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Entry version 166 (07 Apr 2021)
Sequence version 1 (01 Nov 1999)
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Protein

RING finger protein 11

Gene

RNF11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates 'Lys-63' polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri99 – 140RING-typePROSITE-ProRule annotationAdd BLAST42

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

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PathwayCommonsi
Q9Y3C5

SIGNOR Signaling Network Open Resource

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SIGNORi
Q9Y3C5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RING finger protein 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RNF11
ORF Names:CGI-123
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:10056, RNF11

Online Mendelian Inheritance in Man (OMIM)

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MIMi
612598, gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q9Y3C5

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
HostDB:ENSG00000123091.4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Endosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2G → A: Loss of myristoylation. Change in subcellular location: Becomes diffused throughout the cytosol. Strong reduction of ubiquitination. Reduced efficiency of ITCH-binding. 1 Publication1
Mutagenesisi4C → S: Change in subcellular location: Becomes partially cytosolic and retained in association with the Golgi apparatus. Partial reduction of ubiquitination. 1 Publication1
Mutagenesisi12D → A: Loss of GGA1-binding. 1 Publication1
Mutagenesisi15L → A: Loss of GGA1-binding. 1 Publication1
Mutagenesisi16L → A: Loss of GGA1-binding. 1 Publication1
Mutagenesisi40Y → A: Loss of ITCH-, SMURF2- and WWP1-binding. Partial loss of ubiquitination by ITCH. No effect on STAMBP-binding; when associated with S-99 and S-102. Persistent TNF-mediated NFKBIA phosphorylation. Loss of stimulus-dependent complex formation with TAX1BP1, TNFAIP3 and RIPK1. 5 Publications1
Mutagenesisi99C → S: No effect on STAMBP- and SMURF2-binding; when associated with S-102. Persistent TNF-mediated NFKBIA phosphorylation. No effect on STAMBP-binding; when associated with A-40 and S-102. No effect on ubiquitination by ITCH; when associated with S-102. Loss of stimulus-dependent complex formation with TAX1BP1, TNFAIP3 and RIPK1. 4 Publications1
Mutagenesisi102C → S: No effect on STAMBP- and SMURF2-binding; when associated with S-99. No effect on ubiquitination by ITCH; when associated with S-102. No effect on STAMBP-binding; when associated with A-40 and S-99. 3 Publications1
Mutagenesisi103M → A or G: Loss of UBE2N-binding. No gain of UBE2L3-binding. 1 Publication1
Mutagenesisi103M → L: No effect on UBE2N-binding. No gain of UBE2L3-binding; when associated with L-127 and L-128. 1 Publication1
Mutagenesisi103M → V: No effect on UBE2N-binding. Gain of UBE2L3-binding. 1 Publication1
Mutagenesisi127D → L: No effect on UBE2N-binding. No gain of UBE2L3-binding; when associated with L-128. 1 Publication1
Mutagenesisi128D → L: No effect on UBE2N-binding. No gain of UBE2L3-binding. 1 Publication1
Mutagenesisi135T → E: Loss of phosphorylation and of 14-3-3-binding. 1 Publication1

Organism-specific databases

DisGeNET

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DisGeNETi
26994

Open Targets

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OpenTargetsi
ENSG00000123091

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA34420

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

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Pharosi
Q9Y3C5, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
RNF11

Domain mapping of disease mutations (DMDM)

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DMDMi
21362884

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000560502 – 154RING finger protein 11Add BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2N-myristoyl glycine2 Publications1
Lipidationi4S-palmitoyl cysteine1 Publication1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei14PhosphoserineCombined sources1
Modified residuei25PhosphoserineBy similarity1
Modified residuei135Phosphothreonine; by PKB/AKT11 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ubiquitinated in the presence of ITCH, or SMURF2, and UBE2D1, as well as WWP1.2 Publications
Phosphorylation by PKB/AKT1 may accelerate degradation by the proteasome.1 Publication
Acylation at both Gly-2 and Cys-4 is required for proper localization to the endosomes.1 Publication

Keywords - PTMi

Lipoprotein, Myristate, Palmitate, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9Y3C5

