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Entry version 140 (08 May 2019)
Sequence version 2 (10 Jan 2006)
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Protein

C2 domain-containing protein 2

Gene

C2CD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C2 domain-containing protein 2
Alternative name(s):
Transmembrane protein 24-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C2CD2
Synonyms:C21orf25, C21orf258, TMEM24L
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1266 C2CD2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617581 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y426

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei13 – 33HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
25966

Open Targets

More...
OpenTargetsi
ENSG00000157617

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162379018

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C2CD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
85681926

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000453861 – 696C2 domain-containing protein 2Add BLAST696

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei60PhosphoserineBy similarity1
Modified residuei435PhosphoserineCombined sources1
Modified residuei441PhosphoserineCombined sources1
Modified residuei445PhosphothreonineCombined sources1
Modified residuei581PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y426

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y426

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9Y426

PeptideAtlas

More...
PeptideAtlasi
Q9Y426

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y426

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86093
86094 [Q9Y426-2]
86095 [Q9Y426-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y426

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y426

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000157617 Expressed in 214 organ(s), highest expression level in adrenal gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y426 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y426 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA030922
HPA030924

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117454, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y426, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000369853

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 242SMP-LBDCuratedAdd BLAST192
Domaini270 – 362C2PROSITE-ProRule annotationAdd BLAST93

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IGE7 Eukaryota
ENOG4112CMM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063764

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000008704

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y426

Identification of Orthologs from Complete Genome Data

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OMAi
RHQQKDP

Database of Orthologous Groups

More...
OrthoDBi
890695at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y426

TreeFam database of animal gene trees

More...
TreeFami
TF331604

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR039934 C2CD2/C2CD2L
IPR040885 SMP_C2CD2L

The PANTHER Classification System

More...
PANTHERi
PTHR21119 PTHR21119, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168 C2, 1 hit
PF18696 SMP_C2CD2L, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y426-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAMARLGSWL GEAQWLALVS LFVAALATVG LYLAQWALAR ARPQPQRRAV
60 70 80 90 100
EPGEGPRPGS DALLSWILTL GSWRSQWQAA WVTALNEEAE RKGGPPFLSF
110 120 130 140 150
EEDPRQQALE LVVQEVSSVL RSAEEKVVVC HVVGQAIQFL VSETPALGAG
160 170 180 190 200
CRLYDMRLSP FHLQLEFHMK EKREDLQISW SFISVPEMAV NIQPKALGED
210 220 230 240 250
QVAETSAMSD VLKDILKHLA GSASPSVVLI TKPTTVKEAQ NLQCAASTAQ
260 270 280 290 300
ESCPPKPPRA HELKLLVRNI HVLLLSEPGA SGHINAVCVV QLNDPVQRFS
310 320 330 340 350
STLTKNTPDL MWEEEFTFEL NAKSKELHLQ ISEAGRSSEG LLATATVPLD
360 370 380 390 400
LFKKQPSGPQ SFTLTSGSAC GSSVLGSVTA EFSYMEPGEL KSWPIPPPVP
410 420 430 440 450
AAKIEKDRTV MPCGTVVTTV TAVKTKPRVD VGRASPLSSD SPVKTPIKVK
460 470 480 490 500
VIEKDISVQA IACRSAPVSK TLSSSDTELL VLNGSDPVAE VAIRQLSESS
510 520 530 540 550
KLKLKSPRKK STIIISGISK TSLSQDHDAA LMQGYTASVD STHQEDAPSH
560 570 580 590 600
PERAAASAPP EEAESAQASL APKPQEDELD SWDLEKEPQA AAWSSQVLLD
610 620 630 640 650
PDGDELSESS MSVLEPGTAK KHKGGILRKG AKLFFRRRHQ QKDPGMSQSH
660 670 680 690
NDLVFLEQPE GSRRKGITLT RILNKKLLSR HRNKNTMNGA PVEPCT
Length:696
Mass (Da):75,533
Last modified:January 10, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73F757C8608061F9
GO
Isoform 2 (identifier: Q9Y426-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-155: Missing.

Show »
Length:541
Mass (Da):58,613
Checksum:i64DD4953464F1942
GO
Isoform 3 (identifier: Q9Y426-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     521-525: Missing.

