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UniProtKB - Q9Z1Q9 (SYVC_MOUSE)

Entry version 165 (02 Jun 2021)
Sequence version 1 (01 May 1999)
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Protein

Valine--tRNA ligase

Gene

Vars1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Can be regulated by protein kinase C-dependent phosphorylation.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei864ATPBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

  • valyl-tRNA aminoacylation Source: GO_Central
Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Valine--tRNA ligase (EC:6.1.1.9)
Alternative name(s):
Protein G7a
Valyl-tRNA synthetase
Short name:
ValRS
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Vars1
Synonyms:Bat6, G7a, Vars, Vars2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:90675, Vars

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001062542 – 1263Valine--tRNA ligaseAdd BLAST1262

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
Modified residuei436PhosphoserineBy similarity1
Modified residuei526PhosphoserineBy similarity1
Modified residuei644N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Z1Q9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Z1Q9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Z1Q9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Z1Q9

PRoteomics IDEntifications database

More...PRIDEi		Q9Z1Q9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		262923

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Z1Q9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Z1Q9

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9Z1Q9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000007029, Expressed in testis and 250 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Z1Q9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Z1Q9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms high-molecular-mass aggregates with elongation factor 1.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		204498, 21 interactors

Protein interaction database and analysis system

More...IntActi		Q9Z1Q9, 5 interactors

Molecular INTeraction database

More...MINTi		Q9Z1Q9

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000084572

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Z1Q9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini89 – 219GST C-terminalAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni218 – 294DisorderedSequence analysisAdd BLAST77

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi343 – 353'HIGH' regionAdd BLAST11
Motifi861 – 865'KMSKS' region5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi233 – 249Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi256 – 276Basic and acidic residuesSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0432, Eukaryota
KOG0867, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157775

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001493_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Z1Q9

Identification of Orthologs from Complete Genome Data

More...OMAi		FATKLWN

Database of Orthologous Groups

More...OrthoDBi		229591at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Z1Q9

TreeFam database of animal gene trees

More...TreeFami		TF300648

Family and domain databases

Conserved Domains Database

More...CDDi		cd07962, Anticodon_Ia_Val, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.287.380, 1 hit
3.40.50.620, 1 hit
3.90.740.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_02004, Val_tRNA_synth_type1, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001412, aa-tRNA-synth_I_CS
IPR002300, aa-tRNA-synth_Ia
IPR033705, Anticodon_Ia_Val
IPR010987, Glutathione-S-Trfase_C-like
IPR036282, Glutathione-S-Trfase_C_sf
IPR004046, GST_C
IPR013155, M/V/L/I-tRNA-synth_anticd-bd
IPR014729, Rossmann-like_a/b/a_fold
IPR009080, tRNAsynth_Ia_anticodon-bd
IPR037118, Val-tRNA_synth_C_sf
IPR009008, Val/Leu/Ile-tRNA-synth_edit
IPR002303, Valyl-tRNA_ligase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08264, Anticodon_1, 1 hit
PF00043, GST_C, 1 hit
PF00133, tRNA-synt_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00986, TRNASYNTHVAL

