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Entry version 166 (08 May 2019)
Sequence version 4 (25 Oct 2002)
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Protein

Sorting nexin-13

Gene

SNX13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas.By similarity1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei612Phosphatidylinositol 3-phosphateBy similarity1
Binding sitei614Phosphatidylinositol 3-phosphate; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei639Phosphatidylinositol 3-phosphateBy similarity1
Binding sitei653Phosphatidylinositol 3-phosphateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionSignal transduction inhibitor
Biological processProtein transport, Transport
LigandLipid-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sorting nexin-13
Alternative name(s):
RGS domain- and PHOX domain-containing protein
RGS-PX1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNX13
Synonyms:KIAA0713
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21335 SNX13

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606589 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y5W8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23161

Open Targets

More...
OpenTargetsi
ENSG00000071189

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA129697240

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SNX13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
24418867

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002138601 – 968Sorting nexin-13Add BLAST968

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y5W8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y5W8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y5W8

PeptideAtlas

More...
PeptideAtlasi
Q9Y5W8

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y5W8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86522
86523 [Q9Y5W8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y5W8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y5W8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000071189 Expressed in 228 organ(s), highest expression level in stomach

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y5W8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y5W8 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116773, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y5W8, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000398789

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y5W8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini97 – 284PXAPROSITE-ProRule annotationAdd BLAST188
Domaini373 – 496RGSPROSITE-ProRule annotationAdd BLAST124
Domaini570 – 691PXPROSITE-ProRule annotationAdd BLAST122

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sorting nexin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IMHZ Eukaryota
ENOG410XRJ0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182856

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059640

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y5W8

KEGG Orthology (KO)

More...
KOi
K17925

Identification of Orthologs from Complete Genome Data

More...
OMAi
FAFYILC

Database of Orthologous Groups

More...
OrthoDBi
187001at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y5W8

TreeFam database of animal gene trees

More...
TreeFami
TF324055

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06873 PX_SNX13, 1 hit
cd08719 RGS_SNX13, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1520.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001683 Phox
IPR003114 Phox_assoc
IPR036871 PX_dom_sf
IPR016137 RGS
IPR036305 RGS_sf
IPR037437 SNX13_PX
IPR037896 SNX13_RGS
IPR013937 Sorting_nexin_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08628 Nexin_C, 1 hit
PF00787 PX, 1 hit
PF02194 PXA, 1 hit
PF00615 RGS, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00312 PX, 1 hit
SM00313 PXA, 1 hit
SM00315 RGS, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48097 SSF48097, 1 hit
SSF64268 SSF64268, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50195 PX, 1 hit
PS51207 PXA, 1 hit
PS50132 RGS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y5W8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLTEASLSIW GWGSLGIVLF LITFGPFVIF YLTFYILCFV GGGLVVTLLF
60 70 80 90 100
GKTNSEKYLE QCEHSFLPPT SPGVPKCLEE MKREARTIKI DRRLTGANII
110 120 130 140 150
DEPLQQVIQF SLRDYVQYWY YTLSDDESFL LEIRQTLQNA LIQFATRSKE
160 170 180 190 200
IDWQPYFTTR IVDDFGTHLR VFRKAQQKIT EKDDQVKGTA EDLVDTFFEV
210 220 230 240 250
EVEMEKEVCR DLVCTSPKDE EGFLRDLCEV LLYLLLPPGD FQNKIMRYFV
260 270 280 290 300
REILARGILL PLINQLSDPD YINQYVIWMI RDSNCNYEAF MNIIKLSDNI
310 320 330 340 350
GELEAVRDKA AEELQYLRSL DTAGDDINTI KNQINSLLFV KKVCDSRIQR
360 370 380 390 400
LQSGKEINTV KLAANFGKLC TVPLDSILVD NVALQFFMDY MQQTGGQAHL
410 420 430 440 450
FFWMTVEGYR VTAQQQLEVL LSRQRDGKHQ TNQTKGLLRA AAVGIYEQYL
460 470 480 490 500
SEKASPRVTV DDYLVAKLAD TLNHEDPTPE IFDDIQRKVY ELMLRDERFY
510 520 530 540 550
PSFRQNALYV RMLAELDMLK DPSFRGSDDG DGESFNGSPT GSINLSLDDL
560 570 580 590 600
SNVSSDDSVQ LHAYISDTVY ADYDPYAVAG VCNDHGKTYA LYAITVHRRN
610 620 630 640 650
LNSEEMWKTY RRYSDFHDFH MRITEQFESL SSILKLPGKK TFNNMDRDFL
660 670 680 690 700
EKRKKDLNAY LQLLLAPEMM KASPALAHYV YDFLENKAYS KGKGDFARKM
710 720 730 740 750
DTFVNPLRNS MRNVSNAVKS LPDSLAEGMT KMSDNMGKMS ERLGQDIKQS
760 770 780 790 800
FFKVPPLIPK TDSDPEHRRV SAQLDDNVDD NIPLRVMLLL MDEVFDLKER
810 820 830 840 850
NQWLRRNIKN LLQQLIRATY GDTINRKIVD HVDWMTSPEQ VADSVKRFRD
860 870 880 890 900
AFWPNGILAE AVPCRDKSIR MRTRVAGKTK LLAIMPDELK HIIGAETTRK
910 920 930 940 950
GILRVFEMFQ HNQLNRRMVY VFLEGFLETL FPQYKFRELF NKLHSRSKQM
960
QKYKQKLQTT QAPSLQKR
Length:968
Mass (Da):112,189
Last modified:October 25, 2002 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i532994AE0B347FB5
GO
Isoform 2 (identifier: Q9Y5W8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     569-579: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.
Show »
Length:957
Mass (Da):110,960
Checksum:iAC41207BE22F3557
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WUZ7A0A087WUZ7_HUMAN
Sorting nexin 13, isoform CRA_g
SNX13 hCG_2009798
888Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9NSH0Q9NSH0_HUMAN
Sorting nexin 13, isoform CRA_d
SNX13 DKFZp761E0611, hCG_2009798
189Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W8A9F8W8A9_HUMAN
Sorting nexin-13
SNX13
154Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WB11F8WB11_HUMAN
Sorting nexin-13
SNX13
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH22060 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA34433 differs from that shown. Reason: Frameshift at position 887.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti638G → E in BAA34433 (PubMed:11729322).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057333472L → S. Corresponds to variant dbSNP:rs35113148Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_006192569 – 579Missing in isoform 2. 2 PublicationsAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF420470 mRNA Translation: AAL37728.1
AB018256 mRNA Translation: BAA34433.1 Frameshift.
AK315135 mRNA Translation: BAG37586.1
AF121862 mRNA Translation: AAD27835.1
CH471073 Genomic DNA Translation: EAW93690.1
BC022060 mRNA Translation: AAH22060.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47551.1 [Q9Y5W8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_055947.1, NM_015132.4 [Q9Y5W8-2]
XP_005249729.1, XM_005249672.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000428135; ENSP00000398789; ENSG00000071189 [Q9Y5W8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23161

