UniProtKB - Q9Y383 (LC7L2_HUMAN)

BLAST

>sp|Q9Y383|LC7L2_HUMAN Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2
MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL
KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA
AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS
SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN
QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR
HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR
DRDRKDKKRSYESANGRSEDRRSSEEREAGEI

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History
Entry version 156 (12 Sep 2018)
Sequence version 2 (10 May 2004)
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Protein

Putative RNA-binding protein Luc7-like 2

Gene

LUC7L2

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May bind to RNA via its Arg/Ser-rich domain.

GO - Molecular functionⁱ

enzyme binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 19574390
mRNA binding Source: GO_Central
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22681889

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mRNA splice site selection Source: GO_Central

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Putative RNA-binding protein Luc7-like 2
Gene namesⁱ	Name:LUC7L2 ORF Names:CGI-59, CGI-74
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000146963.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21608 LUC7L2
MIMⁱ	613056 gene
neXtProtⁱ	NX_Q9Y383

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	266	K → R: Induces a decrease in lysyl-hydroxylation. Abolishes lysyl-hydroxylation; when associated with R-269. 1 Publication		1
Mutagenesisⁱ	269	K → R: Induces a decrease in lysyl-hydroxylation. Abolishes lysyl-hydroxylation; when associated with R-266. 1 Publication		1

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000146963
PharmGKBⁱ	PA134873425

Polymorphism and mutation databases

BioMutaⁱ	LUC7L2
DMDMⁱ	47116960

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000187282	1 – 392	Putative RNA-binding protein Luc7-like 2Add BLAST		392

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	18	PhosphoserineCombined sources	1
Modified residueⁱ	266	5-hydroxylysine; by JMJD61 Publication	1
Modified residueⁱ	269	5-hydroxylysine; by JMJD61 Publication	1

Keywords - PTMⁱ

Hydroxylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q9Y383
PaxDbⁱ	Q9Y383
PeptideAtlas More...PeptideAtlasⁱ	Q9Y383
PRIDEⁱ	Q9Y383
ProteomicsDBⁱ	85982 85983 [Q9Y383-2]

PTM databases

iPTMnetⁱ	Q9Y383
PhosphoSitePlusⁱ	Q9Y383
SwissPalmⁱ	Q9Y383

Miscellaneous databases

PMAP-CutDBⁱ	Q9Y383

PMAP-CutDBⁱ

Q9Y383

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000146963 Expressed in 221 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_LUC7L2
ExpressionAtlasⁱ	Q9Y383 baseline and differential
Genevisibleⁱ	Q9Y383 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA051631

HPAⁱ

HPA051631

Interactionⁱ

Subunit structureⁱ

Interacts with SCNM1.By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
APPBP2	Q92624	5	EBI-352851,EBI-743771
MAP1LC3B	Q9GZQ8	3	EBI-352851,EBI-373144
NFYA	P23511	3	EBI-352851,EBI-389739
SRPK1	Q96SB4	2	EBI-352851,EBI-539478
SRPK2	P78362	2	EBI-352851,EBI-593303
SRSF6	Q13247	5	EBI-352851,EBI-745230
SRSF7	Q16629	5	EBI-352851,EBI-398885

GO - Molecular functionⁱ

enzyme binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 19574390

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	119646, 178 interactors
CORUMⁱ	Q9Y383
Database of interacting proteins More...DIPⁱ	DIP-32513N
IntActⁱ	Q9Y383, 67 interactors
Molecular INTeraction database More...MINTⁱ	Q9Y383
STRINGⁱ	9606.ENSP00000347005

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9Y383
SMRⁱ	Q9Y383
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	102 – 177	Sequence analysisAdd BLAST		76

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	239 – 388	Arg/Ser-richAdd BLAST		150

Sequence similaritiesⁱ

Belongs to the Luc7 family.Curated

Keywords - Domainⁱ

Coiled coil

Phylogenomic databases

eggNOGⁱ	KOG0796 Eukaryota COG5200 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000110670
HOVERGENⁱ	HBG062167
InParanoidⁱ	Q9Y383
KEGG Orthology (KO) More...KOⁱ	K13212
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0PSO
PhylomeDBⁱ	Q9Y383
TreeFamⁱ	TF317607

