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Entry version 150 (13 Feb 2019)
Sequence version 1 (01 May 1999)
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Protein

Protein fem-1 homolog A-A

Gene

Fem1aa

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4 (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • negative regulation of inflammatory response Source: MGI
  • negative regulation of MAP kinase activity Source: MGI
  • regulation of ubiquitin-protein transferase activity Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-8951664 Neddylation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein fem-1 homolog A-A
Short name:
FEM1a-A
Alternative name(s):
FEM1-alpha-A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fem1aa
Synonyms:Fem1a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1335089 Fem1a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003245261 – 654Protein fem-1 homolog A-AAdd BLAST654

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Z2G1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Z2G1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Z2G1

PRoteomics IDEntifications database

More...
PRIDEi
Q9Z2G1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Z2G1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Z2G1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in adult heart and skeletal muscle.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed during embryogenesis.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000043683 Expressed in 264 organ(s), highest expression level in skeletal muscle tissue

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Z2G1 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
199630, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000057996

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Z2G1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati2 – 31ANK 1Add BLAST30
Repeati40 – 70ANK 2Add BLAST31
Repeati82 – 111ANK 3Add BLAST30
Repeati115 – 145ANK 4Add BLAST31
Repeati149 – 178ANK 5Add BLAST30
Repeati182 – 211ANK 6Add BLAST30
Repeati214 – 243ANK 7Add BLAST30
Repeati283 – 317TPR 1Add BLAST35
Repeati375 – 408TPR 2Add BLAST34
Repeati519 – 561ANK 8Add BLAST43
Repeati565 – 594ANK 9Add BLAST30

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the fem-1 family.Curated

Keywords - Domaini

ANK repeat, Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0508 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161210

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000008180

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057774

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Z2G1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CNARMER

Database of Orthologous Groups

More...
OrthoDBi
252380at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Z2G1

TreeFam database of animal gene trees

More...
TreeFami
TF351376

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit
1.25.40.20, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 2 hits
SSF48452 SSF48452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9Z2G1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLHTAVYNA AHDGKLPLLQ KLLAGRGREE LEELLGEVAG GGTPLLIAAR
60 70 80 90 100
RGHLDVVEYL VDHCGASVEA SGSVHFDGET IEGAPPLWAA SAAGHLAVVR
110 120 130 140 150
SLLRRGASVN RTTRTNSTPL RAACFDGHLD VVRYLVGEHK ADLEVANRHG
160 170 180 190 200
HTCLMISCYK GHREIARYLL ERGAQVNRRS AKGNTALHDC AESGSLEILQ
210 220 230 240 250
LLLGCHARME RDGYGMTPLL AASVTGHTNI VEYLIQEQPG HEQLSGTELP
260 270 280 290 300
GEGSSQVAGN HCSTPEEAEP YESCCPTSRE AAVEALELLG ATYVDKKRDL
310 320 330 340 350
LGALKHWRRA MELRHQGGGY LPKPEPQQLV LAYDYSREVT TPQELEALIT
360 370 380 390 400
DPDEMRMQAL LIRERILGPS HPDTSYYIRY RGAVYADSGN FERCIRLWKY
410 420 430 440 450
ALDMQQNNLE PLSPMTASSF LSFAELFSYV LQDRSAKGNL GMQLGFADLM
460 470 480 490 500
GVLSKGVREV ERALQLPKEP GDSAQFTKAI AIILHLLYLL EKVECTPSQE
510 520 530 540 550
HLKHQTVYRL LKCAPRGKNG FTPLHMAVDK ETTNVGRYRV GVFPSLQVVK
560 570 580 590 600
VLLDCGADPD SRDFDNNTPL HIAAQNNCPA IMDALIEAGA HMDATNAFKK
610 620 630 640 650
TAYELLDSKL LAKSTVQPFN YVTLQCLAAR ALDRNKVPYK GFIPEELEAF

IQLH
Length:654
Mass (Da):72,089
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7A17B38D8E7C63FB
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC28699 differs from that shown. Reason: Frameshift at position 30.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27G → E in BAE33219 (PubMed:16141072).Curated1
Sequence conflicti55D → E in BAC28699 (PubMed:16141072).Curated1
Sequence conflicti111R → S in BAB23768 (PubMed:16141072).Curated1
Sequence conflicti575Q → H in BAC38102 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF064447 Genomic DNA Translation: AAC82372.1
AK005041 mRNA Translation: BAB23768.1
AK034412 mRNA Translation: BAC28699.1 Frameshift.
AK075860 mRNA Translation: BAC36011.1
AK080978 mRNA Translation: BAC38102.1
AK147879 mRNA Translation: BAE28199.1
AK155363 mRNA Translation: BAE33219.1
BC009161 mRNA Translation: AAH09161.1
BC054382 mRNA Translation: AAH54382.1
BC110669 mRNA Translation: AAI10670.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS28899.1

NCBI Reference Sequences

More...
RefSeqi
NP_034322.3, NM_010192.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.290813
Mm.487343

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000060253; ENSMUSP00000057996; ENSMUSG00000043683

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
14154

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:14154

UCSC genome browser

More...
UCSCi
uc008dbk.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF064447 Genomic DNA Translation: AAC82372.1
AK005041 mRNA Translation: BAB23768.1
AK034412 mRNA Translation: BAC28699.1 Frameshift.
AK075860 mRNA Translation: BAC36011.1
AK080978 mRNA Translation: BAC38102.1
AK147879 mRNA Translation: BAE28199.1
AK155363 mRNA Translation: BAE33219.1
BC009161 mRNA Translation: AAH09161.1
BC054382 mRNA Translation: AAH54382.1
BC110669 mRNA Translation: AAI10670.1
CCDSiCCDS28899.1
RefSeqiNP_034322.3, NM_010192.4
UniGeneiMm.290813
Mm.487343

3D structure databases

ProteinModelPortaliQ9Z2G1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi199630, 2 interactors
STRINGi10090.ENSMUSP00000057996

PTM databases

iPTMnetiQ9Z2G1
PhosphoSitePlusiQ9Z2G1

Proteomic databases

EPDiQ9Z2G1
MaxQBiQ9Z2G1
PaxDbiQ9Z2G1
PRIDEiQ9Z2G1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000060253; ENSMUSP00000057996; ENSMUSG00000043683
GeneIDi14154
KEGGimmu:14154
UCSCiuc008dbk.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55527
MGIiMGI:1335089 Fem1a

Phylogenomic databases

eggNOGiKOG0508 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000161210
HOGENOMiHOG000008180
HOVERGENiHBG057774
InParanoidiQ9Z2G1
OMAiCNARMER
OrthoDBi252380at2759
PhylomeDBiQ9Z2G1
TreeFamiTF351376

Enzyme and pathway databases

UniPathwayi
UPA00143

ReactomeiR-MMU-8951664 Neddylation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Fem1a mouse

Protein Ontology

More...
PROi
PR:Q9Z2G1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000043683 Expressed in 264 organ(s), highest expression level in skeletal muscle tissue
GenevisibleiQ9Z2G1 MM

Family and domain databases

CDDicd00204 ANK, 3 hits
Gene3Di1.25.40.10, 1 hit
1.25.40.20, 4 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF12796 Ank_2, 3 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 9 hits
SUPFAMiSSF48403 SSF48403, 2 hits
SSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFM1AA_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Z2G1
Secondary accession number(s): Q3U2C2
, Q8C4V3, Q8C6D9, Q8CBW9, Q9DBC6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 1, 1999
Last modified: February 13, 2019
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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