UniProtKB - Q9YFN1 (RL2_AERPE)
Protein
50S ribosomal protein L2
Gene
rpl2
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Functioni
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L2UniRule annotation |
Gene namesi | Name:rpl2UniRule annotation Ordered Locus Names:APE_0218 |
Organismi | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) |
Taxonomic identifieri | 272557 [NCBI] |
Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum › |
Proteomesi |
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PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000129710 | 1 – 238 | 50S ribosomal protein L2Add BLAST | 238 |
Proteomic databases
PRIDEi | Q9YFN1 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
Forms a bridge to the 30S subunit in the 70S ribosome.
UniRule annotationProtein-protein interaction databases
STRINGi | 272557.APE_0218 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL2 family.UniRule annotation
Phylogenomic databases
eggNOGi | arCOG04067, Archaea |
OMAi | SCIELRP |
Family and domain databases
Gene3Di | 2.30.30.30, 1 hit 4.10.950.10, 1 hit |
HAMAPi | MF_01320_A, Ribosomal_L2_A, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR022666, Rbsml_prot_L2_RNA-bd_dom IPR014722, Rib_L2_dom2 IPR002171, Ribosomal_L2 IPR023672, Ribosomal_L2_arc IPR022669, Ribosomal_L2_C IPR022671, Ribosomal_L2_CS IPR014726, Ribosomal_L2_dom3 IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR13691, PTHR13691, 1 hit |
Pfami | View protein in Pfam PF00181, Ribosomal_L2, 1 hit PF03947, Ribosomal_L2_C, 1 hit |
PIRSFi | PIRSF002158, Ribosomal_L2, 1 hit |
SMARTi | View protein in SMART SM01383, Ribosomal_L2, 1 hit SM01382, Ribosomal_L2_C, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00467, RIBOSOMAL_L2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9YFN1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKRLRQQRA GRGTPTYRSR AHIHPGPAKY PPLSGDTLRG KVVELIHDPG
60 70 80 90 100
RYVPLARVVR EDGVEFLMPA AEGMYVGQII EIGPAAKPEA GNILPLGKIP
110 120 130 140 150
EGTEVFNVEL RPGDGGKLAR QAGSYALVVG RAGAKTILRL PSGKDKEVPN
160 170 180 190 200
DSRATIGIPA GAGRIEKPIM KAGFAYHKWK VKARKWPRVR GVAMNAVDHP
210 220 230
FGGGRHQHKG RPSTVARTAP PGRKVGHIAA RRTGRRKR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000002 Genomic DNA Translation: BAA79130.1 |
PIRi | H72778 |
Genome annotation databases
EnsemblBacteriai | BAA79130; BAA79130; APE_0218 |
KEGGi | ape:APE_0218 |
PATRICi | fig|272557.25.peg.155 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000002 Genomic DNA Translation: BAA79130.1 |
PIRi | H72778 |
3D structure databases
SMRi | Q9YFN1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272557.APE_0218 |
Proteomic databases
PRIDEi | Q9YFN1 |
Genome annotation databases
EnsemblBacteriai | BAA79130; BAA79130; APE_0218 |
KEGGi | ape:APE_0218 |
PATRICi | fig|272557.25.peg.155 |
Phylogenomic databases
eggNOGi | arCOG04067, Archaea |
OMAi | SCIELRP |
Family and domain databases
Gene3Di | 2.30.30.30, 1 hit 4.10.950.10, 1 hit |
HAMAPi | MF_01320_A, Ribosomal_L2_A, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR022666, Rbsml_prot_L2_RNA-bd_dom IPR014722, Rib_L2_dom2 IPR002171, Ribosomal_L2 IPR023672, Ribosomal_L2_arc IPR022669, Ribosomal_L2_C IPR022671, Ribosomal_L2_CS IPR014726, Ribosomal_L2_dom3 IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR13691, PTHR13691, 1 hit |
Pfami | View protein in Pfam PF00181, Ribosomal_L2, 1 hit PF03947, Ribosomal_L2_C, 1 hit |
PIRSFi | PIRSF002158, Ribosomal_L2, 1 hit |
SMARTi | View protein in SMART SM01383, Ribosomal_L2, 1 hit SM01382, Ribosomal_L2_C, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00467, RIBOSOMAL_L2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL2_AERPE | |
Accessioni | Q9YFN1Primary (citable) accession number: Q9YFN1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | November 1, 1999 | |
Last modified: | December 2, 2020 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - SIMILARITY comments
Index of protein domains and families