UniProtKB - Q9Y6T7 (DGKB_HUMAN)
Protein
Diacylglycerol kinase beta
Gene
DGKB
Organism
Homo sapiens (Human)
Status
Functioni
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:11719522). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol (By similarity). Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation (By similarity).By similarityCurated1 Publication
Does not associate with membranes but has a diacylglycerol kinase activity.1 Publication
Catalytic activityi
- EC:2.7.1.1071 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H+1 PublicationThis reaction proceeds in the forward1 Publication direction.This reaction proceeds in the forward1 Publication direction.This reaction proceeds in the forward1 Publication direction.
- 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+By similarityThis reaction proceeds in the forwardBy similarity direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+By similarityThis reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
Activity regulationi
Activated by calcium.By similarity
: glycerolipid metabolism Pathwayi
This protein is involved in the pathway glycerolipid metabolism, which is part of Lipid metabolism.1 PublicationView all proteins of this organism that are known to be involved in the pathway glycerolipid metabolism and in Lipid metabolism.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 162 – 173 | 1PROSITE-ProRule annotationAdd BLAST | 12 | |
Calcium bindingi | 207 – 218 | 2PROSITE-ProRule annotationAdd BLAST | 12 | |
Zinc fingeri | 244 – 294 | Phorbol-ester/DAG-type 1PROSITE-ProRule annotationAdd BLAST | 51 | |
Zinc fingeri | 309 – 358 | Phorbol-ester/DAG-type 2PROSITE-ProRule annotationAdd BLAST | 50 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- calcium ion binding Source: InterPro
- diacylglycerol kinase activity Source: BHF-UCL
- lipid binding Source: BHF-UCL
- NAD+ kinase activity Source: InterPro
GO - Biological processi
- diacylglycerol metabolic process Source: UniProtKB
- glycerolipid metabolic process Source: BHF-UCL
- intracellular signal transduction Source: GO_Central
- lipid phosphorylation Source: BHF-UCL
- modulation of chemical synaptic transmission Source: Ensembl
- phosphatidic acid biosynthetic process Source: UniProtKB
- platelet activation Source: Reactome
- protein kinase C-activating G protein-coupled receptor signaling pathway Source: InterPro
- regulation of postsynapse organization Source: Ensembl
- response to bacterium Source: Ensembl
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, Calcium, Metal-binding, Nucleotide-binding, Zinc |
Enzyme and pathway databases
BRENDAi | 2.7.1.107, 2681 |
PathwayCommonsi | Q9Y6T7 |
Reactomei | R-HSA-114508, Effects of PIP2 hydrolysis |
SABIO-RKi | Q9Y6T7 |
UniPathwayi | UPA00230 |
Chemistry databases
SwissLipidsi | SLP:000000915 [Q9Y6T7-1] SLP:000000916 [Q9Y6T7-2] |
Names & Taxonomyi
Protein namesi | Recommended name: Diacylglycerol kinase beta (EC:2.7.1.1071 Publication)Short name: DAG kinase beta Alternative name(s): 90 kDa diacylglycerol kinase Diglyceride kinase beta Short name: DGK-beta |
Gene namesi | Name:DGKB Synonyms:DAGK2, KIAA0718 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2850, DGKB |
MIMi | 604070, gene |
neXtProti | NX_Q9Y6T7 |
VEuPathDBi | HostDB:ENSG00000136267.13 |
Subcellular locationi
Plasma membrane
- postsynaptic cell membrane By similarity; Peripheral membrane protein By similarity
- Cell membrane 1 Publication; Peripheral membrane protein 1 Publication
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Note: Translocation to the plasma membrane is induced by phorbol esters.1 Publication
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Cytosol
- cytosol Source: BHF-UCL
Plasma Membrane
- plasma membrane Source: BHF-UCL
