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Entry version 166 (13 Feb 2019)
Sequence version 1 (01 Nov 1999)
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Protein

Nucleoside diphosphate kinase 7

Gene

NME7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei99ATPBy similarity1
Binding sitei145ATPBy similarity1
Binding sitei193ATPBy similarity1
Binding sitei203ATPBy similarity1
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei206Pros-phosphohistidine intermediateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processNucleotide metabolism
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleoside diphosphate kinase 7 (EC:2.7.4.6)
Short name:
NDK 7
Short name:
NDP kinase 7
Alternative name(s):
nm23-H7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NME7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000143156.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20461 NME7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613465 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y5B8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
29922

MalaCards human disease database

More...
MalaCardsi
NME7

Open Targets

More...
OpenTargetsi
ENSG00000143156

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
101063 Situs inversus totalis

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134962167

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NME7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
12230353

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001371301 – 376Nucleoside diphosphate kinase 7Add BLAST376

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y5B8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y5B8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y5B8

PeptideAtlas

More...
PeptideAtlasi
Q9Y5B8

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y5B8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86336
86337 [Q9Y5B8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y5B8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y5B8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000143156 Expressed in 230 organ(s), highest expression level in cerebellar vermis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y5B8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y5B8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038014
HPA054289

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118963, 76 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y5B8, 107 interactors

Molecular INTeraction database

More...
MINTi
Q9Y5B8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356785

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Y5B8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y5B8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 91DM10PROSITE-ProRule annotationAdd BLAST89

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NDK family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0888 Eukaryota
COG0105 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158946

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000224566

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG006457

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y5B8

KEGG Orthology (KO)

More...
KOi
K00940

Identification of Orthologs from Complete Genome Data

More...
OMAi
NLELQYM

Database of Orthologous Groups

More...
OrthoDBi
1230088at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y5B8

TreeFam database of animal gene trees

More...
TreeFami
TF106374

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04415 NDPk7A, 1 hit
cd04412 NDPk7B, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.141, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR011410 NDPK7
IPR035525 NDPk7A
IPR037993 NDPk7B
IPR001564 Nucleoside_diP_kinase
IPR006602 Uncharacterised_DM10

The PANTHER Classification System

More...
PANTHERi
PTHR43109 PTHR43109, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00334 NDK, 2 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036503 NDK7, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01243 NUCDPKINASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00676 DM10, 1 hit
SM00562 NDK, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54919 SSF54919, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51336 DM10, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y5B8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNHSERFVFI AEWYDPNASL LRRYELLFYP GDGSVEMHDV KNHRTFLKRT
60 70 80 90 100
KYDNLHLEDL FIGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP
110 120 130 140 150
DAISKAGEII EIINKAGFTI TKLKMMMLSR KEALDFHVDH QSRPFFNELI
160 170 180 190 200
QFITTGPIIA MEILRDDAIC EWKRLLGPAN SGVARTDASE SIRALFGTDG
210 220 230 240 250
IRNAAHGPDS FASAAREMEL FFPSSGGCGP ANTAKFTNCT CCIVKPHAVS
260 270 280 290 300
EGLLGKILMA IRDAGFEISA MQMFNMDRVN VEEFYEVYKG VVTEYHDMVT
310 320 330 340 350
EMYSGPCVAM EIQQNNATKT FREFCGPADP EIARHLRPGT LRAIFGKTKI
360 370
QNAVHCTDLP EDGLLEVQYF FKILDN
Length:376
Mass (Da):42,492
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i67C121D6C36E7012
GO
Isoform 2 (identifier: Q9Y5B8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: Missing.

Show »
Length:340
Mass (Da):38,187
Checksum:i2FA9FE0342B05737
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DXC8B4DXC8_HUMAN
Nucleoside diphosphate kinase 7
NME7
339Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PNU1E9PNU1_HUMAN
Nucleoside diphosphate kinase 7
NME7
256Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0409961 – 36Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF153191 mRNA Translation: AAD34622.1
AK094513 mRNA Translation: BAG52881.1
AK290701 mRNA Translation: BAF83390.1
AL031726 Genomic DNA No translation available.
Z99758 Genomic DNA No translation available.
AL356852 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW90834.1
CH471067 Genomic DNA Translation: EAW90835.1
BC006983 mRNA Translation: AAH06983.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1277.1 [Q9Y5B8-1]
CCDS44274.1 [Q9Y5B8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_037462.1, NM_013330.4 [Q9Y5B8-1]
NP_932076.1, NM_197972.2 [Q9Y5B8-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.706952

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367811; ENSP00000356785; ENSG00000143156 [Q9Y5B8-1]
ENST00000472647; ENSP00000433341; ENSG00000143156 [Q9Y5B8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29922

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:29922

UCSC genome browser

More...
UCSCi
uc001gft.5 human [Q9Y5B8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF153191 mRNA Translation: AAD34622.1
AK094513 mRNA Translation: BAG52881.1
AK290701 mRNA Translation: BAF83390.1
AL031726 Genomic DNA No translation available.
Z99758 Genomic DNA No translation available.
AL356852 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW90834.1
CH471067 Genomic DNA Translation: EAW90835.1
BC006983 mRNA Translation: AAH06983.1
CCDSiCCDS1277.1 [Q9Y5B8-1]
CCDS44274.1 [Q9Y5B8-2]
RefSeqiNP_037462.1, NM_013330.4 [Q9Y5B8-1]
NP_932076.1, NM_197972.2 [Q9Y5B8-2]
UniGeneiHs.706952

3D structure databases

ProteinModelPortaliQ9Y5B8
SMRiQ9Y5B8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118963, 76 interactors
IntActiQ9Y5B8, 107 interactors
MINTiQ9Y5B8
STRINGi9606.ENSP00000356785

PTM databases

iPTMnetiQ9Y5B8
PhosphoSitePlusiQ9Y5B8

Polymorphism and mutation databases

BioMutaiNME7
DMDMi12230353

Proteomic databases

EPDiQ9Y5B8
jPOSTiQ9Y5B8
PaxDbiQ9Y5B8
PeptideAtlasiQ9Y5B8
PRIDEiQ9Y5B8
ProteomicsDBi86336
86337 [Q9Y5B8-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
29922
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367811; ENSP00000356785; ENSG00000143156 [Q9Y5B8-1]
ENST00000472647; ENSP00000433341; ENSG00000143156 [Q9Y5B8-2]
GeneIDi29922
KEGGihsa:29922
UCSCiuc001gft.5 human [Q9Y5B8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
29922
DisGeNETi29922
EuPathDBiHostDB:ENSG00000143156.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NME7
HGNCiHGNC:20461 NME7
HPAiHPA038014
HPA054289
MalaCardsiNME7
MIMi613465 gene
neXtProtiNX_Q9Y5B8
OpenTargetsiENSG00000143156
Orphaneti101063 Situs inversus totalis
PharmGKBiPA134962167

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0888 Eukaryota
COG0105 LUCA
GeneTreeiENSGT00940000158946
HOGENOMiHOG000224566
HOVERGENiHBG006457
InParanoidiQ9Y5B8
KOiK00940
OMAiNLELQYM
OrthoDBi1230088at2759
PhylomeDBiQ9Y5B8
TreeFamiTF106374

Enzyme and pathway databases

ReactomeiR-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NME7 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
29922

Protein Ontology

More...
PROi
PR:Q9Y5B8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000143156 Expressed in 230 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiQ9Y5B8 baseline and differential
GenevisibleiQ9Y5B8 HS

Family and domain databases

CDDicd04415 NDPk7A, 1 hit
cd04412 NDPk7B, 1 hit
Gene3Di3.30.70.141, 2 hits
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR011410 NDPK7
IPR035525 NDPk7A
IPR037993 NDPk7B
IPR001564 Nucleoside_diP_kinase
IPR006602 Uncharacterised_DM10
PANTHERiPTHR43109 PTHR43109, 1 hit
PfamiView protein in Pfam
PF00334 NDK, 2 hits
PIRSFiPIRSF036503 NDK7, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00676 DM10, 1 hit
SM00562 NDK, 2 hits
SUPFAMiSSF54919 SSF54919, 2 hits
PROSITEiView protein in PROSITE
PS51336 DM10, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNDK7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y5B8
Secondary accession number(s): A8K3T6
, A8MY09, B3KSW9, Q5TGZ4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1999
Last modified: February 13, 2019
This is version 166 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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