ZNF711

Functionⁱ

Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	383 – 408	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	26
Zinc fingerⁱ	414 – 436	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	476 – 499	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	505 – 527	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	533 – 556	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	562 – 584	C2H2-type 6; degeneratePROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	590 – 613	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	619 – 641	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	647 – 670	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	676 – 698	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	704 – 727	C2H2-type 11PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	733 – 755	C2H2-type 12PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

chromatin DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
metal ion binding Source: UniProtKB-KW
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sequence-specific DNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 20346720

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

positive regulation of transcription, DNA-templated
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 20346720

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-HSA-212436 Generic Transcription Pathway

Reactomeⁱ

R-HSA-212436 Generic Transcription Pathway

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 711 Alternative name(s): Zinc finger protein 6
Gene namesⁱ	Name:ZNF711 Synonyms:CMPX1, ZNF6
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome X

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000147180.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13128 ZNF711
MIMⁱ	314990 gene
neXtProtⁱ	NX_Q9Y462

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Mental retardation, X-linked 97 (MRX97)2 Publications

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.

Keywords - Diseaseⁱ

Mental retardation

Organism-specific databases

DisGeNET More...DisGeNETⁱ	7552
MalaCards human disease database More...MalaCardsⁱ	ZNF711
MIMⁱ	300803 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000147180
Orphanetⁱ	777 X-linked non-syndromic intellectual disability
PharmGKBⁱ	PA37702

Polymorphism and mutation databases

BioMutaⁱ	ZNF711
DMDMⁱ	308153535

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047329	1 – 761	Zinc finger protein 711Add BLAST		761

Amino acid modifications

Feature key	Position(s)	DescriptionActions
Cross-linkⁱ	224	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	235	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	296	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMⁱ

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbⁱ	Q9Y462
PeptideAtlas More...PeptideAtlasⁱ	Q9Y462
PRIDEⁱ	Q9Y462
ProteomicsDBⁱ	86107 86108 [Q9Y462-2] 86109 [Q9Y462-3]

PTM databases

iPTMnetⁱ	Q9Y462
PhosphoSitePlusⁱ	Q9Y462

Expressionⁱ

Tissue specificityⁱ

Expressed in neural tissues.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000147180 Expressed in 180 organ(s), highest expression level in neocortex
CleanExⁱ	HS_ZNF711
Genevisibleⁱ	Q9Y462 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA030654

HPAⁱ

HPA030654

Interactionⁱ

Subunit structureⁱ

Interacts with PHF8.1 Publication

Protein-protein interaction databases

BioGridⁱ	113384, 4 interactors
IntActⁱ	Q9Y462, 5 interactors
STRINGⁱ	9606.ENSP00000276123

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9Y462
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	383 – 408	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	26
Zinc fingerⁱ	414 – 436	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	476 – 499	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	505 – 527	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	533 – 556	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	562 – 584	C2H2-type 6; degeneratePROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	590 – 613	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	619 – 641	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	647 – 670	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	676 – 698	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	704 – 727	C2H2-type 11PROSITE-ProRule annotationAdd BLAST	24
Zinc fingerⁱ	733 – 755	C2H2-type 12PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063297
HOGENOMⁱ	HOG000231717
HOVERGENⁱ	HBG000337
InParanoidⁱ	Q9Y462
OMAⁱ	DKEPKLH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02CA
PhylomeDBⁱ	Q9Y462
TreeFamⁱ	TF335557

Family and domain databases

InterProⁱ	View protein in InterPro IPR006794 Transcrp_activ_Zfx/Zfy-dom IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 6 hits PF04704 Zfx_Zfy_act, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 12 hits
SUPFAMⁱ	SSF57667 SSF57667, 6 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 6 hits PS50157 ZINC_FINGER_C2H2_2, 11 hits

