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Entry version 150 (10 Apr 2019)
Sequence version 2 (19 Sep 2006)
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Protein

Nucleolar protein 16

Gene

NOP16

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • ribosomal large subunit biogenesis Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar protein 16
Alternative name(s):
HBV pre-S2 trans-regulated protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOP16
ORF Names:CGI-117, HSPC111
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000048162.19

Human Gene Nomenclature Database

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HGNCi
HGNC:26934 NOP16

Online Mendelian Inheritance in Man (OMIM)

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MIMi
612861 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y3C1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51491

Open Targets

More...
OpenTargetsi
ENSG00000048162

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164724025

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NOP16

Domain mapping of disease mutations (DMDM)

More...
DMDMi
115311631

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000508171 – 178Nucleolar protein 16Add BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei8PhosphothreonineCombined sources1
Modified residuei16PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki74Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei90N6-acetyllysineCombined sources1
Modified residuei144PhosphothreonineCombined sources1
Isoform 2 (identifier: Q9Y3C1-2)
Cross-linki166Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sourcesCurated
Cross-linki172Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sourcesCurated
Isoform 3 (identifier: Q9Y3C1-3)
Cross-linki167Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki173Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y3C1

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9Y3C1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y3C1

PeptideAtlas

More...
PeptideAtlasi
Q9Y3C1

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y3C1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
86010

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q9Y3C1-1 [Q9Y3C1-1]

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

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SWISS-2DPAGEi
Q9Y3C1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y3C1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y3C1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9Y3C1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000048162 Expressed in 224 organ(s), highest expression level in layer of synovial tissue

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9Y3C1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y3C1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA036506
HPA058147

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119568, 46 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y3C1, 18 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000480832

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Y3C1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NOP16 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG4706 Eukaryota
ENOG4111QB6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163830

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000169215

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG098588

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9Y3C1

Identification of Orthologs from Complete Genome Data

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OMAi
TYLMDKY

Database of Orthologous Groups

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OrthoDBi
1431164at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y3C1

TreeFam database of animal gene trees

More...
TreeFami
TF323541

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR019002 Ribosome_biogenesis_Nop16

The PANTHER Classification System

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PANTHERi
PTHR13243 PTHR13243, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09420 Nop16, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y3C1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPKAKGKTRR QKFGYSVNRK RLNRNARRKA APRIECSHIR HAWDHAKSVR
60 70 80 90 100
QNLAEMGLAV DPNRAVPLRK RKVKAMEVDI EERPKELVRK PYVLNDLEAE
110 120 130 140 150
ASLPEKKGNT LSRDLIDYVR YMVENHGEDY KAMARDEKNY YQDTPKQIRS
160 170
KINVYKRFYP AEWQDFLDSL QKRKMEVE
Length:178
Mass (Da):21,188
Last modified:September 19, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD9139BE32DA81FC5
GO
Isoform 2 (identifier: Q9Y3C1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     132-178: AMARDEKNYY...SLQKRKMEVE → SGKTSSILCR...RVGDVNIVCT

Show »
Length:236
Mass (Da):27,306
Checksum:iFD6FA2B669720AA7
GO
Isoform 3 (identifier: Q9Y3C1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     132-178: AMARDEKNYY...SLQKRKMEVE → QSGKTSSILC...QNLLFSGWVM

Note: No experimental confirmation available.Combined sources
Show »
Length:232
Mass (Da):26,561
Checksum:i6DB17D8B0E4F0AD7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DGU5A0A0C4DGU5_HUMAN
Nucleolar protein 16
NOP16
231Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RIC3D6RIC3_HUMAN
Nucleolar protein 16
NOP16
150Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X2G6A0A087X2G6_HUMAN
Nucleolar protein 16
NOP16
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC60D6RC60_HUMAN
Nucleolar protein 16
NOP16
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WU10A0A087WU10_HUMAN
Nucleolar protein 16
NOP16
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH19331 differs from that shown. Reason: Frameshift at position 195.Curated
The sequence BAG62525 differs from that shown. Reason: Frameshift at position 195.Curated
The sequence EAW85085 differs from that shown. Reason: Frameshift at position 195.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti32 – 33PR → RG in AAD34112 (PubMed:10810093).Curated2
Sequence conflicti32 – 33PR → RG in AAF29075 (PubMed:11042152).Curated2
Sequence conflicti178E → D in CAG33450 (Ref. 5) Curated1
Isoform 2 (identifier: Q9Y3C1-2)
Sequence conflicti171C → F in BAG62525 (PubMed:14702039).Combined sourcesCurated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_045583132 – 178AMARD…KMEVE → SGKTSSILCRRGRWRWSDWF TSQLPQAEASPGPVKLEPGC KARRCCVAPEELARSHGIRR LHTRAHSPLWGRNCSQRLQF IFIWGFTEKPEPAVFRVGDV NIVCT in isoform 2. 2 PublicationsAdd BLAST47
Alternative sequenceiVSP_057393132 – 178AMARD…KMEVE → QSGKTSSILCRRGRWRWSDW FTSQLPQAEASPGPVKLEPG CKARRCCVAPEELARSHGIR RLHTHVHTPRSGEGTVLRGS NLYSSGGSRKSQNLLFSGWV M in isoform 3. 1 PublicationAdd BLAST47

