UniProtKB - Q9Y8H8 (SODF_AERPE)
Protein
Superoxide dismutase [Mn/Fe]
Gene
sod
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Functioni
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activityi
- EC:1.15.1.1
Cofactori
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 31 | Manganese or ironBy similarity | 1 | |
Metal bindingi | 79 | Manganese or ironBy similarity | 1 | |
Metal bindingi | 165 | Manganese or ironBy similarity | 1 | |
Metal bindingi | 169 | Manganese or ironBy similarity | 1 |
GO - Molecular functioni
- identical protein binding Source: IntAct
- metal ion binding Source: UniProtKB-KW
- superoxide dismutase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Oxidoreductase |
Ligand | Iron, Manganese, Metal-binding |
Enzyme and pathway databases
BRENDAi | 1.15.1.1, 171 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:sod Ordered Locus Names:APE_0741 |
Organismi | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) |
Taxonomic identifieri | 272557 [NCBI] |
Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000160005 | 1 – 214 | Superoxide dismutase [Mn/Fe]Add BLAST | 214 |
Interactioni
Binary interactionsi
Q9Y8H8
With | #Exp. | IntAct |
---|---|---|
itself | 3 | EBI-8549588,EBI-8549588 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
MINTi | Q9Y8H8 |
STRINGi | 272557.APE_0741 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q9Y8H8 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9Y8H8 |
Family & Domainsi
Sequence similaritiesi
Belongs to the iron/manganese superoxide dismutase family.Curated
Phylogenomic databases
eggNOGi | arCOG04147, Archaea |
OMAi | KWGSFDK |
Family and domain databases
Gene3Di | 1.10.287.990, 1 hit 2.40.500.20, 1 hit |
InterProi | View protein in InterPro IPR001189, Mn/Fe_SOD IPR019833, Mn/Fe_SOD_BS IPR019832, Mn/Fe_SOD_C IPR019831, Mn/Fe_SOD_N IPR036324, Mn/Fe_SOD_N_sf IPR036314, SOD_C_sf |
Pfami | View protein in Pfam PF02777, Sod_Fe_C, 1 hit PF00081, Sod_Fe_N, 1 hit |
PIRSFi | PIRSF000349, SODismutase, 1 hit |
PRINTSi | PR01703, MNSODISMTASE |
SUPFAMi | SSF46609, SSF46609, 1 hit SSF54719, SSF54719, 1 hit |
PROSITEi | View protein in PROSITE PS00088, SOD_MN, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9Y8H8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVSFKRYELP PLPYNYNALE PYIIEEIMKL HHQKHHNTYV KGANAALEKI
60 70 80 90 100
EKHLKGEIQI DVRAVMRDFS FNYAGHIMHT IFWPNMAPPG KGGGTPGGRV
110 120 130 140 150
ADLIEKQFGG FEKFKALFSA AAKTVEGVGW GVLAFDPLTE ELRILQVEKH
160 170 180 190 200
NVLMTAGLVP ILVIDVWEHA YYLQYKNDRG SYVENWWNVV NWDDVEKRLE
210
QALNNAKPLY LLPQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012621 Genomic DNA Translation: BAA76442.1 BA000002 Genomic DNA Translation: BAA79718.1 |
PIRi | F72664 |
Genome annotation databases
EnsemblBacteriai | BAA79718; BAA79718; APE_0741 |
KEGGi | ape:APE_0741 |
PATRICi | fig|272557.25.peg.534 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012621 Genomic DNA Translation: BAA76442.1 BA000002 Genomic DNA Translation: BAA79718.1 |
PIRi | F72664 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3AK1 | X-ray | 1.57 | A/B/C/D | 1-214 | [»] | |
3AK2 | X-ray | 1.35 | A/B/C/D | 1-214 | [»] | |
3AK3 | X-ray | 1.48 | A/B/C/D | 1-214 | [»] | |
SMRi | Q9Y8H8 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
MINTi | Q9Y8H8 |
STRINGi | 272557.APE_0741 |
Genome annotation databases
EnsemblBacteriai | BAA79718; BAA79718; APE_0741 |
KEGGi | ape:APE_0741 |
PATRICi | fig|272557.25.peg.534 |
Phylogenomic databases
eggNOGi | arCOG04147, Archaea |
OMAi | KWGSFDK |
Enzyme and pathway databases
BRENDAi | 1.15.1.1, 171 |
Miscellaneous databases
EvolutionaryTracei | Q9Y8H8 |
Family and domain databases
Gene3Di | 1.10.287.990, 1 hit 2.40.500.20, 1 hit |
InterProi | View protein in InterPro IPR001189, Mn/Fe_SOD IPR019833, Mn/Fe_SOD_BS IPR019832, Mn/Fe_SOD_C IPR019831, Mn/Fe_SOD_N IPR036324, Mn/Fe_SOD_N_sf IPR036314, SOD_C_sf |
Pfami | View protein in Pfam PF02777, Sod_Fe_C, 1 hit PF00081, Sod_Fe_N, 1 hit |
PIRSFi | PIRSF000349, SODismutase, 1 hit |
PRINTSi | PR01703, MNSODISMTASE |
SUPFAMi | SSF46609, SSF46609, 1 hit SSF54719, SSF54719, 1 hit |
PROSITEi | View protein in PROSITE PS00088, SOD_MN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SODF_AERPE | |
Accessioni | Q9Y8H8Primary (citable) accession number: Q9Y8H8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 2000 |
Last sequence update: | November 1, 1999 | |
Last modified: | April 7, 2021 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families