Family and domain databases

InterProⁱ	View protein in InterPro IPR004882 Luc7-rel
PANTHERⁱ	PTHR12375 PTHR12375, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03194 LUC7, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9Y383-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSAQAQMRAM LDQLMGTSRD GDTTRQRIKF SDDRVCKSHL LNCCPHDVLS 
        60         70         80         90        100
GTRMDLGECL KVHDLALRAD YEIASKEQDF FFELDAMDHL QSFIADCDRR 
       110        120        130        140        150
TEVAKKRLAE TQEEISAEVA AKAERVHELN EEIGKLLAKV EQLGAEGNVE 
       160        170        180        190        200
ESQKVMDEVE KARAKKREAE EVYRNSMPAS SFQQQKLRVC EVCSAYLGLH 
       210        220        230        240        250
DNDRRLADHF GGKLHLGFIE IREKLEELKR VVAEKQEKRN QERLKRREER 
       260        270        280        290        300
EREEREKLRR SRSHSKNPKR SRSREHRRHR SRSMSRERKR RTRSKSREKR 
       310        320        330        340        350
HRHRSRSSSR SRSRSHQRSR HSSRDRSRER SKRRSSKERF RDQDLASCDR 
       360        370        380        390 
DRSSRDRSPR DRDRKDKKRS YESANGRSED RRSSEEREAG EI

Length:392

Mass (Da):46,514

Last modified:May 10, 2004 - v2

Checksum:ⁱ1C559CCE0F23F693

Isoform 2 (identifier: Q9Y383-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-21: MSAQAQMRAMLDQLMGTSRDG → MPAYLNLQGSVRKAPHSPSR

« Hide

        10         20         30         40         50
MPAYLNLQGS VRKAPHSPSR DTTRQRIKFS DDRVCKSHLL NCCPHDVLSG 
        60         70         80         90        100
TRMDLGECLK VHDLALRADY EIASKEQDFF FELDAMDHLQ SFIADCDRRT 
       110        120        130        140        150
EVAKKRLAET QEEISAEVAA KAERVHELNE EIGKLLAKVE QLGAEGNVEE 
       160        170        180        190        200
SQKVMDEVEK ARAKKREAEE VYRNSMPASS FQQQKLRVCE VCSAYLGLHD 
       210        220        230        240        250
NDRRLADHFG GKLHLGFIEI REKLEELKRV VAEKQEKRNQ ERLKRREERE 
       260        270        280        290        300
REEREKLRRS RSHSKNPKRS RSREHRRHRS RSMSRERKRR TRSKSREKRH 
       310        320        330        340        350
RHRSRSSSRS RSRSHQRSRH SSRDRSRERS KRRSSKERFR DQDLASCDRD 
       360        370        380        390 
RSSRDRSPRD RDRKDKKRSY ESANGRSEDR RSSEEREAGE I

Note: No experimental confirmation available.

Show »

Length:391

Mass (Da):46,425

Checksum:ⁱ68FBCFE447A3E0E5

Isoform 3 (identifier: Q9Y383-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-20: MSAQAQMRAMLDQLMGTSRD → MVIHSQLKKIQGASERM

« Hide

        10         20         30         40         50
MVIHSQLKKI QGASERMGDT TRQRIKFSDD RVCKSHLLNC CPHDVLSGTR 
        60         70         80         90        100
MDLGECLKVH DLALRADYEI ASKEQDFFFE LDAMDHLQSF IADCDRRTEV 
       110        120        130        140        150
AKKRLAETQE EISAEVAAKA ERVHELNEEI GKLLAKVEQL GAEGNVEESQ 
       160        170        180        190        200
KVMDEVEKAR AKKREAEEVY RNSMPASSFQ QQKLRVCEVC SAYLGLHDND 
       210        220        230        240        250
RRLADHFGGK LHLGFIEIRE KLEELKRVVA EKQEKRNQER LKRREERERE 
       260        270        280        290        300
EREKLRRSRS HSKNPKRSRS REHRRHRSRS MSRERKRRTR SKSREKRHRH 
       310        320        330        340        350
RSRSSSRSRS RSHQRSRHSS RDRSRERSKR RSSKERFRDQ DLASCDRDRS 
       360        370        380 
SRDRSPRDRD RKDKKRSYES ANGRSEDRRS SEEREAGEI

Note: No experimental confirmation available.

