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UniProtKB - Q9ZVM9 (Y1461_ARATH)
Protein
Probable serine/threonine-protein kinase At1g54610
Gene
At1g54610
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 147 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 242 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 124 – 132 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
- protein serine/threonine/tyrosine kinase activity Source: RHEA
- protein serine kinase activity Source: RHEA
- RNA polymerase II CTD heptapeptide repeat kinase activity Source: GO_Central
GO - Biological processi
- phosphorylation of RNA polymerase II C-terminal domain Source: GO_Central
- positive regulation of transcription elongation from RNA polymerase II promoter Source: GO_Central
- protein phosphorylation Source: GO_Central
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At1g54610 ORF Names:T22H22.5 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G54610 |
TAIRi | locus:2199491, AT1G54610 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Other locations
- cyclin-dependent protein kinase holoenzyme complex Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000305183 | 1 – 572 | Probable serine/threonine-protein kinase At1g54610Add BLAST | 572 |
Proteomic databases
PaxDbi | Q9ZVM9 |
PRIDEi | Q9ZVM9 |
ProteomicsDBi | 242389 [Q9ZVM9-1] |
PTM databases
iPTMneti | Q9ZVM9 |
SwissPalmi | Q9ZVM9 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9ZVM9, baseline and differential |
Genevisiblei | Q9ZVM9, AT |
Interactioni
Binary interactionsi
Protein-protein interaction databases
BioGRIDi | 27128, 6 interactors |
IntActi | Q9ZVM9, 8 interactors |
STRINGi | 3702.AT1G54610.2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 118 – 402 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 285 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 89 | DisorderedSequence analysisAdd BLAST | 89 | |
Regioni | 409 – 474 | DisorderedSequence analysisAdd BLAST | 66 | |
Regioni | 526 – 572 | DisorderedSequence analysisAdd BLAST | 47 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 12 – 42 | Polar residuesSequence analysisAdd BLAST | 31 | |
Compositional biasi | 44 – 75 | Basic and acidic residuesSequence analysisAdd BLAST | 32 | |
Compositional biasi | 417 – 458 | Basic and acidic residuesSequence analysisAdd BLAST | 42 | |
Compositional biasi | 526 – 547 | Polar residuesSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0600, Eukaryota |
InParanoidi | Q9ZVM9 |
OMAi | SDPYACE |
PhylomeDBi | Q9ZVM9 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketNote: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q9ZVM9-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGCVFGREAA TTTTAEAKQA KSSKASSGVV VVGESSVTKS NGVIADDVEK
60 70 80 90 100
KKNEEANGDK ERKSSKGDRR RSTKPNPRLS NPSKHWRGEQ VAAGWPSWLS
110 120 130 140 150
DACGEALNGW VPRKADTFEK IDKIGQGTYS NVYKAKDMLT GKIVALKKVR
160 170 180 190 200
FDNLEPESVK FMAREILVLR RLDHPNVVKL EGLVTSRMSC SLYLVFQYMD
210 220 230 240 250
HDLAGLASSP VVKFSESEVK CLMRQLISGL EHCHSRGVLH RDIKGSNLLI
260 270 280 290 300
DDGGVLKIAD FGLATIFDPN HKRPMTSRVV TLWYRAPELL LGATDYGVGI
