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UniProtKB - Q9Y676 (RT18B_HUMAN)

Entry version 171 (02 Jun 2021)
Sequence version 1 (01 Nov 1999)
Previous versions | rss
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Protein

28S ribosomal protein S18b, mitochondrial

Gene

MRPS18B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

There are 3 mitochondrial isoforms of bS18 in mammalia, localizing to 3 distinct sites in the mitoribosome. bS18m (bs18c) binds to the same site as bacterial bS18, mS40 (bS18b, this protein) binds to a novel location of the 28S small subunit, and mL66 (bS18a) binds to the 39S large subunit.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9Y676

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-5368286, Mitochondrial translation initiation
R-HSA-5389840, Mitochondrial translation elongation
R-HSA-5419276, Mitochondrial translation termination

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q9Y676

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
28S ribosomal protein S18b, mitochondrial
Short name:
MRP-S18-b
Short name:
Mrps18-b
Short name:
S18mt-b
Alternative name(s):
28S ribosomal protein S18-2, mitochondrial
Short name:
MRP-S18-2
Mitochondrial small ribosomal subunit protein bS18b1 Publication
Mitochondrial small ribosomal subunit protein mS401 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRPS18B
Synonyms:C6orf14
ORF Names:HSPC183, PTD017
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:14516, MRPS18B

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		611982, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y676

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000204568.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		28973

Open Targets

More...OpenTargetsi		ENSG00000204568

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31004

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y676, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MRPS18B

Domain mapping of disease mutations (DMDM)

More...DMDMi		24212203

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 35MitochondrionBy similarityAdd BLAST35
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003062736 – 25828S ribosomal protein S18b, mitochondrialAdd BLAST223

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei38PhosphoserineCombined sources1
Modified residuei49PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y676

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y676

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y676

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Y676

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y676

PeptideAtlas

More...PeptideAtlasi		Q9Y676

PRoteomics IDEntifications database

More...PRIDEi		Q9Y676

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		86614

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y676

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y676

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9Y676

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000204568, Expressed in liver and 255 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y676, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y676, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000204568, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. mS40 has a zinc binding site.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		118797, 215 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5225, 28S mitochondrial small ribosomal subunit

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9Y676

Database of interacting proteins

More...DIPi		DIP-29894N

Protein interaction database and analysis system

More...IntActi		Q9Y676, 66 interactors

Molecular INTeraction database

More...MINTi		Q9Y676

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000259873

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y676, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y676

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni214 – 258DisorderedSequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi244 – 258Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4021, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010554

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_089746_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y676

Identification of Orthologs from Complete Genome Data

More...OMAi		PWEYLET

Database of Orthologous Groups

More...OrthoDBi		1023024at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y676

TreeFam database of animal gene trees

More...TreeFami		TF315059

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		4.10.640.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR040054, MRPS18B
IPR001648, Ribosomal_S18
IPR036870, Ribosomal_S18_sf

The PANTHER Classification System

More...PANTHERi		PTHR13329, PTHR13329, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01084, Ribosomal_S18, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46911, SSF46911, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y676-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASVLNTVL RRLPMLSLFR GSHRVQVPLQ TLCTKAPSEE DSLSSVPISP 
        60         70         80         90        100
YKDEPWKYLE SEEYQERYGS RPVWADYRRN HKGGVPPQRT RKTCIRRNKV 
       110        120        130        140        150
VGNPCPICRD HKLHVDFRNV KLLEQFVCAH TGIIFYAPYT GVCVKQHKRL 
       160        170        180        190        200
TQAIQKARDH GLLIYHIPQV EPRDLDFSTS HGAVSATPPA PTLVSGDPWY 
       210        220        230        240        250
PWYNWKQPPE RELSRLRRLY QGHLQEESGP PPESMPKMPP RTPAEASSTG 

QTGPQSAL
Length:258
Mass (Da):29,396
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB4C83E5593796C5D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JIC6A0A0G2JIC6_HUMAN
28S ribosomal protein S18b, mitocho...
MRPS18B
215Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti196G → S in AAH05373 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052056230P → A. Corresponds to variant dbSNP:rs34315095Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF100761 mRNA Translation: AAD43025.1
AF151017 mRNA Translation: AAF36103.1
AL050361 mRNA Translation: CAH56415.1
AB110933 Genomic DNA Translation: BAD13699.1
AB110934 Genomic DNA Translation: BAD13700.1
AB202094 Genomic DNA Translation: BAE78614.1
AL662800 Genomic DNA No translation available.
AL662825 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
BX119957 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX248507 Genomic DNA No translation available.
CR753328 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03304.1
BC005373 mRNA Translation: AAH05373.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4682.1

NCBI Reference Sequences

More...RefSeqi		NP_054765.1, NM_014046.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000259873; ENSP00000259873; ENSG00000204568
ENST00000327800; ENSP00000383438; ENSG00000203624
ENST00000412451; ENSP00000402718; ENSG00000223775
ENST00000426945; ENSP00000397790; ENSG00000229861
ENST00000430402; ENSP00000398494; ENSG00000233813
ENST00000451032; ENSP00000415703; ENSG00000226111
ENST00000454427; ENSP00000414972; ENSG00000227420

