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Entry version 152 (18 Sep 2019)
Sequence version 2 (11 Jul 2001)
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Protein

Sorting nexin-11

Gene

SNX11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei59Phosphatidylinositol 3-phosphate1
Binding sitei85Phosphatidylinositol 3-phosphateBy similarity1
Binding sitei99Phosphatidylinositol 3-phosphateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • phosphatidylinositol phosphate binding Source: UniProtKB

GO - Biological processi

  • intracellular protein transport Source: InterPro
  • vesicle organization Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport
LigandLipid-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sorting nexin-11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNX11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14975 SNX11

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614906 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y5W9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi59R → A: Abolishes lipid-binding. 1 Publication1
Mutagenesisi135 – 139IEACV → AAAAA: Impairs function in membrane trafficking. 1 Publication5

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000002919

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37951

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SNX11

Domain mapping of disease mutations (DMDM)

More...
DMDMi
14916716

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002138561 – 270Sorting nexin-11Add BLAST270

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y5W9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y5W9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y5W9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y5W9

PeptideAtlas

More...
PeptideAtlasi
Q9Y5W9

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y5W9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86524 [Q9Y5W9-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y5W9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y5W9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9Y5W9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000002919 Expressed in 216 organ(s), highest expression level in epithelium of mammary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y5W9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y5W9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044787
HPA054660

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118960, 23 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y5W9, 26 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000377059

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1270
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y5W9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 132PXPROSITE-ProRule annotationAdd BLAST117

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni135 – 139Important for membrane trafficking5

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sorting nexin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2527 Eukaryota
COG5391 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160113

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231108

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y5W9

KEGG Orthology (KO)

More...
KOi
K17924

Identification of Orthologs from Complete Genome Data

More...
OMAi
GWVQEER

Database of Orthologous Groups

More...
OrthoDBi
1407986at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y5W9

TreeFam database of animal gene trees

More...
TreeFami
TF332117

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1520.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028655 SNX11

The PANTHER Classification System

More...
PANTHERi
PTHR46209:SF1 PTHR46209:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00787 PX, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00312 PX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF64268 SSF64268, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50195 PX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y5W9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGFWCRMSEN QEQEEVITVR VQDPRVQNEG SWNSYVDYKI FLHTNSKAFT
60 70 80 90 100
AKTSCVRRRY REFVWLRKQL QRNAGLVPVP ELPGKSTFFG TSDEFIEKRR
110 120 130 140 150
QGLQHFLEKV LQSVVLLSDS QLHLFLQSQL SVPEIEACVQ GRSTMTVSDA
160 170 180 190 200
ILRYAMSNCG WAQEERQSSS HLAKGDQPKS CCFLPRSGRR SSPSPPPSEE
210 220 230 240 250
KDHLEVWAPV VDSEVPSLES PTLPPLSSPL CCDFGRPKEG TSTLQSVRRA
260 270
VGGDHAVPLD PGQLETVLEK
Length:270
Mass (Da):30,433
Last modified:July 11, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE6839B7415F1724F
GO
Isoform 2 (identifier: Q9Y5W9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-14: MGFWCRMSENQEQE → MVCREQ

Note: No experimental confirmation available.
Show »
Length:262
Mass (Da):29,423
Checksum:i4DC0C01993F8151D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QLV8J3QLV8_HUMAN
Sorting nexin-11
SNX11
254Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KTN6J3KTN6_HUMAN
Sorting nexin-11
SNX11
177Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRB9J3QRB9_HUMAN
Sorting nexin-11
SNX11
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKV3J3QKV3_HUMAN
Sorting nexin-11
SNX11
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRW4J3QRW4_HUMAN
Sorting nexin-11
SNX11
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B4DJI7B4DJI7_HUMAN
Sorting nexin-11
SNX11
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD27834 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0565941 – 14MGFWC…NQEQE → MVCREQ in isoform 2. 1 PublicationAdd BLAST14

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF121861 mRNA Translation: AAD27834.1 Different initiation.
BT006723 mRNA Translation: AAP35369.1
AK023932 mRNA Translation: BAB14732.1
AK091852 mRNA Translation: BAG52428.1
AK298551 mRNA Translation: BAG60747.1
AK316374 mRNA Translation: BAH14745.1
AC006468 Genomic DNA No translation available.
CH471109 Genomic DNA Translation: EAW94754.1
BC000768 mRNA Translation: AAH00768.1
BC103721 mRNA Translation: AAI03722.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11526.1 [Q9Y5W9-1]
CCDS82152.1 [Q9Y5W9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001317249.1, NM_001330320.1 [Q9Y5W9-2]
NP_037455.2, NM_013323.2 [Q9Y5W9-1]
NP_689450.1, NM_152244.1 [Q9Y5W9-1]
XP_005257317.1, XM_005257260.3 [Q9Y5W9-1]
XP_005257319.1, XM_005257262.3 [Q9Y5W9-2]
XP_011522999.1, XM_011524697.2 [Q9Y5W9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359238; ENSP00000352175; ENSG00000002919 [Q9Y5W9-1]
ENST00000393405; ENSP00000377059; ENSG00000002919 [Q9Y5W9-1]
ENST00000580219; ENSP00000462188; ENSG00000002919 [Q9Y5W9-2]
ENST00000582104; ENSP00000463948; ENSG00000002919 [Q9Y5W9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29916