Sequences (3)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

Isoform 1 (identifier: Q9Y462-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDSGGGSLGL HTPDSRMAHT MIMQDFVAGM AGTAHIDGDH IVVSVPEAVL 
        60         70         80         90        100
VSDVVTDDGI TLDHGLAAEV VHGPDIITET DVVTEGVIVP EAVLEADVAI 
       110        120        130        140        150
EEDLEEDDGD HILTSELITE TVRVPEQVFV ADLVTGPNGH LEHVVQDCVS 
       160        170        180        190        200
GVDSPTMVSE EVLVTNSDTE TVIQAAGGVP GSTVTIKTED DDDDDVKSTS 
       210        220        230        240        250
EDYLMISLDD VGEKLEHMGN TPLKIGSDGS QEDAKEDGFG SEVIKVYIFK 
       260        270        280        290        300
AEAEDDVEIG GTEIVTESEY TSGHSVAGVL DQSRMQREKM VYMAVKDSSQ 
       310        320        330        340        350
EEDDIRDERR VSRRYEDCQA SGNTLDSALE SRSSTAAQYL QICDGINTNK 
       360        370        380        390        400
VLKQKAKKRR RGETRQWQTA VIIGPDGQPL TVYPCHICTK KFKSRGFLKR 
       410        420        430        440        450
HMKNHPDHLM RKKYQCTDCD FTTNKKVSFH NHLESHKLIN KVDKTHEFTE 
       460        470        480        490        500
YTRRYREASP LSSNKLILRD KEPKMHKCKY CDYETAEQGL LNRHLLAVHS 
       510        520        530        540        550
KNFPHVCVEC GKGFRHPSEL KKHMRTHTGE KPYQCQYCIF RCADQSNLKT 
       560        570        580        590        600
HIKSKHGNNL PYKCEHCPQA FGDERELQRH LDLFQGHKTH QCPHCDHKST 
       610        620        630        640        650
NSSDLKRHII SVHTKDFPHK CEVCDKGFHR PSELKKHSDI HKGRKIHQCR 
       660        670        680        690        700
HCDFKTSDPF ILSGHILSVH TKDQPLKCKR CKRGFRQQNE LKKHMKTHTG 
       710        720        730        740        750
RKIYQCEYCE YSTTDASGFK RHVISIHTKD YPHRCEFCKK GFRRPSEKNQ 
       760 
HIMRHHKEAL M

Length:761

Mass (Da):86,245

Last modified:October 5, 2010 - v2

Checksum:ⁱ8E95362C9F008B25

GO

Isoform 2 (identifier: Q9Y462-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
306-321: RDERRVSRRYEDCQAS → SCAEIADEVYMEVIVGEEEGTSLPEIQLEDSDVNKTVVPVVWAAAY

« Hide

        10         20         30         40         50
MDSGGGSLGL HTPDSRMAHT MIMQDFVAGM AGTAHIDGDH IVVSVPEAVL 
        60         70         80         90        100
VSDVVTDDGI TLDHGLAAEV VHGPDIITET DVVTEGVIVP EAVLEADVAI 
       110        120        130        140        150
EEDLEEDDGD HILTSELITE TVRVPEQVFV ADLVTGPNGH LEHVVQDCVS 
       160        170        180        190        200
GVDSPTMVSE EVLVTNSDTE TVIQAAGGVP GSTVTIKTED DDDDDVKSTS 
       210        220        230        240        250
EDYLMISLDD VGEKLEHMGN TPLKIGSDGS QEDAKEDGFG SEVIKVYIFK 
       260        270        280        290        300
AEAEDDVEIG GTEIVTESEY TSGHSVAGVL DQSRMQREKM VYMAVKDSSQ 
       310        320        330        340        350
EEDDISCAEI ADEVYMEVIV GEEEGTSLPE IQLEDSDVNK TVVPVVWAAA 
       360        370        380        390        400
YGNTLDSALE SRSSTAAQYL QICDGINTNK VLKQKAKKRR RGETRQWQTA 
       410        420        430        440        450
VIIGPDGQPL TVYPCHICTK KFKSRGFLKR HMKNHPDHLM RKKYQCTDCD 
       460        470        480        490        500
FTTNKKVSFH NHLESHKLIN KVDKTHEFTE YTRRYREASP LSSNKLILRD 
       510        520        530        540        550
KEPKMHKCKY CDYETAEQGL LNRHLLAVHS KNFPHVCVEC GKGFRHPSEL 
       560        570        580        590        600
KKHMRTHTGE KPYQCQYCIF RCADQSNLKT HIKSKHGNNL PYKCEHCPQA 
       610        620        630        640        650
FGDERELQRH LDLFQGHKTH QCPHCDHKST NSSDLKRHII SVHTKDFPHK 
       660        670        680        690        700
CEVCDKGFHR PSELKKHSDI HKGRKIHQCR HCDFKTSDPF ILSGHILSVH 
       710        720        730        740        750
TKDQPLKCKR CKRGFRQQNE LKKHMKTHTG RKIYQCEYCE YSTTDASGFK 
       760        770        780        790 
RHVISIHTKD YPHRCEFCKK GFRRPSEKNQ HIMRHHKEAL M

Show »

Length:791

Mass (Da):89,218

Checksum:ⁱ305920129ED16E27

GO

Isoform 3 (identifier: Q9Y462-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
306-306: R → SCAEIADEVYMEVIVGEEEGTSLPEIQLEDSDVNKTVVPVVWAAAYG

