UniProtKB - Q9ZSD4 (SY121_ARATH)
Protein
Syntaxin-121
Gene
SYP121
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Vesicle trafficking protein that functions in the secretory pathway.By similarity
GO - Molecular functioni
- protein-membrane adaptor activity Source: TAIR
- SNAP receptor activity Source: GO_Central
- SNARE binding Source: GO_Central
GO - Biological processi
- defense response Source: TAIR
- defense response to fungus Source: TAIR
- exocytosis Source: GO_Central
- intracellular protein transport Source: GO_Central
- maintenance of protein location in plasma membrane Source: TAIR
- negative regulation of defense response Source: TAIR
- protein localization to plasma membrane Source: TAIR
- protein targeting to membrane Source: TAIR
- regulation of stomatal movement Source: TAIR
- response to abscisic acid Source: TAIR
- response to fungus Source: TAIR
- secretion Source: TAIR
- transpiration Source: TAIR
- vesicle docking Source: GO_Central
- vesicle fusion Source: GO_Central
- vesicle-mediated transport Source: TAIR
Keywordsi
Biological process | Protein transport, Transport |
Protein family/group databases
TCDBi | 8.A.91.1.7, the syntaxin (syntaxin) family |
Names & Taxonomyi
Protein namesi | Recommended name: Syntaxin-121Short name: AtSYP121 Alternative name(s): Syntaxin-related protein At-Syr1 |
Gene namesi | Name:SYP121 Synonyms:SYR1 Ordered Locus Names:At3g11820 ORF Names:F26K24.11 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT3G11820 |
TAIRi | locus:2081476, AT3G11820 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Single-pass type IV membrane protein Sequence analysis
Cytosol
- cytosol Source: TAIR
Golgi apparatus
- trans-Golgi network Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- cell plate Source: TAIR
- endomembrane system Source: GO_Central
- integral component of membrane Source: GO_Central
- plasmodesma Source: TAIR
- SNARE complex Source: TAIR
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 285 | CytoplasmicSequence analysisAdd BLAST | 285 | |
Transmembranei | 286 – 306 | Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 307 – 346 | VesicularSequence analysisAdd BLAST | 40 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
ChainiPRO_0000210246 | 1 – 346 | Syntaxin-121Add BLAST | 346 | ||
Isoform 2 (identifier: Q9ZSD4-2) | |||||
Initiator methioninei | RemovedCombined sources |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 | ||
Isoform 2 (identifier: Q9ZSD4-2) | |||||
Modified residuei | 2 | N-acetylalanineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | Q9ZSD4 |
PRIDEi | Q9ZSD4 |
ProteomicsDBi | 226782 [Q9ZSD4-1] |
PTM databases
iPTMneti | Q9ZSD4 |
SwissPalmi | Q9ZSD4 |
Expressioni
Inductioni
Ninefold induction within 30-min exposure to abscisic acid and after 48 hours drought stress.
Gene expression databases
ExpressionAtlasi | Q9ZSD4, baseline and differential |
Genevisiblei | Q9ZSD4, AT |
Interactioni
Subunit structurei
Part of the t-SNARE complex. Binds to SNAP33.