Note: No experimental confirmation available.
Show »
Length:691
Mass (Da):75,017
Checksum:i53B21D413BF4EC76
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BZB0H7BZB0_HUMAN
C2 domain-containing protein 2
C2CD2
182Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA95528 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAH10536 differs from that shown. Intron retention.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti460A → T in CAH10536 (PubMed:17974005).Curated1
Sequence conflicti639H → R in CAH10536 (PubMed:17974005).Curated1
Sequence conflicti679S → P in CAH10536 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050928211V → A. Corresponds to variant dbSNP:rs2839421Ensembl.1
Natural variantiVAR_050929618T → A. Corresponds to variant dbSNP:rs9981024Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0410711 – 155Missing in isoform 2. 1 PublicationAdd BLAST155
Alternative sequenceiVSP_041072521 – 525Missing in isoform 3. 1 Publication5

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB047784 mRNA Translation: BAD74068.1
AB047785 mRNA Translation: BAD74069.1
AL050173 mRNA Translation: CAB43307.1
AL833323 mRNA No translation available.
CR627455 mRNA Translation: CAH10536.1 Sequence problems.
AP001745 Genomic DNA Translation: BAA95528.1 Sequence problems.
AP001619 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13677.1 [Q9Y426-2]
CCDS42933.1 [Q9Y426-1]

Protein sequence database of the Protein Information Resource

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PIRi
T08793

NCBI Reference Sequences

More...
RefSeqi
NP_056315.1, NM_015500.1 [Q9Y426-1]
NP_950251.1, NM_199050.2 [Q9Y426-2]
XP_005261166.1, XM_005261109.4 [Q9Y426-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000329623; ENSP00000329302; ENSG00000157617 [Q9Y426-2]
ENST00000380486; ENSP00000369853; ENSG00000157617 [Q9Y426-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
25966

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:25966

UCSC genome browser

More...
UCSCi
uc002yzv.4 human [Q9Y426-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB047784 mRNA Translation: BAD74068.1
AB047785 mRNA Translation: BAD74069.1
AL050173 mRNA Translation: CAB43307.1
AL833323 mRNA No translation available.
CR627455 mRNA Translation: CAH10536.1 Sequence problems.
AP001745 Genomic DNA Translation: BAA95528.1 Sequence problems.
AP001619 Genomic DNA No translation available.
CCDSiCCDS13677.1 [Q9Y426-2]
CCDS42933.1 [Q9Y426-1]
PIRiT08793
RefSeqiNP_056315.1, NM_015500.1 [Q9Y426-1]
NP_950251.1, NM_199050.2 [Q9Y426-2]
XP_005261166.1, XM_005261109.4 [Q9Y426-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi117454, 7 interactors
IntActiQ9Y426, 1 interactor
STRINGi9606.ENSP00000369853

PTM databases

iPTMnetiQ9Y426
PhosphoSitePlusiQ9Y426

Polymorphism and mutation databases

BioMutaiC2CD2
DMDMi85681926

Proteomic databases

EPDiQ9Y426
jPOSTiQ9Y426
PaxDbiQ9Y426
PeptideAtlasiQ9Y426
PRIDEiQ9Y426
ProteomicsDBi86093
86094 [Q9Y426-2]
86095 [Q9Y426-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329623; ENSP00000329302; ENSG00000157617 [Q9Y426-2]
ENST00000380486; ENSP00000369853; ENSG00000157617 [Q9Y426-1]
GeneIDi25966
KEGGihsa:25966
UCSCiuc002yzv.4 human [Q9Y426-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25966
DisGeNETi25966

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C2CD2
HGNCiHGNC:1266 C2CD2
HPAiHPA030922
HPA030924
MIMi617581 gene
neXtProtiNX_Q9Y426
OpenTargetsiENSG00000157617
PharmGKBiPA162379018

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGE7 Eukaryota
ENOG4112CMM LUCA
GeneTreeiENSGT00530000063764
HOGENOMiHOG000008704
InParanoidiQ9Y426
OMAiRHQQKDP
OrthoDBi890695at2759
PhylomeDBiQ9Y426
TreeFamiTF331604

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
25966

Protein Ontology

More...
PROi
PR:Q9Y426

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000157617 Expressed in 214 organ(s), highest expression level in adrenal gland
ExpressionAtlasiQ9Y426 baseline and differential
GenevisibleiQ9Y426 HS

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR039934 C2CD2/C2CD2L
IPR040885 SMP_C2CD2L
PANTHERiPTHR21119 PTHR21119, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF18696 SMP_C2CD2L, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC2CD2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y426
Secondary accession number(s): Q5R2V7, Q6AHX8, Q9NSE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 10, 2006
Last modified: May 8, 2019
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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