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UniProtKB - Q9ZW21 (P2C24_ARATH)

Entry version 135 (10 Feb 2021)
Sequence version 1 (01 May 1999)
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Protein

Probable protein phosphatase 2C 24

Gene

At2g29380

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi117Manganese 1By similarity1
Metal bindingi117Manganese 2By similarity1
Metal bindingi118Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi295Manganese 2By similarity1
Metal bindingi351Manganese 2By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable protein phosphatase 2C 24 (EC:3.1.3.16)
Short name:
AtPP2C24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At2g29380
ORF Names:F16P2.24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT2G29380

The Arabidopsis Information Resource

More...TAIRi		locus:2043142, AT2G29380

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003679531 – 362Probable protein phosphatase 2C 24Add BLAST362

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9ZW21

PRoteomics IDEntifications database

More...PRIDEi		Q9ZW21

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		248707

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9ZW21, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9ZW21, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		2837, 15 interactors

Database of interacting proteins

More...DIPi		DIP-48991N

Protein interaction database and analysis system

More...IntActi		Q9ZW21, 18 interactors

STRING: functional protein association networks

More...STRINGi		3702.AT2G29380.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9ZW21

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini77 – 360PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST284

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0698, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_013173_20_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9ZW21

Identification of Orthologs from Complete Genome Data

More...OMAi		VENCASY

Database of Orthologous Groups

More...OrthoDBi		1044139at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9ZW21

Family and domain databases

Conserved Domains Database

More...CDDi		cd00143, PP2Cc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000222, PP2C_BS
IPR036457, PPM-type_dom_sf
IPR001932, PPM-type_phosphatase_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00481, PP2C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00332, PP2Cc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF81606, SSF81606, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01032, PPM_1, 1 hit
PS51746, PPM_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ZW21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEICYEVVT DACPSSVYES TPAHSRRRPR FQTVMHEDWE KNCKRSKQEA 
        60         70         80         90        100
LATRYSSIPR SSREDFSDQN VDVSSPRYGV SSVCGRRREM EDAVAIHPSF 
       110        120        130        140        150
SSPKNSEFPQ HYFGVYDGHG CSHVAARCRE RLHKLVQEEL SSDMEDEEEW 
       160        170        180        190        200
KTTMERSFTR MDKEVVSWGD SVVTANCKCD LQTPACDSVG STAVVSVITP 
       210        220        230        240        250
DKIVVANCGD SRAVLCRNGK PVPLSTDHKP DRPDELDRIE GAGGRVIYWD 
       260        270        280        290        300
CPRVLGVLAM SRAIGDNYLK PYVSCEPEVT ITDRRDDDCL ILASDGLWDV 
       310        320        330        340        350
VSNETACSVA RMCLRGGGRR QDNEDPAISD KACTEASVLL TKLALARNSS 
       360 
DNVSVVVIDL RR
Length:362
Mass (Da):40,297
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD127B5057DA3E0D4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC004561 Genomic DNA Translation: AAC95200.1
CP002685 Genomic DNA Translation: AEC08244.1
DQ056553 mRNA Translation: AAY78704.1
BT022047 mRNA Translation: AAY25459.1
BT023483 mRNA Translation: AAY57322.1

Protein sequence database of the Protein Information Resource

More...PIRi		F84695

NCBI Reference Sequences

More...RefSeqi		NP_180499.1, NM_128492.3

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT2G29380.1; AT2G29380.1; AT2G29380

Database of genes from NCBI RefSeq genomes

More...GeneIDi		817487

Gramene; a comparative resource for plants

More...Gramenei		AT2G29380.1; AT2G29380.1; AT2G29380

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT2G29380

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004561 Genomic DNA Translation: AAC95200.1
CP002685 Genomic DNA Translation: AEC08244.1
DQ056553 mRNA Translation: AAY78704.1
BT022047 mRNA Translation: AAY25459.1
BT023483 mRNA Translation: AAY57322.1
PIRiF84695
RefSeqiNP_180499.1, NM_128492.3

3D structure databases

SMRiQ9ZW21
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi2837, 15 interactors
DIPiDIP-48991N
IntActiQ9ZW21, 18 interactors
STRINGi3702.AT2G29380.1

Proteomic databases

PaxDbiQ9ZW21
PRIDEiQ9ZW21
ProteomicsDBi248707

Genome annotation databases

EnsemblPlantsiAT2G29380.1; AT2G29380.1; AT2G29380
GeneIDi817487
GrameneiAT2G29380.1; AT2G29380.1; AT2G29380
KEGGiath:AT2G29380

Organism-specific databases

AraportiAT2G29380
TAIRilocus:2043142, AT2G29380

Phylogenomic databases

eggNOGiKOG0698, Eukaryota
HOGENOMiCLU_013173_20_0_1
InParanoidiQ9ZW21
OMAiVENCASY
OrthoDBi1044139at2759
PhylomeDBiQ9ZW21

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9ZW21

Gene expression databases

ExpressionAtlasiQ9ZW21, baseline and differential
GenevisibleiQ9ZW21, AT

Family and domain databases

CDDicd00143, PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR000222, PP2C_BS
IPR036457, PPM-type_dom_sf
IPR001932, PPM-type_phosphatase_dom
PfamiView protein in Pfam
PF00481, PP2C, 1 hit
SMARTiView protein in SMART
SM00332, PP2Cc, 1 hit
SUPFAMiSSF81606, SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032, PPM_1, 1 hit
PS51746, PPM_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP2C24_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ZW21
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 1999
Last modified: February 10, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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