410 420 430 440 450
AAGAYPELAV RTMAKICVEA ESTLDYGDVF KRIMQYSPVP MSPLESLASS
460 470 480 490 500
AVRTANSARA TLIMVLTRGG STARLVAKYR PGMPILSVVV PEIKTDFFDW
510 520 530 540 550
SCSDESPARH SLVFRGLIPV LYAGSARASH DESTEEAIEF ATQYGKEKEL
560 570
CKTGDSVVAL LRVGNASVIK ILTVK
Length:575
Mass (Da):63,486
Last modified:June 26, 2013 - v1
Checksum:i9B0F7B5B9E559447
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB870812 Genomic DNA Translation: EOA13135.1
RefSeqiXP_006280237.1, XM_006280175.1

Genome annotation databases

GeneIDi17875041
KEGGicrb:17875041

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB870812 Genomic DNA Translation: EOA13135.1
RefSeqiXP_006280237.1, XM_006280175.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17875041
KEGGicrb:17875041

Phylogenomic databases

KOiK00873

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00188

Family and domain databases

CDDicd00288 Pyruvate_Kinase, 1 hit
Gene3Di2.40.33.10, 1 hit
3.40.1380.20, 1 hit
InterProiView protein in InterPro
IPR001697 Pyr_Knase
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
IPR011037 Pyrv_Knase-like_insert_dom_sf
IPR018209 Pyrv_Knase_AS
IPR015793 Pyrv_Knase_brl
IPR015795 Pyrv_Knase_C
IPR036918 Pyrv_Knase_C_sf
IPR015806 Pyrv_Knase_insert_dom_sf
PANTHERiPTHR11817 PTHR11817, 1 hit
PfamiView protein in Pfam
PF00224 PK, 1 hit
PF02887 PK_C, 1 hit
PRINTSiPR01050 PYRUVTKNASE
SUPFAMiSSF50800 SSF50800, 1 hit
SSF51621 SSF51621, 2 hits
SSF52935 SSF52935, 1 hit
TIGRFAMsiTIGR01064 pyruv_kin, 1 hit
PROSITEiView protein in PROSITE
PS00110 PYRUVATE_KINASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiR0GLE6_9BRAS
AccessioniPrimary (citable) accession number: R0GLE6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: June 20, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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