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Entry version 150 (11 Dec 2019)
Sequence version 2 (06 Dec 2002)
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Protein

Serine/threonine-protein kinase tor2

Gene

tor2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Phosphatidylinositol 3-kinase homolog, component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC1 controls the switch between cell proliferation and differentiation by sensing nutrient availability. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression (PubMed:17121544, PubMed:17179073, PubMed:17261596). In nutrient rich conditions, responsible for the phosphorylation of AGC S6 kinase (S6K) psk1 at 'Thr-392' and 'Thr-415', activating psk1 kinase activity and promoting phosphorylation of ribosomal protein S6. Also catalyzes the nutrient-dependent phosphorylation of sck1 and sck2 (PubMed:20144990, PubMed:22976295). TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2 (PubMed:17046992).6 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processCell cycle, Meiosis, Sporulation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.1.137 5613

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-1257604 PIP3 activates AKT signaling
R-SPO-3371571 HSF1-dependent transactivation
R-SPO-389357 CD28 dependent PI3K/Akt signaling
R-SPO-5218920 VEGFR2 mediated vascular permeability
R-SPO-6804757 Regulation of TP53 Degradation
R-SPO-9639288 Amino acids regulate mTORC1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine/threonine-protein kinase tor21 Publication (EC:2.7.11.11 Publication)
Alternative name(s):
Phosphatidylinositol kinase homolog tor2
Target of rapamycin kinase 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tor21 Publication
ORF Names:SPBC216.07cImported, SPBC646.01c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPBC216.07c

Schizosaccharomyces pombe database

More...
PomBasei
SPBC216.07c tor2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000888141 – 2337Serine/threonine-protein kinase tor2Add BLAST2337

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1539Phosphoserine1 Publication1
Modified residuei2238Phosphoserine1 Publication1
Modified residuei2240Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y7K2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y7K2

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y7K2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y7K2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The target of rapamycin complex 1 (TORC1) is composed of at least mip1, pop3/wat1, tco89, toc1 and tor2 (PubMed:17046992, PubMed:18076573, PubMed:17261596). Tor2 interacts with the small GTPase rhb1 (PubMed:17121544). Tor2 interacts with ste11 and mei2 (PubMed:17046992).

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q9P3W53EBI-2014299,EBI-2014377

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
277243, 54 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y7K2, 7 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPBC216.07c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y7K2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati163 – 200HEAT 1Add BLAST38
Repeati249 – 286HEAT 2Add BLAST38
Repeati290 – 326HEAT 3Add BLAST37
Repeati409 – 446HEAT 4Add BLAST38
Repeati474 – 512HEAT 5Add BLAST39
Repeati559 – 596HEAT 6Add BLAST38
Repeati642 – 679HEAT 7Add BLAST38
Repeati683 – 721HEAT 8Add BLAST39
Repeati727 – 765HEAT 9Add BLAST39
Repeati802 – 840HEAT 10Add BLAST39
Repeati844 – 880HEAT 11Add BLAST37
Repeati881 – 921HEAT 12Add BLAST41
Repeati965 – 1004HEAT 13Add BLAST40
Repeati1006 – 1043HEAT 14Add BLAST38
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1228 – 1784FATPROSITE-ProRule annotationAdd BLAST557
Domaini1990 – 2304PI3K/PI4KPROSITE-ProRule annotationAdd BLAST315
Domaini2305 – 2337FATCPROSITE-ProRule annotationAdd BLAST33

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000163215

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y7K2

KEGG Orthology (KO)

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KOi
K07203

Identification of Orthologs from Complete Genome Data

More...
OMAi
LNIQRYP

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y7K2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1070.11, 1 hit
1.20.120.150, 1 hit
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024585 DUF3385_TOR
IPR003152 FATC_dom
IPR009076 FRB_dom
IPR036738 FRB_sf
IPR000357 HEAT
IPR021133 HEAT_type_2
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR026683 TOR

