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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.By similarity

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei77Proton acceptorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processDNA damage, DNA repair

Enzyme and pathway databases

BRENDAi3.2.2.27 1311

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylase (EC:3.2.2.27)
Short name:
UDG
Gene namesi
Name:ung
Ordered Locus Names:CPn_0773, CP_1099, CpB0801
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001760831 – 236Uracil-DNA glycosylaseAdd BLAST236

Interactioni

Protein-protein interaction databases

STRINGi182082.CpB0801

Structurei

3D structure databases

ProteinModelPortaliQ9Z7D3
SMRiQ9Z7D3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105D5S Bacteria
COG0692 LUCA
HOGENOMiHOG000229528
KOiK03648
OMAiQANGLCF
OrthoDBiPOG091H03VL

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Z7D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNATIDQLP VSWQEQLPLC WREQLKEEWS KPYMQQLLIF LKQEYKEHTV
60 70 80 90 100
YPEENCVFSA LRSTPFDQVR VVILGQDPYP GKGQAHGLSF SVPEGQRLPP
110 120 130 140 150
SLINIFRELK TDLGIENHKG CLQSWANQGI LLLNTVLTVR AGEPFSHAGK
160 170 180 190 200
GWELFTDAIV TKLIQERTHI IFVLWGAAAR KKCELLFNSK HQHAVLSSPH
210 220 230
PSPLAAHRGF FGCSHFSKIN YLLNKLNKPM INWKLP
Length:236
Mass (Da):27,006
Last modified:May 1, 1999 - v1
Checksum:i1A734AD68B81AA03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA Translation: AAD18911.1
AE002161 Genomic DNA Translation: AAF38868.1
BA000008 Genomic DNA Translation: BAA98981.1
AE009440 Genomic DNA Translation: AAP98730.1
PIRiC86587
H72035
RefSeqiNP_224968.1, NC_000922.1
WP_010883410.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD18911; AAD18911; CPn_0773
AAF38868; AAF38868; CP_1099
AAP98730; AAP98730; CpB0801
BAA98981; BAA98981; BAA98981
GeneIDi895046
KEGGicpa:CP_1099
cpj:ung
cpn:CPn0773
cpt:CpB0801
PATRICifig|115713.3.peg.850

Similar proteinsi

Entry informationi

Entry nameiUNG_CHLPN
AccessioniPrimary (citable) accession number: Q9Z7D3
Secondary accession number(s): Q9JQB3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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