Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutaconyl-CoA decarboxylase subunit delta

Gene

gcdD

Organism
Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). Possible membrane anchor for the alpha subunit.

Catalytic activityi

4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO2.

Pathwayi: L-glutamate degradation via hydroxyglutarate pathway

This protein is involved in step 5 of the subpathway that synthesizes crotonoyl-CoA from L-glutamate.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. Glutaconate CoA-transferase subunit B (gctB), Glutaconate CoA-transferase subunit A (gctA)
  4. (R)-2-hydroxyglutaryl-CoA dehydratase, subunit beta (hgdB), (R)-2-hydroxyglutaryl-CoA dehydratase activating ATPase (hgdC), (R)-2-hydroxyglutaryl-CoA dehydratase, subunit alpha (hgdA)
  5. Glutaconyl-CoA decarboxylase subunit delta (gcdD), Glutaconyl-CoA decarboxylase subunit gamma (gcdC), Glutaconyl-CoA decarboxylase subunit alpha (gcdA), Glutaconyl-CoA decarboxylase subunit beta (gcdB)
This subpathway is part of the pathway L-glutamate degradation via hydroxyglutarate pathway, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes crotonoyl-CoA from L-glutamate, the pathway L-glutamate degradation via hydroxyglutarate pathway and in Amino-acid degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
Biological processIon transport, Sodium transport, Transport
LigandSodium

Enzyme and pathway databases

BioCyciAFER591001:G1GH7-1899-MONOMER
MetaCyc:MONOMER-1057
SABIO-RKiQ9ZAA8
UniPathwayi
UPA00533;UER00688

Protein family/group databases

TCDBi3.B.1.1.3 the na(+)-transporting carboxylic acid decarboxylase (nat-dc) family

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaconyl-CoA decarboxylase subunit delta (EC:4.1.1.70)
Gene namesi
Name:gcdD
Ordered Locus Names:Acfer_1836
OrganismiAcidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4)
Taxonomic identifieri591001 [NCBI]
Taxonomic lineageiBacteriaFirmicutesNegativicutesAcidaminococcalesAcidaminococcaceaeAcidaminococcus
Proteomesi
  • UP000001902 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 32HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002164661 – 107Glutaconyl-CoA decarboxylase subunit deltaAdd BLAST107

Interactioni

Subunit structurei

Heterooctamer consisting of two alpha, two beta, two gamma and two delta subunits.

Protein-protein interaction databases

STRINGi591001.Acfer_1836

Structurei

3D structure databases

SMRiQ9ZAA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OadG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000097668
KOiK01615
OMAiIIMLINM

Family and domain databases

InterProiView protein in InterPro
IPR005899 Na_pump_deCOase
PfamiView protein in Pfam
PF04277 OAD_gamma, 1 hit
TIGRFAMsiTIGR01195 oadG_fam, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZAA8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDNPWLIMM INMTIVFGVL IVLGILMVLI HAVDPTKKVQ GKKKPVVAKP
60 70 80 90 100
APSAAASKRQ EEEKVAAMAA VLALVQDEDD MIAAALSAAI AEHKRKMEPM

NLPHHSF
Length:107
Mass (Da):11,624
Last modified:May 1, 1999 - v1
Checksum:i7B363CF48D435C82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030576 Genomic DNA Translation: AAC69171.1
CP001859 Genomic DNA Translation: ADB48190.1
RefSeqiWP_012939173.1, NC_013740.1

Genome annotation databases

EnsemblBacteriaiADB48190; ADB48190; Acfer_1836
KEGGiafn:Acfer_1836

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030576 Genomic DNA Translation: AAC69171.1
CP001859 Genomic DNA Translation: ADB48190.1
RefSeqiWP_012939173.1, NC_013740.1

3D structure databases

SMRiQ9ZAA8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi591001.Acfer_1836

Protein family/group databases

TCDBi3.B.1.1.3 the na(+)-transporting carboxylic acid decarboxylase (nat-dc) family

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB48190; ADB48190; Acfer_1836
KEGGiafn:Acfer_1836

Phylogenomic databases

HOGENOMiHOG000097668
KOiK01615
OMAiIIMLINM

Enzyme and pathway databases

UniPathwayi
UPA00533;UER00688

BioCyciAFER591001:G1GH7-1899-MONOMER
MetaCyc:MONOMER-1057
SABIO-RKiQ9ZAA8

Family and domain databases

InterProiView protein in InterPro
IPR005899 Na_pump_deCOase
PfamiView protein in Pfam
PF04277 OAD_gamma, 1 hit
TIGRFAMsiTIGR01195 oadG_fam, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGCDD_ACIFV
AccessioniPrimary (citable) accession number: Q9ZAA8
Secondary accession number(s): D2RM88
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again