« Hide

        10         20         30         40         50
MDSGGGSLGL HTPDSRMAHT MIMQDFVAGM AGTAHIDGDH IVVSVPEAVL 
        60         70         80         90        100
VSDVVTDDGI TLDHGLAAEV VHGPDIITET DVVTEGVIVP EAVLEADVAI 
       110        120        130        140        150
EEDLEEDDGD HILTSELITE TVRVPEQVFV ADLVTGPNGH LEHVVQDCVS 
       160        170        180        190        200
GVDSPTMVSE EVLVTNSDTE TVIQAAGGVP GSTVTIKTED DDDDDVKSTS 
       210        220        230        240        250
EDYLMISLDD VGEKLEHMGN TPLKIGSDGS QEDAKEDGFG SEVIKVYIFK 
       260        270        280        290        300
AEAEDDVEIG GTEIVTESEY TSGHSVAGVL DQSRMQREKM VYMAVKDSSQ 
       310        320        330        340        350
EEDDISCAEI ADEVYMEVIV GEEEGTSLPE IQLEDSDVNK TVVPVVWAAA 
       360        370        380        390        400
YGDERRVSRR YEDCQASGNT LDSALESRSS TAAQYLQICD GINTNKVLKQ 
       410        420        430        440        450
KAKKRRRGET RQWQTAVIIG PDGQPLTVYP CHICTKKFKS RGFLKRHMKN 
       460        470        480        490        500
HPDHLMRKKY QCTDCDFTTN KKVSFHNHLE SHKLINKVDK THEFTEYTRR 
       510        520        530        540        550
YREASPLSSN KLILRDKEPK MHKCKYCDYE TAEQGLLNRH LLAVHSKNFP 
       560        570        580        590        600
HVCVECGKGF RHPSELKKHM RTHTGEKPYQ CQYCIFRCAD QSNLKTHIKS 
       610        620        630        640        650
KHGNNLPYKC EHCPQAFGDE RELQRHLDLF QGHKTHQCPH CDHKSTNSSD 
       660        670        680        690        700
LKRHIISVHT KDFPHKCEVC DKGFHRPSEL KKHSDIHKGR KIHQCRHCDF 
       710        720        730        740        750
KTSDPFILSG HILSVHTKDQ PLKCKRCKRG FRQQNELKKH MKTHTGRKIY 
       760        770        780        790        800
QCEYCEYSTT DASGFKRHVI SIHTKDYPHR CEFCKKGFRR PSEKNQHIMR 

HHKEALM

Note: No experimental confirmation available.

Show »

Length:807

Mass (Da):91,128

Checksum:ⁱ4B0FA684E635D721

GO

Sequence cautionⁱ

The sequence BAG61766 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence CAA39837 differs from that shown. Chimera.Curated

