UniProtKB - Q9YF35 (VATA_AERPE)
Protein
V-type ATP synthase alpha chain
Gene
atpA
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Functioni
Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit (By similarity).By similarity
Catalytic activityi
- EC:7.1.2.2
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 241 – 248 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- proton-transporting ATPase activity, rotational mechanism Source: UniProtKB-EC
- proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-UniRule
GO - Biological processi
- plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-UniRule
Keywordsi
Molecular function | Translocase |
Biological process | ATP synthesis, Hydrogen ion transport, Ion transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:atpA Ordered Locus Names:APE_0405.1 |
Organismi | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) |
Taxonomic identifieri | 272557 [NCBI] |
Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum › |
Proteomesi |
|
Subcellular locationi
Other locations
- proton-transporting two-sector ATPase complex, catalytic domain Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000144591 | 1 – 597 | V-type ATP synthase alpha chainAdd BLAST | 597 |
Proteomic databases
PRIDEi | Q9YF35 |
Family & Domainsi
Sequence similaritiesi
Belongs to the ATPase alpha/beta chains family.Curated
Phylogenomic databases
eggNOGi | arCOG00868, Archaea |
Family and domain databases
Gene3Di | 1.10.1140.10, 1 hit 2.40.30.20, 1 hit |
HAMAPi | MF_00309, ATP_synth_A_arch, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR031686, ATP-synth_a_Xtn IPR023366, ATP_synth_asu-like_sf IPR005726, ATP_synth_asu_arc IPR020003, ATPase_a/bsu_AS IPR004100, ATPase_F1/V1/A1_a/bsu_N IPR036121, ATPase_F1/V1/A1_a/bsu_N_sf IPR000194, ATPase_F1/V1/A1_a/bsu_nucl-bd IPR024034, ATPase_F1/V1_b/a_C IPR027417, P-loop_NTPase IPR022878, V-ATPase_asu |
PANTHERi | PTHR43607, PTHR43607, 1 hit |
Pfami | View protein in Pfam PF00006, ATP-synt_ab, 1 hit PF02874, ATP-synt_ab_N, 1 hit PF16886, ATP-synt_ab_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF50615, SSF50615, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01043, ATP_syn_A_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00152, ATPASE_ALPHA_BETA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9YF35-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVKGSIVRI SGPLVVAEGM SGAQMYEMVY VGEDRLIGEI TRIRGDRAFI
60 70 80 90 100
QVYESTSGLK PGEPVVGTGA PLSVELGPGL LGTIYDGVQR PLPIIAEKVA
110 120 130 140 150
EVDPRRRMFV ERGIQAPPLP RDRKFHFKPE PLKEGDKVEG GDALGRVPET
160 170 180 190 200
SLIEHVVMVP PGIRGRLKWL ASEGDYSVED TIAVVERDGR DVEIRMHQRW
210 220 230 240 250
PVRIPRPFKE KLEPQLPLIT GVRIIDTFFP MAKGGTGAVP GGFGTGKTVT
260 270 280 290 300
LHSLAQWSEA RVVIYIGCGE RGNEMTEVLE RFPQYKDPWT GKPLMDRTVL
310 320 330 340 350
IANTSNMPVA AREASIYVGI TIAEYYRDMG YDVLLVADST SRWAEALREI
360 370 380 390 400
AGRLEEMPAE EGYPSYLASR LAEFYERAGR VKALGSPERS GSVTVVGAVS
410 420 430 440 450
PPGGDFSEPV TSHTTRFIRV FWALDTKLAY SRHYPAINWL MSYSAYVDLV
460 470 480 490 500
TQWWHENVDK RWREYRDEAM DILLRESELQ EIVRLVGTEG LDEKDKMVLE
510 520 530 540 550
TARLIKDGFL KQNAFDPIDA FATPQKQFRL LKMIMDIHRK SLELIEKGVT
560 570 580 590
TQQILQALGR LYIDIVKAKF TIPNDQLEKI DEIRDRALKA LDELVSG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000002 Genomic DNA Translation: BAA79361.2 |
PIRi | E72733 |
Genome annotation databases
EnsemblBacteriai | BAA79361; BAA79361; APE_0405.1 |
KEGGi | ape:APE_0405.1 |
PATRICi | fig|272557.25.peg.302 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000002 Genomic DNA Translation: BAA79361.2 |
PIRi | E72733 |
3D structure databases
SMRi | Q9YF35 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272557.APE_0405.1 |
Proteomic databases
PRIDEi | Q9YF35 |
Genome annotation databases
EnsemblBacteriai | BAA79361; BAA79361; APE_0405.1 |
KEGGi | ape:APE_0405.1 |
PATRICi | fig|272557.25.peg.302 |
Phylogenomic databases
eggNOGi | arCOG00868, Archaea |
Family and domain databases
Gene3Di | 1.10.1140.10, 1 hit 2.40.30.20, 1 hit |
HAMAPi | MF_00309, ATP_synth_A_arch, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR031686, ATP-synth_a_Xtn IPR023366, ATP_synth_asu-like_sf IPR005726, ATP_synth_asu_arc IPR020003, ATPase_a/bsu_AS IPR004100, ATPase_F1/V1/A1_a/bsu_N IPR036121, ATPase_F1/V1/A1_a/bsu_N_sf IPR000194, ATPase_F1/V1/A1_a/bsu_nucl-bd IPR024034, ATPase_F1/V1_b/a_C IPR027417, P-loop_NTPase IPR022878, V-ATPase_asu |
PANTHERi | PTHR43607, PTHR43607, 1 hit |
Pfami | View protein in Pfam PF00006, ATP-synt_ab, 1 hit PF02874, ATP-synt_ab_N, 1 hit PF16886, ATP-synt_ab_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF50615, SSF50615, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01043, ATP_syn_A_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00152, ATPASE_ALPHA_BETA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | VATA_AERPE | |
Accessioni | Q9YF35Primary (citable) accession number: Q9YF35 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 24, 2001 |
Last sequence update: | June 26, 2007 | |
Last modified: | December 2, 2020 | |
This is version 124 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families