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9Y3C5

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9Y3C5

MaxQB - The MaxQuant DataBase

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MaxQBi
Q9Y3C5

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9Y3C5

PeptideAtlas

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PeptideAtlasi
Q9Y3C5

PRoteomics IDEntifications database

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PRIDEi
Q9Y3C5

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
86014

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q9Y3C5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q9Y3C5

SwissPalm database of S-palmitoylation events

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SwissPalmi
Q9Y3C5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at low levels in the lung, liver, kidney, pancreas, spleen, prostate, thymus, ovary, small intestine, colon, and peripheral blood lymphocytes, and, at intermediate levels, in the testis, heart, brain and placenta. Highest expression in the skeletal muscle. In the brain, expressed at different levels in several regions: high levels in the amygdala, moderate in the hippocampus and thalamus, low in the caudate and extremely low levels in the corpus callosum (at protein level). Restricted to neurons, enriched in somatodendritic compartments and excluded from white matter (at protein level). In substantia nigra, present in cell bodies and processes of dopaminergic and nondopaminergic cells (at protein level). In Parkinson disease, sequestered in Lewy bodies and neurites. Overexpressed in breast cancer cells, but not detected in the surrounding stroma and weakly, if at all, in normal breast epithelial cells (at protein level). Also expressed in several tumor cell lines.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000123091, Expressed in dorsolateral prefrontal cortex and 255 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9Y3C5, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000123091, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (when phosphorylated) with 14-3-3.

Interacts with the E3 ubiquitin-ligases NEDD4, ITCH, SMURF2 and WWP1 (By similarity).

Also interacts with the E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2N, but neither with CDC34, nor with UBE2L3.

Interacts with ZNF350, EPS15 and STAMBP. After TNF stimulation, interacts with TAX1BP1, TNFAIP3 and RIPK1; these interaction are transient and they are lost after 1 hour of stimulation with TNF (By similarity).

Interacts with GGA1.