The sequence CAA39837 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	264 – 266	IVT → MSP in CAA39837 (PubMed:1923752).Curated	3
Sequence conflictⁱ	395	R → K in CAA39837 (PubMed:1923752).Curated	1
Sequence conflictⁱ	475 – 476	MH → TD in CAA39837 (PubMed:1923752).Curated	2
Sequence conflictⁱ	577	L → P in BAG61766 (PubMed:14702039).Curated	1
Sequence conflictⁱ	648	Q → T in CAA39837 (PubMed:1923752).Curated	1
Sequence conflictⁱ	666	I → L in CAA39837 (PubMed:1923752).Curated	1
Sequence conflictⁱ	680 – 682	RCK → GCT in CAA39837 (PubMed:1923752).Curated	3
Sequence conflictⁱ	703	I → S in CAA39837 (PubMed:1923752).Curated	1
Sequence conflictⁱ	739	K → N in CAA39837 (PubMed:1923752).Curated	1
Sequence conflictⁱ	754	R → K in CAA39837 (PubMed:1923752).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_062990	139	G → E in MRX97; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs367654949Ensembl.	1
Natural variantⁱVAR_062991	221	T → A1 PublicationCorresponds to variant dbSNP:rs148609081Ensembl.	1
Natural variantⁱVAR_078572	244	I → T in MRX97. 1 PublicationCorresponds to variant dbSNP:rs1060505033Ensembl.	1
Natural variantⁱVAR_062992	274	H → R in MRX97; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs777239465Ensembl.	1
Natural variantⁱVAR_062993	524	M → T1 PublicationCorresponds to variant dbSNP:rs368788919Ensembl.	1
Natural variantⁱVAR_062994	601	N → S in MRX97; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs760346140EnsemblClinVar.	1
Natural variantⁱVAR_062995	622	E → D in MRX97; unknown pathological significance. 1 Publication	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_016912	306 – 321	RDERR…DCQAS → SCAEIADEVYMEVIVGEEEG TSLPEIQLEDSDVNKTVVPV VWAAAY in isoform 2. CuratedAdd BLAST		16
Alternative sequenceⁱVSP_039887	306	R → SCAEIADEVYMEVIVGEEEG TSLPEIQLEDSDVNKTVVPV VWAAAYG in isoform 3. 1 Publication		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z82216 Genomic DNA No translation available. BC067294 mRNA Translation: AAH67294.1 AK299933 mRNA Translation: BAG61766.1 Different initiation. X56465 mRNA Translation: CAA39837.2 Sequence problems.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS35344.1 [Q9Y462-1] CCDS83481.1 [Q9Y462-3]
PIRⁱ	S25409
NCBI Reference Sequences More...RefSeqⁱ	NP_001317503.1, NM_001330574.1 [Q9Y462-3] NP_068838.3, NM_021998.4 [Q9Y462-1] XP_005262243.1, XM_005262186.2 [Q9Y462-3] XP_005262244.1, XM_005262187.1 [Q9Y462-3] XP_005262245.1, XM_005262188.1 [Q9Y462-3] XP_005262246.1, XM_005262189.2 [Q9Y462-1] XP_011529326.1, XM_011531024.1 [Q9Y462-3] XP_011529328.1, XM_011531026.1 [Q9Y462-1] XP_016885294.1, XM_017029805.1 [Q9Y462-3] XP_016885295.1, XM_017029806.1 XP_016885296.1, XM_017029807.1 [Q9Y462-1] XP_016885297.1, XM_017029808.1 [Q9Y462-1] XP_016885298.1, XM_017029809.1 [Q9Y462-1]
UniGeneⁱ	Hs.326801

Genome annotation databases

Ensemblⁱ	ENST00000276123; ENSP00000276123; ENSG00000147180 [Q9Y462-1] ENST00000360700; ENSP00000353922; ENSG00000147180 [Q9Y462-3] ENST00000373165; ENSP00000362260; ENSG00000147180 [Q9Y462-1]
GeneIDⁱ	7552
KEGGⁱ	hsa:7552
UCSC genome browser More...UCSCⁱ	uc004eeo.4 human [Q9Y462-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9Y462	ZNF711 isoform 1		PANTR		761	UniRef100_Q9Y462
Uncharacterized protein		PANPA		761
Zinc finger protein 711		GORGO		761
Q9Y462-3	ZNF711 isoform 3		PANTR		807	UniRef100_H2RC05
Uncharacterized protein		PANPA		807
Zinc finger protein 711		GORGO		807

Protein	Similar proteins		Species	Score	Length	Source
Q9Y462	Zinc finger protein 711		MOUSE		761	UniRef90_Q9Y462
ZNF711 isoform 1		PANTR		761
Uncharacterized protein		PANPA		761
Zinc finger protein 711		GORGO		761
zinc finger protein 711 isoform X1		ERIEU		770
+112
Q9Y462-2	zinc finger protein 711 isoform X2		Enhydra lutris kenyoni		791	UniRef90_Q9Y462-2
Uncharacterized protein		RHIBE		775
Zinc finger protein		CRIGR		774
Uncharacterized protein (Fragment)		AILME		768
Zinc finger protein 6 isoform 3-like protein		CAMFR		764
+12
Q9Y462-3	Zinc finger protein 711		FELCA		812	UniRef90_M3WIN0
Zinc finger protein 711		HETGA		819
zinc finger protein 711 isoform X1		Yangtze finless porpoise		815
zinc finger protein 711 isoform X1		DELLE		814
zinc finger protein 711 isoform X1		PHYCD		814
+90

Protein	Similar proteins		Species	Score	Length	Source
Q9Y462	Zinc finger protein 711		MOUSE		761	UniRef50_Q9Y462
Zinc finger protein 711		DANRE		761
ZNF711 isoform 1		PANTR		761
Uncharacterized protein		PANPA		761
Zinc finger protein 711		GORGO		761
+366
Q9Y462-3	Zinc finger X-chromosomal protein		MOUSE		799	UniRef50_P17012
Zinc finger X-chromosomal protein		HUMAN		805
Zinc finger Y-chromosomal protein		PANTR		801
Zinc finger Y-chromosomal protein		GORGO		801
Zinc finger Y-chromosomal protein		BOVIN		801
+1016

