UniProtKB - Q9ZNR6 (PDX12_ARATH)
Protein
Pyridoxal 5'-phosphate synthase-like subunit PDX1.2
Gene
PDX12
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
The protein has no function in the formation of pyridoxal 5'-phosphate.1 Publication
Miscellaneous
Unlike PDX1.1 or PDX1.3, PDX1.2 is unable to interact with PDX2 and restore prototrophy in yeast snz1 mutants.
GO - Molecular functioni
- amine-lyase activity Source: GO_Central
- protein heterodimerization activity Source: TAIR
GO - Biological processi
- cellular amino acid metabolic process Source: GO_Central
- pyridoxal phosphate biosynthetic process Source: GO_Central
- pyridoxine biosynthetic process Source: GO_Central
Keywordsi
Ligand | Pyridoxal phosphate |
Enzyme and pathway databases
BioCyci | ARA:GQT-784-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Pyridoxal 5'-phosphate synthase-like subunit PDX1.2Short name: AtPDX1.2 Short name: AtPDX1;3 |
Gene namesi | Name:PDX12 Synonyms:A37, PDX1L2 Ordered Locus Names:At3g16050 ORF Names:MSL1.3 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT3G16050 |
TAIRi | locus:2093427 AT3G16050 |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000109367 | 2 – 314 | Pyridoxal 5'-phosphate synthase-like subunit PDX1.2Add BLAST | 313 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylalanineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | Q9ZNR6 |
PRIDEi | Q9ZNR6 |
PTM databases
iPTMneti | Q9ZNR6 |
Expressioni
Tissue specificityi
Expressed in callus tissues, flowers and roots. Weakly expressed in leaves and stems.2 Publications
Gene expression databases
ExpressionAtlasi | Q9ZNR6 baseline and differential |
Genevisiblei | Q9ZNR6 AT |
Interactioni
Subunit structurei
Homodimer or heterodimer with PDX1.1 or PDX1.3. No interaction with PDX2.
Binary interactionsi
With | Entry | #Exp. | IntAct | Notes |
---|---|---|---|---|
Q8L940 | 5 | EBI-1545987,EBI-1545956 |
GO - Molecular functioni
- protein heterodimerization activity Source: TAIR
Protein-protein interaction databases
BioGridi | 6184, 5 interactors |
IntActi | Q9ZNR6, 2 interactors |
STRINGi | 3702.AT3G16050.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the PdxS/SNZ family.Curated
Phylogenomic databases
eggNOGi | KOG1606 Eukaryota COG0214 LUCA |
HOGENOMi | HOG000227586 |
KOi | K06215 |
OMAi | NKHNFRA |
OrthoDBi | 1090029at2759 |
PhylomeDBi | Q9ZNR6 |
Family and domain databases
Gene3Di | 3.20.20.70, 1 hit |
InterProi | View protein in InterPro IPR013785 Aldolase_TIM IPR001852 PdxS/SNZ IPR033755 PdxS/SNZ_N IPR011060 RibuloseP-bd_barrel |
PANTHERi | PTHR31829 PTHR31829, 1 hit |
Pfami | View protein in Pfam PF01680 SOR_SNZ, 1 hit |
PIRSFi | PIRSF029271 Pdx1, 1 hit |
SUPFAMi | SSF51366 SSF51366, 1 hit |
PROSITEi | View protein in PROSITE PS01235 PDXS_SNZ_1, 1 hit PS51129 PDXS_SNZ_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9ZNR6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADQAMTDQD QGAVTLYSGT AITDAKKNHP FSVKVGLAQV LRGGAIVEVS
60 70 80 90 100
SVNQAKLAES AGACSVIVSD PVRSRGGVRR MPDPVLIKEV KRAVSVPVMA
110 120 130 140 150
RARVGHFVEA QILESLAVDY IDESEIISVA DDDHFINKHN FRSPFICGCR
