UniProtKB - Q9Y6E2 (BZW2_HUMAN)

BLAST

>sp|Q9Y6E2|BZW2_HUMAN Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1
MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLD
YRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIR
RYKYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKE
GIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLK
ELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTC
IMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAF
QKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN

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History
Entry version 140 (10 Oct 2018)
Sequence version 1 (01 Nov 1999)
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Protein

Basic leucine zipper and W2 domain-containing protein 2

Gene

BZW2

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May be involved in neuronal differentiation.By similarity

GO - Molecular functionⁱ

cadherin binding
Source: BHF-UCL
Inferred from high throughput direct assayⁱ
- 25468996

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell differentiation Source: UniProtKB-KW
nervous system development Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental protein
Biological process	Differentiation, Neurogenesis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Basic leucine zipper and W2 domain-containing protein 2
Gene namesⁱ	Name:BZW2 ORF Names:HSPC028, MSTP017
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000136261.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:18808 BZW2
neXtProtⁱ	NX_Q9Y6E2

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	28969
Open Targets More...OpenTargetsⁱ	ENSG00000136261
PharmGKBⁱ	PA38690

Polymorphism and mutation databases

BioMutaⁱ	BZW2
DMDMⁱ	74762077

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000254618	1 – 419	Basic leucine zipper and W2 domain-containing protein 2Add BLAST		419

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	117	N6-acetyllysineCombined sources	1
Modified residueⁱ	412	PhosphoserineCombined sources	1
Modified residueⁱ	414	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q9Y6E2
PaxDbⁱ	Q9Y6E2
PeptideAtlas More...PeptideAtlasⁱ	Q9Y6E2
PRIDEⁱ	Q9Y6E2
ProteomicsDBⁱ	86659

PTM databases

iPTMnetⁱ	Q9Y6E2
PhosphoSitePlusⁱ	Q9Y6E2
SwissPalmⁱ	Q9Y6E2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000136261 Expressed in 238 organ(s), highest expression level in chorionic villus
CleanExⁱ	HS_BZW2
ExpressionAtlasⁱ	Q9Y6E2 baseline and differential
Genevisibleⁱ	Q9Y6E2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA022813 HPA026709

HPAⁱ

HPA022813
HPA026709

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
EIF2S2	P20042	2	EBI-1051021,EBI-711977

With

Entry

#Exp.

IntAct

Notes

EIF2S2

P20042

EBI-1051021,EBI-711977

GO - Molecular functionⁱ

cadherin binding
Source: BHF-UCL
Inferred from high throughput direct assayⁱ
- 25468996

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	118793, 72 interactors
IntActⁱ	Q9Y6E2, 10 interactors
Molecular INTeraction database More...MINTⁱ	Q9Y6E2
STRINGⁱ	9606.ENSP00000258761

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9Y6E2
SMRⁱ	Q9Y6E2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	248 – 415	W2PROSITE-ProRule annotationAdd BLAST		168

Sequence similaritiesⁱ

Belongs to the BZW family.Curated

Phylogenomic databases

eggNOGⁱ	KOG2297 Eukaryota ENOG410XR08 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012561
HOGENOMⁱ	HOG000252932
HOVERGENⁱ	HBG080940
InParanoidⁱ	Q9Y6E2
OMAⁱ	FMNKHQK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G090E
PhylomeDBⁱ	Q9Y6E2
TreeFamⁱ	TF324313

Family and domain databases

Gene3Dⁱ	1.25.40.180, 1 hit
InterProⁱ	View protein in InterPro IPR016024 ARM-type_fold IPR016021 MIF4-like_sf IPR003307 W2_domain
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02020 W2, 1 hit
SMARTⁱ	View protein in SMART SM00515 eIF5C, 1 hit
SUPFAMⁱ	SSF48371 SSF48371, 1 hit
PROSITEⁱ	View protein in PROSITE PS51363 W2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 9 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9Y6E2-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK 
        60         70         80         90        100
FLDSTGSRLD YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS 
       110        120        130        140        150
ANEDHETIRN YAQVFNKLIR RYKYLEKAFE DEMKKLLLFL KAFSETEQTK 
       160        170        180        190        200
LAMLSGILLG NGTLPATILT SLFTDSLVKE GIAASFAVKL FKAWMAEKDA 
       210        220        230        240        250
NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK ELSDFLRVQQ 
       260        270        280        290        300
SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC 
       310        320        330        340        350
IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL ILLQKVQEYC 
       360        370        380        390        400
YDNIHFMKAF QKIVVLFYKA DVLSEEAILK WYKEAHVAKG KSVFLDQMKK 
       410 
FVEWLQNAEE ESESEGEEN

Length:419

Mass (Da):48,162

Last modified:November 1, 1999 - v1

Checksum:ⁱ7ABFE7A51501E721

Isoform 2 (identifier: Q9Y6E2-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
182-201: IAASFAVKLFKAWMAEKDAN → NEAPVFSPVRQQKKNKVTDS
202-419: Missing.

