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Entry version 108 (16 Oct 2019)
Sequence version 1 (01 May 1999)
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Protein

Xenotropic and polytropic retrovirus receptor 1

Gene

Xpr1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses (PubMed:10516044, PubMed:9988277).By similarity2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei22Important for inositol polyphosphate bindingBy similarity1
Sitei26Important for inositol polyphosphate bindingBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHost cell receptor for virus entry, Receptor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Xenotropic and polytropic retrovirus receptor 1
Alternative name(s):
Protein SYG1 homolog
Rmc-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Xpr1
Synonyms:Syg1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97932 Xpr1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 236CytoplasmicSequence analysisAdd BLAST236
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei237 – 257HelicalSequence analysisAdd BLAST21
Topological domaini258 – 264ExtracellularSequence analysis7
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Topological domaini286 – 314CytoplasmicSequence analysisAdd BLAST29
Transmembranei315 – 337HelicalSequence analysisAdd BLAST23
Topological domaini338 – 340ExtracellularSequence analysis3
Transmembranei341 – 360HelicalSequence analysisAdd BLAST20
Topological domaini361 – 376CytoplasmicSequence analysisAdd BLAST16
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 402ExtracellularSequence analysis5
Transmembranei403 – 423HelicalSequence analysisAdd BLAST21
Topological domaini424 – 475CytoplasmicSequence analysisAdd BLAST52
Transmembranei476 – 498HelicalSequence analysisAdd BLAST23
Topological domaini499 – 507ExtracellularSequence analysis9
Transmembranei508 – 528HelicalSequence analysisAdd BLAST21
Topological domaini529 – 695CytoplasmicSequence analysisAdd BLAST167

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi500E → K: Gives susceptibility to xenotropic murine leukemia retroviruses infection. 1 Publication1
Mutagenesisi582T → TT: Gives susceptibility to xenotropic murine leukemia retroviruses infection. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003158541 – 695Xenotropic and polytropic retrovirus receptor 1Add BLAST695

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei667PhosphoserineCombined sources1
Modified residuei689PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Z0U0

PeptideAtlas

More...
PeptideAtlasi
Q9Z0U0

PRoteomics IDEntifications database

More...
PRIDEi
Q9Z0U0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Z0U0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Z0U0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000026469 Expressed in 296 organ(s), highest expression level in forebrain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Z0U0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Z0U0 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000027741

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Z0U0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 177SPXPROSITE-ProRule annotationAdd BLAST177
Domaini439 – 642EXSPROSITE-ProRule annotationAdd BLAST204

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni158 – 165Important for inositol polyphosphate bindingBy similarity8

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SPX domain has high affinity for inositol polyphosphates, such as myo-inositol hexakisphosphate and 5-diphospho-myo-inositol pentakisphosphate (5-InsP7). Its affinity for inorganic phosphate is tow to three orders of magnitude lower.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1162 Eukaryota
COG5409 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00500000044895

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Z0U0

Identification of Orthologs from Complete Genome Data

More...
OMAi
FTNGNWT

Database of Orthologous Groups

More...
OrthoDBi
536327at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Z0U0

TreeFam database of animal gene trees

More...
TreeFami
TF314643

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004342 EXS_C
IPR004331 SPX_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03124 EXS, 1 hit
PF03105 SPX, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51380 EXS, 1 hit
PS51382 SPX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Z0U0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKFAEHLSAH ITPEWRKQYI QYEAFKDMLY SAQDQAPSVE VTDEDTVKRY
60 70 80 90 100
FAKFEEKFFQ TCEKELAKIN TFYSEKLAEA QRRFATLQNE LQSSLDVQKE
110 120 130 140 150
SSGVTTLRQR RKPVFHLSHE ERVQHRNIKD LKLAFSEFYL SLILLQNYQN
160 170 180 190 200
LNFTGFRKIL KKHDKILETS RGADWRVIHV EVAPFYTCKK INQLISETEA
210 220 230 240 250
VVTNELEDGD RQKAMKRLRV PPLGAAQPAP AWTTFRVGLF CGIFIVLNIT
260 270 280 290 300
LVFAAVFKLE TDRTVWPLIR IYRGGFLLIE FLFLLGINTY GWRQAGVNHV
310 320 330 340 350
LIFELNPRNN LSHQHLFEIA GFLGILWCLS LLACFFAPIS IIPIYVYPLA
360 370 380 390 400
LYGFMVFFLI NPTKTFYYKS RFWLLKLLFR VFTAPFHKVG FADFWLADQL
410 420 430 440 450
NSLSVILMDL EYMICFYSFE LKWDESKGLL PNDPQEPEFC HKYSYGVRAI
460 470 480 490 500
VQCIPAWLRF IQCLRRYRDT RRAFPHLVNA GKYSTTFFTV TFAALYSTHE
510 520 530 540 550
EQNHSDTVVF FYLWVFFCII SSCYTLIWDL KMDWGLFDKN AGENTFLREE
560 570 580 590 600
IVYPQKAYYY CAIIEDVILR FAWTIQISIT ATFKPHVGNI IATVFAPLEV
610 620 630 640 650
FRRFVWNFFR LENEHLNNCG EFRAVRDISV APLNADDQTL LEQMMDQEDG
660 670 680 690
VRNRQKNRSW KYNQSISLRR PRLASQSKAR DTKVLIEDTD DEANT
Length:695
Mass (Da):81,751
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB2E76CFE29C72258
GO
Isoform 2 (identifier: Q9Z0U0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     677-695: SKARDTKVLIEDTDDEANT → YVE