By similarity8 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9Y3C5
With#Exp.IntAct
ADAMTSL4 - isoform 3 [Q6UY14-3]3EBI-396669,EBI-10173507
ANKRD13D - isoform 2 [Q6ZTN6-2]3EBI-396669,EBI-25840993
ANKRD44 - isoform 2 [Q8N8A2-2]3EBI-396669,EBI-21636328
ANUBL1 [Q86WR3]3EBI-396669,EBI-25880850
ANXA8 [P13928]3EBI-396669,EBI-2556915
APLN [D3DTF8]3EBI-396669,EBI-22002556
APP [P05067]3EBI-396669,EBI-77613
AQP8 [O94778]3EBI-396669,EBI-19124986
ARFGAP3 [Q9NP61]3EBI-396669,EBI-2875816
ARNT2 [Q86TN1]3EBI-396669,EBI-25844820
ASB13 [Q8WXK3]3EBI-396669,EBI-707573
ASB3 - isoform 3 [Q9Y575-3]3EBI-396669,EBI-14199987
ASCL4 [Q6XD76]3EBI-396669,EBI-10254793
ASIC4 - isoform 3 [Q96FT7-4]3EBI-396669,EBI-9089489
ATG10 [Q9H0Y0]3EBI-396669,EBI-1048913
ATP6V1B1 [P15313]3EBI-396669,EBI-2891281
ATP6V1B2 [P21281]3EBI-396669,EBI-4290814
BAG6 - isoform 2 [P46379-2]3EBI-396669,EBI-10988864
BAK1 [Q16611]3EBI-396669,EBI-519866
BAP18 [Q8IXM2]3EBI-396669,EBI-4280811
BECN1 [Q14457]3EBI-396669,EBI-949378
BRK1 [Q8WUW1]3EBI-396669,EBI-2837444
BRWD1 - isoform D [Q9NSI6-4]3EBI-396669,EBI-10693038
BSND [Q8WZ55]3EBI-396669,EBI-7996695
C12orf74 [Q32Q52]3EBI-396669,EBI-12891828
C7orf31 [Q8N865]3EBI-396669,EBI-10174456
C8orf48 [Q96LL4]3EBI-396669,EBI-751596
CAMKK1 - isoform 2 [Q8N5S9-2]3EBI-396669,EBI-25850646
CLIP3 [Q96DZ5]3EBI-396669,EBI-12823145
CNPY3 [Q9BT09]3EBI-396669,EBI-2835965
CNST - isoform 3 [Q6PJW8-3]3EBI-396669,EBI-25836090
COPS3 [Q9UNS2]3EBI-396669,EBI-350590
CSTA [P01040]3EBI-396669,EBI-724303
CXorf38 [Q8TB03]3EBI-396669,EBI-12024320
CYB5A [P00167]3EBI-396669,EBI-1047284
DCAF8 - isoform 2 [Q5TAQ9-2]3EBI-396669,EBI-25842815
DKFZp547K2416 [Q8NDP9]3EBI-396669,EBI-25842538
DMRTA1 [Q5VZB9]3EBI-396669,EBI-3939812
DOK3 - isoform 3 [Q7L591-3]3EBI-396669,EBI-10694655
DOM3Z [A0A024RCP2]3EBI-396669,EBI-25847826
DPYSL5 [Q9BPU6]3EBI-396669,EBI-724653
EED - isoform 2 [O75530-2]3EBI-396669,EBI-11132357
EPN3 [I6L9I8]3EBI-396669,EBI-12866582
ESM1 [Q9NQ30]3EBI-396669,EBI-12260294
ESRP1 [Q6NXG1]3EBI-396669,EBI-10213520
EYA3 [Q99504]3EBI-396669,EBI-9089567
FABP7 [O15540]3EBI-396669,EBI-10697159
FAHD1 - isoform 2 [Q6P587-2]3EBI-396669,EBI-12902289
FAM117B [Q6P1L5]3EBI-396669,EBI-3893327
FAM163A [Q96GL9]3EBI-396669,EBI-11793142
FAM98C [Q17RN3]3EBI-396669,EBI-5461838
FANCL [Q9NW38]3EBI-396669,EBI-2339898
FOSL1 [P15407]3EBI-396669,EBI-744510
G6PC [P35575]3EBI-396669,EBI-3906612
GATA1 - isoform 2 [P15976-2]3EBI-396669,EBI-9090198
GATA2 - isoform 2 [P23769-2]3EBI-396669,EBI-21856389
GFOD1 [Q9NXC2]3EBI-396669,EBI-8799578
GGA1 [Q9UJY5]3EBI-396669,EBI-447141
GNB2 [P62879]3EBI-396669,EBI-356942
GOLGA2P5 [Q9HBQ8]3EBI-396669,EBI-22000587
GPANK1 [O95872]3EBI-396669,EBI-751540
GPR141 [Q7Z602]3EBI-396669,EBI-21649723
GPSM3 [Q9Y4H4]3EBI-396669,EBI-347538
H3-5 [Q6NXT2]3EBI-396669,EBI-2868501
H3C12 [P68431]3EBI-396669,EBI-79722
hCG_41307 [A0A024R1L7]3EBI-396669,EBI-25849938
HK3 [P52790]3EBI-396669,EBI-2965780
HOXC4 [P09017]3EBI-396669,EBI-3923226
IL16 - isoform 2 [Q14005-2]3EBI-396669,EBI-17178971
ILF3 [Q9NXX0]3EBI-396669,EBI-743980
ING4 [Q9UNL4]3EBI-396669,EBI-2866661
IQCF2 [Q8IXL9]3EBI-396669,EBI-10238842
IQUB [Q8NA54]3EBI-396669,EBI-10220600
ITCH [Q96J02]2EBI-396669,EBI-1564678
KBTBD4 - isoform 2 [Q9NVX7-2]3EBI-396669,EBI-25871195