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47323, SSF47323, 1 hit
SSF47616, SSF47616, 1 hit
SSF50677, SSF50677, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00422, valS, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00178, AA_TRNA_LIGASE_I, 1 hit
PS50405, GST_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q9Z1Q9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSILYVSPHP DAFPSLRALI AARYGEAGDG PGWGGPHPRI CLQPPPSSRT 
        60         70         80         90        100
PFPPPRLPAL EQGPGGLWVW GAPAVAQLLW PAGLGGPGGS RAAVLVQQWV 
       110        120        130        140        150
SYADTELIPA ACGATLPALG LRGPGQDPQA ALGALGKALN PLEDWLRLHT 
       160        170        180        190        200
YLAGDAPTLA DLAAVTALLL PFRYVLDPSA RRIWGNVTRW FNTCVRQPEF 
       210        220        230        240        250
RAVLGEVALY SGARSVTQQP GSEVIAPQKT PAQLKKEAKK REKLEKFQQK 
       260        270        280        290        300
QKTQQQPPHG EKKPKPEKKE KRDPGVITYD LPTPPGEKKD VSGAMPDSYS 
       310        320        330        340        350
PQYVEAAWYP WWERQGFFKP EYGRPSVSAP NPRGVFMMCI PPPNVTGSLH 
       360        370        380        390        400
LGHALTNAIQ DSLTRWHRMR GETTLWNPGC DHAGIATQVV VEKKLWKERG 
       410        420        430        440        450
LNRHQLGREA FLEEVWKWKA EKGDRIYHQL KKLGSSLDWD RACFTMDPKL 
       460        470        480        490        500
SATVTEAFVR LHEEGVIYRS TRLVNWSCTL NSAISDIEVD KKELTGRTLL 
       510        520        530        540        550
PVPGYKEKVE FGVLVSFAYK VQGSDSDEEV VVATTRIETM LGDVAVAVHP 
       560        570        580        590        600
KDPRYQHLKG KCVVHPFLSR SLPIVFDDFV DMEFGTGAVK ITPAHDQNDY 
       610        620        630        640        650
EVGQRHRLEA ISIMDSKGAL INVPPPFLGL PRFEARKAVL AALKERGLFR 
       660        670        680        690        700
GVKDNPMVVP LCNRSKDVVE PLLRPQWYVR CGEMAQAASA AVTRGDLRIL 
       710        720        730        740        750
PEAHQRTWHS WMDNIRDWCI SRQLWWGHRI PAYFITVHDP AVPPGEDPDG 
       760        770        780        790        800
RYWVSGRTEA EAREKAAREF GVSPDKISLQ QDEDVLDTWF SSGLFPFSIF 
       810        820        830        840        850
GWPNQSEDLS VFYPGTLLET GHDILFFWVA RMVMLGLKLT GKLPFREVYL 
       860        870        880        890        900
HAIVRDAHGR KMSKSLGNVI DPLDVIHGVS LQGLYDQLLN SNLDPSEVEK 
       910        920        930        940        950
AKEGQKADFP AGIPECGTDA LRFGLCAYTS QGRDINLDVN RILGYRHFCN 
       960        970        980        990       1000
KLWNATKFAL RGLGKGFVPS ATSKPEGHES LVDRWIRSRL TEAVRLSNEG 
      1010       1020       1030       1040       1050
FQAYDFPAIT TAQYSFWLYE LCDVYLECLK PVLNGVDQVA AECARQTLYT 
      1060       1070       1080       1090       1100
CLDVGLRLLS PFMPFVTEEL FQRLPRRTPK APASLCVTPY PEPSECSWKD 
      1110       1120       1130       1140       1150
PEAEAALELA LSITRAVRSL RADYNLTRTR PDCFLEVADE ATGALASAVS 
      1160       1170       1180       1190       1200
GYVQALASAG VVAVLALGAP APQGCAVAVA SDRCSIHLQL QGLVDPAREL 
      1210       1220       1230       1240       1250
GKLQAKRSEA QRQAQRLQER RAASSYSAKV PLEVQEADEA KLQQTEAELR 
      1260 
KVDEAIALFQ KML
Length:1,263
Mass (Da):140,215
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB510E73284FCE26D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3UY93G3UY93_MOUSE
Valyl-tRNA synthetase
Vars
1,278Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZX1G3UZX1_MOUSE
Valyl-tRNA synthetase
Vars
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UYW2G3UYW2_MOUSE
Valyl-tRNA synthetase
Vars
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZ22G3UZ22_MOUSE
Valyl-tRNA synthetase
Vars
230Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti959A → R in AAD26532 (PubMed:10199925).Curated1
Sequence conflicti959A → R in AAD26531 (PubMed:10199925).Curated1
Sequence conflicti1219E → K in AAD26532 (PubMed:10199925).Curated1
Sequence conflicti1219E → K in AAD26531 (PubMed:10199925).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF087680 mRNA Translation: AAD26532.1
AF087141 Genomic DNA Translation: AAD26531.1
AF109905 Genomic DNA Translation: AAC84151.1
AF109906 Genomic DNA Translation: AAC84172.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS37593.1