« Hide

        10         20         30         40         50
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK 
        60         70         80         90        100
FLDSTGSRLD YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS 
       110        120        130        140        150
ANEDHETIRN YAQVFNKLIR RYKYLEKAFE DEMKKLLLFL KAFSETEQTK 
       160        170        180        190        200
LAMLSGILLG NGTLPATILT SLFTDSLVKE GNEAPVFSPV RQQKKNKVTD 

S

Note: No experimental confirmation available.

Show »

Length:201

Mass (Da):22,819

Checksum:ⁱ894B75B91E22764F

Computationally mapped potential isoform sequencesⁱ

There are 9 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

B5MCE7	B5MCE7_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2 (Basic leucine zipper and W2 domains 2, isoform CRA_b)	BZW2 hCG_19293	225	Annotation score:
B5MCH7	B5MCH7_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	343	Annotation score:
E7ETZ4	E7ETZ4_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	408	Annotation score:
E9PFD4	E9PFD4_HUMAN	BZW2 protein BZW2 protein (Basic leucine zipper and W2 domain-containing protein 2)	BZW2	189	Annotation score:
Q75MG1	Q75MG1_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	274	Annotation score:
C9JF98	C9JF98_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	162	Annotation score:
F8WDX8	F8WDX8_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	170	Annotation score:
E7EMS9	E7EMS9_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	208	Annotation score:
E9PFE3	E9PFE3_HUMAN	Basic leucine zipper and W2 domain-... Basic leucine zipper and W2 domain-containing protein 2	BZW2	161	Annotation score:

Sequence cautionⁱ

The sequence AAI07758 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	203	V → G in AAG39278 (Ref. 1) Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_033642	44	D → A. Corresponds to variant dbSNP:rs35233079Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_055568	182 – 201	IAASF…EKDAN → NEAPVFSPVRQQKKNKVTDS in isoform 2. 1 PublicationAdd BLAST		20
Alternative sequenceⁱVSP_055569	202 – 419	Missing in isoform 2. 1 PublicationAdd BLAST		218

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF110323 mRNA Translation: AAG39278.1 AF083246 mRNA Translation: AAD39844.1 AK001218 mRNA Translation: BAA91562.1 AK027837 mRNA Translation: BAB55401.1 CH236948 Genomic DNA Translation: EAL24285.1 CH471073 Genomic DNA Translation: EAW93675.1 CH471073 Genomic DNA Translation: EAW93678.1 BC003056 mRNA Translation: AAH03056.1 BC008453 mRNA Translation: AAH08453.1 BC009597 mRNA Translation: AAH09597.1 BC107757 mRNA Translation: AAI07758.1 Sequence problems.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5362.1 [Q9Y6E2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001153239.1, NM_001159767.1 [Q9Y6E2-1] NP_054757.1, NM_014038.2 [Q9Y6E2-1] XP_006715769.1, XM_006715706.1 XP_006715770.1, XM_006715707.1 [Q9Y6E2-1] XP_006715771.1, XM_006715708.1 [Q9Y6E2-1]
UniGeneⁱ	Hs.487635

Genome annotation databases

Ensemblⁱ	ENST00000258761; ENSP00000258761; ENSG00000136261 [Q9Y6E2-1] ENST00000433922; ENSP00000397249; ENSG00000136261 [Q9Y6E2-1]
GeneIDⁱ	28969
KEGGⁱ	hsa:28969
UCSC genome browser More...UCSCⁱ	uc003stj.3 human [Q9Y6E2-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Protein	Similar proteins		Species	Score	Length	Source
Q9Y6E2	Basic leucine zipper and W2 domain-containing protein 2		HUMAN		343	UniRef100_Q9Y6E2
Basic leucine zipper and W2 domain-containin protein 2-like protein (Fragment)		HORSE		365
BZW2 isoform 9 (Fragment)		PONAB		408
BZW2 isoform 1 (Fragment)		PANTR		408
Basic leucine zipper and W2 domains 2 (Fragment)		MUSPF		421
+35

Protein	Similar proteins		Species	Score	Length	Source
Q9Y6E2	Basic leucine zipper and W2 domain-containing protein 2		HUMAN		343	UniRef90_Q9Y6E2
Basic leucine zipper and W2 domain-containin protein 2-like protein (Fragment)		HORSE		365
BZW2 isoform 9 (Fragment)		PONAB		408
BZW2 isoform 1 (Fragment)		PANTR		408
Basic leucine zipper and W2 domains 2 (Fragment)		MUSPF		421
+121
Q9Y6E2-2	Similar to HSPC028 (Fragment)		BOVIN		163	UniRef90_Q9Y6E2-2

Protein	Similar proteins		Species	Score	Length	Source
Q9Y6E2	Basic leucine zipper and W2 domain-containing protein 2		HUMAN		343	UniRef50_Q9Y6E2
Basic leucine zipper and W2 domain-containin protein 2-like protein (Fragment)		HORSE		365
BZW2 isoform 9 (Fragment)		PONAB		408
BZW2 isoform 1 (Fragment)		PANTR		408
Basic leucine zipper and W2 domains 2 (Fragment)		MUSPF		421
+142
Q9Y6E2-2	Similar to HSPC028 (Fragment)		BOVIN		163	UniRef50_Q9Y6E2-2
Protein extra bases (Fragment)		LYGHE		196
Basic leucine zipper and W2 domain-containing protein 1 (Fragment)		Stegodyphus mimosarum		227
Putative basic leucine zipper		HOTJU		226
Uncharacterized protein (Fragment)		Cuerna arida		223
+2