KCTD13 [Q8WZ19]3EBI-396669,EBI-742916
KLF15 [Q9UIH9]3EBI-396669,EBI-2796400
KLHL20 [Q9Y2M5]3EBI-396669,EBI-714379
KRT33B [Q14525]3EBI-396669,EBI-1049638
KRTAP19-7 [Q3SYF9]3EBI-396669,EBI-10241353
KRTAP8-1 [Q8IUC2]3EBI-396669,EBI-10261141
LASP1 - isoform 2 [Q14847-2]3EBI-396669,EBI-9088686
LCE1B [Q5T7P3]3EBI-396669,EBI-10245913
LHX6 [Q9UPM6]3EBI-396669,EBI-10258746
LHX8 [Q68G74]3EBI-396669,EBI-8474075
LNX1 [Q8TBB1]3EBI-396669,EBI-739832
LOC401296 [A2RU56]3EBI-396669,EBI-9088215
LOXL4 [Q96JB6]3EBI-396669,EBI-749562
LPIN1 [Q14693]3EBI-396669,EBI-5278370
MAX - isoform 4 [P61244-4]3EBI-396669,EBI-25848049
MECOM - isoform 9 [Q03112-9]3EBI-396669,EBI-23820194
METTL27 [Q8N6F8]3EBI-396669,EBI-8487781
MLC1 [Q15049]3EBI-396669,EBI-8475277
MNAT1 [P51948]3EBI-396669,EBI-716139
MPND [Q8N594]3EBI-396669,EBI-2512452
MSRB3 - isoform 2 [Q8IXL7-2]3EBI-396669,EBI-10699187
NEDD4 [P46934]2EBI-396669,EBI-726944
NGEF [Q8N5V2]3EBI-396669,EBI-718372
NHLRC2 - isoform 2 [Q8NBF2-2]3EBI-396669,EBI-10697320
NR1D2 [Q14995]3EBI-396669,EBI-6144053
NSMF - isoform 6 [Q6X4W1-6]3EBI-396669,EBI-25842707
NUDT1 - isoform p18 [P36639-4]3EBI-396669,EBI-25834643
NVL - isoform 5 [O15381-5]3EBI-396669,EBI-18577082
ODF2 - isoform 2 [Q5BJF6-2]3EBI-396669,EBI-9090919
OTUB1 [Q96FW1]3EBI-396669,EBI-1058491
OTUD7B - isoform 2 [Q6GQQ9-2]3EBI-396669,EBI-25830200
PARP11 - isoform 4 [Q9NR21-5]3EBI-396669,EBI-17159452
PCMTD2 [Q9NV79]3EBI-396669,EBI-6309018
PLEKHB1 - isoform 2 [Q9UF11-2]3EBI-396669,EBI-12832742
POC5 - isoform 3 [Q8NA72-3]3EBI-396669,EBI-11751537
PRKAA2 [P54646]3EBI-396669,EBI-1383852
PRKAB2 [O43741]3EBI-396669,EBI-1053424
PRKN - isoform 5 [O60260-5]3EBI-396669,EBI-21251460
PRPS2 [P11908]3EBI-396669,EBI-4290895
PSMB10 [P40306]3EBI-396669,EBI-603329
PSMB4 [P28070]3EBI-396669,EBI-603350
PSMB8 - isoform 2 [P28062-2]3EBI-396669,EBI-372312
QARS1 [P47897]10EBI-396669,EBI-347462
RABGEF1 - isoform 3 [Q9UJ41-4]3EBI-396669,EBI-14093916
RAI2 [Q9Y5P3]3EBI-396669,EBI-746228
RBM14 [Q96PK6]3EBI-396669,EBI-954272
RHBDD2 - isoform 3 [Q6NTF9-3]3EBI-396669,EBI-17589229
RNF10 [Q8N5U6]3EBI-396669,EBI-714023
RNF112 [Q9ULX5]3EBI-396669,EBI-25829984
RNF138 [Q8WVD3]3EBI-396669,EBI-749039
RNF14 [Q9UBS8]3EBI-396669,EBI-2130308
RNF168 [Q8IYW5]4EBI-396669,EBI-914207
RNF183 [Q96D59]3EBI-396669,EBI-743938
RNF208 [Q9H0X6]3EBI-396669,EBI-751555
RPS15A [P62244]3EBI-396669,EBI-347895
RPS27A [P62979]4EBI-396669,EBI-357375
RUSC1-AS1 [Q66K80]3EBI-396669,EBI-10248967
RYBP [Q8N488]3EBI-396669,EBI-752324
SAMD7 [Q7Z3H4]3EBI-396669,EBI-12148649
SDC2 [P34741]3EBI-396669,EBI-1172957
SDCBP [O00560]3EBI-396669,EBI-727004
SEMA4G - isoform 3 [Q9NTN9-3]3EBI-396669,EBI-9089805
SH3KBP1 [Q96B97]3EBI-396669,EBI-346595
SHFL - isoform 3 [Q9NUL5-3]3EBI-396669,EBI-22000547
SHOX2 - isoform 3 [O60902-3]3EBI-396669,EBI-9092164
SLC6A13 - isoform 3 [Q9NSD5-3]3EBI-396669,EBI-25831241
SMURF1 - isoform Short [Q9HCE7-2]3EBI-396669,EBI-9845742
SMURF2 [Q9HAU4]5EBI-396669,EBI-396727
SNAPC3 [Q92966]3EBI-396669,EBI-1760638
SNW1 [Q13573]3EBI-396669,EBI-632715
SPAG8 - isoform 2 [Q99932-2]3EBI-396669,EBI-11959123
SPATA3 [A0A024R4B0]3EBI-396669,EBI-14123856
SPATA8 [Q6RVD6]3EBI-396669,EBI-8635958
SPPL2B - isoform 2 [Q8TCT7-2]3EBI-396669,EBI-8345366
