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Entry version 148 (07 Apr 2021)
Sequence version 1 (01 Nov 1999)
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Protein

Zinc finger protein 330

Gene

ZNF330

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri42 – 58C4-type 1Sequence analysisAdd BLAST17
Zinc fingeri67 – 104C4-type 2Sequence analysisAdd BLAST38
Zinc fingeri129 – 149C4-type 3Sequence analysisAdd BLAST21
Zinc fingeri175 – 189C4-type 4Sequence analysisAdd BLAST15

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • metal ion binding Source: UniProtKB
  • zinc ion binding Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9Y3S2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 330
Alternative name(s):
Nucleolar autoantigen 36
Nucleolar cysteine-rich protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF330
Synonyms:NOA36
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:15462, ZNF330

Online Mendelian Inheritance in Man (OMIM)

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MIMi
609550, gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q9Y3S2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000109445.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Centromere, Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000109445

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134925405

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y3S2, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF330

Domain mapping of disease mutations (DMDM)

More...
DMDMi
51702204

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000665901 – 320Zinc finger protein 330Add BLAST320

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei291PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y3S2

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9Y3S2

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9Y3S2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y3S2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y3S2

PeptideAtlas

More...
PeptideAtlasi
Q9Y3S2

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y3S2

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
86075

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y3S2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y3S2

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9Y3S2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. Higher expression seen in heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000109445, Expressed in amniotic fluid and 250 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9Y3S2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y3S2, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000109445, Tissue enhanced (heart)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q9Y3S2
With#Exp.IntAct
ADAMTSL4 - isoform 3 [Q6UY14-3]3EBI-373456,EBI-10173507
CCN3 [P48745]3EBI-373456,EBI-3904822
CFP [P27918]3EBI-373456,EBI-9038570
CHIC2 [Q9UKJ5]3EBI-373456,EBI-741528
CNNM3 [Q8NE01]3EBI-373456,EBI-741032
CREB5 - isoform 3 [Q02930-3]3EBI-373456,EBI-10192698
CYSRT1 [A8MQ03]3EBI-373456,EBI-3867333
KLF15 [Q9UIH9]5EBI-373456,EBI-2796400
KRTAP1-1 [Q07627]3EBI-373456,EBI-11959885
KRTAP10-8 [P60410]3EBI-373456,EBI-10171774
KRTAP13-3 [Q3SY46]3EBI-373456,EBI-10241252
KRTAP5-7 [Q6L8G8]3EBI-373456,EBI-11987425
MDFI [Q99750]3EBI-373456,EBI-724076
MEOX2 [Q6FHY5]3EBI-373456,EBI-16439278
NDUFB7 [P17568]3EBI-373456,EBI-1246238
NOTCH2NLC [P0DPK4]3EBI-373456,EBI-22310682
NR4A3 [Q92570]3EBI-373456,EBI-13644623
OTX1 [P32242]3EBI-373456,EBI-740446
PBX4 [Q9BYU1]3EBI-373456,EBI-10302990
PICK1 [Q9NRD5]3EBI-373456,EBI-79165
RBAK [Q9NYW8]3EBI-373456,EBI-1210429
RSPO2 - isoform 2 [Q6UXX9-2]3EBI-373456,EBI-12009390
RSPO4 [Q2I0M5]3EBI-373456,EBI-12821217
RWDD4 [Q6NW29]6EBI-373456,EBI-743971
SPATA3 [A0A024R4B0]3EBI-373456,EBI-14123856
SPRY1 [O43609]3EBI-373456,EBI-3866665
STK16 [O75716]6EBI-373456,EBI-749295
STX19 [Q8N4C7]3EBI-373456,EBI-8484990
SUFU [Q9UMX1]3EBI-373456,EBI-740595
TCL1B [O95988]6EBI-373456,EBI-727338
TLE5 - isoform 2 [Q08117-2]5EBI-373456,EBI-11741437
TRIM42 [Q8IWZ5]3EBI-373456,EBI-5235829
ZBTB42 [B2RXF5]3EBI-373456,EBI-12287587
ZNF23 [P17027]3EBI-373456,EBI-5657766
ZNF250 - isoform 3 [P15622-3]3EBI-373456,EBI-10177272
ZNF408 [Q9H9D4]4EBI-373456,EBI-347633
ZNF426 [Q9BUY5]3EBI-373456,EBI-743265
ZNF440 [Q8IYI8]3EBI-373456,EBI-726439
ZNF460 [Q14592]3EBI-373456,EBI-2555738
ZNF547 [Q8IVP9]5EBI-373456,EBI-12895421
ZNF587 [Q96SQ5]3EBI-373456,EBI-6427977
ZNF655 [Q8N720]3EBI-373456,EBI-625509
ZNF664 [Q8N3J9]3EBI-373456,EBI-2799450
ZNF669 [Q96BR6]3EBI-373456,EBI-12006574
ZNF683 [Q8IZ20]3EBI-373456,EBI-12005952
ZNF688 [P0C7X2]3EBI-373456,EBI-4395732
ZNF764 [Q96H86]3EBI-373456,EBI-745775
ZNF768 [Q9H5H4]3EBI-373456,EBI-1210580
ZNF837 [Q96EG3]6EBI-373456,EBI-11962574

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
118131, 54 interactors

Protein interaction database and analysis system

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IntActi
Q9Y3S2, 51 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000262990

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y3S2, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi3 – 11Nuclear localization signalSequence analysis9

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi269 – 286Asp/Glu-rich (acidic)Add BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NOA36 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri42 – 58C4-type 1Sequence analysisAdd BLAST17
Zinc fingeri67 – 104C4-type 2Sequence analysisAdd BLAST38
Zinc fingeri129 – 149C4-type 3Sequence analysisAdd BLAST21
Zinc fingeri175 – 189C4-type 4Sequence analysisAdd BLAST15

