UniProtKB - Q9Z9P6 (REX_BACHD)
Protein
Redox-sensing transcriptional repressor Rex
Gene
rex
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Functioni
Modulates transcription in response to changes in cellular NADH/NAD+ redox state.UniRule annotation
Regions
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| DNA bindingi | 18 – 57 | H-T-H motifUniRule annotationAdd BLAST | 40 | |
| Nucleotide bindingi | 92 – 97 | NADUniRule annotation | 6 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity Source: UniProtKB-UniRule
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: InterPro
- response to redox state Source: InterPro
Keywordsi
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
| Ligand | NAD |
Names & Taxonomyi
| Protein namesi | Recommended name: Redox-sensing transcriptional repressor RexUniRule annotation |
| Gene namesi | Name:rexUniRule annotation Ordered Locus Names:BH0551 |
| Organismi | Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) |
| Taxonomic identifieri | 272558 [NCBI] |
| Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Alkalihalobacillus › |
| Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| ChainiPRO_0000097884 | 1 – 211 | Redox-sensing transcriptional repressor RexAdd BLAST | 211 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
| STRINGi | 272558.10173164 |
Family & Domainsi
Sequence similaritiesi
Belongs to the transcriptional regulatory Rex family.UniRule annotation
Phylogenomic databases
| eggNOGi | COG2344, Bacteria |
| HOGENOMi | CLU_061534_1_1_9 |
| OMAi | HEQRKAG |
| OrthoDBi | 1872374at2 |
Family and domain databases
| Gene3Di | 1.10.10.10, 1 hit |
| HAMAPi | MF_01131, Rex, 1 hit |
| InterProi | View protein in InterPro IPR003781, CoA-bd IPR036291, NAD(P)-bd_dom_sf IPR009718, Rex_DNA-bd_C_dom IPR022876, Tscrpt_rep_Rex IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
| PANTHERi | PTHR35786, PTHR35786, 1 hit |
| Pfami | View protein in Pfam PF02629, CoA_binding, 1 hit PF06971, Put_DNA-bind_N, 1 hit |
| SMARTi | View protein in SMART SM00881, CoA_binding, 1 hit |
| SUPFAMi | SSF46785, SSF46785, 1 hit SSF51735, SSF51735, 1 hit |
Sequencei
Sequence statusi: Complete.
Q9Z9P6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNEPTKIPQ ATAKRLPLYY RFLENLHASG KQRVSSSELS EAVKVDSATI
60 70 80 90 100
RRDFSYFGAL GKKGYGYNVN YLLTFFRKTL HQDELTKVML IGVGNLGTAL
110 120 130 140 150
LNYNFSKNNH TQIVMAFDVD REKIGNTVSG VKIENLDNLE NKITSDVSVA
160 170 180 190 200
ILTVPAAVAQ KTADRLVNAG VKGILNFTPA RIAVPEHVRV HHIDLSVELQ
210
ALIYFLKHYP L
Sequence databases
| Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB013375 Genomic DNA Translation: BAA75386.1 BA000004 Genomic DNA Translation: BAB04270.1 |
| PIRi | G83718 |
| RefSeqi | WP_010896728.1, NC_002570.2 |
Genome annotation databases
| EnsemblBacteriai | BAB04270; BAB04270; BAB04270 |
| KEGGi | bha:BH0551 |
Similar proteinsi
Cross-referencesi
Sequence databases
| Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB013375 Genomic DNA Translation: BAA75386.1 BA000004 Genomic DNA Translation: BAB04270.1 |
| PIRi | G83718 |
| RefSeqi | WP_010896728.1, NC_002570.2 |
3D structure databases
| SMRi | Q9Z9P6 |
| ModBasei | Search... |
Protein-protein interaction databases
| STRINGi | 272558.10173164 |
Genome annotation databases
| EnsemblBacteriai | BAB04270; BAB04270; BAB04270 |
| KEGGi | bha:BH0551 |
Phylogenomic databases
| eggNOGi | COG2344, Bacteria |
| HOGENOMi | CLU_061534_1_1_9 |
| OMAi | HEQRKAG |
| OrthoDBi | 1872374at2 |
Family and domain databases
| Gene3Di | 1.10.10.10, 1 hit |
| HAMAPi | MF_01131, Rex, 1 hit |
| InterProi | View protein in InterPro IPR003781, CoA-bd IPR036291, NAD(P)-bd_dom_sf IPR009718, Rex_DNA-bd_C_dom IPR022876, Tscrpt_rep_Rex IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
| PANTHERi | PTHR35786, PTHR35786, 1 hit |
| Pfami | View protein in Pfam PF02629, CoA_binding, 1 hit PF06971, Put_DNA-bind_N, 1 hit |
| SMARTi | View protein in SMART SM00881, CoA_binding, 1 hit |
| SUPFAMi | SSF46785, SSF46785, 1 hit SSF51735, SSF51735, 1 hit |
| ProtoNeti | Search... |
| MobiDBi | Search... |
Entry informationi
| Entry namei | REX_BACHD | |
| Accessioni | Q9Z9P6Primary (citable) accession number: Q9Z9P6 | |
| Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 16, 2004 |
| Last sequence update: | May 1, 1999 | |
| Last modified: | December 2, 2020 | |
| This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
| Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
| Annotation program | Prokaryotic Protein Annotation Program | |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families