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23161

UCSC genome browser

More...
UCSCi
uc003stv.4 human [Q9Y5W8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF420470 mRNA Translation: AAL37728.1
AB018256 mRNA Translation: BAA34433.1 Frameshift.
AK315135 mRNA Translation: BAG37586.1
AF121862 mRNA Translation: AAD27835.1
CH471073 Genomic DNA Translation: EAW93690.1
BC022060 mRNA Translation: AAH22060.1 Different initiation.
CCDSiCCDS47551.1 [Q9Y5W8-2]
RefSeqiNP_055947.1, NM_015132.4 [Q9Y5W8-2]
XP_005249729.1, XM_005249672.1

3D structure databases

SMRiQ9Y5W8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116773, 10 interactors
IntActiQ9Y5W8, 4 interactors
STRINGi9606.ENSP00000398789

PTM databases

iPTMnetiQ9Y5W8
PhosphoSitePlusiQ9Y5W8

Polymorphism and mutation databases

BioMutaiSNX13
DMDMi24418867

Proteomic databases

EPDiQ9Y5W8
jPOSTiQ9Y5W8
PaxDbiQ9Y5W8
PeptideAtlasiQ9Y5W8
PRIDEiQ9Y5W8
ProteomicsDBi86522
86523 [Q9Y5W8-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
23161
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000428135; ENSP00000398789; ENSG00000071189 [Q9Y5W8-2]
GeneIDi23161
KEGGihsa:23161
UCSCiuc003stv.4 human [Q9Y5W8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23161
DisGeNETi23161

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SNX13

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0006501
HGNCiHGNC:21335 SNX13
MIMi606589 gene
neXtProtiNX_Q9Y5W8
OpenTargetsiENSG00000071189
PharmGKBiPA129697240

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IMHZ Eukaryota
ENOG410XRJ0 LUCA
GeneTreeiENSGT00950000182856
HOGENOMiHOG000059640
InParanoidiQ9Y5W8
KOiK17925
OMAiFAFYILC
OrthoDBi187001at2759
PhylomeDBiQ9Y5W8
TreeFamiTF324055

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SNX13

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
23161

Protein Ontology

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PROi
PR:Q9Y5W8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000071189 Expressed in 228 organ(s), highest expression level in stomach
ExpressionAtlasiQ9Y5W8 baseline and differential
GenevisibleiQ9Y5W8 HS

Family and domain databases

CDDicd06873 PX_SNX13, 1 hit
cd08719 RGS_SNX13, 1 hit
Gene3Di3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR001683 Phox
IPR003114 Phox_assoc
IPR036871 PX_dom_sf
IPR016137 RGS
IPR036305 RGS_sf
IPR037437 SNX13_PX
IPR037896 SNX13_RGS
IPR013937 Sorting_nexin_C
PfamiView protein in Pfam
PF08628 Nexin_C, 1 hit
PF00787 PX, 1 hit
PF02194 PXA, 1 hit
PF00615 RGS, 1 hit
SMARTiView protein in SMART
SM00312 PX, 1 hit
SM00313 PXA, 1 hit
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit
PS51207 PXA, 1 hit
PS50132 RGS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSNX13_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y5W8
Secondary accession number(s): B2RCI9
, O94821, Q8WVZ2, Q8WXH8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: October 25, 2002
Last modified: May 8, 2019
This is version 166 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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