310 320 330 340 350
DLWSAGCILA ELLAGRPIMP GRTEVEQLHK IYKLCGSPSE DYWKKGKFTH
360 370 380 390 400
GAIYKPREPY KRSIRETFKD FPPSSLPLID ALLSIEPEDR QTASAALKSE
410 420 430 440 450
FFTSEPYACE PADLPKYPPS KEIDAKRRDE ETRRQRAASK AQGDGARKNR
460 470 480 490 500
HRDRSNRALP APEANAELQS NVDRRRLITH ANAKSKSEKF PPPHQDGGAM
510 520 530 540 550
GVPLGASQHI DPTFIPRDMV PSFTSSSFNF SKDEPPTQVQ TWSGPLGHPI
560 570
TGVSRKKKDN TKSSKGKRAV VA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005388 Genomic DNA Translation: AAC64876.1 CP002684 Genomic DNA Translation: AEE33123.1 CP002684 Genomic DNA Translation: AEE33124.2 CP002684 Genomic DNA Translation: AEE33125.1 AF370510 mRNA Translation: AAK43887.1 AY128918 mRNA Translation: AAM91318.1 |
PIRi | B96588 |
RefSeqi | NP_001117490.1, NM_001124018.1 [Q9ZVM9-1] NP_001319227.1, NM_001333657.1 [Q9ZVM9-1] NP_175862.1, NM_104338.7 [Q9ZVM9-1] |
Genome annotation databases
EnsemblPlantsi | AT1G54610.1; AT1G54610.1; AT1G54610 [Q9ZVM9-1] AT1G54610.2; AT1G54610.2; AT1G54610 [Q9ZVM9-1] AT1G54610.3; AT1G54610.3; AT1G54610 [Q9ZVM9-1] |
GeneIDi | 841903 |
Gramenei | AT1G54610.1; AT1G54610.1; AT1G54610 [Q9ZVM9-1] AT1G54610.2; AT1G54610.2; AT1G54610 [Q9ZVM9-1] AT1G54610.3; AT1G54610.3; AT1G54610 [Q9ZVM9-1] |
KEGGi | ath:AT1G54610 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005388 Genomic DNA Translation: AAC64876.1 CP002684 Genomic DNA Translation: AEE33123.1 CP002684 Genomic DNA Translation: AEE33124.2 CP002684 Genomic DNA Translation: AEE33125.1 AF370510 mRNA Translation: AAK43887.1 AY128918 mRNA Translation: AAM91318.1 |
PIRi | B96588 |
RefSeqi | NP_001117490.1, NM_001124018.1 [Q9ZVM9-1] NP_001319227.1, NM_001333657.1 [Q9ZVM9-1] NP_175862.1, NM_104338.7 [Q9ZVM9-1] |
3D structure databases
AlphaFoldDBi | Q9ZVM9 |
SMRi | Q9ZVM9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 27128, 6 interactors |
IntActi | Q9ZVM9, 8 interactors |
STRINGi | 3702.AT1G54610.2 |
PTM databases
iPTMneti | Q9ZVM9 |
SwissPalmi | Q9ZVM9 |
Proteomic databases
PaxDbi | Q9ZVM9 |
PRIDEi | Q9ZVM9 |
ProteomicsDBi | 242389 [Q9ZVM9-1] |
Genome annotation databases
EnsemblPlantsi | AT1G54610.1; AT1G54610.1; AT1G54610 [Q9ZVM9-1] AT1G54610.2; AT1G54610.2; AT1G54610 [Q9ZVM9-1] AT1G54610.3; AT1G54610.3; AT1G54610 [Q9ZVM9-1] |
GeneIDi | 841903 |
Gramenei | AT1G54610.1; AT1G54610.1; AT1G54610 [Q9ZVM9-1] AT1G54610.2; AT1G54610.2; AT1G54610 [Q9ZVM9-1] AT1G54610.3; AT1G54610.3; AT1G54610 [Q9ZVM9-1] |
KEGGi | ath:AT1G54610 |
Organism-specific databases
Araporti | AT1G54610 |
TAIRi | locus:2199491, AT1G54610 |
Phylogenomic databases
eggNOGi | KOG0600, Eukaryota |
InParanoidi | Q9ZVM9 |
OMAi | SDPYACE |
PhylomeDBi | Q9ZVM9 |
Miscellaneous databases
PROi | PR:Q9ZVM9 |
Gene expression databases
ExpressionAtlasi | Q9ZVM9, baseline and differential |
Genevisiblei | Q9ZVM9, AT |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y1461_ARATH | |
Accessioni | Q9ZVM9Primary (citable) accession number: Q9ZVM9 Secondary accession number(s): B3H626 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 2, 2007 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 160 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families