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UniProtKB - Q9Z150 (Q9Z150_MOUSE)
Protein
Submitted name:
Zinc finger and BTB domain-containing 12
Gene
Zbtb12
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: MGI
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger and BTB domain-containing 12 |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:88133, Zbtb12 |
VEuPathDBi | HostDB:ENSMUSG00000049823 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000049823, Expressed in brain and 176 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9Z150, 1 interactor |
STRINGi | 10090.ENSMUSP00000057515 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 33 – 97 | BTBInterPro annotationAdd BLAST | 65 | |
Domaini | 359 – 386 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 387 – 414 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 415 – 443 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 154 – 178 | DisorderedSequence analysisAdd BLAST | 25 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 157 – 178 | Pro residuesSequence analysisAdd BLAST | 22 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162418 |
HOGENOMi | CLU_037856_0_0_1 |
OMAi | HFHHSTN |
OrthoDBi | 1318335at2759 |
TreeFami | TF333162 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9Z150-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASGVEVLRF QLPGHEAATL RNMNQLRAEE RFCDVTIVAD SLKFRGHKVI
60 70 80 90 100
LAACSPFLRD QFLLNPSSEL QVSLMHSARI VADLLLSCYT GALEFAVRDI
110 120 130 140 150
VNYLTAASYL QMEHVVEKCR NALSQFIEPK IGLKEDGVSE ASLLSSVSAT
160 170 180 190 200
KSLLPPARTP KPAPKPPPPP PLPPPLLRPV KLEFPLDEDL ELKAEEEDED
210 220 230 240 250
EDEDVSDICI VKVESALEVA HRLKPPGSLA GGLGIGASVS SHLGELAQSS
260 270 280 290 300
VAPNTVTPPQ GVVKACYSLS EDAEGEGLLL IPGGRASVGA TSGLVEAAAV
310 320 330 340 350
AMAARGAGGS LGAGGSRGPL PGGFSSGNPL KNIKCTKCPE VFQGVEKLVF
360 370 380 390 400
HMRAQHFIFM CPRCGKQFNH SSNLNRHMNV HRGVKSHSCG ICGKCFTQKS
410 420 430 440 450
TLHDHLNLHS GARPYRCSYC DVRFAHKPAI RRHLKEQHGK TTAENVLEAG
VAEINVLIR
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketG3UY12 | G3UY12_MOUSE | Zinc finger and BTB domain-containi... | Zbtb12 | 68 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF109906 Genomic DNA Translation: AAC84163.1 AK135305 mRNA Translation: BAE22484.1 |
RefSeqi | NP_942589.3, NM_198886.3 XP_006523953.1, XM_006523890.3 |
Genome annotation databases
Ensembli | ENSMUST00000052778.10; ENSMUSP00000057515.9; ENSMUSG00000049823.10 |
GeneIDi | 193736 |
KEGGi | mmu:193736 |
UCSCi | uc008cea.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF109906 Genomic DNA Translation: AAC84163.1 AK135305 mRNA Translation: BAE22484.1 |
RefSeqi | NP_942589.3, NM_198886.3 XP_006523953.1, XM_006523890.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9Z150, 1 interactor |
STRINGi | 10090.ENSMUSP00000057515 |
Proteomic databases
ProteomicsDBi | 336930 |
Protocols and materials databases
Antibodypediai | 28048, 89 antibodies from 16 providers |
DNASUi | 193736 |
Genome annotation databases
Ensembli | ENSMUST00000052778.10; ENSMUSP00000057515.9; ENSMUSG00000049823.10 |
GeneIDi | 193736 |
KEGGi | mmu:193736 |
UCSCi | uc008cea.1, mouse |
Organism-specific databases
CTDi | 221527 |
MGIi | MGI:88133, Zbtb12 |
VEuPathDBi | HostDB:ENSMUSG00000049823 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162418 |
HOGENOMi | CLU_037856_0_0_1 |
OMAi | HFHHSTN |
OrthoDBi | 1318335at2759 |
TreeFami | TF333162 |
Miscellaneous databases
BioGRID-ORCSi | 193736, 3 hits in 74 CRISPR screens |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000049823, Expressed in brain and 176 other tissues |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9Z150_MOUSE | |
Accessioni | Q9Z150Primary (citable) accession number: Q9Z150 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 1999 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 176 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |