UniProtKB - Q9Y4C8 (RBM19_HUMAN)

BLAST

>sp|Q9Y4C8|RBM19_HUMAN Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3
MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL

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History
Entry version 168 (07 Nov 2018)
Sequence version 3 (05 Oct 2010)
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Protein

Probable RNA-binding protein 19

Gene

RBM19

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Plays a role in embryo pre-implantation development.By similarity

GO - Molecular functionⁱ

RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
- 22681889

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mRNA cis splicing, via spliceosome
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
multicellular organism development Source: UniProtKB-KW
positive regulation of embryonic development Source: UniProtKB
regulation of alternative mRNA splicing, via spliceosome
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental protein, RNA-binding

Molecular function

Developmental protein, RNA-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Probable RNA-binding protein 19 Alternative name(s): RNA-binding motif protein 19
Gene namesⁱ	Name:RBM19 Synonyms:KIAA0682
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 12

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000122965.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:29098 RBM19
MIMⁱ	616444 gene
neXtProtⁱ	NX_Q9Y4C8

Keywords - Cellular componentⁱ

Chromosome, Cytoplasm, Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	9904
Open Targets More...OpenTargetsⁱ	ENSG00000122965
PharmGKBⁱ	PA134886784

Polymorphism and mutation databases

BioMutaⁱ	RBM19
DMDMⁱ	308153566

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000081781	1 – 960	Probable RNA-binding protein 19Add BLAST		960

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	174	PhosphoserineCombined sources	1
Modified residueⁱ	176	PhosphoserineCombined sources	1
Modified residueⁱ	180	PhosphoserineCombined sources	1
Cross-linkⁱ	481	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	936	PhosphoserineCombined sources	1
Modified residueⁱ	949	PhosphoserineCombined sources	1
Modified residueⁱ	951	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q9Y4C8
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9Y4C8
PaxDbⁱ	Q9Y4C8
PeptideAtlas More...PeptideAtlasⁱ	Q9Y4C8
PRIDEⁱ	Q9Y4C8
ProteomicsDBⁱ	86163

2D gel databases

SWISS-2DPAGEⁱ	Q9Y4C8

SWISS-2DPAGEⁱ

Q9Y4C8

PTM databases

iPTMnetⁱ	Q9Y4C8
PhosphoSitePlusⁱ	Q9Y4C8

Expressionⁱ

Tissue specificityⁱ

Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level).1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000122965 Expressed in 158 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_RBM19
ExpressionAtlasⁱ	Q9Y4C8 baseline and differential
Genevisibleⁱ	Q9Y4C8 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA038860 HPA058732

HPAⁱ

HPA038860
HPA058732

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	115233, 118 interactors
IntActⁱ	Q9Y4C8, 4 interactors
Molecular INTeraction database More...MINTⁱ	Q9Y4C8
STRINGⁱ	9606.ENSP00000261741

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	295 – 299	Combined sources	5
Helixⁱ	307 – 314	Combined sources	8
Beta strandⁱ	320 – 326	Combined sources	7
Beta strandⁱ	332 – 339	Combined sources	8
Helixⁱ	343 – 351	Combined sources	9
Beta strandⁱ	354 – 357	Combined sources	4
Beta strandⁱ	360 – 368	Combined sources	9

Show more details

3D structure databases

ProteinModelPortalⁱ	Q9Y4C8
SMRⁱ	Q9Y4C8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q9Y4C8

EvolutionaryTraceⁱ

Q9Y4C8

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	2 – 79	RRM 1PROSITE-ProRule annotationAdd BLAST	78
Domainⁱ	294 – 369	RRM 2PROSITE-ProRule annotationAdd BLAST	76
Domainⁱ	402 – 480	RRM 3PROSITE-ProRule annotationAdd BLAST	79
Domainⁱ	587 – 659	RRM 4PROSITE-ProRule annotationAdd BLAST	73
Domainⁱ	730 – 811	RRM 5PROSITE-ProRule annotationAdd BLAST	82
Domainⁱ	832 – 912	RRM 6PROSITE-ProRule annotationAdd BLAST	81

Compositional bias

Feature key	Position(s)	DescriptionActions	Length
Compositional biasⁱ	225 – 232	Poly-Glu	8
Compositional biasⁱ	391 – 396	Poly-Glu	6
Compositional biasⁱ	714 – 725	Poly-GluAdd BLAST	12

Sequence similaritiesⁱ

Belongs to the RRM MRD1 family.Curated

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	KOG0110 Eukaryota ENOG410XQZ5 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00840000129953
HOGENOMⁱ	HOG000211156
HOVERGENⁱ	HBG055637
InParanoidⁱ	Q9Y4C8
KEGG Orthology (KO) More...KOⁱ	K14787
OMAⁱ	FCYVGFK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02IZ
PhylomeDBⁱ	Q9Y4C8
TreeFamⁱ	TF105725

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd12564 RRM1_RBM19, 1 hit cd12502 RRM2_RMB19, 1 hit cd12567 RRM3_RBM19, 1 hit cd12569 RRM4_RBM19, 1 hit cd12318 RRM5_RBM19_like, 1 hit cd12571 RRM6_RBM19, 1 hit
Gene3Dⁱ	3.30.70.330, 6 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR034419 RBM19_RRM3 IPR034420 RBM19_RRM4 IPR034423 RBM19_RRM5 IPR034421 RBM19_RRM6 IPR034418 RMB19_RRM1 IPR034417 RMB19_RRM2 IPR000504 RRM_dom IPR003954 RRM_dom_euk
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00076 RRM_1, 5 hits
SMARTⁱ	View protein in SMART SM00360 RRM, 6 hits SM00361 RRM_1, 2 hits
SUPFAMⁱ	SSF54928 SSF54928, 5 hits
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 6 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q9Y4C8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSRLIVKNLP NGMKEERFRQ LFAAFGTLTD CSLKFTKDGK FRKFGFIGFK 
        60         70         80         90        100
SEEEAQKAQK HFNKSFIDTS RITVEFCKSF GDPAKPRAWS KHAQKPSQPK 
       110        120        130        140        150
QPPKDSTTPE IKKDEKKKKV AGQLEKLKED TEFQEFLSVH QRRAQAATWA 
       160        170        180        190        200
NDGLDAEPSK GKSKPASDYL NFDSDSGQES EEEGAGEDLE EEASLEPKAA 
       210        220        230        240        250
VQKELSDMDY LKSKMVKAGS SSSSEEEESE DEAVHCDEGS EAEEEDSSAT 
       260        270        280        290        300
PVLQERDSKG AGQEQGMPAG KKRPPEARAE TEKPANQKEP TTCHTVKLRG 
       310        320        330        340        350
APFNVTEKNV MEFLAPLKPV AIRIVRNAHG NKTGYIFVDF SNEEEVKQAL 
       360        370        380        390        400
KCNREYMGGR YIEVFREKNV PTTKGAPKNT TKSWQGRILG ENEEEEDLAE 
       410        420        430        440        450
SGRLFVRNLP YTSTEEDLEK LFSKYGPLSE LHYPIDSLTK KPKGFAFITF 
       460        470        480        490        500
MFPEHAVKAY SEVDGQVFQG RMLHVLPSTI KKEASEDASA LGSSSYKKKK 
       510        520        530        540        550
EAQDKANSAS SHNWNTLFMG PNAVADAIAQ KYNATKSQVF DHETKGSVAV 
       560        570        580        590        600
RVALGETQLV QEVRRFLIDN GVSLDSFSQA AAERSKTVIL VKNLPAGTLA 
       610        620        630        640        650
AQLQETFGHF GSLGRVLLPE GGITAIVEFL EPLEARKAFR HLAYSKFHHV 
       660        670        680        690        700
PLYLEWAPVG VFSSTAPQKK KLQDTPSEPM EKDPAEPETV PDGETPEDEN 
       710        720        730        740        750
PTEEGADNSS AKMEEEEEEE EEEEESLPGC TLFIKNLNFD TTEEKLKEVF 
       760        770        780        790        800
SKVGTVKSCS ISKKKNKAGV LLSMGFGFVE YRKPEQAQKA LKQLQGHVVD 
       810        820        830        840        850
GHKLEVRISE RATKPAVTLA RKKQVPRKQT TSKILVRNIP FQAHSREIRE 
       860        870        880        890        900
LFSTFGELKT VRLPKKMTGT GTHRGFGFVD FLTKQDAKRA FNALCHSTHL 
       910        920        930        940        950
YGRRLVLEWA DSEVTLQALR RKTAAHFHEP PKKKRSVVLD EILEQLEGSD 
       960
SDSEEQTLQL

Length:960

Mass (Da):107,332

Last modified:October 5, 2010 - v3

Checksum:ⁱ28B6F37B18D7B9B1

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	H0YIL2	H0YIL2_HUMAN		Probable RNA-binding protein 19 Probable RNA-binding protein 19	RBM19	110	Annotation score:

Sequence cautionⁱ

The sequence BAA31657 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	141	Q → R in BAA31657 (PubMed:9734811).Curated	1
Sequence conflictⁱ	259	K → R in BAA31657 (PubMed:9734811).Curated	1
Sequence conflictⁱ	259	K → R in AAH06137 (PubMed:15489334).Curated	1
Sequence conflictⁱ	259	K → R in AAH04289 (PubMed:15489334).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_059822	602	Q → E4 PublicationsCorresponds to variant dbSNP:rs7299217Ensembl.	1
Natural variantⁱVAR_023114	609	H → R2 PublicationsCorresponds to variant dbSNP:rs2290789Ensembl.	1
Natural variantⁱVAR_023115	623	I → T2 PublicationsCorresponds to variant dbSNP:rs2290788Ensembl.	1
Natural variantⁱVAR_023116	665	T → A2 PublicationsCorresponds to variant dbSNP:rs2290787Ensembl.	1
Natural variantⁱVAR_057246	821	R → G. Corresponds to variant dbSNP:rs16943379Ensembl.	1
Natural variantⁱVAR_023117	921	R → Q1 PublicationCorresponds to variant dbSNP:rs2075387Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB014582 mRNA Translation: BAA31657.2 Different initiation. AL117547 mRNA Translation: CAB55987.1 AK291444 mRNA Translation: BAF84133.1 AK314606 mRNA Translation: BAG37176.1 AC009731 Genomic DNA No translation available. AC073863 Genomic DNA No translation available. AC090669 Genomic DNA No translation available. BC004289 mRNA Translation: AAH04289.1 BC006137 mRNA Translation: AAH06137.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS9172.1
PIRⁱ	T17297
NCBI Reference Sequences More...RefSeqⁱ	NP_001140170.1, NM_001146698.1 NP_001140171.1, NM_001146699.1 NP_057280.2, NM_016196.3
UniGeneⁱ	Hs.7482

Genome annotation databases

Ensemblⁱ	ENST00000261741; ENSP00000261741; ENSG00000122965 ENST00000392561; ENSP00000376344; ENSG00000122965 ENST00000545145; ENSP00000442053; ENSG00000122965
GeneIDⁱ	9904
KEGGⁱ	hsa:9904
UCSC genome browser More...UCSCⁱ	uc001tvm.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9Y4C8	Uncharacterized protein		PAPAN		998	UniRef90_Q9Y4C8
Uncharacterized protein		RHIBE		998
Uncharacterized protein		PANPA		961
Uncharacterized protein		MANLE		961
RBM19 isoform 1		PANTR		961
+33

Protein	Similar proteins		Species	Score	Length	Source
Q9Y4C8	Probable RNA-binding protein 19	)	MOUSE		952	UniRef50_Q8R3C6
RNA-binding motif protein 19		RAT		955
Putative RNA-binding protein 19		CRIGR		954
probable RNA-binding protein 19		MESAU		953
probable RNA-binding protein 19 isoform X1		ERIEU		961
+341

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB014582 mRNA Translation: BAA31657.2 Different initiation. AL117547 mRNA Translation: CAB55987.1 AK291444 mRNA Translation: BAF84133.1 AK314606 mRNA Translation: BAG37176.1 AC009731 Genomic DNA No translation available. AC073863 Genomic DNA No translation available. AC090669 Genomic DNA No translation available. BC004289 mRNA Translation: AAH04289.1 BC006137 mRNA Translation: AAH06137.1
CCDSⁱ	CCDS9172.1
PIRⁱ	T17297
RefSeqⁱ	NP_001140170.1, NM_001146698.1 NP_001140171.1, NM_001146699.1 NP_057280.2, NM_016196.3
UniGeneⁱ	Hs.7482

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2DGW	NMR	-	A	291-368	[»]
ProteinModelPortalⁱ	Q9Y4C8
SMRⁱ	Q9Y4C8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	115233, 118 interactors
IntActⁱ	Q9Y4C8, 4 interactors
MINTⁱ	Q9Y4C8
STRINGⁱ	9606.ENSP00000261741

PTM databases

iPTMnetⁱ	Q9Y4C8
PhosphoSitePlusⁱ	Q9Y4C8

Polymorphism and mutation databases

BioMutaⁱ	RBM19
DMDMⁱ	308153566

2D gel databases

SWISS-2DPAGEⁱ	Q9Y4C8

SWISS-2DPAGEⁱ

Q9Y4C8

Proteomic databases

EPDⁱ	Q9Y4C8
MaxQBⁱ	Q9Y4C8
PaxDbⁱ	Q9Y4C8
PeptideAtlasⁱ	Q9Y4C8
PRIDEⁱ	Q9Y4C8
ProteomicsDBⁱ	86163

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	9904
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000261741; ENSP00000261741; ENSG00000122965 ENST00000392561; ENSP00000376344; ENSG00000122965 ENST00000545145; ENSP00000442053; ENSG00000122965
GeneIDⁱ	9904
KEGGⁱ	hsa:9904
UCSCⁱ	uc001tvm.4 human

Organism-specific databases

CTDⁱ	9904
DisGeNETⁱ	9904
EuPathDBⁱ	HostDB:ENSG00000122965.10
GeneCardsⁱ	RBM19
HGNCⁱ	HGNC:29098 RBM19
HPAⁱ	HPA038860 HPA058732
MIMⁱ	616444 gene
neXtProtⁱ	NX_Q9Y4C8
OpenTargetsⁱ	ENSG00000122965
PharmGKBⁱ	PA134886784
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0110 Eukaryota ENOG410XQZ5 LUCA
GeneTreeⁱ	ENSGT00840000129953
HOGENOMⁱ	HOG000211156
HOVERGENⁱ	HBG055637
InParanoidⁱ	Q9Y4C8
KOⁱ	K14787
OMAⁱ	FCYVGFK
OrthoDBⁱ	EOG091G02IZ
PhylomeDBⁱ	Q9Y4C8
TreeFamⁱ	TF105725

Miscellaneous databases

ChiTaRSⁱ	RBM19 human
EvolutionaryTraceⁱ	Q9Y4C8
GeneWikiⁱ	RBM19
GenomeRNAiⁱ	9904
Protein Ontology More...PROⁱ	PR:Q9Y4C8
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000122965 Expressed in 158 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_RBM19
ExpressionAtlasⁱ	Q9Y4C8 baseline and differential
Genevisibleⁱ	Q9Y4C8 HS

Family and domain databases

CDDⁱ	cd12564 RRM1_RBM19, 1 hit cd12502 RRM2_RMB19, 1 hit cd12567 RRM3_RBM19, 1 hit cd12569 RRM4_RBM19, 1 hit cd12318 RRM5_RBM19_like, 1 hit cd12571 RRM6_RBM19, 1 hit
Gene3Dⁱ	3.30.70.330, 6 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR034419 RBM19_RRM3 IPR034420 RBM19_RRM4 IPR034423 RBM19_RRM5 IPR034421 RBM19_RRM6 IPR034418 RMB19_RRM1 IPR034417 RMB19_RRM2 IPR000504 RRM_dom IPR003954 RRM_dom_euk
Pfamⁱ	View protein in Pfam PF00076 RRM_1, 5 hits
SMARTⁱ	View protein in SMART SM00360 RRM, 6 hits SM00361 RRM_1, 2 hits
SUPFAMⁱ	SSF54928 SSF54928, 5 hits
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 6 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RBM19_HUMAN
Accessionⁱ	Q9Y4C8Primary (citable) accession number: Q9Y4C8 Secondary accession number(s): A8K5X9, Q9BPY6, Q9UFN5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
	Last sequence update:	October 5, 2010
	Last modified:	November 7, 2018
	This is version 168 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM

UniProtKB

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UniRef

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Supporting data

UniProtKB - Q9Y4C8 (RBM19_HUMAN)

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Probable RNA-binding protein 19

RBM19

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