Show »

Length:389

Mass (Da):46,229

Checksum:ⁱA58A74530C83E98E

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A0A0A6YYJ8	A0A0A6YYJ8_HUMAN	Putative RNA-binding protein Luc7-l... Putative RNA-binding protein Luc7-like 2	LUC7L2	458	Annotation score:
V9GZ75	V9GZ75_HUMAN	Putative RNA-binding protein Luc7-l... Putative RNA-binding protein Luc7-like 2	LUC7L2	54	Annotation score:
F8WEU3	F8WEU3_HUMAN	Putative RNA-binding protein Luc7-l... Putative RNA-binding protein Luc7-like 2	LUC7L2	83	Annotation score:

Sequence cautionⁱ

The sequence AAD34069 differs from that shown. Reason: Frameshift at position 388.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	27	R → Q in BAA91737 (PubMed:14702039).Curated		1
Sequence conflictⁱ	389 – 390	AG → QR in AAD34054 (PubMed:10810093).Curated		2

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_034067	361	D → E. Corresponds to variant dbSNP:rs3757435Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_010217	1 – 21	MSAQA…TSRDG → MPAYLNLQGSVRKAPHSPSR in isoform 2. 1 PublicationAdd BLAST		21
Alternative sequenceⁱVSP_044896	1 – 20	MSAQA…GTSRD → MVIHSQLKKIQGASERM in isoform 3. 1 PublicationAdd BLAST		20

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF151817 mRNA Translation: AAD34054.1 AF151832 mRNA Translation: AAD34069.1 Frameshift. AK001476 mRNA Translation: BAA91713.1 AK001519 mRNA Translation: BAA91737.1 AK022895 mRNA Translation: BAB14297.1 AK298166 mRNA Translation: BAH12736.1 BC017163 mRNA Translation: AAH17163.1 BC042625 mRNA Translation: AAH42625.1 BC050708 mRNA Translation: AAH50708.1 BC056886 mRNA Translation: AAH56886.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS43656.1 [Q9Y383-1] CCDS59085.1 [Q9Y383-3] CCDS59510.1 [Q9Y383-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001231514.1, NM_001244585.1 [Q9Y383-3] NP_001257572.1, NM_001270643.1 [Q9Y383-2] NP_057103.2, NM_016019.4 [Q9Y383-1]
UniGeneⁱ	Hs.731488

Genome annotation databases

Ensemblⁱ	ENST00000263545; ENSP00000263545; ENSG00000146963 [Q9Y383-3] ENST00000354926; ENSP00000347005; ENSG00000146963 [Q9Y383-1] ENST00000541170; ENSP00000441604; ENSG00000146963 [Q9Y383-3] ENST00000619796; ENSP00000483438; ENSG00000146963 [Q9Y383-2]
GeneIDⁱ	51631
KEGGⁱ	hsa:51631
UCSC genome browser More...UCSCⁱ	uc003vux.5 human [Q9Y383-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9Y383	Putative RNA-binding protein Luc7-like 2 isoform 1		CALJA		392	UniRef100_Q9Y383
C7orf55-LUC7L2 readthrough		PANTR		392
LUC7 like 2, pre-mRNA splicing factor		SAIBB		392
Putative RNA-binding protein Luc7-like 2		MACMU		392
Uncharacterized protein		Cebus capucinus imitator		392
+7
Q9Y383-2	Uncharacterized protein		PANTR		391	UniRef100_A0A2I3SIC4
LUC7 like 2, pre-mRNA splicing factor		SAIBB		391
Uncharacterized protein		Cebus capucinus imitator		391
Uncharacterized protein		CERAT		391
Uncharacterized protein		AOTNA		391
+7
Q9Y383-3	Uncharacterized protein		MACMU		389	UniRef100_A0A1D5R338
LUC7 like 2, pre-mRNA splicing factor		SAIBB		389
Uncharacterized protein		CALJA		389
Uncharacterized protein		Cebus capucinus imitator		389
Uncharacterized protein		PANTR		389
+8

Protein	Similar proteins		Species	Score	Length	Source
Q9Y383	Putative RNA-binding protein Luc7-like 2		MOUSE		392	UniRef90_Q9Y383
Putative RNA-binding protein Luc7-like 2 isoform 1		CALJA		392
C7orf55-LUC7L2 readthrough		PANTR		392
LUC7 like 2, pre-mRNA splicing factor		SAIBB		392
Putative RNA-binding protein Luc7-like 2		MACMU		392
+142
Q9Y383-2	Uncharacterized protein		PANTR		391	UniRef90_A0A2I3SIC4
LUC7 like 2, pre-mRNA splicing factor		SAIBB		391
Uncharacterized protein		Cebus capucinus imitator		391
Uncharacterized protein		CERAT		391
Uncharacterized protein		AOTNA		391
+83
Q9Y383-3	Isoform 2 of Protein FMC1 homolog		HUMAN		458	UniRef90_Q96HJ9-2
Uncharacterized protein (Fragment)		MACMU		372
Uncharacterized protein (Fragment)		MACFA		372
Uncharacterized protein		FELCA		460
Uncharacterized protein		BOVIN		458
+106