The PANTHER Classification System

More...
PANTHERi
PTHR11139:SF9 PTHR11139:SF9, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF11865 DUF3385, 1 hit
PF02259 FAT, 1 hit
PF02260 FATC, 1 hit
PF08771 FRB_dom, 1 hit
PF02985 HEAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01346 DUF3385, 1 hit
SM01343 FATC, 1 hit
SM00146 PI3Kc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47212 SSF47212, 1 hit
SSF48371 SSF48371, 2 hits
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51189 FAT, 1 hit
PS51190 FATC, 1 hit
PS50077 HEAT_REPEAT, 1 hit
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9Y7K2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKEFPGLKSR NEEIRNKAAN DLYEYVIAYS RELSGEALVQ FNNDVNKYVY
60 70 80 90 100
TLIHSTDPLD RLAGVTAINR LIDYEGEDTT RITRFANYLR IILPGTDQKA
110 120 130 140 150
TVLAAKALGR LAVPGGALTS EFVNFEVKRA LEWLQGERNE NRRYAAVLIL
160 170 180 190 200
KELAKNTSTL IYAHIDSIFE LLWHGLRDPK VTIRIASADA LSEFLKIVRQ
210 220 230 240 250
RDSSIRLQWY TSILNEAQRG VAQGSSDYIH GSLLVYRQLF LKAGMFMHER
260 270 280 290 300
YREVSDIILQ FRDHKDLLIR KTVTELIATL AAYNPDEFVS NYLHVCMLHL
310 320 330 340 350
LNLLKKENVK MLAFATIGKV AVAITNSIIP YLDPICDSIK ESLKIHIRNK
360 370 380 390 400
SASDAAIFQC ISLLSIALGQ AFSNYAYDLF DLIFASGLSE ASYRALSDLA
410 420 430 440 450
HNIPPLLPVI QERLLDMLSK ILSGRPFIPP GCPPQYVARS LKSSKSASLK
460 470 480 490 500
TGFFPNDVYI LALKVLGNFD FSGYILNEFV KDCVVVYLEN NDPEVRKTAS
510 520 530 540 550
ITCSQLFARD PILSQTSDHA IQVVAEVLEK LLTVGICDTV PDIRLTVLNS
560 570 580 590 600
LDSRFNKHLA QADKIRLLFI AINDENFAVR ESALRIIGRL NVYNPAYVMP
610 620 630 640 650
YLRKIMLKTL TILDYSTIIR TKEENAKLLC LLIAAAPRLI ESHVEPILQI
660 670 680 690 700
LLPKAKDSSS IVAASIVNSL GEICQISGEV IVPFIKDLMP LIIEALQDQS
710 720 730 740 750
SPIRRAAALK ALGNLSSSTG YVIDPYIEFP SLLDILIGIT KTEQDITIRR
760 770 780 790 800
ETIKLIGTLG ALDPNRHRVL EKGTEKVVPE QKNIPPDISL LMSGIGPSSD
810 820 830 840 850
EYYPTVVITA LMSILKDPSL TIHHTAVIQA VMYIFKTMGL RCAPFLSQII
860 870 880 890 900
PEFIAVMRTC PTNILEFYFQ QLSILVLIVR QHIRSFLPDL FKLIKDFWNP
910 920 930 940 950
HSNLQFTILS LIESLARAMQ GEFKPYLPSL LVMMLQIFDS DVSVDSVSTK
960 970 980 990 1000
KVLHAFIVFG DTLADYFHML LDPILRLYER NDVSIGIKES IMITIGRLSM
1010 1020 1030 1040 1050
VINLSEYASR IIHPVMRMLS CNNASLIRVS MDTVCALIYQ LNVDFAIFIP
1060 1070 1080 1090 1100
MIDKCLKMNG VTHETYSILV EQFLQEQPLP IKLNPYEKYD KPKLDVVASA
1110 1120 1130 1140 1150
ADITSKKLPV NQEILRNAWE ASQRSTKDDW QEWIRRLGVA LLRESPSHAL
1160 1170 1180 1190 1200
RACAALAAAY QPLARDLFNA SFVSCWSELY DHFQEELVKS IEIALTSPHI
1210 1220 1230 1240 1250
SPEIIQILLN LAEFMEHDDK PLPIDIRTLG AYAAKCHAFA KALHYKELEF
1260 1270 1280 1290 1300
IEEELVTKPS VDTIEALISI NNQLQQPDAA IGILKHAQQH DKMNLKETWY
1310 1320 1330 1340 1350
EKLQRWEDAL SAYEKREAAG AGNFEITMGK LRCLHALGEW DRLSQLAQEN
1360 1370 1380 1390 1400
WIHAGHDARR YIAPLSVAAA WGLGQWEQMD EYISVMKSES PDKAFFNAIV
1410 1420 1430 1440 1450
ALHRSQFEEA ASYITRARDL LDTELTALVG ESYNRAYSVA VRVQMLSELE
1460 1470 1480 1490 1500
EIITYKKAED KPEVREMIKK TWVRRLKGCQ RNVDVWQRML RIRSLVISPR
1510 1520 1530 1540 1550
DNMEMWIKFA NLCRKSGRIS LAKKSLNLLL EDDENLDNSL VLKKTHPSIV
1560 1570 1580 1590 1600
YANLKFLWAV DDKRKALNSM QEFTSQLISD INVDPALFVQ STSVNTQKSQ
1610 1620 1630 1640 1650
EEIQYYFHLL ARCYHKQGQW QQEIENNWSE GSFDGVLQSY MYATQFDSKW
1660 1670 1680 1690 1700
YKAWHSWALA NFEAVKFLEQ SEEQIPSAAY EQYIIPAVKG FFKSIALSKG
1710 1720 1730 1740 1750
NLQDTLRLLN LWFKFGNNSN VINTLNVGIS TVNIDIWLDV IPQLIARIHA
1760 1770 1780 1790 1800
SSLSVRKSVH QLLSDVGRAH PQALVYPLTV AAKSQSSARQ NAALAIMDSL
1810 1820 1830 1840 1850
KTHSPRLVEQ ARLVSHELIR AAILWHEQWH EGLEEASRLY FGDHNIEGMF
1860 1870 1880 1890 1900
AVLRPLHEML ERGPETLREI SFQQAFGRDL VEARDCCIRF EQTGDISDLN
1910 1920 1930 1940 1950
QAWDLYYQVF KKIRKQLPQL TTLDLQYVSP KLLHVHDLEL AVPGTYVSGK
1960 1970 1980 1990 2000
PVIRIVKFYP TFNVITSKQR PRRLSIKGSD GKDYQYVLKG HEDIRQDERV
2010 2020 2030 2040 2050
MQLFGLCNNL LLADPETFKR LLSIQRYPVI PLSPDSGLLG WVLDSDTLHV
2060 2070 2080 2090 2100
LIRDYRESRK ILLNIEHRLI IQMAPDYDRL TLLQKVEVFE YALLSTTGQD
2110 2120 2130 2140 2150
LYRVLWLKSR SSEAWLNRRT NYSRTLAVMS MVGYILGLGD RHPSNLMLDR
2160 2170 2180 2190 2200
YTGNIIHIDF GDCFEVAMHR EKFPEKIPFR LTRMLVNAME VSGIEGTFRI
2210 2220 2230 2240 2250
TCEHVMRVLR TNKESVMAVL EAFVYDPLIN WRLAPAYSPS IDEKQSNEPN
2260 2270 2280 2290 2300
TLLGETIDGL HRKRLNEEGI TLEERQKPEI LNQRAITVLN RVSNKLTGRD
2310 2320 2330
FKPQQQLDVP SQVEKLILQA TSIENLCLCY IGWCSFW
Length:2,337
Mass (Da):266,379
Last modified:December 6, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i190F448DA04FD2D9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB40167.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T39913 T40577