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z82216 Genomic DNA No translation available. BC067294 mRNA Translation: AAH67294.1 AK299933 mRNA Translation: BAG61766.1 Different initiation. X56465 mRNA Translation: CAA39837.2 Sequence problems.
CCDSⁱ	CCDS35344.1 [Q9Y462-1] CCDS83481.1 [Q9Y462-3]
PIRⁱ	S25409
RefSeqⁱ	NP_001317503.1, NM_001330574.1 [Q9Y462-3] NP_068838.3, NM_021998.4 [Q9Y462-1] XP_005262243.1, XM_005262186.2 [Q9Y462-3] XP_005262244.1, XM_005262187.1 [Q9Y462-3] XP_005262245.1, XM_005262188.1 [Q9Y462-3] XP_005262246.1, XM_005262189.2 [Q9Y462-1] XP_011529326.1, XM_011531024.1 [Q9Y462-3] XP_011529328.1, XM_011531026.1 [Q9Y462-1] XP_016885294.1, XM_017029805.1 [Q9Y462-3] XP_016885295.1, XM_017029806.1 XP_016885296.1, XM_017029807.1 [Q9Y462-1] XP_016885297.1, XM_017029808.1 [Q9Y462-1] XP_016885298.1, XM_017029809.1 [Q9Y462-1]
UniGeneⁱ	Hs.326801

3D structure databases

ProteinModelPortalⁱ	Q9Y462
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	113384, 4 interactors
IntActⁱ	Q9Y462, 5 interactors
STRINGⁱ	9606.ENSP00000276123

PTM databases

iPTMnetⁱ	Q9Y462
PhosphoSitePlusⁱ	Q9Y462

Polymorphism and mutation databases

BioMutaⁱ	ZNF711
DMDMⁱ	308153535

Proteomic databases

PaxDbⁱ	Q9Y462
PeptideAtlasⁱ	Q9Y462
PRIDEⁱ	Q9Y462
ProteomicsDBⁱ	86107 86108 [Q9Y462-2] 86109 [Q9Y462-3]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000276123; ENSP00000276123; ENSG00000147180 [Q9Y462-1] ENST00000360700; ENSP00000353922; ENSG00000147180 [Q9Y462-3] ENST00000373165; ENSP00000362260; ENSG00000147180 [Q9Y462-1]
GeneIDⁱ	7552
KEGGⁱ	hsa:7552
UCSCⁱ	uc004eeo.4 human [Q9Y462-1]

Organism-specific databases

CTDⁱ	7552
DisGeNETⁱ	7552
EuPathDBⁱ	HostDB:ENSG00000147180.16
GeneCardsⁱ	ZNF711
HGNCⁱ	HGNC:13128 ZNF711
HPAⁱ	HPA030654
MalaCardsⁱ	ZNF711
MIMⁱ	300803 phenotype 314990 gene
neXtProtⁱ	NX_Q9Y462
OpenTargetsⁱ	ENSG00000147180
Orphanetⁱ	777 X-linked non-syndromic intellectual disability
PharmGKBⁱ	PA37702
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00530000063297
HOGENOMⁱ	HOG000231717
HOVERGENⁱ	HBG000337
InParanoidⁱ	Q9Y462
OMAⁱ	DKEPKLH
OrthoDBⁱ	EOG091G02CA
PhylomeDBⁱ	Q9Y462
TreeFamⁱ	TF335557

Enzyme and pathway databases

Reactomeⁱ	R-HSA-212436 Generic Transcription Pathway

Reactomeⁱ

R-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRSⁱ	ZNF711 human
GenomeRNAiⁱ	7552
Protein Ontology More...PROⁱ	PR:Q9Y462
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000147180 Expressed in 180 organ(s), highest expression level in neocortex
CleanExⁱ	HS_ZNF711
Genevisibleⁱ	Q9Y462 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR006794 Transcrp_activ_Zfx/Zfy-dom IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 6 hits PF04704 Zfx_Zfy_act, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 12 hits
SUPFAMⁱ	SSF57667 SSF57667, 6 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 6 hits PS50157 ZINC_FINGER_C2H2_2, 11 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZN711_HUMAN
Accessionⁱ	Q9Y462Primary (citable) accession number: Q9Y462 Secondary accession number(s): B4DSV4, Q6NX42, Q9Y4J6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	September 19, 2002
	Last sequence update:	October 5, 2010
	Last modified:	November 7, 2018
	This is version 164 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM

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UniProtKB - Q9Y462 (ZN711_HUMAN)

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Zinc finger protein 711

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

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Zinc finger

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Phylogenomic databases

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<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