NCBI Reference Sequences

More...RefSeqi		NP_035820.3, NM_011690.3
XP_017172884.1, XM_017317395.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000087315; ENSMUSP00000084572; ENSMUSG00000007029

Database of genes from NCBI RefSeq genomes

More...GeneIDi		22321

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:22321

UCSC genome browser

More...UCSCi		uc008cez.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF087680 mRNA Translation: AAD26532.1
AF087141 Genomic DNA Translation: AAD26531.1
AF109905 Genomic DNA Translation: AAC84151.1
AF109906 Genomic DNA Translation: AAC84172.1
CCDSiCCDS37593.1
RefSeqiNP_035820.3, NM_011690.3
XP_017172884.1, XM_017317395.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi204498, 21 interactors
IntActiQ9Z1Q9, 5 interactors
MINTiQ9Z1Q9
STRINGi10090.ENSMUSP00000084572

PTM databases

iPTMnetiQ9Z1Q9
PhosphoSitePlusiQ9Z1Q9
SwissPalmiQ9Z1Q9

Proteomic databases

EPDiQ9Z1Q9
jPOSTiQ9Z1Q9
MaxQBiQ9Z1Q9
PaxDbiQ9Z1Q9
PRIDEiQ9Z1Q9
ProteomicsDBi262923

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		51277, 180 antibodies

The DNASU plasmid repository

More...DNASUi		22321

Genome annotation databases

EnsembliENSMUST00000087315; ENSMUSP00000084572; ENSMUSG00000007029
GeneIDi22321
KEGGimmu:22321
UCSCiuc008cez.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		22321
MGIiMGI:90675, Vars

Phylogenomic databases

eggNOGiKOG0432, Eukaryota
KOG0867, Eukaryota
GeneTreeiENSGT00940000157775
HOGENOMiCLU_001493_0_1_1
InParanoidiQ9Z1Q9
OMAiFATKLWN
OrthoDBi229591at2759
PhylomeDBiQ9Z1Q9
TreeFamiTF300648

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		22321, 19 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Vars, mouse

Protein Ontology

More...PROi		PR:Q9Z1Q9
RNActiQ9Z1Q9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000007029, Expressed in testis and 250 other tissues
ExpressionAtlasiQ9Z1Q9, baseline and differential
GenevisibleiQ9Z1Q9, MM

Family and domain databases

CDDicd07962, Anticodon_Ia_Val, 1 hit
Gene3Di1.10.287.380, 1 hit
3.40.50.620, 1 hit
3.90.740.10, 1 hit
HAMAPiMF_02004, Val_tRNA_synth_type1, 1 hit
InterProiView protein in InterPro
IPR001412, aa-tRNA-synth_I_CS
IPR002300, aa-tRNA-synth_Ia
IPR033705, Anticodon_Ia_Val
IPR010987, Glutathione-S-Trfase_C-like
IPR036282, Glutathione-S-Trfase_C_sf
IPR004046, GST_C
IPR013155, M/V/L/I-tRNA-synth_anticd-bd
IPR014729, Rossmann-like_a/b/a_fold
IPR009080, tRNAsynth_Ia_anticodon-bd
IPR037118, Val-tRNA_synth_C_sf
IPR009008, Val/Leu/Ile-tRNA-synth_edit
IPR002303, Valyl-tRNA_ligase
PfamiView protein in Pfam
PF08264, Anticodon_1, 1 hit
PF00043, GST_C, 1 hit
PF00133, tRNA-synt_1, 1 hit
PRINTSiPR00986, TRNASYNTHVAL
SUPFAMiSSF47323, SSF47323, 1 hit
SSF47616, SSF47616, 1 hit
SSF50677, SSF50677, 1 hit
TIGRFAMsiTIGR00422, valS, 1 hit
PROSITEiView protein in PROSITE
PS00178, AA_TRNA_LIGASE_I, 1 hit
PS50405, GST_CTER, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYVC_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Z1Q9
Secondary accession number(s): Q9QUN2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: June 2, 2021
This is version 165 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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