NCBI Reference Sequences

More...
RefSeqi
NP_595359.2, NM_001021266.3

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPBC216.07c.1; SPBC216.07c.1:pep; SPBC216.07c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2540720

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPBC216.07c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB40167.1
PIRiT39913 T40577
RefSeqiNP_595359.2, NM_001021266.3

3D structure databases

SMRiQ9Y7K2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi277243, 54 interactors
IntActiQ9Y7K2, 7 interactors
STRINGi4896.SPBC216.07c.1

PTM databases

iPTMnetiQ9Y7K2

Proteomic databases

MaxQBiQ9Y7K2
PaxDbiQ9Y7K2
PRIDEiQ9Y7K2

Genome annotation databases

EnsemblFungiiSPBC216.07c.1; SPBC216.07c.1:pep; SPBC216.07c
GeneIDi2540720
KEGGispo:SPBC216.07c

Organism-specific databases

EuPathDBiFungiDB:SPBC216.07c
PomBaseiSPBC216.07c tor2

Phylogenomic databases

HOGENOMiHOG000163215
InParanoidiQ9Y7K2
KOiK07203
OMAiLNIQRYP
PhylomeDBiQ9Y7K2

Enzyme and pathway databases

BRENDAi2.7.1.137 5613
ReactomeiR-SPO-1257604 PIP3 activates AKT signaling
R-SPO-3371571 HSF1-dependent transactivation
R-SPO-389357 CD28 dependent PI3K/Akt signaling
R-SPO-5218920 VEGFR2 mediated vascular permeability
R-SPO-6804757 Regulation of TP53 Degradation
R-SPO-9639288 Amino acids regulate mTORC1

Miscellaneous databases

Protein Ontology

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PROi
PR:Q9Y7K2

Family and domain databases

Gene3Di1.10.1070.11, 1 hit
1.20.120.150, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024585 DUF3385_TOR
IPR003152 FATC_dom
IPR009076 FRB_dom
IPR036738 FRB_sf
IPR000357 HEAT
IPR021133 HEAT_type_2
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR026683 TOR
PANTHERiPTHR11139:SF9 PTHR11139:SF9, 1 hit
PfamiView protein in Pfam
PF11865 DUF3385, 1 hit
PF02259 FAT, 1 hit
PF02260 FATC, 1 hit
PF08771 FRB_dom, 1 hit
PF02985 HEAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit
SMARTiView protein in SMART
SM01346 DUF3385, 1 hit
SM01343 FATC, 1 hit
SM00146 PI3Kc, 1 hit
SUPFAMiSSF47212 SSF47212, 1 hit
SSF48371 SSF48371, 2 hits
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51189 FAT, 1 hit
PS51190 FATC, 1 hit
PS50077 HEAT_REPEAT, 1 hit
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTOR2_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y7K2
Secondary accession number(s): O94507
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: December 6, 2002
Last modified: December 11, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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