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UniProtKB - Q9Y383 (LC7L2_HUMAN)

Entry version 171 (22 Apr 2020)
Sequence version 2 (10 May 2004)
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Protein

Putative RNA-binding protein Luc7-like 2

Gene

LUC7L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May bind to RNA via its Arg/Ser-rich domain.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative RNA-binding protein Luc7-like 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LUC7L2
ORF Names:CGI-59, CGI-74
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21608 LUC7L2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		613056 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y383

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi266K → R: Induces a decrease in lysyl-hydroxylation. Abolishes lysyl-hydroxylation; when associated with R-269. 1 Publication1
Mutagenesisi269K → R: Induces a decrease in lysyl-hydroxylation. Abolishes lysyl-hydroxylation; when associated with R-266. 1 Publication1

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000146963

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134873425

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y383 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LUC7L2

Domain mapping of disease mutations (DMDM)

More...DMDMi		47116960

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001872821 – 392Putative RNA-binding protein Luc7-like 2Add BLAST392

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18PhosphoserineCombined sources1
Modified residuei2665-hydroxylysine; by JMJD61 Publication1
Modified residuei2695-hydroxylysine; by JMJD61 Publication1

Keywords - PTMi

Hydroxylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y383

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y383

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y383

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y383

PeptideAtlas

More...PeptideAtlasi		Q9Y383

PRoteomics IDEntifications database

More...PRIDEi		Q9Y383

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		6647
85982 [Q9Y383-1]
85983 [Q9Y383-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y383

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q9Y383

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y383

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9Y383

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000146963 Expressed in left lobe of thyroid gland and 220 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y383 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y383 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000146963 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SCNM1.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		119646, 200 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9Y383

Database of interacting proteins

More...DIPi		DIP-32513N

Protein interaction database and analysis system

More...IntActi		Q9Y383, 123 interactors

Molecular INTeraction database

More...MINTi		Q9Y383

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000347005

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y383 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y383

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili102 – 177Sequence analysisAdd BLAST76

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi239 – 388Arg/Ser-richAdd BLAST150

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Luc7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0796 Eukaryota
COG5200 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183213

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_030397_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y383

KEGG Orthology (KO)

More...KOi		K13212

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y383

TreeFam database of animal gene trees

More...TreeFami		TF317607

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004882 Luc7-rel

The PANTHER Classification System

More...PANTHERi		PTHR12375 PTHR12375, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03194 LUC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y383-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAQAQMRAM LDQLMGTSRD GDTTRQRIKF SDDRVCKSHL LNCCPHDVLS 
        60         70         80         90        100
GTRMDLGECL KVHDLALRAD YEIASKEQDF FFELDAMDHL QSFIADCDRR 
       110        120        130        140        150
TEVAKKRLAE TQEEISAEVA AKAERVHELN EEIGKLLAKV EQLGAEGNVE 
       160        170        180        190        200
ESQKVMDEVE KARAKKREAE EVYRNSMPAS SFQQQKLRVC EVCSAYLGLH 
       210        220        230        240        250
DNDRRLADHF GGKLHLGFIE IREKLEELKR VVAEKQEKRN QERLKRREER 
       260        270        280        290        300
EREEREKLRR SRSHSKNPKR SRSREHRRHR SRSMSRERKR RTRSKSREKR 
       310        320        330        340        350
HRHRSRSSSR SRSRSHQRSR HSSRDRSRER SKRRSSKERF RDQDLASCDR 
       360        370        380        390 
DRSSRDRSPR DRDRKDKKRS YESANGRSED RRSSEEREAG EI
Length:392
Mass (Da):46,514
Last modified:May 10, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1C559CCE0F23F693
GO
Isoform 2 (identifier: Q9Y383-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-21: MSAQAQMRAMLDQLMGTSRDG → MPAYLNLQGSVRKAPHSPSR

Show »
Length:391
Mass (Da):46,425
Checksum:i68FBCFE447A3E0E5
GO
Isoform 3 (identifier: Q9Y383-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: MSAQAQMRAMLDQLMGTSRD → MVIHSQLKKIQGASERM

Show »
Length:389
Mass (Da):46,229
Checksum:iA58A74530C83E98E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A6YYJ8A0A0A6YYJ8_HUMAN
Putative RNA-binding protein Luc7-l...
LUC7L2
458Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEU3F8WEU3_HUMAN
Putative RNA-binding protein Luc7-l...
LUC7L2
83Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GZ75V9GZ75_HUMAN
Putative RNA-binding protein Luc7-l...
LUC7L2
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD34069 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27R → Q in BAA91737 (PubMed:14702039).Curated1
Sequence conflicti389 – 390AG → QR in AAD34054 (PubMed:10810093).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034067361D → E. Corresponds to variant dbSNP:rs3757435Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0102171 – 21MSAQA…TSRDG → MPAYLNLQGSVRKAPHSPSR in isoform 2. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_0448961 – 20MSAQA…GTSRD → MVIHSQLKKIQGASERM in isoform 3. 1 PublicationAdd BLAST20

