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UniProtKB - Q9Y6H3 (ATP23_HUMAN)

Entry version 127 (07 Oct 2020)
Sequence version 3 (03 Mar 2009)
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Protein

Mitochondrial inner membrane protease ATP23 homolog

Gene

ATP23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi125Divalent metal cation; catalyticBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei126PROSITE-ProRule annotation1
Metal bindingi129Divalent metal cation; catalyticBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Metalloprotease, Protease
LigandMetal-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9Y6H3

Protein family/group databases

MEROPS protease database

More...MEROPSi		M76.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial inner membrane protease ATP23 homolog (EC:3.4.24.-)
Alternative name(s):
Ku70-binding protein 3
XRCC6-binding protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATP23Imported
Synonyms:KUB3, XRCC6BP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000166896.7

Human Gene Nomenclature Database

More...HGNCi		HGNC:29452, ATP23

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y6H3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		91419

Open Targets

More...OpenTargetsi		ENSG00000166896

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670557

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y6H3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ATP23

Domain mapping of disease mutations (DMDM)

More...DMDMi		224471894

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003303441 – 246Mitochondrial inner membrane protease ATP23 homologAdd BLAST246

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y6H3

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y6H3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y6H3

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Y6H3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y6H3

PeptideAtlas

More...PeptideAtlasi		Q9Y6H3

PRoteomics IDEntifications database

More...PRIDEi		Q9Y6H3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		86679

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y6H3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y6H3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000166896, Expressed in right testis and 185 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y6H3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y6H3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000166896, Tissue enhanced (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with XRCC6.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124830, 48 interactors

Protein interaction database and analysis system

More...IntActi		Q9Y6H3, 36 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000300145

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y6H3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y6H3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase M76 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3314, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010948

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_079125_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y6H3

KEGG Orthology (KO)

More...KOi		K18156

Identification of Orthologs from Complete Genome Data

More...OMAi		VDHLACT

Database of Orthologous Groups

More...OrthoDBi		1288109at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y6H3

TreeFam database of animal gene trees

More...TreeFami		TF327014

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019165, Peptidase_M76_ATP23

The PANTHER Classification System

More...PANTHERi		PTHR21711, PTHR21711, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09768, Peptidase_M76, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00142, ZINC_PROTEASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y6H3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ 
        60         70         80         90        100
KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD 
       110        120        130        140        150
ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS 
       160        170        180        190        200
EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV 
       210        220        230        240 
AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI
Length:246
Mass (Da):28,081
Last modified:March 3, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9541CBEA299A35F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YIJ9H0YIJ9_HUMAN
Mitochondrial inner membrane protea...
ATP23
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD31085 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05448948S → C1 PublicationCorresponds to variant dbSNP:rs3751325Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF078164 mRNA Translation: AAD31085.1 Different initiation.
AC084033 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97091.1
BC012776 mRNA Translation: AAH12776.3
BC115381 mRNA Translation: AAI15382.1
BC115382 mRNA Translation: AAI15383.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS41802.1

NCBI Reference Sequences

More...RefSeqi		NP_001307337.1, NM_001320408.1
NP_001307338.1, NM_001320409.1
NP_001307339.1, NM_001320410.1
NP_150592.1, NM_033276.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000300145; ENSP00000300145; ENSG00000166896
ENST00000571490; ENSP00000460944; ENSG00000262145

Database of genes from NCBI RefSeq genomes

More...GeneIDi		91419

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:91419

UCSC genome browser

More...UCSCi		uc001sqp.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF078164 mRNA Translation: AAD31085.1 Different initiation.
AC084033 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97091.1
BC012776 mRNA Translation: AAH12776.3
BC115381 mRNA Translation: AAI15382.1
BC115382 mRNA Translation: AAI15383.1
CCDSiCCDS41802.1
RefSeqiNP_001307337.1, NM_001320408.1
NP_001307338.1, NM_001320409.1
NP_001307339.1, NM_001320410.1
NP_150592.1, NM_033276.3

3D structure databases

SMRiQ9Y6H3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124830, 48 interactors
IntActiQ9Y6H3, 36 interactors
STRINGi9606.ENSP00000300145

Protein family/group databases

MEROPSiM76.001

PTM databases

iPTMnetiQ9Y6H3
PhosphoSitePlusiQ9Y6H3

Polymorphism and mutation databases

BioMutaiATP23
DMDMi224471894

Proteomic databases

EPDiQ9Y6H3
jPOSTiQ9Y6H3
MassIVEiQ9Y6H3
MaxQBiQ9Y6H3
PaxDbiQ9Y6H3
PeptideAtlasiQ9Y6H3
PRIDEiQ9Y6H3
ProteomicsDBi86679

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		28994, 90 antibodies

The DNASU plasmid repository

More...DNASUi		91419

Genome annotation databases

EnsembliENST00000300145; ENSP00000300145; ENSG00000166896
ENST00000571490; ENSP00000460944; ENSG00000262145
GeneIDi91419
KEGGihsa:91419
UCSCiuc001sqp.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		91419
DisGeNETi91419
EuPathDBiHostDB:ENSG00000166896.7

GeneCards: human genes, protein and diseases

More...GeneCardsi		ATP23
HGNCiHGNC:29452, ATP23
HPAiENSG00000166896, Tissue enhanced (testis)
neXtProtiNX_Q9Y6H3
OpenTargetsiENSG00000166896
PharmGKBiPA142670557

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3314, Eukaryota
GeneTreeiENSGT00390000010948
HOGENOMiCLU_079125_1_0_1
InParanoidiQ9Y6H3
KOiK18156
OMAiVDHLACT
OrthoDBi1288109at2759
PhylomeDBiQ9Y6H3
TreeFamiTF327014

Enzyme and pathway databases

PathwayCommonsiQ9Y6H3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		91419, 50 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ATP23, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		91419
PharosiQ9Y6H3, Tdark

Protein Ontology

More...PROi		PR:Q9Y6H3
RNActiQ9Y6H3, protein

Gene expression databases

BgeeiENSG00000166896, Expressed in right testis and 185 other tissues
ExpressionAtlasiQ9Y6H3, baseline and differential
GenevisibleiQ9Y6H3, HS

Family and domain databases

InterProiView protein in InterPro
IPR019165, Peptidase_M76_ATP23
PANTHERiPTHR21711, PTHR21711, 1 hit
PfamiView protein in Pfam
PF09768, Peptidase_M76, 1 hit
PROSITEiView protein in PROSITE
PS00142, ZINC_PROTEASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATP23_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y6H3
Secondary accession number(s): Q1RLM4, Q96E81
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 3, 2009
Last modified: October 7, 2020
This is version 127 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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