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:29916

UCSC genome browser

More...
UCSCi
uc002inf.2 human [Q9Y5W9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF121861 mRNA Translation: AAD27834.1 Different initiation.
BT006723 mRNA Translation: AAP35369.1
AK023932 mRNA Translation: BAB14732.1
AK091852 mRNA Translation: BAG52428.1
AK298551 mRNA Translation: BAG60747.1
AK316374 mRNA Translation: BAH14745.1
AC006468 Genomic DNA No translation available.
CH471109 Genomic DNA Translation: EAW94754.1
BC000768 mRNA Translation: AAH00768.1
BC103721 mRNA Translation: AAI03722.1
CCDSiCCDS11526.1 [Q9Y5W9-1]
CCDS82152.1 [Q9Y5W9-2]
RefSeqiNP_001317249.1, NM_001330320.1 [Q9Y5W9-2]
NP_037455.2, NM_013323.2 [Q9Y5W9-1]
NP_689450.1, NM_152244.1 [Q9Y5W9-1]
XP_005257317.1, XM_005257260.3 [Q9Y5W9-1]
XP_005257319.1, XM_005257262.3 [Q9Y5W9-2]
XP_011522999.1, XM_011524697.2 [Q9Y5W9-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4IKBX-ray1.78A/B7-142[»]
4IKDX-ray1.60A7-170[»]
SMRiQ9Y5W9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi118960, 23 interactors
IntActiQ9Y5W9, 26 interactors
STRINGi9606.ENSP00000377059

PTM databases

iPTMnetiQ9Y5W9
PhosphoSitePlusiQ9Y5W9
SwissPalmiQ9Y5W9

Polymorphism and mutation databases

BioMutaiSNX11
DMDMi14916716

Proteomic databases

EPDiQ9Y5W9
jPOSTiQ9Y5W9
MassIVEiQ9Y5W9
PaxDbiQ9Y5W9
PeptideAtlasiQ9Y5W9
PRIDEiQ9Y5W9
ProteomicsDBi86524 [Q9Y5W9-1]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
29916
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359238; ENSP00000352175; ENSG00000002919 [Q9Y5W9-1]
ENST00000393405; ENSP00000377059; ENSG00000002919 [Q9Y5W9-1]
ENST00000580219; ENSP00000462188; ENSG00000002919 [Q9Y5W9-2]
ENST00000582104; ENSP00000463948; ENSG00000002919 [Q9Y5W9-2]
GeneIDi29916
KEGGihsa:29916
UCSCiuc002inf.2 human [Q9Y5W9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
29916

GeneCards: human genes, protein and diseases

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GeneCardsi
SNX11
HGNCiHGNC:14975 SNX11
HPAiHPA044787
HPA054660
MIMi614906 gene
neXtProtiNX_Q9Y5W9
OpenTargetsiENSG00000002919
PharmGKBiPA37951

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2527 Eukaryota
COG5391 LUCA
GeneTreeiENSGT00940000160113
HOGENOMiHOG000231108
InParanoidiQ9Y5W9
KOiK17924
OMAiGWVQEER
OrthoDBi1407986at2759
PhylomeDBiQ9Y5W9
TreeFamiTF332117

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SNX11 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
29916

Pharos

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Pharosi
Q9Y5W9

Protein Ontology

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PROi
PR:Q9Y5W9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000002919 Expressed in 216 organ(s), highest expression level in epithelium of mammary gland
ExpressionAtlasiQ9Y5W9 baseline and differential
GenevisibleiQ9Y5W9 HS

Family and domain databases

Gene3Di3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028655 SNX11
PANTHERiPTHR46209:SF1 PTHR46209:SF1, 1 hit
PfamiView protein in Pfam
PF00787 PX, 1 hit
SMARTiView protein in SMART
SM00312 PX, 1 hit
SUPFAMiSSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSNX11_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y5W9
Secondary accession number(s): B3KRL6
, B4DPY5, D3DTV0, Q53YC0, Q9H885
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 11, 2001
Last modified: September 18, 2019
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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