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Entry version 117 (08 May 2019)
Sequence version 1 (01 May 1999)
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Protein

Transcription termination factor MTERF4, chloroplastic

Gene

MTERF4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription termination factor required for processing and steady-state levels of plastid transcripts. Required for splicing of the chloroplastic Clp protease (ClpP) group IIa intron. Required for maturation of 16S rRNA and 23S rRNA in the chloroplast. Essential for embryogenesis (PubMed:21464319). Required for the maintenance of the correct levels of transcripts in the mitochondria and chloroplasts.1 Publication

Miscellaneous

"BELAYA SMERT'" means white death in Russian.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation, Transcription termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription termination factor MTERF4, chloroplasticCurated
Alternative name(s):
Mitochondrial transcription termination factor 41 Publication
Protein BELAYA SMERT'1 Publication
Protein RUGOSA21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTERF41 Publication
Synonyms:BSM1 Publication, RUG21 Publication, TERF31 Publication
Ordered Locus Names:At4g02990Imported
ORF Names:T4I9.13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G02990

The Arabidopsis Information Resource

More...
TAIRi
locus:2139394 AT4G02990

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Mitochondrion, Plastid

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Embryonic lethality when homozygous, due to growth arrest at the late globular stage.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi420P → L in rug2-1; variegated leaves, reduced growth and altered development of chloroplasts and mitochondria. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 45ChloroplastSequence analysisAdd BLAST45
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000043619746 – 541Transcription termination factor MTERF4, chloroplasticAdd BLAST496

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ZT96

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ZT96

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9ZT96 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9ZT96, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G02990.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ZT96

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi65 – 84Ser-richPROSITE-ProRule annotationAdd BLAST20
Compositional biasi520 – 539Glu-richPROSITE-ProRule annotationAdd BLAST20

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the mTERF family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1267 Eukaryota
ENOG410XT49 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000241428

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ZT96

KEGG Orthology (KO)

More...
KOi
K15032

Identification of Orthologs from Complete Genome Data

More...
OMAi
TIDMEEM

Database of Orthologous Groups

More...
OrthoDBi
523198at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ZT96

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.70.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003690 MTERF
IPR038538 MTERF_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02536 mTERF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00733 Mterf, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ZT96-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIRFCNGFT KPGFLLVHFE PPSFFAVRSR SLSDSTYGNL CNHKKRPGTG
60 70 80 90 100
IGLTVQCAIA NRRFSSRSLD SPRRERSSRS SSSSGRDRDR DKDKGRDSKS
110 120 130 140 150
LYSRPSLLDM NKEKAANRAK VYEFLRGIGI VPDELDGLEL PVTADVMKER
160 170 180 190 200
VEFLHKLGLT IEDINNYPLV LGCSVKKNMV PVLDYLGKLG VRKSTFTEFL
210 220 230 240 250
RRYPQVLHSS VVIDLAPVVK YLQGLDIKPS DVPRVLERYP EVLGFKLEGT
260 270 280 290 300
MSTSVAYLVG IGVARREIGG ILTRYPEILG MRVARIIKPL VEYLEVLGIP
310 320 330 340 350
RLAAARLIEK RPHILGFELD DTVKPNVQIL QDFNVRETSL PSIIAQYPEI
360 370 380 390 400
IGIDLKPKLD TQRKLLCSAI HLNPEDLGSL IERMPQFVSL SESPMLKHID
410 420 430 440 450
FLTKCGFSID QTREMVIGCP QVLALNLGIM KLSFEYFQKE MKRPLQDLVD
460 470 480 490 500
FPAFFTYGLE STVKPRHKKI IKKGIKCSLA WMLNCSDEKF EQRMSYDTID
510 520 530 540
IEEVETDPSS FDMNTLMQPE REEESDSEYE EEEDDDDEEF A
Length:541
Mass (Da):61,549
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44BF67C4BA3B8804
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK55704 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BX827924 differs from that shown. Sequencing errors.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF069442 Genomic DNA Translation: AAC79107.1
AL161495 Genomic DNA Translation: CAB77784.1
CP002687 Genomic DNA Translation: AEE82257.1
CP002687 Genomic DNA Translation: ANM67864.1
BX827924 mRNA No translation available.
AF378901 mRNA Translation: AAK55704.1 Different initiation.
AY052742 mRNA Translation: AAK96456.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T01394

NCBI Reference Sequences

More...
RefSeqi
NP_001329662.1, NM_001340410.1
NP_192208.1, NM_116533.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G02990.1; AT4G02990.1; AT4G02990
AT4G02990.2; AT4G02990.2; AT4G02990

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
828116

Gramene; a comparative resource for plants

More...
Gramenei
AT4G02990.1; AT4G02990.1; AT4G02990
AT4G02990.2; AT4G02990.2; AT4G02990

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G02990

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069442 Genomic DNA Translation: AAC79107.1
AL161495 Genomic DNA Translation: CAB77784.1
CP002687 Genomic DNA Translation: AEE82257.1
CP002687 Genomic DNA Translation: ANM67864.1
BX827924 mRNA No translation available.
AF378901 mRNA Translation: AAK55704.1 Different initiation.
AY052742 mRNA Translation: AAK96456.1
PIRiT01394
RefSeqiNP_001329662.1, NM_001340410.1
NP_192208.1, NM_116533.3

3D structure databases

SMRiQ9ZT96
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9ZT96, 2 interactors
STRINGi3702.AT4G02990.1

PTM databases

iPTMnetiQ9ZT96

Proteomic databases

PaxDbiQ9ZT96

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G02990.1; AT4G02990.1; AT4G02990
AT4G02990.2; AT4G02990.2; AT4G02990
GeneIDi828116
GrameneiAT4G02990.1; AT4G02990.1; AT4G02990
AT4G02990.2; AT4G02990.2; AT4G02990
KEGGiath:AT4G02990

Organism-specific databases

AraportiAT4G02990
TAIRilocus:2139394 AT4G02990

Phylogenomic databases

eggNOGiKOG1267 Eukaryota
ENOG410XT49 LUCA
HOGENOMiHOG000241428
InParanoidiQ9ZT96
KOiK15032
OMAiTIDMEEM
OrthoDBi523198at2759
PhylomeDBiQ9ZT96

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9ZT96

Gene expression databases

ExpressionAtlasiQ9ZT96 baseline and differential

Family and domain databases

Gene3Di1.25.70.10, 1 hit
InterProiView protein in InterPro
IPR003690 MTERF
IPR038538 MTERF_sf
PfamiView protein in Pfam
PF02536 mTERF, 1 hit
SMARTiView protein in SMART
SM00733 Mterf, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTEF4_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ZT96
Secondary accession number(s): Q93WJ2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 11, 2016
Last sequence update: May 1, 1999
Last modified: May 8, 2019
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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