160 170 180 190 200
DTGEALRRIR EGAAMIRIQG DLTATGNIAE TVKNVRSLMG EVRVLNNMDD
210 220 230 240 250
DEVFTFAKKI SAPYDLVAQT KQMGRVPVVQ FASGGITTPA DAALMMQLGC
260 270 280 290 300
DGVFVGSEVF DGPDPFKKLR SIVQAVQHYN DPHVLAEMSS GLENAMESLN
310
VRGDRIQDFG QGSV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF029980 mRNA Translation: AAD01897.1 AF029981 Genomic DNA Translation: AAD01898.1 AB012247 Genomic DNA Translation: BAB02670.1 CP002686 Genomic DNA Translation: AEE75766.1 BT003136 mRNA Translation: AAO24568.1 AK228092 mRNA Translation: BAF00051.1 |
RefSeqi | NP_188226.1, NM_112475.3 |
Genome annotation databases
EnsemblPlantsi | AT3G16050.1; AT3G16050.1; AT3G16050 |
GeneIDi | 820850 |
Gramenei | AT3G16050.1; AT3G16050.1; AT3G16050 |
KEGGi | ath:AT3G16050 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF029980 mRNA Translation: AAD01897.1 AF029981 Genomic DNA Translation: AAD01898.1 AB012247 Genomic DNA Translation: BAB02670.1 CP002686 Genomic DNA Translation: AEE75766.1 BT003136 mRNA Translation: AAO24568.1 AK228092 mRNA Translation: BAF00051.1 |
RefSeqi | NP_188226.1, NM_112475.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6HX3 | X-ray | 2.00 | A/C/E/G | 1-314 | [»] | |
6HXG | X-ray | 1.90 | A/C/E/G | 1-314 | [»] | |
6HYE | X-ray | 2.53 | A/C/E/G | 1-314 | [»] | |
SMRi | Q9ZNR6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGridi | 6184, 5 interactors |
IntActi | Q9ZNR6, 2 interactors |
STRINGi | 3702.AT3G16050.1 |
PTM databases
iPTMneti | Q9ZNR6 |
Proteomic databases
PaxDbi | Q9ZNR6 |
PRIDEi | Q9ZNR6 |
Protocols and materials databases
DNASUi | 820850 |
Genome annotation databases
EnsemblPlantsi | AT3G16050.1; AT3G16050.1; AT3G16050 |
GeneIDi | 820850 |
Gramenei | AT3G16050.1; AT3G16050.1; AT3G16050 |
KEGGi | ath:AT3G16050 |
Organism-specific databases
Araporti | AT3G16050 |
TAIRi | locus:2093427 AT3G16050 |
Phylogenomic databases
eggNOGi | KOG1606 Eukaryota COG0214 LUCA |
HOGENOMi | HOG000227586 |
KOi | K06215 |
OMAi | NKHNFRA |
OrthoDBi | 1090029at2759 |
PhylomeDBi | Q9ZNR6 |
Enzyme and pathway databases
BioCyci | ARA:GQT-784-MONOMER |
Miscellaneous databases
PROi | PR:Q9ZNR6 |
Gene expression databases
ExpressionAtlasi | Q9ZNR6 baseline and differential |
Genevisiblei | Q9ZNR6 AT |
Family and domain databases
Gene3Di | 3.20.20.70, 1 hit |
InterProi | View protein in InterPro IPR013785 Aldolase_TIM IPR001852 PdxS/SNZ IPR033755 PdxS/SNZ_N IPR011060 RibuloseP-bd_barrel |
PANTHERi | PTHR31829 PTHR31829, 1 hit |
Pfami | View protein in Pfam PF01680 SOR_SNZ, 1 hit |
PIRSFi | PIRSF029271 Pdx1, 1 hit |
SUPFAMi | SSF51366 SSF51366, 1 hit |
PROSITEi | View protein in PROSITE PS01235 PDXS_SNZ_1, 1 hit PS51129 PDXS_SNZ_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PDX12_ARATH | |
Accessioni | Q9ZNR6Primary (citable) accession number: Q9ZNR6 Secondary accession number(s): Q0WS48 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 15, 2004 |
Last sequence update: | May 1, 1999 | |
Last modified: | September 18, 2019 | |
This is version 137 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references