Binary interactionsi
Q9ZSD4
With | #Exp. | IntAct |
---|---|---|
SNAP33 [Q9S7P9] | 4 | EBI-4476863,EBI-603017 |
GO - Molecular functioni
- SNARE binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 5689, 68 interactors |
DIPi | DIP-59829N |
IntActi | Q9ZSD4, 60 interactors |
STRINGi | 3702.AT3G11820.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 214 – 276 | t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST | 63 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 41 – 76 | Sequence analysisAdd BLAST | 36 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 289 – 298 | Poly-Ile | 10 | |
Compositional biasi | 314 – 327 | Gly-richAdd BLAST | 14 |
Sequence similaritiesi
Belongs to the syntaxin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0810, Eukaryota |
InParanoidi | Q9ZSD4 |
PhylomeDBi | Q9ZSD4 |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative initiation. AlignAdd to basketIsoform 1 (identifier: Q9ZSD4-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MNDLFSSSFS RFRSGEPSPR RDVAGGGDGV QMANPAGSTG GVNLDKFFED
60 70 80 90 100
VESVKEELKE LDRLNETLSS CHEQSKTLHN AKAVKDLRSK MDGDVGVALK
110 120 130 140 150
KAKMIKVKLE ALDRANAANR SLPGCGPGSS SDRTRTSVLN GLRKKLMDSM
160 170 180 190 200
DSFNRLRELI SSEYRETVQR RYFTVTGENP DERTLDRLIS TGESERFLQK
210 220 230 240 250
AIQEQGRGRV LDTINEIQER HDAVKDIEKN LRELHQVFLD MAVLVEHQGA
260 270 280 290 300
QLDDIESHVG RASSFIRGGT DQLQTARVYQ KNTRKWTCIA IIILIIIITV
310 320 330 340
VVLAVLKPWN NSSGGGGGGG GGGTTGGSQP NSGTPPNPPQ ARRLLR
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_057947 | 1 – 31 | Missing in isoform 2. CuratedAdd BLAST | 31 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF112864 mRNA Translation: AAD11809.1 AC016795 Genomic DNA Translation: AAF23198.1 CP002686 Genomic DNA Translation: AEE75102.1 CP002686 Genomic DNA Translation: AEE75103.1 AY093151 mRNA Translation: AAM13150.1 BT003393 mRNA Translation: AAO30056.1 AY087842 mRNA Translation: AAM65395.1 |
RefSeqi | NP_187788.1, NM_112015.3 [Q9ZSD4-1] NP_974288.1, NM_202559.3 [Q9ZSD4-2] |
Genome annotation databases
EnsemblPlantsi | AT3G11820.1; AT3G11820.1; AT3G11820 [Q9ZSD4-1] AT3G11820.2; AT3G11820.2; AT3G11820 [Q9ZSD4-2] |
GeneIDi | 820355 |
Gramenei | AT3G11820.1; AT3G11820.1; AT3G11820 [Q9ZSD4-1] AT3G11820.2; AT3G11820.2; AT3G11820 [Q9ZSD4-2] |
KEGGi | ath:AT3G11820 |
Keywords - Coding sequence diversityi
Alternative initiationSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF112864 mRNA Translation: AAD11809.1 AC016795 Genomic DNA Translation: AAF23198.1 CP002686 Genomic DNA Translation: AEE75102.1 CP002686 Genomic DNA Translation: AEE75103.1 AY093151 mRNA Translation: AAM13150.1 BT003393 mRNA Translation: AAO30056.1 AY087842 mRNA Translation: AAM65395.1 |
RefSeqi | NP_187788.1, NM_112015.3 [Q9ZSD4-1] NP_974288.1, NM_202559.3 [Q9ZSD4-2] |
3D structure databases
SMRi | Q9ZSD4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 5689, 68 interactors |
DIPi | DIP-59829N |
IntActi | Q9ZSD4, 60 interactors |
STRINGi | 3702.AT3G11820.1 |
Protein family/group databases
TCDBi | 8.A.91.1.7, the syntaxin (syntaxin) family |
PTM databases
iPTMneti | Q9ZSD4 |
SwissPalmi | Q9ZSD4 |
Proteomic databases
PaxDbi | Q9ZSD4 |
PRIDEi | Q9ZSD4 |
ProteomicsDBi | 226782 [Q9ZSD4-1] |
Genome annotation databases
EnsemblPlantsi | AT3G11820.1; AT3G11820.1; AT3G11820 [Q9ZSD4-1] AT3G11820.2; AT3G11820.2; AT3G11820 [Q9ZSD4-2] |
GeneIDi | 820355 |
Gramenei | AT3G11820.1; AT3G11820.1; AT3G11820 [Q9ZSD4-1] AT3G11820.2; AT3G11820.2; AT3G11820 [Q9ZSD4-2] |
KEGGi | ath:AT3G11820 |
Organism-specific databases
Araporti | AT3G11820 |
TAIRi | locus:2081476, AT3G11820 |
Phylogenomic databases
eggNOGi | KOG0810, Eukaryota |
InParanoidi | Q9ZSD4 |
PhylomeDBi | Q9ZSD4 |
Miscellaneous databases
PROi | PR:Q9ZSD4 |
Gene expression databases
ExpressionAtlasi | Q9ZSD4, baseline and differential |
Genevisiblei | Q9ZSD4, AT |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SY121_ARATH | |
Accessioni | Q9ZSD4Primary (citable) accession number: Q9ZSD4 Secondary accession number(s): F4J7G9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 12, 2003 |
Last sequence update: | May 1, 1999 | |
Last modified: | April 7, 2021 | |
This is version 169 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families