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UniProtKB - Q9ZUU9 (AB3G_ARATH)

Entry version 149 (25 May 2022)
Sequence version 2 (31 May 2011)
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Protein

ABC transporter G family member 3

Gene

ABCG3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi151 – 158ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

Transport Classification Database

More...TCDBi		3.A.1.204.19, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ABC transporter G family member 3
Short name:
ABC transporter ABCG.3
Short name:
AtABCG3
Alternative name(s):
White-brown complex homolog protein 3
Short name:
AtWBC3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCG3
Synonyms:WBC3
Ordered Locus Names:At2g28070
ORF Names:F24D13.14
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT2G28070

The Arabidopsis Information Resource

More...TAIRi		locus:2046203, AT2G28070

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei465 – 485HelicalSequence analysisAdd BLAST21
Transmembranei495 – 515HelicalSequence analysisAdd BLAST21
Transmembranei532 – 552HelicalSequence analysisAdd BLAST21
Transmembranei575 – 595HelicalSequence analysisAdd BLAST21
Transmembranei600 – 620HelicalSequence analysisAdd BLAST21
Transmembranei689 – 709HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002406751 – 730ABC transporter G family member 3Add BLAST730

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei93PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9ZUU9

PRoteomics IDEntifications database

More...PRIDEi		Q9ZUU9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		244537

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9ZUU9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9ZUU9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9ZUU9, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		2701, 5 interactors

STRING: functional protein association networks

More...STRINGi		3702.AT2G28070.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9ZUU9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9ZUU9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini114 – 356ABC transporterPROSITE-ProRule annotationAdd BLAST243
Domaini441 – 653ABC transmembrane type-2Add BLAST213

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 100DisorderedSequence analysisAdd BLAST100

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27Polar residuesSequence analysisAdd BLAST27
Compositional biasi70 – 91Polar residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0061, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000604_57_7_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9ZUU9

Identification of Orthologs from Complete Genome Data

More...OMAi		FKCNRDT

Database of Orthologous Groups

More...OrthoDBi		806939at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.300, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR003439, ABC_transporter-like_ATP-bd
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01061, ABC2_membrane, 1 hit
PF00005, ABC_tran, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382, AAA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50893, ABC_TRANSPORTER_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ZUU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEIQSQSDL YRSSSSSASS PTSRVPSSHF FYVRKPGSLR QPISFEDSPE 
        60         70         80         90        100
WEDTPDVDLR MEDEAGGGDS INDATTTPVS PSLSKMNSGS MASPPVPEGG 
       110        120        130        140        150
AGTGVVRKIA GASIAWKDLT VTMKGKRKYS DKVVKSSNGY AFPGTMTVIM 
       160        170        180        190        200
GPAKSGKSTL LRALAGRLPP SAKMYGEVFV NGSKSHMPYG SYGFVERETQ 
       210        220        230        240        250
LIGSLTVREF LYYSALLQLP GFLFQKRSVV EDAIQAMSLS DYANKLIGGH 
       260        270        280        290        300
CYMKGLRSGE RRRVSIAREL VMRPHILFID EPLYHLDSVS ALLMMVTLKK 
       310        320        330        340        350
LASMGCTLVF TIYQSSTEVF GLFDRICLLS NGNTLFFGET LACLQHFSNA 
       360        370        380        390        400
GFPCPIMQSP SDHFLRAINT DFDRIIAMCK NWQDDNGDFS AVNMDTAVAI 
       410        420        430        440        450
RTLEATYKSS ADADSVEAMI IKLTEREGTQ LKSKGKAGAA TRVAVLTWRS 
       460        470        480        490        500
LLVMSREWKY YWLRLILYMI LTLSIGTLYS GLGHSLSSVA TRVAAVFVFV 
       510        520        530        540        550
SFASLLGIAG IPSLLKEIKI YRSEASNQHS GAFVFLLGQF LGSIPFLFLM 
       560        570        580        590        600
SISSSLVFYF MVGLRDDFSL LMYFVLNFFM CLLVNEGLML FIACIWRDVY 
       610        620        630        640        650
WSTLTLISVH VIMMLAAGHF RIRTALPKPV WTYPFAYISF HTYSIEGLLE 
       660        670        680        690        700
NEYLGEVFAV GEVRSISGYQ AIQGNYQISP DTNAKWRNML VLLAMAFGYR 
       710        720        730
LLVYVLLRFG LNKNVSGRLL LSHKKNNSSR
Length:730
Mass (Da):81,039
Last modified:May 31, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB99996BA8011A79D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC98459 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAM15328 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC005851 Genomic DNA Translation: AAC98459.1 Sequence problems.
AC006929 Genomic DNA Translation: AAM15328.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC08075.1
CP002685 Genomic DNA Translation: ANM62504.1

Protein sequence database of the Protein Information Resource

More...PIRi		D84680

NCBI Reference Sequences

More...RefSeqi		NP_001318302.1, NM_001336143.1
NP_850111.1, NM_179780.1

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT2G28070.1; AT2G28070.1; AT2G28070
AT2G28070.2; AT2G28070.2; AT2G28070

Database of genes from NCBI RefSeq genomes

More...GeneIDi		817351

Gramene; a comparative resource for plants

More...Gramenei		AT2G28070.1; AT2G28070.1; AT2G28070
AT2G28070.2; AT2G28070.2; AT2G28070

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT2G28070

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005851 Genomic DNA Translation: AAC98459.1 Sequence problems.
AC006929 Genomic DNA Translation: AAM15328.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC08075.1
CP002685 Genomic DNA Translation: ANM62504.1
PIRiD84680
RefSeqiNP_001318302.1, NM_001336143.1
NP_850111.1, NM_179780.1

3D structure databases

AlphaFoldDBiQ9ZUU9
SMRiQ9ZUU9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi2701, 5 interactors
STRINGi3702.AT2G28070.1

Protein family/group databases

TCDBi3.A.1.204.19, the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiQ9ZUU9

Proteomic databases

PaxDbiQ9ZUU9
PRIDEiQ9ZUU9
ProteomicsDBi244537

Genome annotation databases

EnsemblPlantsiAT2G28070.1; AT2G28070.1; AT2G28070
AT2G28070.2; AT2G28070.2; AT2G28070
GeneIDi817351
GrameneiAT2G28070.1; AT2G28070.1; AT2G28070
AT2G28070.2; AT2G28070.2; AT2G28070
KEGGiath:AT2G28070

Organism-specific databases

AraportiAT2G28070
TAIRilocus:2046203, AT2G28070

Phylogenomic databases

eggNOGiKOG0061, Eukaryota
HOGENOMiCLU_000604_57_7_1
InParanoidiQ9ZUU9
OMAiFKCNRDT
OrthoDBi806939at2759

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9ZUU9

Gene expression databases

ExpressionAtlasiQ9ZUU9, baseline and differential
GenevisibleiQ9ZUU9, AT

Family and domain databases

Gene3Di3.40.50.300, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR003439, ABC_transporter-like_ATP-bd
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF01061, ABC2_membrane, 1 hit
PF00005, ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50893, ABC_TRANSPORTER_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAB3G_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ZUU9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 31, 2011
Last modified: May 25, 2022
This is version 149 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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