UniProtKB - Q9Y871 (FAEB_PIREQ)
Protein
Feruloyl esterase B
Gene
ESTA
Organism
Piromyces equi
Status
Functioni
Involved in degradation of plant cell walls. Hydrolyzes of the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.1 Publication
Catalytic activityi
- Feruloyl-polysaccharide + H(2)O = ferulate + polysaccharide. EC:3.1.1.73
Activity regulationi
Inhibited by the specific serine esterase inhibitor AEBSF.
GO - Molecular functioni
- feruloyl esterase activity Source: UniProtKB
GO - Biological processi
- cell wall macromolecule catabolic process Source: UniProtKB
- pectin catabolic process Source: UniProtKB
- xylan catabolic process Source: UniProtKB
Keywordsi
Molecular function | Hydrolase, Serine esterase |
Biological process | Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation |
Enzyme and pathway databases
BRENDAi | 3.1.1.73, 4866 |
Protein family/group databases
CLAEi | FAE1B_PIREQ |
ESTHERi | pireq-faeb, Esterase_phb |
Names & Taxonomyi
Protein namesi | Recommended name: Feruloyl esterase B (EC:3.1.1.73)Alternative name(s): Cinnamoyl ester hydrolase Esterase A Short name: EstA Ferulic acid esterase B |
Gene namesi | Name:ESTA |
Organismi | Piromyces equi |
Taxonomic identifieri | 99929 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Fungi incertae sedis › Chytridiomycota › Chytridiomycota incertae sedis › Neocallimastigomycetes › Neocallimastigales › Neocallimastigaceae › Piromyces |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 20 | Sequence analysisAdd BLAST | 20 | |
ChainiPRO_0000021230 | 21 – 536 | Feruloyl esterase BAdd BLAST | 516 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 65 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinInteractioni
Subunit structurei
Component of the multienzyme cellulase-hemicellulase complex.
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 59 | CBM10PROSITE-ProRule annotationAdd BLAST | 39 | |
Repeati | 78 – 90 | 1Add BLAST | 13 | |
Repeati | 91 – 103 | 2Add BLAST | 13 | |
Repeati | 104 – 116 | 3Add BLAST | 13 | |
Repeati | 117 – 129 | 4Add BLAST | 13 | |
Repeati | 134 – 146 | 5Add BLAST | 13 | |
Repeati | 151 – 163 | 6Add BLAST | 13 | |
Repeati | 164 – 176 | 7Add BLAST | 13 | |
Repeati | 181 – 193 | 8Add BLAST | 13 | |
Repeati | 194 – 206 | 9Add BLAST | 13 | |
Repeati | 211 – 223 | 10Add BLAST | 13 | |
Repeati | 224 – 236 | 11Add BLAST | 13 | |
Repeati | 237 – 249 | 12Add BLAST | 13 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 22 – 59 | Cellulose-bindingAdd BLAST | 38 | |
Regioni | 78 – 249 | 12 X 13 AA repeats of N-Q-G-G-G-M-[PQ]-W-G-D-F-G-GAdd BLAST | 172 | |
Regioni | 257 – 536 | CatalyticAdd BLAST | 280 |
Keywords - Domaini
Repeat, SignalFamily and domain databases
Gene3Di | 3.40.50.1820, 1 hit 3.90.1220.10, 1 hit |
InterProi | View protein in InterPro IPR029058, AB_hydrolase IPR002883, CBM10/Dockerin_dom IPR009034, Dockerin_dom_fun_sf IPR010126, Esterase_phb IPR043595, FaeB/C/D |
PANTHERi | PTHR38050, PTHR38050, 1 hit |
Pfami | View protein in Pfam PF02013, CBM_10, 1 hit PF10503, Esterase_PHB, 1 hit |
SUPFAMi | SSF53474, SSF53474, 1 hit SSF64571, SSF64571, 1 hit |
PROSITEi | View protein in PROSITE PS51763, CBM10, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9Y871-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTSIVLSIV ALFLTSKASA DCWSERLGWP CCSDSNAEVI YVDDDGDWGV
60 70 80 90 100
ENNDWCGIQK EEENNNSWDM GDWNQGGNQG GGMPWGDFGG NQGGGMQWGD
110 120 130 140 150
FGGNQGGGMP WGDFGGNQGG GMPWGDFGGN QGGNQGGGMP WGDFGGNQGG
160 170 180 190 200
NQGGGMPWGD FGGNQGGGMQ WGDFGGNQGG NQGGGMPWGD FGGNQGGGMQ
210 220 230 240 250
WGDFGGNQGG NQGGGMPWGD FGGNQGGGMQ WGDFGGNQGG GMQWGDFGGN
260 270 280 290 300
QGGNQDWGNQ GGNSGPTVEY STDVDCSGKT LKSNTNLNIN GRKVIVKFPS
310 320 330 340 350
GFTGDKAAPL LINYHPIMGS ASQWESGSQT AKAALNDGAI VAFMDGAQGP
360 370 380 390 400
MGQAWNVGPC CTDADDVQFT RNFIKEITSK ACVDPKRIYA AGFSMGGGMS
410 420 430 440 450
NYAGCQLADV IAAAAPSAFD LAKEIVDGGK CKPARPFPIL NFRGTQDNVV
460 470 480 490 500
MYNGGLSQVV QGKPITFMGA KNNFKEWAKM NGCTGEPKQN TPGNNCEMYE
510 520 530
NCKGGVKVGL CTINGGGHAE GDGKMGWDFV KQFSLP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF164516 mRNA Translation: AAD45376.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF164516 mRNA Translation: AAD45376.1 |
3D structure databases
SMRi | Q9Y871 |
ModBasei | Search... |
Protein family/group databases
CLAEi | FAE1B_PIREQ |
ESTHERi | pireq-faeb, Esterase_phb |
Enzyme and pathway databases
BRENDAi | 3.1.1.73, 4866 |
Family and domain databases
Gene3Di | 3.40.50.1820, 1 hit 3.90.1220.10, 1 hit |
InterProi | View protein in InterPro IPR029058, AB_hydrolase IPR002883, CBM10/Dockerin_dom IPR009034, Dockerin_dom_fun_sf IPR010126, Esterase_phb IPR043595, FaeB/C/D |
PANTHERi | PTHR38050, PTHR38050, 1 hit |
Pfami | View protein in Pfam PF02013, CBM_10, 1 hit PF10503, Esterase_PHB, 1 hit |
SUPFAMi | SSF53474, SSF53474, 1 hit SSF64571, SSF64571, 1 hit |
PROSITEi | View protein in PROSITE PS51763, CBM10, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FAEB_PIREQ | |
Accessioni | Q9Y871Primary (citable) accession number: Q9Y871 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 10, 2002 |
Last sequence update: | November 1, 1999 | |
Last modified: | February 10, 2021 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |