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Entry version 151 (11 Dec 2019)
Sequence version 1 (01 Nov 1999)
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Protein

Zinc finger protein 780B

Gene

ZNF780B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri165 – 187C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 215C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri221 – 243C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri249 – 271C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri277 – 299C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri333 – 355C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri361 – 383C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri389 – 411C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri417 – 439C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri445 – 467C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri473 – 495C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri501 – 523C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri529 – 551C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri557 – 579C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri585 – 607C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri613 – 635C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri641 – 663C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri669 – 691C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri697 – 719C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri725 – 747C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri753 – 775C2H2-type 22; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri781 – 803C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 780B
Alternative name(s):
Zinc finger protein 779
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF780B
Synonyms:ZNF779
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000128000.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33109 ZNF780B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y6R6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
163131

Open Targets

More...
OpenTargetsi
ENSG00000128000

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410426

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y6R6 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF780B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74762083

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002630881 – 833Zinc finger protein 780BAdd BLAST833

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y6R6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y6R6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y6R6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y6R6

PeptideAtlas

More...
PeptideAtlasi
Q9Y6R6

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y6R6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
86779

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y6R6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y6R6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000128000 Expressed in 152 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y6R6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y6R6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003311

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9Y6R6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000391641

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y6R6 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y6R6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 77KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri165 – 187C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 215C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri221 – 243C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri249 – 271C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri277 – 299C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri333 – 355C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri361 – 383C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri389 – 411C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri417 – 439C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri445 – 467C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri473 – 495C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri501 – 523C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri529 – 551C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri557 – 579C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri585 – 607C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri613 – 635C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri641 – 663C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri669 – 691C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri697 – 719C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri725 – 747C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri753 – 775C2H2-type 22; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri781 – 803C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164600

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y6R6

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
KRPERHF

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y6R6

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 23 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 21 hits
PS50157 ZINC_FINGER_C2H2_2, 23 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q9Y6R6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVHGSVTFRD VAIDFSQEEW ECLQPDQRTL YRDVMLENYS HLISLGSSIS
60 70 80 90 100
KPDVITLLEQ EKEPWIVVSK ETSRWYPDLE SKYGPEKISP ENDIFEINLP
110 120 130 140 150
KHVIKQISKT LGLEAFYFRN DSEYRSRFEG RQGHQEGYIN QKIISYEEMP
160 170 180 190 200
AYTHASPIHN THKPYECKEC GKYFSCGSNL IQHQSIHTGE KPYKCKECGK
210 220 230 240 250
AFQLHIQLTR HQKFHTGEKT FECKECGKAF NLPTQLNRHK NIHTVKKLFE
260 270 280 290 300
CKECGKSFNR SSNLTQHQSI HAGVKPYQCK ECGKAFNRGS NLIQHQKIHS
310 320 330 340 350
NEKPFVCREC EMAFRYHYQL IEHCRIHTGE KPFECKECRK AFTLLTKLVR
360 370 380 390 400
HQKIHMGEKP FECRECGKAF SLLNQLNRHK NIHTGEKPFE CKECGKSFNR
410 420 430 440 450
SSNLIQHQSI HADVKPYECK ECGKGFNRGA NLIQHQKIHS NEKPFVCREC
460 470 480 490 500
EMAFRYHYQL IQHCQIHTGG KPFECKECGK AFSLLTQLAR HKNIHTGEKP
510 520 530 540 550
FECKDCGKAF NRGSNLVQHQ SIHTGEKPYE CKECGKAFRL HLQLSQHEKT
560 570 580 590 600
HTGEKPFECK ECGKFFRRGS NLNQHRSIHT GKKPFECKEC GKAFRLHMHL
610 620 630 640 650
IRHQKFHTGE KPFECKECGK AFSLHTQLNH HKNIHTGEKP FKCKECGKSF
660 670 680 690 700
NRVSNLVQHQ SIHAGVKPYE CKECGKGFSR VSNLIQHQKT HSSAKPFVCK
710 720 730 740 750
ECRKTFRYHY QLTEHYRIHT GEKPFECKEC GKAFGLLTQL AQHQIIHTGE
760 770 780 790 800
KPFKCKECGK AFNRGSNLVQ PQSIHTGEKP YECKECGKAF RLHLQLSLHQ
810 820 830
KLVQVRNPLN VRNVGQPSDI SSNLLNIRKF ILG
Length:833
Mass (Da):96,807
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2A354BA8B633B54A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JTJ1C9JTJ1_HUMAN
Hypothetical BC331191_1, isoform CR...
ZNF780B LOC163131, hCG_43358
685Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B7A7A0A075B7A7_HUMAN
Zinc finger protein 780B
ZNF780B
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0W9M0R0W9_HUMAN
Zinc finger protein 780B
ZNF780B
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R168M0R168_HUMAN
Zinc finger protein 780B
ZNF780B
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007842 Genomic DNA Translation: AAD39268.1
CH471126 Genomic DNA Translation: EAW56932.1
BC136960 mRNA Translation: AAI36961.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46077.1