Protein	Similar proteins		Species	Score	Length	Source
Q9Y383	Putative RNA-binding protein Luc7-like 2		MOUSE		392	UniRef50_Q9Y383
Putative RNA-binding protein Luc7-like 2 isoform 1		CALJA		392
C7orf55-LUC7L2 readthrough		PANTR		392
LUC7 like 2, pre-mRNA splicing factor		SAIBB		392
Putative RNA-binding protein Luc7-like 2		MACMU		392
+472

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF151817 mRNA Translation: AAD34054.1 AF151832 mRNA Translation: AAD34069.1 Frameshift. AK001476 mRNA Translation: BAA91713.1 AK001519 mRNA Translation: BAA91737.1 AK022895 mRNA Translation: BAB14297.1 AK298166 mRNA Translation: BAH12736.1 BC017163 mRNA Translation: AAH17163.1 BC042625 mRNA Translation: AAH42625.1 BC050708 mRNA Translation: AAH50708.1 BC056886 mRNA Translation: AAH56886.1
CCDSⁱ	CCDS43656.1 [Q9Y383-1] CCDS59085.1 [Q9Y383-3] CCDS59510.1 [Q9Y383-2]
RefSeqⁱ	NP_001231514.1, NM_001244585.1 [Q9Y383-3] NP_001257572.1, NM_001270643.1 [Q9Y383-2] NP_057103.2, NM_016019.4 [Q9Y383-1]
UniGeneⁱ	Hs.731488

3D structure databases

ProteinModelPortalⁱ	Q9Y383
SMRⁱ	Q9Y383
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	119646, 178 interactors
CORUMⁱ	Q9Y383
DIPⁱ	DIP-32513N
IntActⁱ	Q9Y383, 67 interactors
MINTⁱ	Q9Y383
STRINGⁱ	9606.ENSP00000347005

PTM databases

iPTMnetⁱ	Q9Y383
PhosphoSitePlusⁱ	Q9Y383
SwissPalmⁱ	Q9Y383

Polymorphism and mutation databases

BioMutaⁱ	LUC7L2
DMDMⁱ	47116960

Proteomic databases

EPDⁱ	Q9Y383
PaxDbⁱ	Q9Y383
PeptideAtlasⁱ	Q9Y383
PRIDEⁱ	Q9Y383
ProteomicsDBⁱ	85982 85983 [Q9Y383-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	51631
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000263545; ENSP00000263545; ENSG00000146963 [Q9Y383-3] ENST00000354926; ENSP00000347005; ENSG00000146963 [Q9Y383-1] ENST00000541170; ENSP00000441604; ENSG00000146963 [Q9Y383-3] ENST00000619796; ENSP00000483438; ENSG00000146963 [Q9Y383-2]
GeneIDⁱ	51631
KEGGⁱ	hsa:51631
UCSCⁱ	uc003vux.5 human [Q9Y383-1]

Organism-specific databases

CTDⁱ	51631
EuPathDBⁱ	HostDB:ENSG00000146963.17
GeneCardsⁱ	LUC7L2
HGNCⁱ	HGNC:21608 LUC7L2
HPAⁱ	HPA051631
MIMⁱ	613056 gene
neXtProtⁱ	NX_Q9Y383
OpenTargetsⁱ	ENSG00000146963
PharmGKBⁱ	PA134873425
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0796 Eukaryota COG5200 LUCA
GeneTreeⁱ	ENSGT00730000110670
HOVERGENⁱ	HBG062167
InParanoidⁱ	Q9Y383
KOⁱ	K13212
OrthoDBⁱ	EOG091G0PSO
PhylomeDBⁱ	Q9Y383
TreeFamⁱ	TF317607

Miscellaneous databases

ChiTaRSⁱ	LUC7L2 human
GeneWikiⁱ	LUC7L2
GenomeRNAiⁱ	51631
PMAP-CutDBⁱ	Q9Y383
Protein Ontology More...PROⁱ	PR:Q9Y383
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000146963 Expressed in 221 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_LUC7L2
ExpressionAtlasⁱ	Q9Y383 baseline and differential
Genevisibleⁱ	Q9Y383 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR004882 Luc7-rel
PANTHERⁱ	PTHR12375 PTHR12375, 1 hit
Pfamⁱ	View protein in Pfam PF03194 LUC7, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	LC7L2_HUMAN
Accessionⁱ	Q9Y383Primary (citable) accession number: Q9Y383 Secondary accession number(s): B7Z500 , Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
	Last sequence update:	May 10, 2004
	Last modified:	September 12, 2018
	This is version 156 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
SIMILARITY comments
Index of protein domains and families
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9Y383 (LC7L2_HUMAN)

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Putative RNA-binding protein Luc7-like 2

LUC7L2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

Miscellaneous databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