- postsynaptic membrane Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-SubCell
- glutamatergic synapse Source: Ensembl
- Schaffer collateral - CA1 synapse Source: Ensembl
Keywords - Cellular componenti
Cell junction, Cell membrane, Cytoplasm, Membrane, Postsynaptic cell membrane, SynapsePathology & Biotechi
Organism-specific databases
DisGeNETi | 1607 |
OpenTargetsi | ENSG00000136267 |
PharmGKBi | PA27311 |
Miscellaneous databases
Pharosi | Q9Y6T7, Tbio |
Chemistry databases
ChEMBLi | CHEMBL4105755 |
DrugBanki | DB14001, alpha-Tocopherol succinate |
Genetic variation databases
BioMutai | DGKB |
DMDMi | 12643960 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000218457 | 1 – 804 | Diacylglycerol kinase betaAdd BLAST | 804 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 117 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 420 | PhosphoserineBy similarity | 1 | |
Modified residuei | 793 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | Q9Y6T7 |
MassIVEi | Q9Y6T7 |
PaxDbi | Q9Y6T7 |
PeptideAtlasi | Q9Y6T7 |
PRIDEi | Q9Y6T7 |
ProteomicsDBi | 86787 [Q9Y6T7-1] 86788 [Q9Y6T7-2] |
PTM databases
iPTMneti | Q9Y6T7 |
PhosphoSitePlusi | Q9Y6T7 |
Expressioni
Tissue specificityi
Specifically expressed in brain but also detected in uterus (PubMed:11719522). In adult brain, expressed in the amygdala, caudate nucleus, and hippocampus (PubMed:11719522).1 Publication
More ubiquitously expressed but at lower level compared to isoform 1.1 Publication
Gene expression databases
Bgeei | ENSG00000136267, Expressed in caudate nucleus and 140 other tissues |
ExpressionAtlasi | Q9Y6T7, baseline and differential |
Genevisiblei | Q9Y6T7, HS |
Organism-specific databases
HPAi | ENSG00000136267, Tissue enriched (brain) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 107977, 2 interactors |
STRINGi | 9606.ENSP00000385780 |
Chemistry databases
BindingDBi | Q9Y6T7 |
Miscellaneous databases
RNActi | Q9Y6T7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 149 – 184 | EF-hand 1PROSITE-ProRule annotationAdd BLAST | 36 | |
Domaini | 194 – 229 | EF-hand 2PROSITE-ProRule annotationAdd BLAST | 36 | |
Domaini | 434 – 568 | DAGKcPROSITE-ProRule annotationAdd BLAST | 135 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 771 – 804 | Required for association with membranes and function in neurite spine formation1 PublicationAdd BLAST | 34 |
Sequence similaritiesi
Belongs to the eukaryotic diacylglycerol kinase family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 244 – 294 | Phorbol-ester/DAG-type 1PROSITE-ProRule annotationAdd BLAST | 51 | |
Zinc fingeri | 309 – 358 | Phorbol-ester/DAG-type 2PROSITE-ProRule annotationAdd BLAST | 50 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1169, Eukaryota |
GeneTreei | ENSGT00940000159770 |
InParanoidi | Q9Y6T7 |
OMAi | CAPITSH |
OrthoDBi | 633642at2759 |
PhylomeDBi | Q9Y6T7 |
TreeFami | TF313104 |
Family and domain databases
CDDi | cd00029, C1, 2 hits cd00051, EFh, 1 hit |
Gene3Di | 1.10.238.110, 2 hits 3.40.50.10330, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR029477, DAG_kinase_typeI_N IPR037607, DGK IPR038199, DGK_typeI_N_sf IPR000756, Diacylglycerol_kin_accessory IPR001206, Diacylglycerol_kinase_cat_dom IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR016064, NAD/diacylglycerol_kinase_sf IPR002219, PE/DAG-bd |
PANTHERi | PTHR11255, PTHR11255, 1 hit |
Pfami | View protein in Pfam PF00130, C1_1, 2 hits PF14513, DAG_kinase_N, 1 hit PF00609, DAGK_acc, 1 hit PF00781, DAGK_cat, 1 hit PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00109, C1, 2 hits SM00045, DAGKa, 1 hit SM00046, DAGKc, 1 hit SM00054, EFh, 2 hits |
SUPFAMi | SSF111331, SSF111331, 1 hit SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS50146, DAGK, 1 hit PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits PS00479, ZF_DAG_PE_1, 2 hits PS50081, ZF_DAG_PE_2, 2 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q9Y6T7-1) [UniParc]FASTAAdd to basket