NCBI Reference Sequences

More...
RefSeqi
NP_001005851.1, NM_001005851.2
XP_005258650.1, XM_005258593.2
XP_016881914.1, XM_017026425.1
XP_016881915.1, XM_017026426.1
XP_016881916.1, XM_017026427.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000434248; ENSP00000391641; ENSG00000128000
ENST00000617676; ENSP00000484593; ENSG00000128000
ENST00000625684; ENSP00000487572; ENSG00000281601
ENST00000627167; ENSP00000487499; ENSG00000281601

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
163131

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:163131

UCSC genome browser

More...
UCSCi
uc002omu.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007842 Genomic DNA Translation: AAD39268.1
CH471126 Genomic DNA Translation: EAW56932.1
BC136960 mRNA Translation: AAI36961.1
CCDSiCCDS46077.1
RefSeqiNP_001005851.1, NM_001005851.2
XP_005258650.1, XM_005258593.2
XP_016881914.1, XM_017026425.1
XP_016881915.1, XM_017026426.1
XP_016881916.1, XM_017026427.1

3D structure databases

SMRiQ9Y6R6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9Y6R6, 1 interactor
STRINGi9606.ENSP00000391641

PTM databases

iPTMnetiQ9Y6R6
PhosphoSitePlusiQ9Y6R6

Polymorphism and mutation databases

BioMutaiZNF780B
DMDMi74762083

Proteomic databases

jPOSTiQ9Y6R6
MassIVEiQ9Y6R6
MaxQBiQ9Y6R6
PaxDbiQ9Y6R6
PeptideAtlasiQ9Y6R6
PRIDEiQ9Y6R6
ProteomicsDBi86779

Genome annotation databases

EnsembliENST00000434248; ENSP00000391641; ENSG00000128000
ENST00000617676; ENSP00000484593; ENSG00000128000
ENST00000625684; ENSP00000487572; ENSG00000281601
ENST00000627167; ENSP00000487499; ENSG00000281601
GeneIDi163131
KEGGihsa:163131
UCSCiuc002omu.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
163131
DisGeNETi163131
EuPathDBiHostDB:ENSG00000128000.15

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF780B
HGNCiHGNC:33109 ZNF780B
HPAiHPA003311
neXtProtiNX_Q9Y6R6
OpenTargetsiENSG00000128000
PharmGKBiPA162410426

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000164600
HOGENOMiHOG000234617
InParanoidiQ9Y6R6
KOiK09228
OMAiKRPERHF
OrthoDBi1318335at2759
PhylomeDBiQ9Y6R6
TreeFamiTF343410

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
163131
PharosiQ9Y6R6 Tdark

Protein Ontology

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PROi
PR:Q9Y6R6
RNActiQ9Y6R6 protein

Gene expression databases

BgeeiENSG00000128000 Expressed in 152 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ9Y6R6 baseline and differential
GenevisibleiQ9Y6R6 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 13 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 23 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 21 hits
PS50157 ZINC_FINGER_C2H2_2, 23 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZ780B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y6R6
Secondary accession number(s): B9EH00
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 1, 1999
Last modified: December 11, 2019
This is version 151 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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