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UniProtKB - Q9ZNR0 (C78A6_ARATH)
Protein
Cytochrome P450 78A6
Gene
CYP78A6
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Plays role in seed and fruit development. Functions probably in association with CYP78A9 in the regulation of seed growth. Acts maternally to promote seed growth.
1 PublicationMiscellaneous
The gain of function mutants eod3-1D (T-DNA tagging) show increased size of leaves, flowers and seeds, but defects in reproductive development.1 Publication
Cofactori
hemeBy similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 474 | Iron (heme axial ligand)By similarity | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- iron ion binding Source: InterPro
- monooxygenase activity Source: UniProtKB-KW
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
GO - Biological processi
- regulation of growth Source: UniProtKB-KW
- seed development Source: TAIR
Keywordsi
Molecular function | Developmental protein, Monooxygenase, Oxidoreductase |
Biological process | Growth regulation |
Ligand | Heme, Iron, Metal-binding |
Enzyme and pathway databases
BioCyci | ARA:AT2G46660-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CYP78A6 Synonyms:EOD3 Ordered Locus Names:At2g46660 ORF Names:T3A4.4 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G46660 |
TAIRi | locus:2039954, AT2G46660 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 25 – 45 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Disruption phenotypei
Reduced seed size.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000422988 | 1 – 530 | Cytochrome P450 78A6Add BLAST | 530 |
Proteomic databases
PaxDbi | Q9ZNR0 |
Expressioni
Tissue specificityi
Expressed in leaves, sepals, petals, stamens, carpels and developing ovules.1 Publication
Gene expression databases
ExpressionAtlasi | Q9ZNR0, baseline and differential |
Genevisiblei | Q9ZNR0, AT |
Family & Domainsi
Sequence similaritiesi
Belongs to the cytochrome P450 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0156, Eukaryota |
HOGENOMi | CLU_001570_4_0_1 |
InParanoidi | Q9ZNR0 |
OMAi | RYWWNRR |
OrthoDBi | 702827at2759 |
PhylomeDBi | Q9ZNR0 |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9ZNR0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATKLESSLI FALLSKCSVL SQTNLAFSLL AVTIIWLAIS LFLWTYPGGP
60 70 80 90 100
AWGKYLFGRL ISGSYKTGNV IPGPKGFPLV GSMSLMSSTL AHRRIADAAE
110 120 130 140 150
KFGAKRLMAF SLGETRVIVT CNPDVAKEIL NSPVFADRPV KESAYSLMFN
160 170 180 190 200
RAIGFAPHGV YWRTLRRIAS NHLFSTKQIR RAETQRRVIS SQMVEFLEKQ
210 220 230 240 250
SSNEPCFVRE LLKTASLNNM MCSVFGQEYE LEKNHVELRE MVEEGYDLLG
260 270 280 290 300
TLNWTDHLPW LSEFDPQRLR SRCSTLVPKV NRFVSRIISE HRNQTGDLPR
310 320 330 340 350
DFVDVLLSLH GSDKLSDPDI IAVLWEMIFR GTDTVAVLIE WILARMVLHP
360 370 380 390 400
DMQSTVQNEL DQVVGKSRAL DESDLASLPY LTAVVKEVLR LHPPGPLLSW
410 420 430 440 450
ARLAITDTIV DGRLVPAGTT AMVNMWAVSH DPHVWVDPLE FKPERFVAKE
460 470 480 490 500
GEVEFSVLGS DLRLAPFGSG RRICPGKNLG FTTVMFWTAM MLHEFEWGPS
510 520 530
DGNGVDLSEK LRLSCEMANP LPAKLRRRRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005819 Genomic DNA Translation: AAC69923.1 AC006418 Genomic DNA Translation: AAM15240.1 CP002685 Genomic DNA Translation: AEC10736.1 AK226763 mRNA Translation: BAE98862.1 |
PIRi | F84905 |
RefSeqi | NP_182189.1, NM_130231.4 |
Genome annotation databases
EnsemblPlantsi | AT2G46660.1; AT2G46660.1; AT2G46660 |
GeneIDi | 819278 |
Gramenei | AT2G46660.1; AT2G46660.1; AT2G46660 |
KEGGi | ath:AT2G46660 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005819 Genomic DNA Translation: AAC69923.1 AC006418 Genomic DNA Translation: AAM15240.1 CP002685 Genomic DNA Translation: AEC10736.1 AK226763 mRNA Translation: BAE98862.1 |
PIRi | F84905 |
RefSeqi | NP_182189.1, NM_130231.4 |
3D structure databases
AlphaFoldDBi | Q9ZNR0 |
SMRi | Q9ZNR0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT2G46660.1 |
Proteomic databases
PaxDbi | Q9ZNR0 |
Genome annotation databases
EnsemblPlantsi | AT2G46660.1; AT2G46660.1; AT2G46660 |
GeneIDi | 819278 |
Gramenei | AT2G46660.1; AT2G46660.1; AT2G46660 |
KEGGi | ath:AT2G46660 |
Organism-specific databases
Araporti | AT2G46660 |
TAIRi | locus:2039954, AT2G46660 |
Phylogenomic databases
eggNOGi | KOG0156, Eukaryota |
HOGENOMi | CLU_001570_4_0_1 |
InParanoidi | Q9ZNR0 |
OMAi | RYWWNRR |
OrthoDBi | 702827at2759 |
PhylomeDBi | Q9ZNR0 |
Enzyme and pathway databases
BioCyci | ARA:AT2G46660-MONOMER |
Miscellaneous databases
PROi | PR:Q9ZNR0 |
Gene expression databases
ExpressionAtlasi | Q9ZNR0, baseline and differential |
Genevisiblei | Q9ZNR0, AT |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | C78A6_ARATH | |
Accessioni | Q9ZNR0Primary (citable) accession number: Q9ZNR0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2013 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families