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY561704 mRNA Translation: AAS66977.1
AF151875 mRNA Translation: AAD34112.1
AF161460 mRNA Translation: AAF29075.1
AK300883 mRNA Translation: BAG62525.1 Frameshift.
CR457169 mRNA Translation: CAG33450.1
AC138956 Genomic DNA No translation available.
KF459629 Genomic DNA No translation available.
CH471195 Genomic DNA Translation: EAW85084.1
CH471195 Genomic DNA Translation: EAW85085.1 Frameshift.
BC019331 mRNA Translation: AAH19331.1 Frameshift.
BC032424 mRNA Translation: AAH32424.1
BC040106 mRNA Translation: AAH40106.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43403.1 [Q9Y3C1-1]
CCDS78091.1 [Q9Y3C1-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001243468.2, NM_001256539.3 [Q9Y3C1-3]
NP_001243469.2, NM_001256540.3
NP_001278234.1, NM_001291305.2
NP_001278236.1, NM_001291307.2
NP_001278237.1, NM_001291308.2
NP_001304904.1, NM_001317975.1
NP_057475.2, NM_016391.7 [Q9Y3C1-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.696283

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000614830; ENSP00000480832; ENSG00000048162 [Q9Y3C1-1]
ENST00000618911; ENSP00000483001; ENSG00000048162 [Q9Y3C1-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
51491

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51491

UCSC genome browser

More...
UCSCi
uc032vuv.2 human [Q9Y3C1-1]
uc063jyi.1 human

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY561704 mRNA Translation: AAS66977.1
AF151875 mRNA Translation: AAD34112.1
AF161460 mRNA Translation: AAF29075.1
AK300883 mRNA Translation: BAG62525.1 Frameshift.
CR457169 mRNA Translation: CAG33450.1
AC138956 Genomic DNA No translation available.
KF459629 Genomic DNA No translation available.
CH471195 Genomic DNA Translation: EAW85084.1
CH471195 Genomic DNA Translation: EAW85085.1 Frameshift.
BC019331 mRNA Translation: AAH19331.1 Frameshift.
BC032424 mRNA Translation: AAH32424.1
BC040106 mRNA Translation: AAH40106.1
CCDSiCCDS43403.1 [Q9Y3C1-1]
CCDS78091.1 [Q9Y3C1-3]
RefSeqiNP_001243468.2, NM_001256539.3 [Q9Y3C1-3]
NP_001243469.2, NM_001256540.3
NP_001278234.1, NM_001291305.2
NP_001278236.1, NM_001291307.2
NP_001278237.1, NM_001291308.2
NP_001304904.1, NM_001317975.1
NP_057475.2, NM_016391.7 [Q9Y3C1-1]
UniGeneiHs.696283

3D structure databases

ProteinModelPortaliQ9Y3C1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119568, 46 interactors
IntActiQ9Y3C1, 18 interactors
STRINGi9606.ENSP00000480832

PTM databases

iPTMnetiQ9Y3C1
PhosphoSitePlusiQ9Y3C1
SwissPalmiQ9Y3C1

Polymorphism and mutation databases

BioMutaiNOP16
DMDMi115311631

2D gel databases

SWISS-2DPAGEiQ9Y3C1

Proteomic databases

EPDiQ9Y3C1
jPOSTiQ9Y3C1
PaxDbiQ9Y3C1
PeptideAtlasiQ9Y3C1
PRIDEiQ9Y3C1
ProteomicsDBi86010
TopDownProteomicsiQ9Y3C1-1 [Q9Y3C1-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51491
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000614830; ENSP00000480832; ENSG00000048162 [Q9Y3C1-1]
ENST00000618911; ENSP00000483001; ENSG00000048162 [Q9Y3C1-3]
GeneIDi51491
KEGGihsa:51491
UCSCiuc032vuv.2 human [Q9Y3C1-1]
uc063jyi.1 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
51491
DisGeNETi51491
EuPathDBiHostDB:ENSG00000048162.19

GeneCards: human genes, protein and diseases

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GeneCardsi
NOP16
HGNCiHGNC:26934 NOP16
HPAiHPA036506
HPA058147
MIMi612861 gene
neXtProtiNX_Q9Y3C1
OpenTargetsiENSG00000048162
PharmGKBiPA164724025

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG4706 Eukaryota
ENOG4111QB6 LUCA
GeneTreeiENSGT00940000163830
HOGENOMiHOG000169215
HOVERGENiHBG098588
InParanoidiQ9Y3C1
OMAiTYLMDKY
OrthoDBi1431164at2759
PhylomeDBiQ9Y3C1
TreeFamiTF323541

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NOP16 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51491

Protein Ontology

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PROi
PR:Q9Y3C1

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000048162 Expressed in 224 organ(s), highest expression level in layer of synovial tissue
ExpressionAtlasiQ9Y3C1 baseline and differential
GenevisibleiQ9Y3C1 HS

Family and domain databases

InterProiView protein in InterPro
IPR019002 Ribosome_biogenesis_Nop16
PANTHERiPTHR13243 PTHR13243, 1 hit
PfamiView protein in Pfam
PF09420 Nop16, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOP16_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y3C1
Secondary accession number(s): B4DV13
, D6RGD3, Q05D05, Q6IAI6, Q6PIM0, Q8IXL5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: September 19, 2006
Last modified: April 10, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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