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF110323 mRNA Translation: AAG39278.1 AF083246 mRNA Translation: AAD39844.1 AK001218 mRNA Translation: BAA91562.1 AK027837 mRNA Translation: BAB55401.1 CH236948 Genomic DNA Translation: EAL24285.1 CH471073 Genomic DNA Translation: EAW93675.1 CH471073 Genomic DNA Translation: EAW93678.1 BC003056 mRNA Translation: AAH03056.1 BC008453 mRNA Translation: AAH08453.1 BC009597 mRNA Translation: AAH09597.1 BC107757 mRNA Translation: AAI07758.1 Sequence problems.
CCDSⁱ	CCDS5362.1 [Q9Y6E2-1]
RefSeqⁱ	NP_001153239.1, NM_001159767.1 [Q9Y6E2-1] NP_054757.1, NM_014038.2 [Q9Y6E2-1] XP_006715769.1, XM_006715706.1 XP_006715770.1, XM_006715707.1 [Q9Y6E2-1] XP_006715771.1, XM_006715708.1 [Q9Y6E2-1]
UniGeneⁱ	Hs.487635

3D structure databases

ProteinModelPortalⁱ	Q9Y6E2
SMRⁱ	Q9Y6E2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	118793, 72 interactors
IntActⁱ	Q9Y6E2, 10 interactors
MINTⁱ	Q9Y6E2
STRINGⁱ	9606.ENSP00000258761

PTM databases

iPTMnetⁱ	Q9Y6E2
PhosphoSitePlusⁱ	Q9Y6E2
SwissPalmⁱ	Q9Y6E2

Polymorphism and mutation databases

BioMutaⁱ	BZW2
DMDMⁱ	74762077

Proteomic databases

EPDⁱ	Q9Y6E2
PaxDbⁱ	Q9Y6E2
PeptideAtlasⁱ	Q9Y6E2
PRIDEⁱ	Q9Y6E2
ProteomicsDBⁱ	86659

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	28969
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000258761; ENSP00000258761; ENSG00000136261 [Q9Y6E2-1] ENST00000433922; ENSP00000397249; ENSG00000136261 [Q9Y6E2-1]
GeneIDⁱ	28969
KEGGⁱ	hsa:28969
UCSCⁱ	uc003stj.3 human [Q9Y6E2-1]

Organism-specific databases

CTDⁱ	28969
DisGeNETⁱ	28969
EuPathDBⁱ	HostDB:ENSG00000136261.14
GeneCardsⁱ	BZW2
HGNCⁱ	HGNC:18808 BZW2
HPAⁱ	HPA022813 HPA026709
neXtProtⁱ	NX_Q9Y6E2
OpenTargetsⁱ	ENSG00000136261
PharmGKBⁱ	PA38690
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2297 Eukaryota ENOG410XR08 LUCA
GeneTreeⁱ	ENSGT00390000012561
HOGENOMⁱ	HOG000252932
HOVERGENⁱ	HBG080940
InParanoidⁱ	Q9Y6E2
OMAⁱ	FMNKHQK
OrthoDBⁱ	EOG091G090E
PhylomeDBⁱ	Q9Y6E2
TreeFamⁱ	TF324313

Miscellaneous databases

ChiTaRSⁱ	BZW2 human
GeneWikiⁱ	BZW2
GenomeRNAiⁱ	28969
Protein Ontology More...PROⁱ	PR:Q9Y6E2

Gene expression databases

Bgeeⁱ	ENSG00000136261 Expressed in 238 organ(s), highest expression level in chorionic villus
CleanExⁱ	HS_BZW2
ExpressionAtlasⁱ	Q9Y6E2 baseline and differential
Genevisibleⁱ	Q9Y6E2 HS

Family and domain databases

Gene3Dⁱ	1.25.40.180, 1 hit
InterProⁱ	View protein in InterPro IPR016024 ARM-type_fold IPR016021 MIF4-like_sf IPR003307 W2_domain
Pfamⁱ	View protein in Pfam PF02020 W2, 1 hit
SMARTⁱ	View protein in SMART SM00515 eIF5C, 1 hit
SUPFAMⁱ	SSF48371 SSF48371, 1 hit
PROSITEⁱ	View protein in PROSITE PS51363 W2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	BZW2_HUMAN
Accessionⁱ	Q9Y6E2Primary (citable) accession number: Q9Y6E2 Secondary accession number(s): A4D123 , Q3B779, Q96JW5, Q9H3F7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
	Last sequence update:	November 1, 1999
	Last modified:	October 10, 2018
	This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM

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UniProtKB - Q9Y6E2 (BZW2_HUMAN)

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Basic leucine zipper and W2 domain-containing protein 2

BZW2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