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Entry version 116 (13 Feb 2019)
Sequence version 2 (26 Feb 2008)
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Protein

Soluble lamin-associated protein of 75 kDa

Gene

FAM169A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Soluble lamin-associated protein of 75 kDa
Short name:
SLAP75
Alternative name(s):
Protein FAM169A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM169A
Synonyms:KIAA0888
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198780.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29138 FAM169A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615769 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y6X4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000198780

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162387117

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM169A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189031482

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003205871 – 670Soluble lamin-associated protein of 75 kDaAdd BLAST670

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei350PhosphoserineBy similarity1
Modified residuei379PhosphoserineBy similarity1
Modified residuei449PhosphoserineCombined sources1
Modified residuei515PhosphoserineBy similarity1
Modified residuei615PhosphoserineBy similarity1
Modified residuei618PhosphoserineBy similarity1
Modified residuei635PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y6X4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y6X4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y6X4

PeptideAtlas

More...
PeptideAtlasi
Q9Y6X4

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y6X4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86814
86815 [Q9Y6X4-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y6X4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y6X4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198780 Expressed in 172 organ(s), highest expression level in caput epididymis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y6X4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y6X4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041574

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117512, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y6X4, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000373808

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Y6X4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y6X4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi377 – 455Asp/Glu-richAdd BLAST79

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM169 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IK9K Eukaryota
ENOG410ZN43 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000048902

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112443

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG107873

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y6X4

Identification of Orthologs from Complete Genome Data

More...
OMAi
KKAHFGS

Database of Orthologous Groups

More...
OrthoDBi
1122654at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y6X4

TreeFam database of animal gene trees

More...
TreeFami
TF332578

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029625 FAM169
IPR029623 FAM169A

The PANTHER Classification System

More...
PANTHERi
PTHR22442 PTHR22442, 1 hit
PTHR22442:SF3 PTHR22442:SF3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y6X4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAFPVDMLEN CSHEELENSA EDYMSDLRCG DPENPECFSL LNITIPISLS
60 70 80 90 100
NVGFVPLYGG DQTQKILALF APEDSLTAVA LYLADQWWAI DDIVKTSVPS
110 120 130 140 150
REGLKQVSTL GERVVLYVLN RIIYRKQEME RNEIPFLCHS STDYAKILWK
160 170 180 190 200
KGEAIGFYSV KPTGSICASF LTQSYQLPVL DTMFLRKKYR GKDFGLHMLE
210 220 230 240 250
DFVDSFTEDA LGLRYPLSSL MYTACKQYFE KYPGDHELLW EVEGVGHWYQ
260 270 280 290 300
RIPVTRALQR EALKILALSQ NEPKRPMSGE YGPASVPEYE ARTEDNQSSE
310 320 330 340 350
MQLTIDSLKD AFASTSEGHD KTSVSTHTRS GNLKRPKIGK RFQDSEFSSS
360 370 380 390 400
QGEDEKTSQT SLTASINKLE STARPSESSE EFLEEEPEQR GIEFEDESSD
410 420 430 440 450
RDARPALETQ PQQEKQDGEK ESELEPMNGE IMDDSLKTSL ITEEEDSTSE
460 470 480 490 500
VLDEELKLQP FNSSEDSTNL VPLVVESSKP PEVDAPDKTP RIPDSEMLMD
510 520 530 540 550
EGTSDEKGHM EEKLSLLPRK KAHLGSSDNV ATMSNEERSD GGFPNSVIAE
560 570 580 590 600
FSEEPVSENL SPNTTSSLED QGEEGVSEPQ ETSTALPQSS LIEVELEDVP
610 620 630 640 650
FSQNAGQKNQ SEEQSEASSE QLDQFTQSAE KAVDSSSEEI EVEVPVVDRR
660 670
NLRRKAKGHK GPAKKKAKLT
Length:670
Mass (Da):74,955
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i735D8883DA82C3F2
GO
Isoform 2 (identifier: Q9Y6X4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     107-127: VSTLGERVVLYVLNRIIYRKQ → EAYVPLFLPKVTNCQFLIQCF
     128-670: Missing.

