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UniProtKB - Q9Z7Y6 (CDSA_CHLPN)
Protein
Phosphatidate cytidylyltransferase
Gene
cdsA
Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Functioni
Catalytic activityi
- EC:2.7.7.41
: CDP-diacylglycerol biosynthesis Pathwayi
This protein is involved in step 3 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate. This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.
GO - Molecular functioni
- phosphatidate cytidylyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Nucleotidyltransferase, Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00614 |
Names & Taxonomyi
Protein namesi | Recommended name: Phosphatidate cytidylyltransferase (EC:2.7.7.41)Alternative name(s): CDP-DAG synthase CDP-DG synthase CDP-diacylglycerol synthase Short name: CDS CDP-diglyceride pyrophosphorylase CDP-diglyceride synthase CTP:phosphatidate cytidylyltransferase |
Gene namesi | Name:cdsA Ordered Locus Names:CPn_0567, CP_0182, CpB0589 |
Organismi | Chlamydia pneumoniae (Chlamydophila pneumoniae) |
Taxonomic identifieri | 83558 [NCBI] |
Taxonomic lineagei | Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Multi-pass membrane protein By similarity
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 30 – 50 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 73 – 93 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 100 – 120 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 127 – 147 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 167 – 187 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 205 – 225 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 235 – 255 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 280 – 300 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000090732 | 1 – 308 | Phosphatidate cytidylyltransferaseAdd BLAST | 308 |
Family & Domainsi
Sequence similaritiesi
Belongs to the CDS family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0575, Bacteria |
HOGENOMi | CLU_037294_3_3_0 |
OrthoDBi | 1533756at2 |
i Sequence
Sequence statusi: Complete.
Q9Z7Y6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLNSNKFKSK TGAYGDLFQR VVVHSLVLTF LVLLLYSSLF PLTSFALGFI
60 70 80 90 100
TATCGAVGTY EYSSMAKAKM HYPLSTFSAI GSFLFLALSF LSIRWGHSLP
110 120 130 140 150
GFFDALPWTL LIVWVVWSIF RVRKSTIGAL QLSGVTLFSI LYVGIPIRLF
160 170 180 190 200
LHVLYSFIHT QEPYLGIWWA SFLIATTKGA DIFGYFFGKA FGNKKIAPQI
210 220 230 240 250
SPNKTVVGFV AGCLGATLIS FIFFLQIPTR FASYFPMPAI LIPLGLALGI
260 270 280 290 300
TGFFGDIIES IFKRDAHLKN SNKLKAVGGM LDTLDSLLLS TPIAYLFLLI
TQSKEFIG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE001363 Genomic DNA Translation: AAD18707.1 AE002161 Genomic DNA Translation: AAF38055.1 BA000008 Genomic DNA Translation: BAA98773.1 AE009440 Genomic DNA Translation: AAP98518.1 |
PIRi | C86561 H72062 |
RefSeqi | NP_224763.1, NC_000922.1 WP_010883205.1, NZ_LN847257.1 |
Genome annotation databases
EnsemblBacteriai | AAD18707; AAD18707; CPn_0567 AAF38055; AAF38055; CP_0182 |
GeneIDi | 45050611 |
KEGGi | cpa:CP_0182 cpj:cdsA cpn:CPn_0567 cpt:CpB0589 |
PATRICi | fig|115713.3.peg.632 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE001363 Genomic DNA Translation: AAD18707.1 AE002161 Genomic DNA Translation: AAF38055.1 BA000008 Genomic DNA Translation: BAA98773.1 AE009440 Genomic DNA Translation: AAP98518.1 |
PIRi | C86561 H72062 |
RefSeqi | NP_224763.1, NC_000922.1 WP_010883205.1, NZ_LN847257.1 |
3D structure databases
AlphaFoldDBi | Q9Z7Y6 |
SMRi | Q9Z7Y6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 115711.CP_0182 |
Genome annotation databases
EnsemblBacteriai | AAD18707; AAD18707; CPn_0567 AAF38055; AAF38055; CP_0182 |
GeneIDi | 45050611 |
KEGGi | cpa:CP_0182 cpj:cdsA cpn:CPn_0567 cpt:CpB0589 |
PATRICi | fig|115713.3.peg.632 |
Phylogenomic databases
eggNOGi | COG0575, Bacteria |
HOGENOMi | CLU_037294_3_3_0 |
OrthoDBi | 1533756at2 |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00614 |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | CDSA_CHLPN | |
Accessioni | Q9Z7Y6Primary (citable) accession number: Q9Z7Y6 Secondary accession number(s): Q9JQ17 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families