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF151817 mRNA Translation: AAD34054.1
AF151832 mRNA Translation: AAD34069.1 Frameshift.
AK001476 mRNA Translation: BAA91713.1
AK001519 mRNA Translation: BAA91737.1
AK022895 mRNA Translation: BAB14297.1
AK298166 mRNA Translation: BAH12736.1
BC017163 mRNA Translation: AAH17163.1
BC042625 mRNA Translation: AAH42625.1
BC050708 mRNA Translation: AAH50708.1
BC056886 mRNA Translation: AAH56886.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS43656.1 [Q9Y383-1]
CCDS59085.1 [Q9Y383-3]
CCDS59510.1 [Q9Y383-2]

NCBI Reference Sequences

More...RefSeqi		NP_001231514.1, NM_001244585.1 [Q9Y383-3]
NP_001257572.1, NM_001270643.1 [Q9Y383-2]
NP_057103.2, NM_016019.4 [Q9Y383-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000263545; ENSP00000263545; ENSG00000146963 [Q9Y383-3]
ENST00000354926; ENSP00000347005; ENSG00000146963 [Q9Y383-1]
ENST00000541170; ENSP00000441604; ENSG00000146963 [Q9Y383-3]
ENST00000619796; ENSP00000483438; ENSG00000146963 [Q9Y383-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51631

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51631

UCSC genome browser

More...UCSCi		uc003vux.5 human [Q9Y383-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF151817 mRNA Translation: AAD34054.1
AF151832 mRNA Translation: AAD34069.1 Frameshift.
AK001476 mRNA Translation: BAA91713.1
AK001519 mRNA Translation: BAA91737.1
AK022895 mRNA Translation: BAB14297.1
AK298166 mRNA Translation: BAH12736.1
BC017163 mRNA Translation: AAH17163.1
BC042625 mRNA Translation: AAH42625.1
BC050708 mRNA Translation: AAH50708.1
BC056886 mRNA Translation: AAH56886.1
CCDSiCCDS43656.1 [Q9Y383-1]
CCDS59085.1 [Q9Y383-3]
CCDS59510.1 [Q9Y383-2]
RefSeqiNP_001231514.1, NM_001244585.1 [Q9Y383-3]
NP_001257572.1, NM_001270643.1 [Q9Y383-2]
NP_057103.2, NM_016019.4 [Q9Y383-1]

3D structure databases

SMRiQ9Y383
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119646, 200 interactors
CORUMiQ9Y383
DIPiDIP-32513N
IntActiQ9Y383, 123 interactors
MINTiQ9Y383
STRINGi9606.ENSP00000347005

PTM databases

iPTMnetiQ9Y383
MetOSiteiQ9Y383
PhosphoSitePlusiQ9Y383
SwissPalmiQ9Y383

Polymorphism and mutation databases

BioMutaiLUC7L2
DMDMi47116960

Proteomic databases

EPDiQ9Y383
jPOSTiQ9Y383
MassIVEiQ9Y383
PaxDbiQ9Y383
PeptideAtlasiQ9Y383
PRIDEiQ9Y383
ProteomicsDBi6647
85982 [Q9Y383-1]
85983 [Q9Y383-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		53629 131 antibodies

The DNASU plasmid repository

More...DNASUi		51631

Genome annotation databases

EnsembliENST00000263545; ENSP00000263545; ENSG00000146963 [Q9Y383-3]
ENST00000354926; ENSP00000347005; ENSG00000146963 [Q9Y383-1]
ENST00000541170; ENSP00000441604; ENSG00000146963 [Q9Y383-3]
ENST00000619796; ENSP00000483438; ENSG00000146963 [Q9Y383-2]
GeneIDi51631
KEGGihsa:51631
UCSCiuc003vux.5 human [Q9Y383-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51631

GeneCards: human genes, protein and diseases

More...GeneCardsi		LUC7L2
HGNCiHGNC:21608 LUC7L2
HPAiENSG00000146963 Low tissue specificity
MIMi613056 gene
neXtProtiNX_Q9Y383
OpenTargetsiENSG00000146963
PharmGKBiPA134873425

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0796 Eukaryota
COG5200 LUCA
GeneTreeiENSGT00950000183213
HOGENOMiCLU_030397_3_0_1
InParanoidiQ9Y383
KOiK13212
PhylomeDBiQ9Y383
TreeFamiTF317607

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		LUC7L2 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		LUC7L2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51631
PharosiQ9Y383 Tdark

Protein Ontology

More...PROi		PR:Q9Y383
RNActiQ9Y383 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000146963 Expressed in left lobe of thyroid gland and 220 other tissues
ExpressionAtlasiQ9Y383 baseline and differential
GenevisibleiQ9Y383 HS

Family and domain databases

InterProiView protein in InterPro
IPR004882 Luc7-rel
PANTHERiPTHR12375 PTHR12375, 1 hit
PfamiView protein in Pfam
PF03194 LUC7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLC7L2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y383
Secondary accession number(s): B7Z500
, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: April 22, 2020
This is version 171 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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