Database of genes from NCBI RefSeq genomes

More...GeneIDi		28973

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:28973

UCSC genome browser

More...UCSCi		uc003nqo.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF100761 mRNA Translation: AAD43025.1
AF151017 mRNA Translation: AAF36103.1
AL050361 mRNA Translation: CAH56415.1
AB110933 Genomic DNA Translation: BAD13699.1
AB110934 Genomic DNA Translation: BAD13700.1
AB202094 Genomic DNA Translation: BAE78614.1
AL662800 Genomic DNA No translation available.
AL662825 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
BX119957 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX248507 Genomic DNA No translation available.
CR753328 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03304.1
BC005373 mRNA Translation: AAH05373.1
CCDSiCCDS4682.1
RefSeqiNP_054765.1, NM_014046.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J9Melectron microscopy3.50AO1-258[»]
6NU2electron microscopy3.90AO52-236[»]
6NU3electron microscopy4.40AO52-236[»]
6RW4electron microscopy2.97O1-258[»]
6RW5electron microscopy3.14O1-258[»]
6VLZelectron microscopy2.97AO1-258[»]
6VMIelectron microscopy2.96AO1-258[»]
6ZM5electron microscopy2.89AO1-258[»]
6ZM6electron microscopy2.59AO1-258[»]
6ZS9electron microscopy4.00AO1-258[»]
6ZSAelectron microscopy4.00AO1-258[»]
6ZSBelectron microscopy4.50AO1-258[»]
6ZSCelectron microscopy3.50AO1-258[»]
6ZSDelectron microscopy3.70AO1-258[»]
6ZSEelectron microscopy5.00AO1-236[»]
6ZSGelectron microscopy4.00AO1-258[»]
7A5Felectron microscopy4.40O61-258[»]
7A5Gelectron microscopy4.33O61-258[»]
7A5Ielectron microscopy3.70O61-258[»]
7A5Kelectron microscopy3.70O61-258[»]
SMRiQ9Y676
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi118797, 215 interactors
ComplexPortaliCPX-5225, 28S mitochondrial small ribosomal subunit
CORUMiQ9Y676
DIPiDIP-29894N
IntActiQ9Y676, 66 interactors
MINTiQ9Y676
STRINGi9606.ENSP00000259873

PTM databases

iPTMnetiQ9Y676
PhosphoSitePlusiQ9Y676
SwissPalmiQ9Y676

Genetic variation databases

BioMutaiMRPS18B
DMDMi24212203

Proteomic databases

EPDiQ9Y676
jPOSTiQ9Y676
MassIVEiQ9Y676
MaxQBiQ9Y676
PaxDbiQ9Y676
PeptideAtlasiQ9Y676
PRIDEiQ9Y676
ProteomicsDBi86614

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26399, 82 antibodies

The DNASU plasmid repository

More...DNASUi		28973

Genome annotation databases

EnsembliENST00000259873; ENSP00000259873; ENSG00000204568
ENST00000327800; ENSP00000383438; ENSG00000203624
ENST00000412451; ENSP00000402718; ENSG00000223775
ENST00000426945; ENSP00000397790; ENSG00000229861
ENST00000430402; ENSP00000398494; ENSG00000233813
ENST00000451032; ENSP00000415703; ENSG00000226111
ENST00000454427; ENSP00000414972; ENSG00000227420
GeneIDi28973
KEGGihsa:28973
UCSCiuc003nqo.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		28973
DisGeNETi28973

GeneCards: human genes, protein and diseases

More...GeneCardsi		MRPS18B
HGNCiHGNC:14516, MRPS18B
HPAiENSG00000204568, Low tissue specificity
MIMi611982, gene
neXtProtiNX_Q9Y676
OpenTargetsiENSG00000204568
PharmGKBiPA31004
VEuPathDBiHostDB:ENSG00000204568.11

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4021, Eukaryota
GeneTreeiENSGT00390000010554
HOGENOMiCLU_089746_0_0_1
InParanoidiQ9Y676
OMAiPWEYLET
OrthoDBi1023024at2759
PhylomeDBiQ9Y676
TreeFamiTF315059

Enzyme and pathway databases

PathwayCommonsiQ9Y676
ReactomeiR-HSA-5368286, Mitochondrial translation initiation
R-HSA-5389840, Mitochondrial translation elongation
R-HSA-5419276, Mitochondrial translation termination
SIGNORiQ9Y676

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		28973, 304 hits in 1003 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MRPS18B, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		MRPS18B

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		28973
PharosiQ9Y676, Tdark

Protein Ontology

More...PROi		PR:Q9Y676
RNActiQ9Y676, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000204568, Expressed in liver and 255 other tissues
ExpressionAtlasiQ9Y676, baseline and differential
GenevisibleiQ9Y676, HS

Family and domain databases

Gene3Di4.10.640.10, 1 hit
InterProiView protein in InterPro
IPR040054, MRPS18B
IPR001648, Ribosomal_S18
IPR036870, Ribosomal_S18_sf
PANTHERiPTHR13329, PTHR13329, 1 hit
PfamiView protein in Pfam
PF01084, Ribosomal_S18, 1 hit
SUPFAMiSSF46911, SSF46911, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRT18B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y676
Secondary accession number(s): A6NDQ0, Q659G4, Q9BS27
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: November 1, 1999
Last modified: June 2, 2021
This is version 171 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  7. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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