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UniProtKB - Q9ZW11 (LRK32_ARATH)
Protein
Putative inactive L-type lectin-domain containing receptor kinase III.2
Gene
LECRK32
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici.
1 PublicationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 380 | ATPPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 358 – 366 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- carbohydrate binding Source: UniProtKB-KW
- transmembrane receptor protein serine/threonine kinase activity Source: GO_Central
GO - Biological processi
- defense response to bacterium Source: GO_Central
- defense response to oomycetes Source: UniProtKB
Keywordsi
Molecular function | Receptor |
Biological process | Plant defense |
Ligand | ATP-binding, Lectin, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Putative inactive L-type lectin-domain containing receptor kinase III.21 PublicationShort name: LecRK-III.21 Publication |
Gene namesi | Name:LECRK321 Publication Ordered Locus Names:At2g29250Imported ORF Names:F16P2.37Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G29250 |
TAIRi | locus:2043127, AT2G29250 |
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Single-pass type I membrane protein Sequence analysis
Plasma Membrane
- plasma membrane Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 24 – 303 | ExtracellularSequence analysisAdd BLAST | 280 | |
Transmembranei | 304 – 324 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 325 – 623 | CytoplasmicSequence analysisAdd BLAST | 299 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Increased susceptibility to the oomycetes Phytophthora brassicae and Phytophthora capsici.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_0000403084 | 24 – 623 | Putative inactive L-type lectin-domain containing receptor kinase III.2Add BLAST | 600 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 57 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 78 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 127 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 184 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 202 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 209 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 230 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 298 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q9ZW11 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 2824, 30 interactors |
IntActi | Q9ZW11, 29 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 352 – 616 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 265 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 26 – 262 | Legume-lectin likeAdd BLAST | 237 |
Domaini
The protein kinase domain is predicted to be catalytically inactive.Curated
Sequence similaritiesi
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QSJ4, Eukaryota |
HOGENOMi | CLU_000288_62_3_1 |
InParanoidi | Q9ZW11 |
OMAi | RRCDKRI |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q9ZW11 |
Family and domain databases
CDDi | cd06899, lectin_legume_LecRK_Arcelin_ConA, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR011009, Kinase-like_dom_sf IPR001220, Legume_lectin_dom IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom |
Pfami | View protein in Pfam PF00139, Lectin_legB, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00307, LECTIN_LEGUME_BETA, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9ZW11-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANTYKSIAV SIIFLLYFSC VSSQQQTKFL NHGFLEANLL KSGSSKIHPS
60 70 80 90 100
GHLELTNTSM RQIGQAFHGF PIPFLNPNSS NLVSFPTSFV FAITPGPGAP
110 120 130 140 150
GHGLAFVISP SLDFSGALPS NYLGLFNTSN NGNSLNCILA VEFDTVQAVE
160 170 180 190 200
LNDIDDNHVG IDLNGVISIE STSAEYFDDR EAKNISLRLA SGKPIRVWIE
210 220 230 240 250
YNATETMLNV TLAPLDRPKP KLPLLSRKLN LSGIISEENY VGFSAATGTV
260 270 280 290 300
TSSHFVLGWS FSIEGKASDF DITKLPSLPD PLPPLSPSPS PPVSVMKNSS
310 320 330 340 350
NTMLIIIIAA SAIFGILILS FLAVCFFRRT ENFTGGARKF SHQTISSATG
360 370 380 390 400
GFDNSKLLGE GNSGSFYKGQ LAPTEIIAVK RITCNTRQEK TALIAEIDAI
410 420 430 440 450
SKVKQRNLVD LHGYCSKGNE IYLVYEYVIN RSLDRFLFSN DLPVLKWVHR
460 470 480 490 500
FCIIKGIASA LQHLHAEVQK PLIHGNVKAS NVLLDGELNA RLGDYGHGSR
510 520 530 540 550
HSTTGHVAPE LVNTGKATCA TDVFEFGVLI MEIVCGRRAI EPTKEPVEIS
560 570 580 590 600
LVNWVLRGVK SGNLLRRCDK RIKKKNLVSE EVLLVLKTGL LCVRRSPEDR
610 620
PMMKKVLEYL NGTEHLPHDD YVV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004561 Genomic DNA Translation: AAC95210.1 CP002685 Genomic DNA Translation: AEC08225.1 |
PIRi | C84694 |
RefSeqi | NP_180488.1, NM_128481.1 |
Genome annotation databases
EnsemblPlantsi | AT2G29250.1; AT2G29250.1; AT2G29250 |
GeneIDi | 817474 |
Gramenei | AT2G29250.1; AT2G29250.1; AT2G29250 |
KEGGi | ath:AT2G29250 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004561 Genomic DNA Translation: AAC95210.1 CP002685 Genomic DNA Translation: AEC08225.1 |
PIRi | C84694 |
RefSeqi | NP_180488.1, NM_128481.1 |
3D structure databases
AlphaFoldDBi | Q9ZW11 |
SMRi | Q9ZW11 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 2824, 30 interactors |
IntActi | Q9ZW11, 29 interactors |
Proteomic databases
PaxDbi | Q9ZW11 |
Genome annotation databases
EnsemblPlantsi | AT2G29250.1; AT2G29250.1; AT2G29250 |
GeneIDi | 817474 |
Gramenei | AT2G29250.1; AT2G29250.1; AT2G29250 |
KEGGi | ath:AT2G29250 |
Organism-specific databases
Araporti | AT2G29250 |
TAIRi | locus:2043127, AT2G29250 |
Phylogenomic databases
eggNOGi | ENOG502QSJ4, Eukaryota |
HOGENOMi | CLU_000288_62_3_1 |
InParanoidi | Q9ZW11 |
OMAi | RRCDKRI |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q9ZW11 |
Miscellaneous databases
PROi | PR:Q9ZW11 |
Gene expression databases
ExpressionAtlasi | Q9ZW11, differential |
Genevisiblei | Q9ZW11, AT |
Family and domain databases
CDDi | cd06899, lectin_legume_LecRK_Arcelin_ConA, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR011009, Kinase-like_dom_sf IPR001220, Legume_lectin_dom IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom |
Pfami | View protein in Pfam PF00139, Lectin_legB, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00307, LECTIN_LEGUME_BETA, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | LRK32_ARATH | |
Accessioni | Q9ZW11Primary (citable) accession number: Q9ZW11 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2011 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families