Also known as: STD1 Publication
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MTNQEKWAHL SPSEFSQLQK YAEYSTKKLK DVLEEFHGNG VLAKYNPEGK
60 70 80 90 100
QDILNQTIDF EGFKLFMKTF LEAELPDDFT AHLFMSFSNK FPHSSPMVKS
110 120 130 140 150
KPALLSGGLR MNKGAITPPR TTSPANTCSP EVIHLKDIVC YLSLLERGRP
160 170 180 190 200
EDKLEFMFRL YDTDGNGFLD SSELENIISQ MMHVAEYLEW DVTELNPILH
210 220 230 240 250
EMMEEIDYDH DGTVSLEEWI QGGMTTIPLL VLLGLENNVK DDGQHVWRLK
260 270 280 290 300
HFNKPAYCNL CLNMLIGVGK QGLCCSFCKY TVHERCVARA PPSCIKTYVK
310 320 330 340 350
SKRNTDVMHH YWVEGNCPTK CDKCHKTVKC YQGLTGLHCV WCQITLHNKC
360 370 380 390 400
ASHLKPECDC GPLKDHILPP TTICPVVLQT LPTSGVSVPE ERQSTVKKEK
410 420 430 440 450
SGSQQPNKVI DKNKMQRANS VTVDGQGLQV TPVPGTHPLL VFVNPKSGGK
460 470 480 490 500
QGERIYRKFQ YLLNPRQVYS LSGNGPMPGL NFFRDVPDFR VLACGGDGTV
510 520 530 540 550
GWVLDCIEKA NVGKHPPVAI LPLGTGNDLA RCLRWGGGYE GENLMKILKD
560 570 580 590 600
IENSTEIMLD RWKFEVIPND KDEKGDPVPY SIINNYFSIG VDASIAHRFH
610 620 630 640 650
IMREKHPEKF NSRMKNKFWY FEFGTSETFS ATCKKLHESV EIECDGVQID
660 670 680 690 700
LINISLEGIA ILNIPSMHGG SNLWGESKKR RSHRRIEKKG SDKRTTVTDA
710 720 730 740 750
KELKFASQDL SDQLLEVVGL EGAMEMGQIY TGLKSAGRRL AQCSCVVIRT
760 770 780 790 800
SKSLPMQIDG EPWMQTPCTI KITHKNQAPM LMGPPPKTGL FCSLVKRTRN
RSKE
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB5MCD5 | B5MCD5_HUMAN | Diacylglycerol kinase | DGKB | 796 | Annotation score: | ||
B5MBY2 | B5MBY2_HUMAN | Diacylglycerol kinase | DGKB | 803 | Annotation score: | ||
C9JA18 | C9JA18_HUMAN | Diacylglycerol kinase beta | DGKB | 75 | Annotation score: |
Sequence cautioni
The sequence AAS07533 differs from that shown. Reason: Erroneous gene model prediction.Curated
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_048858 | 789 | G → S. Corresponds to variant dbSNP:rs34616903Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_021898 | 770 – 773 | IKIT → VSTE in isoform 2. 1 Publication | 4 | |
Alternative sequenceiVSP_021899 | 774 – 804 | Missing in isoform 2. 1 PublicationAdd BLAST | 31 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AX032742 mRNA Translation: CAC09945.1 AC005039 Genomic DNA Translation: AAS07495.1 AC005248 Genomic DNA Translation: AAC25525.1 AC006150 Genomic DNA No translation available. AC011229 Genomic DNA Translation: AAP21868.1 AC073258 Genomic DNA Translation: AAS07533.1 Sequence problems. AC105459 Genomic DNA Translation: AAP22362.1 CH236948 Genomic DNA Translation: EAL24292.1 CH236948 Genomic DNA Translation: EAL24293.1 CH471073 Genomic DNA Translation: EAW93663.1 CH471073 Genomic DNA Translation: EAW93664.1 BC105005 mRNA Translation: AAI05006.1 AB018261 mRNA Translation: BAA34438.1 |
CCDSi | CCDS47547.1 [Q9Y6T7-1] CCDS47548.1 [Q9Y6T7-2] |
RefSeqi | NP_004071.1, NM_004080.2 NP_663733.1, NM_145695.2 [Q9Y6T7-2] XP_005249685.1, XM_005249628.2 XP_011513455.1, XM_011515153.2 XP_011513456.1, XM_011515154.2 [Q9Y6T7-1] |
Genome annotation databases
Ensembli | ENST00000399322; ENSP00000382260; ENSG00000136267 [Q9Y6T7-1] ENST00000403951; ENSP00000385780; ENSG00000136267 [Q9Y6T7-1] ENST00000406247; ENSP00000386066; ENSG00000136267 [Q9Y6T7-2] |
GeneIDi | 1607 |
KEGGi | hsa:1607 |
UCSCi | uc003ssz.3, human [Q9Y6T7-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AX032742 mRNA Translation: CAC09945.1 AC005039 Genomic DNA Translation: AAS07495.1 AC005248 Genomic DNA Translation: AAC25525.1 AC006150 Genomic DNA No translation available. AC011229 Genomic DNA Translation: AAP21868.1 AC073258 Genomic DNA Translation: AAS07533.1 Sequence problems. AC105459 Genomic DNA Translation: AAP22362.1 CH236948 Genomic DNA Translation: EAL24292.1 CH236948 Genomic DNA Translation: EAL24293.1 CH471073 Genomic DNA Translation: EAW93663.1 CH471073 Genomic DNA Translation: EAW93664.1 BC105005 mRNA Translation: AAI05006.1 AB018261 mRNA Translation: BAA34438.1 |
