Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative uncharacterized protein AFDN-DT

Gene

AFDN-DT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Product of a dubious CDS prediction. May be a long non-coding RNA.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Putative uncharacterized protein AFDN-DTCurated
Alternative name(s):
AFDN divergent transcriptImported
Protein HGC6.4
Gene namesi
Name:AFDN-DTImported
Synonyms:AFDN-AS1Imported, C6orf124
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:21236 AFDN-DT
neXtProtiNX_Q9Y6Z5

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003321561 – 254Putative uncharacterized protein AFDN-DTAdd BLAST254

Proteomic databases

PRIDEiQ9Y6Z5
ProteomicsDBi86834
86835 [Q9Y6Z5-2]

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

CleanExiHS_C6orf124

Structurei

3D structure databases

ProteinModelPortaliQ9Y6Z5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati22 – 2716
Repeati91 – 9626
Repeati126 – 13136
Repeati174 – 17946

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni22 – 1794 X 5 AA repeat of A-G-S-K-W-[VAG]Add BLAST158

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 185Gly-richAdd BLAST184

Keywords - Domaini

Repeat

Phylogenomic databases

HOVERGENiHBG104047
PhylomeDBiQ9Y6Z5

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9Y6Z5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGAAGSDGRC CVRSGRAGTG GAGSKWVVMD LWTGGAGSRR AVLGPDGRWV
60 70 80 90 100
RWAVLGSVRM GGARSKWAAP DPMGGAGFGP DWRVRVWTGG AGSKWGCSAG
110 120 130 140 150
SGRAVLGPNG RWVPWAVLGS VRTGGAGSKW AALGPMGGTG SGRAVLGLDG
160 170 180 190 200
RCSIQMGAAG SGRAVLGSVR TGGAGSKWAV LGSAGDRWAW RHRYGAQGRW
210 220 230 240 250
SALSEGPCAP RARCSSCPRI APGLLRVSSR VIPFRWVTSK PTFSSCFLPR

RTRC
Length:254
Mass (Da):26,128
Last modified:November 1, 1999 - v1
Checksum:i7B8E0C7110B1E1C5
GO
Isoform 2 (identifier: Q9Y6Z5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     19-32: Missing.

Note: No experimental confirmation available.
Show »
Length:240
Mass (Da):24,639
Checksum:iE47BD0142372E959
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_03335019 – 32Missing in isoform 2. 1 PublicationAdd BLAST14

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB016898 mRNA Translation: BAA78633.1
AK091690 mRNA Translation: BAC03721.1
AK301419 mRNA Translation: BAG62948.1
AL009178 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47487.1
UniGeneiHs.520556

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB016898 mRNA Translation: BAA78633.1
AK091690 mRNA Translation: BAC03721.1
AK301419 mRNA Translation: BAG62948.1
AL009178 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47487.1
UniGeneiHs.520556

3D structure databases

ProteinModelPortaliQ9Y6Z5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ9Y6Z5
ProteomicsDBi86834
86835 [Q9Y6Z5-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiAFDN-DT
HGNCiHGNC:21236 AFDN-DT
neXtProtiNX_Q9Y6Z5
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG104047
PhylomeDBiQ9Y6Z5

Miscellaneous databases

ChiTaRSiAFDN-AS1 human

Gene expression databases

CleanExiHS_C6orf124

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiAFDDT_HUMAN
AccessioniPrimary (citable) accession number: Q9Y6Z5
Secondary accession number(s): B4DW86, Q8NB23
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: November 1, 1999
Last modified: November 7, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again