Note: No experimental confirmation available.
Show »
Length:127
Mass (Da):14,209
Checksum:i0FD56BA3B050262C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6R953D6R953_HUMAN
Soluble lamin-associated protein of...
FAM169A
222Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC41D6RC41_HUMAN
Soluble lamin-associated protein of...
FAM169A
175Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RB01D6RB01_HUMAN
Soluble lamin-associated protein of...
FAM169A
610Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RFI5D6RFI5_HUMAN
Soluble lamin-associated protein of...
FAM169A
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA74911 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAB14344 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAE45948 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti275R → G in BAF82693 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_031670107 – 127VSTLG…IYRKQ → EAYVPLFLPKVTNCQFLIQC F in isoform 2. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_031671128 – 670Missing in isoform 2. 1 PublicationAdd BLAST543

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB020695 mRNA Translation: BAA74911.1 Different initiation.
AK022981 mRNA Translation: BAB14344.1 Different initiation.
AK290004 mRNA Translation: BAF82693.1
BX640902 mRNA Translation: CAE45948.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43330.1 [Q9Y6X4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_056381.1, NM_015566.2 [Q9Y6X4-1]
XP_005248537.1, XM_005248480.2 [Q9Y6X4-1]
XP_011541608.1, XM_011543306.2 [Q9Y6X4-1]
XP_011541609.1, XM_011543307.2 [Q9Y6X4-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.91662

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000389156; ENSP00000373808; ENSG00000198780 [Q9Y6X4-1]
ENST00000510609; ENSP00000423905; ENSG00000198780 [Q9Y6X4-2]
ENST00000514215; ENSP00000425319; ENSG00000198780 [Q9Y6X4-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26049

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26049

UCSC genome browser

More...
UCSCi
uc003kdm.4 human [Q9Y6X4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020695 mRNA Translation: BAA74911.1 Different initiation.
AK022981 mRNA Translation: BAB14344.1 Different initiation.
AK290004 mRNA Translation: BAF82693.1
BX640902 mRNA Translation: CAE45948.1 Different initiation.
CCDSiCCDS43330.1 [Q9Y6X4-1]
RefSeqiNP_056381.1, NM_015566.2 [Q9Y6X4-1]
XP_005248537.1, XM_005248480.2 [Q9Y6X4-1]
XP_011541608.1, XM_011543306.2 [Q9Y6X4-1]
XP_011541609.1, XM_011543307.2 [Q9Y6X4-1]
UniGeneiHs.91662

3D structure databases

ProteinModelPortaliQ9Y6X4
SMRiQ9Y6X4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117512, 4 interactors
IntActiQ9Y6X4, 5 interactors
STRINGi9606.ENSP00000373808

PTM databases

iPTMnetiQ9Y6X4
PhosphoSitePlusiQ9Y6X4

Polymorphism and mutation databases

BioMutaiFAM169A
DMDMi189031482

Proteomic databases

EPDiQ9Y6X4
jPOSTiQ9Y6X4
PaxDbiQ9Y6X4
PeptideAtlasiQ9Y6X4
PRIDEiQ9Y6X4
ProteomicsDBi86814
86815 [Q9Y6X4-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000389156; ENSP00000373808; ENSG00000198780 [Q9Y6X4-1]
ENST00000510609; ENSP00000423905; ENSG00000198780 [Q9Y6X4-2]
ENST00000514215; ENSP00000425319; ENSG00000198780 [Q9Y6X4-2]
GeneIDi26049
KEGGihsa:26049
UCSCiuc003kdm.4 human [Q9Y6X4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26049
EuPathDBiHostDB:ENSG00000198780.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM169A

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0004952
HGNCiHGNC:29138 FAM169A
HPAiHPA041574
MIMi615769 gene
neXtProtiNX_Q9Y6X4
OpenTargetsiENSG00000198780
PharmGKBiPA162387117

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IK9K Eukaryota
ENOG410ZN43 LUCA
GeneTreeiENSGT00510000048902
HOGENOMiHOG000112443
HOVERGENiHBG107873
InParanoidiQ9Y6X4
OMAiKKAHFGS
OrthoDBi1122654at2759
PhylomeDBiQ9Y6X4
TreeFamiTF332578

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM169A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
26049

Protein Ontology

More...
PROi
PR:Q9Y6X4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198780 Expressed in 172 organ(s), highest expression level in caput epididymis
ExpressionAtlasiQ9Y6X4 baseline and differential
GenevisibleiQ9Y6X4 HS

Family and domain databases

InterProiView protein in InterPro
IPR029625 FAM169
IPR029623 FAM169A
PANTHERiPTHR22442 PTHR22442, 1 hit
PTHR22442:SF3 PTHR22442:SF3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF169A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y6X4
Secondary accession number(s): A8K1T9, Q6MZT0, Q9H989
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: February 13, 2019
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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