Note: No experimental confirmation available.
Show »
Length:679
Mass (Da):80,040
Checksum:i1E79B7D83133CC1B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z2B4D3Z2B4_MOUSE
Xenotropic and polytropic retroviru...
Xpr1
630Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti59F → S in AAF13256 (Ref. 3) Curated1
Sequence conflicti72F → L in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti103G → A in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti106T → A in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti158K → E in BAE27891 (PubMed:16141072).Curated1
Sequence conflicti372F → L in AAF03482 (PubMed:10516044).Curated1
Sequence conflicti377L → P in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti469D → N in AAF03482 (PubMed:10516044).Curated1
Sequence conflicti500 – 503EEQN → KERG in AAF03484 (PubMed:10516044).Curated4
Sequence conflicti508V → M in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti515 – 518VFFC → IVFY in AAF03484 (PubMed:10516044).Curated4
Sequence conflicti564I → T in AAF13256 (Ref. 3) Curated1
Sequence conflicti582T → TT in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti589N → D in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti591I → S in BAE27891 (PubMed:16141072).Curated1
Sequence conflicti606W → L in AAF03484 (PubMed:10516044).Curated1
Sequence conflicti647Q → R in BAE24789 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_030749677 – 695SKARD…DEANT → YVE in isoform 2. 1 PublicationAdd BLAST19

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF131096 mRNA Translation: AAF03482.1
AF131098 mRNA Translation: AAF03484.1
AF114753 mRNA Translation: AAD17206.1
AF198104 mRNA Translation: AAF13256.1
AK032148 mRNA Translation: BAC27724.1
AK033421 mRNA Translation: BAC28279.1
AK141660 mRNA Translation: BAE24789.1
AK147403 mRNA Translation: BAE27891.1
BC153872 mRNA Translation: AAI53873.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15384.1 [Q9Z0U0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_035403.1, NM_011273.2 [Q9Z0U0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000027741; ENSMUSP00000027741; ENSMUSG00000026469 [Q9Z0U0-1]
ENSMUST00000111774; ENSMUSP00000107404; ENSMUSG00000026469 [Q9Z0U0-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
19775

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:19775

UCSC genome browser

More...
UCSCi
uc007dbf.1 mouse [Q9Z0U0-1]
uc007dbh.1 mouse [Q9Z0U0-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF131096 mRNA Translation: AAF03482.1
AF131098 mRNA Translation: AAF03484.1
AF114753 mRNA Translation: AAD17206.1
AF198104 mRNA Translation: AAF13256.1
AK032148 mRNA Translation: BAC27724.1
AK033421 mRNA Translation: BAC28279.1
AK141660 mRNA Translation: BAE24789.1
AK147403 mRNA Translation: BAE27891.1
BC153872 mRNA Translation: AAI53873.1
CCDSiCCDS15384.1 [Q9Z0U0-1]
RefSeqiNP_035403.1, NM_011273.2 [Q9Z0U0-1]

3D structure databases

SMRiQ9Z0U0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027741

PTM databases

iPTMnetiQ9Z0U0
PhosphoSitePlusiQ9Z0U0

Proteomic databases

PaxDbiQ9Z0U0
PeptideAtlasiQ9Z0U0
PRIDEiQ9Z0U0

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
19775

Genome annotation databases

EnsembliENSMUST00000027741; ENSMUSP00000027741; ENSMUSG00000026469 [Q9Z0U0-1]
ENSMUST00000111774; ENSMUSP00000107404; ENSMUSG00000026469 [Q9Z0U0-2]
GeneIDi19775
KEGGimmu:19775
UCSCiuc007dbf.1 mouse [Q9Z0U0-1]
uc007dbh.1 mouse [Q9Z0U0-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9213
MGIiMGI:97932 Xpr1

Phylogenomic databases

eggNOGiKOG1162 Eukaryota
COG5409 LUCA
GeneTreeiENSGT00500000044895
InParanoidiQ9Z0U0
OMAiFTNGNWT
OrthoDBi536327at2759
PhylomeDBiQ9Z0U0
TreeFamiTF314643

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Xpr1 mouse

Protein Ontology

More...
PROi
PR:Q9Z0U0

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000026469 Expressed in 296 organ(s), highest expression level in forebrain
ExpressionAtlasiQ9Z0U0 baseline and differential
GenevisibleiQ9Z0U0 MM

Family and domain databases

InterProiView protein in InterPro
IPR004342 EXS_C
IPR004331 SPX_dom
PfamiView protein in Pfam
PF03124 EXS, 1 hit
PF03105 SPX, 3 hits
PROSITEiView protein in PROSITE
PS51380 EXS, 1 hit
PS51382 SPX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiXPR1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Z0U0
Secondary accession number(s): Q3UHG6
, Q3UR99, Q8CCC8, Q8CCT2, Q9QZ72, Q9R034, Q9R036
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 1, 1999
Last modified: October 16, 2019
This is version 108 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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