SPRED2 [Q7Z698]3EBI-396669,EBI-7082156
SPRY4 [Q9C004]3EBI-396669,EBI-354861
SPSB1 [Q96BD6]3EBI-396669,EBI-2659201
SPSB2 [Q99619]3EBI-396669,EBI-2323209
STAM - isoform 2 [Q92783-2]3EBI-396669,EBI-12025738
STAM2 [O75886]4EBI-396669,EBI-373258
STAMBP [O95630]5EBI-396669,EBI-396676
SYT16 - isoform 3 [Q17RD7-3]3EBI-396669,EBI-25861603
SYT3 [Q9BQG1]3EBI-396669,EBI-17284568
TASOR2 [Q5VWN6]3EBI-396669,EBI-745958
TAX1BP1 [Q86VP1]2EBI-396669,EBI-529518
TBPL1 [P62380]3EBI-396669,EBI-716225
TCEAL8 [Q8IYN2]3EBI-396669,EBI-2116184
TDG [Q13569]3EBI-396669,EBI-348333
TEAD1 - isoform 2 [P28347-2]3EBI-396669,EBI-12151837
TENT5B [Q96A09]3EBI-396669,EBI-752030
TEX19 [Q8NA77]3EBI-396669,EBI-13323487
TIMM17B [O60830]3EBI-396669,EBI-2372529
TLE1 [Q04724]3EBI-396669,EBI-711424
TMEM61 [Q8N0U2]3EBI-396669,EBI-25830583
tmp_locus_54 [Q53NU3]3EBI-396669,EBI-10242677
TMUB2 - isoform 4 [Q71RG4-4]3EBI-396669,EBI-25831574
TNFAIP3 [P21580]2EBI-396669,EBI-527670
TOLLIP [Q9H0E2]3EBI-396669,EBI-74615
TRIM21 [P19474]3EBI-396669,EBI-81290
TRIM35 - isoform 2 [Q9UPQ4-2]3EBI-396669,EBI-17716262
TRIM39 - isoform 2 [Q9HCM9-2]3EBI-396669,EBI-11523450
TSC1 [Q86WV8]3EBI-396669,EBI-12806590
TSC22D4 [Q9Y3Q8]3EBI-396669,EBI-739485
TUBGCP4 - isoform 2 [Q9UGJ1-2]3EBI-396669,EBI-10964469
UBA52 [P62987]4EBI-396669,EBI-357304
UBAC1 [Q9BSL1]3EBI-396669,EBI-749370
UBAC2 - isoform 4 [Q8NBM4-4]3EBI-396669,EBI-25840976
UBASH3A - isoform 2 [P57075-2]3EBI-396669,EBI-7353612
UBB [P0CG47]3EBI-396669,EBI-413034
UBE2D1 [P51668]9EBI-396669,EBI-743540
UBE2D2 [P62837]10EBI-396669,EBI-347677
UBE2D3 [P61077]3EBI-396669,EBI-348268
UBE2D4 [Q9Y2X8]10EBI-396669,EBI-745527
UBE2E1 [P51965]2EBI-396669,EBI-348546
UBE2E3 [Q969T4]4EBI-396669,EBI-348496
UBE2N [P61088]4EBI-396669,EBI-1052908
UBE2V1 [Q13404]4EBI-396669,EBI-1050671
UBQLN2 [Q9UHD9]4EBI-396669,EBI-947187
UBXN1 - isoform 2 [Q04323-2]3EBI-396669,EBI-11530712
UIMC1 - isoform 2 [Q96RL1-2]3EBI-396669,EBI-17761788
USP2 - isoform 3 [O75604-3]3EBI-396669,EBI-10696113
VDAC2 [P45880]3EBI-396669,EBI-354022
VHL - isoform 2 [P40337-2]3EBI-396669,EBI-12157263
VPS37A [Q8NEZ2]3EBI-396669,EBI-2850578
VSX2 [P58304]3EBI-396669,EBI-6427899
WDR61 [Q9GZS3]3EBI-396669,EBI-358545
WDR77 [Q9BQA1]3EBI-396669,EBI-1237307
WDR83 [Q9BRX9]3EBI-396669,EBI-7705033
WWOX - isoform 5 [Q9NZC7-5]3EBI-396669,EBI-12040603
WWP2 [O00308]7EBI-396669,EBI-743923
XRCC6 [P12956]3EBI-396669,EBI-353208
ZBTB24 - isoform 2 [O43167-2]3EBI-396669,EBI-25842419
ZC2HC1C - isoform 2 [Q53FD0-2]3EBI-396669,EBI-14104088
ZDHHC20 - isoform 4 [Q5W0Z9-4]3EBI-396669,EBI-25840130
ZKSCAN8 [Q15776]3EBI-396669,EBI-2602314
ZNF180 - isoform 4 [Q9UJW8-4]3EBI-396669,EBI-12055755
ZNF296 [Q8WUU4]3EBI-396669,EBI-8834821
ZNF302 - isoform 2 [Q9NR11-2]3EBI-396669,EBI-12988373
ZNF366 [Q8N895]3EBI-396669,EBI-2813661
ZNF444 - isoform 2 [Q8N0Y2-2]3EBI-396669,EBI-12010736
ZNF488 - isoform 2 [Q96MN9-2]3EBI-396669,EBI-25831733
ZNF497 [Q6ZNH5]3EBI-396669,EBI-10486136
ZNF524 [Q96C55]3EBI-396669,EBI-10283126
ZNF57 [Q68EA5]3EBI-396669,EBI-8490788
ZNF641 - isoform 2 [Q96N77-2]3EBI-396669,EBI-12939666
ZNF670 [Q9BS34]3EBI-396669,EBI-745276
ZXDC [Q2QGD7]3EBI-396669,EBI-1538838
A0A384ME253EBI-396669,EBI-10211777
B7Z3E83EBI-396669,EBI-25831617
Q7L8T73EBI-396669,EBI-25831943