CCDSi | CCDS47547.1 [Q9Y6T7-1] CCDS47548.1 [Q9Y6T7-2] |
RefSeqi | NP_004071.1, NM_004080.2 NP_663733.1, NM_145695.2 [Q9Y6T7-2] XP_005249685.1, XM_005249628.2 XP_011513455.1, XM_011515153.2 XP_011513456.1, XM_011515154.2 [Q9Y6T7-1] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 107977, 2 interactors |
STRINGi | 9606.ENSP00000385780 |
Chemistry databases
BindingDBi | Q9Y6T7 |
ChEMBLi | CHEMBL4105755 |
DrugBanki | DB14001, alpha-Tocopherol succinate |
SwissLipidsi | SLP:000000915 [Q9Y6T7-1] SLP:000000916 [Q9Y6T7-2] |
PTM databases
iPTMneti | Q9Y6T7 |
PhosphoSitePlusi | Q9Y6T7 |
Genetic variation databases
BioMutai | DGKB |
DMDMi | 12643960 |
Proteomic databases
jPOSTi | Q9Y6T7 |
MassIVEi | Q9Y6T7 |
PaxDbi | Q9Y6T7 |
PeptideAtlasi | Q9Y6T7 |
PRIDEi | Q9Y6T7 |
ProteomicsDBi | 86787 [Q9Y6T7-1] 86788 [Q9Y6T7-2] |
Protocols and materials databases
Antibodypediai | 25192, 216 antibodies |
DNASUi | 1607 |
Genome annotation databases
Ensembli | ENST00000399322; ENSP00000382260; ENSG00000136267 [Q9Y6T7-1] ENST00000403951; ENSP00000385780; ENSG00000136267 [Q9Y6T7-1] ENST00000406247; ENSP00000386066; ENSG00000136267 [Q9Y6T7-2] |
GeneIDi | 1607 |
KEGGi | hsa:1607 |
UCSCi | uc003ssz.3, human [Q9Y6T7-1] |
Organism-specific databases
CTDi | 1607 |
DisGeNETi | 1607 |
GeneCardsi | DGKB |
HGNCi | HGNC:2850, DGKB |
HPAi | ENSG00000136267, Tissue enriched (brain) |
MIMi | 604070, gene |
neXtProti | NX_Q9Y6T7 |
OpenTargetsi | ENSG00000136267 |
PharmGKBi | PA27311 |
VEuPathDBi | HostDB:ENSG00000136267.13 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1169, Eukaryota |
GeneTreei | ENSGT00940000159770 |
InParanoidi | Q9Y6T7 |
OMAi | CAPITSH |
OrthoDBi | 633642at2759 |
PhylomeDBi | Q9Y6T7 |
TreeFami | TF313104 |
Enzyme and pathway databases
UniPathwayi | UPA00230 |
BRENDAi | 2.7.1.107, 2681 |
PathwayCommonsi | Q9Y6T7 |
Reactomei | R-HSA-114508, Effects of PIP2 hydrolysis |
SABIO-RKi | Q9Y6T7 |
Miscellaneous databases
BioGRID-ORCSi | 1607, 3 hits in 986 CRISPR screens |
ChiTaRSi | DGKB, human |
GeneWikii | DGKB |
GenomeRNAii | 1607 |
Pharosi | Q9Y6T7, Tbio |
PROi | PR:Q9Y6T7 |
RNActi | Q9Y6T7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000136267, Expressed in caudate nucleus and 140 other tissues |
ExpressionAtlasi | Q9Y6T7, baseline and differential |
Genevisiblei | Q9Y6T7, HS |
Family and domain databases
CDDi | cd00029, C1, 2 hits cd00051, EFh, 1 hit |
Gene3Di | 1.10.238.110, 2 hits 3.40.50.10330, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR029477, DAG_kinase_typeI_N IPR037607, DGK IPR038199, DGK_typeI_N_sf IPR000756, Diacylglycerol_kin_accessory IPR001206, Diacylglycerol_kinase_cat_dom IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR016064, NAD/diacylglycerol_kinase_sf IPR002219, PE/DAG-bd |
PANTHERi | PTHR11255, PTHR11255, 1 hit |
Pfami | View protein in Pfam PF00130, C1_1, 2 hits PF14513, DAG_kinase_N, 1 hit PF00609, DAGK_acc, 1 hit PF00781, DAGK_cat, 1 hit PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00109, C1, 2 hits SM00045, DAGKa, 1 hit SM00046, DAGKc, 1 hit SM00054, EFh, 2 hits |
SUPFAMi | SSF111331, SSF111331, 1 hit SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS50146, DAGK, 1 hit PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits PS00479, ZF_DAG_PE_1, 2 hits PS50081, ZF_DAG_PE_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DGKB_HUMAN | |
Accessioni | Q9Y6T7Primary (citable) accession number: Q9Y6T7 Secondary accession number(s): A4D116 Q9UQ29 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | January 11, 2001 | |
Last modified: | April 7, 2021 | |
This is version 188 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families