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502QRJT, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00390000017043

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9Y3S2

Identification of Orthologs from Complete Genome Data

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OMAi
THACICP

Database of Orthologous Groups

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OrthoDBi
935225at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y3S2

TreeFam database of animal gene trees

More...
TreeFami
TF323303

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010531, NOA36

The PANTHER Classification System

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PANTHERi
PTHR13214, PTHR13214, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06524, NOA36, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q9Y3S2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKKKTGARK KAENRREREK QLRASRSTID LAKHPCNASM ECDKCQRRQK
60 70 80 90 100
NRAFCYFCNS VQKLPICAQC GKTKCMMKSS DCVIKHAGVY STGLAMVGAI
110 120 130 140 150
CDFCEAWVCH GRKCLSTHAC ACPLTDAECV ECERGVWDHG GRIFSCSFCH
160 170 180 190 200
NFLCEDDQFE HQASCQVLEA ETFKCVSCNR LGQHSCLRCK ACFCDDHTRS
210 220 230 240 250
KVFKQEKGKQ PPCPKCGHET QETKDLSMST RSLKFGRQTG GEEGDGASGY
260 270 280 290 300
DAYWKNLSSD KYGDTSYHDE EEDEYEAEDD EEEEDEGRKD SDTESSDLFT
310 320
NLNLGRTYAS GYAHYEEQEN
Length:320
Mass (Da):36,201
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC7F03EE70BF8FD1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RBR7D6RBR7_HUMAN
Nucleolar autoantigen 36
ZNF330
229Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R8Y9D6R8Y9_HUMAN
Nucleolar autoantigen 36
ZNF330
153Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9C8D6R9C8_HUMAN
Nucleolar autoantigen 36
ZNF330
139Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RBS7D6RBS7_HUMAN
Nucleolar autoantigen 36
ZNF330
35Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RCK7D6RCK7_HUMAN
Nucleolar autoantigen 36
ZNF330
77Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05150028T → A. Corresponds to variant dbSNP:rs35353789Ensembl.1
Natural variantiVAR_051501298L → M. Corresponds to variant dbSNP:rs34631212Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ006591 mRNA Translation: CAB43112.1
AJ404873 AJ404880 Genomic DNA Translation: CAC18679.1
AK315463 mRNA Translation: BAG37850.1
CH471056 Genomic DNA Translation: EAX05089.1
BC004421 mRNA Translation: AAH04421.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS3754.1

NCBI Reference Sequences

More...
RefSeqi
NP_001278931.1, NM_001292002.1
NP_055302.1, NM_014487.5
XP_016863522.1, XM_017008033.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000262990; ENSP00000262990; ENSG00000109445

Database of genes from NCBI RefSeq genomes

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GeneIDi
27309

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27309

UCSC genome browser

More...
UCSCi
uc003iiq.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ006591 mRNA Translation: CAB43112.1
AJ404873 AJ404880 Genomic DNA Translation: CAC18679.1
AK315463 mRNA Translation: BAG37850.1
CH471056 Genomic DNA Translation: EAX05089.1
BC004421 mRNA Translation: AAH04421.1
CCDSiCCDS3754.1
RefSeqiNP_001278931.1, NM_001292002.1
NP_055302.1, NM_014487.5
XP_016863522.1, XM_017008033.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
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Protein-protein interaction databases

BioGRIDi118131, 54 interactors
IntActiQ9Y3S2, 51 interactors
STRINGi9606.ENSP00000262990

PTM databases

iPTMnetiQ9Y3S2
PhosphoSitePlusiQ9Y3S2
SwissPalmiQ9Y3S2

Genetic variation databases

BioMutaiZNF330
DMDMi51702204

Proteomic databases

EPDiQ9Y3S2
jPOSTiQ9Y3S2
MassIVEiQ9Y3S2
MaxQBiQ9Y3S2
PaxDbiQ9Y3S2
PeptideAtlasiQ9Y3S2
PRIDEiQ9Y3S2
ProteomicsDBi86075

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
2840, 37 antibodies

The DNASU plasmid repository

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DNASUi
27309

Genome annotation databases

EnsembliENST00000262990; ENSP00000262990; ENSG00000109445
GeneIDi27309
KEGGihsa:27309
UCSCiuc003iiq.5, human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
27309

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF330
HGNCiHGNC:15462, ZNF330
HPAiENSG00000109445, Tissue enhanced (heart)
MIMi609550, gene
neXtProtiNX_Q9Y3S2
OpenTargetsiENSG00000109445
PharmGKBiPA134925405
VEuPathDBiHostDB:ENSG00000109445.10

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502QRJT, Eukaryota
GeneTreeiENSGT00390000017043
InParanoidiQ9Y3S2
OMAiTHACICP
OrthoDBi935225at2759
PhylomeDBiQ9Y3S2
TreeFamiTF323303

Enzyme and pathway databases

PathwayCommonsiQ9Y3S2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
27309, 11 hits in 997 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF330, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZNF330

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
27309
PharosiQ9Y3S2, Tdark

Protein Ontology

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PROi
PR:Q9Y3S2
RNActiQ9Y3S2, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000109445, Expressed in amniotic fluid and 250 other tissues
ExpressionAtlasiQ9Y3S2, baseline and differential
GenevisibleiQ9Y3S2, HS

Family and domain databases

InterProiView protein in InterPro
IPR010531, NOA36
PANTHERiPTHR13214, PTHR13214, 1 hit
PfamiView protein in Pfam
PF06524, NOA36, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN330_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y3S2
Secondary accession number(s): B2RDA3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: November 1, 1999
Last modified: April 7, 2021
This is version 148 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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