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
117941, 157 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9Y3C5

Protein interaction database and analysis system

More...
IntActi
Q9Y3C5, 271 interactors

Molecular INTeraction database

More...
MINTi
Q9Y3C5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000242719

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y3C5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y3C5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi37 – 40PPxY motif4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PPxY motif mediates interaction with NEDD4.By similarity

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 140RING-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0800, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000110988

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_123539_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y3C5

Identification of Orthologs from Complete Genome Data

More...
OMAi
QEQIHVP

Database of Orthologous Groups

More...
OrthoDBi
1261762at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y3C5

TreeFam database of animal gene trees

More...
TreeFami
TF318022

Family and domain databases

Conserved Domains Database

More...
CDDi
cd16468, RING-H2_RNF11, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042981, RNF11_RING-H2
IPR001841, Znf_RING
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13639, zf-RING_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00184, RING, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50089, ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y3C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNCLKSPTS DDISLLHESQ SDRASFGEGT EPDQEPPPPY QEQVPVPVYH
60 70 80 90 100
PTPSQTRLAT QLTEEEQIRI AQRIGLIQHL PKGVYDPGRD GSEKKIRECV
110 120 130 140 150
ICMMDFVYGD PIRFLPCMHI YHLDCIDDWL MRSFTCPSCM EPVDAALLSS

YETN
Length:154
Mass (Da):17,444
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC368E38148FC1D0D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti124D → G in BAF85736 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05827211D → E. Corresponds to variant dbSNP:rs12077069Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB024703 mRNA Translation: BAA84683.1
AF151881 mRNA Translation: AAD34118.1
AK293047 mRNA Translation: BAF85736.1
AK313140 mRNA Translation: BAG35959.1
AL162430 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX06831.1
BC020964 mRNA Translation: AAH20964.1
BC047654 mRNA Translation: AAH47654.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS556.1

NCBI Reference Sequences

More...
RefSeqi
NP_055187.1, NM_014372.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000242719; ENSP00000242719; ENSG00000123091

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26994

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26994

UCSC genome browser

More...
UCSCi
uc001csi.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB024703 mRNA Translation: BAA84683.1
AF151881 mRNA Translation: AAD34118.1
AK293047 mRNA Translation: BAF85736.1
AK313140 mRNA Translation: BAG35959.1
AL162430 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX06831.1
BC020964 mRNA Translation: AAH20964.1
BC047654 mRNA Translation: AAH47654.1
CCDSiCCDS556.1
RefSeqiNP_055187.1, NM_014372.4

3D structure databases

SMRiQ9Y3C5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117941, 157 interactors
CORUMiQ9Y3C5
IntActiQ9Y3C5, 271 interactors
MINTiQ9Y3C5
STRINGi9606.ENSP00000242719

PTM databases

iPTMnetiQ9Y3C5
PhosphoSitePlusiQ9Y3C5
SwissPalmiQ9Y3C5

Genetic variation databases

BioMutaiRNF11
DMDMi21362884

Proteomic databases

EPDiQ9Y3C5
jPOSTiQ9Y3C5
MassIVEiQ9Y3C5
MaxQBiQ9Y3C5
PaxDbiQ9Y3C5
PeptideAtlasiQ9Y3C5
PRIDEiQ9Y3C5
ProteomicsDBi86014

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32937, 170 antibodies

The DNASU plasmid repository

More...
DNASUi
26994

Genome annotation databases

EnsembliENST00000242719; ENSP00000242719; ENSG00000123091
GeneIDi26994
KEGGihsa:26994
UCSCiuc001csi.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26994
DisGeNETi26994

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RNF11
HGNCiHGNC:10056, RNF11
HPAiENSG00000123091, Low tissue specificity
MIMi612598, gene
neXtProtiNX_Q9Y3C5
OpenTargetsiENSG00000123091
PharmGKBiPA34420
VEuPathDBiHostDB:ENSG00000123091.4

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0800, Eukaryota
GeneTreeiENSGT00730000110988
HOGENOMiCLU_123539_1_0_1
InParanoidiQ9Y3C5
OMAiQEQIHVP
OrthoDBi1261762at2759
PhylomeDBiQ9Y3C5
TreeFamiTF318022

Enzyme and pathway databases

PathwayCommonsiQ9Y3C5
SIGNORiQ9Y3C5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
26994, 32 hits in 996 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RNF11, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RNF11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
26994
PharosiQ9Y3C5, Tbio

Protein Ontology

More...
PROi
PR:Q9Y3C5
RNActiQ9Y3C5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000123091, Expressed in dorsolateral prefrontal cortex and 255 other tissues
GenevisibleiQ9Y3C5, HS

Family and domain databases

CDDicd16468, RING-H2_RNF11, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR042981, RNF11_RING-H2
IPR001841, Znf_RING
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF13639, zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184, RING, 1 hit
PROSITEiView protein in PROSITE
PS50089, ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRNF11_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y3C5
Secondary accession number(s): A8KAI2, Q5T7R8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: November 1, 1999
Last modified: April 7, 2021
This is version 166 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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