Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - Q9Y376 (CAB39_HUMAN)

Entry version 179 (23 Feb 2022)
Sequence version 1 (01 Nov 1999)
Previous versions | rss
Add a publicationFeedback
Protein

Calcium-binding protein 39

Gene

CAB39

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9Y376

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-380972, Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-6798695, Neutrophil degranulation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9Y376

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Calcium-binding protein 39
Alternative name(s):
MO25alpha
Protein Mo25
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAB39
Synonyms:MO25
ORF Names:CGI-66
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20292, CAB39

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612174, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y376

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000135932

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi240R → A: Abolishes activation of STK11/LKB1; when associated with A-243. 1 Publication1
Mutagenesisi243F → A: Abolishes activation of STK11/LKB1; when associated with A-240. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		51719

Open Targets

More...OpenTargetsi		ENSG00000135932

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA128394663

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y376, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL3885534

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CAB39

Domain mapping of disease mutations (DMDM)

More...DMDMi		15214082

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002098241 – 341Calcium-binding protein 39Add BLAST341

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y376

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y376

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y376

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Y376

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y376

PeptideAtlas

More...PeptideAtlasi		Q9Y376

PRoteomics IDEntifications database

More...PRIDEi		Q9Y376

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		85981

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y376

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y376

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000135932, Expressed in middle temporal gyrus and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y376, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y376, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000135932, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119696, 62 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-2845, LKB1-STRAD-MO25 serine/threonine protein kinase complex, CAB39-STRADA variant
CPX-2868, LKB1-STRAD-MO25 serine/threonine protein kinase complex, CAB39-STRADB variant

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9Y376

Database of interacting proteins

More...DIPi		DIP-31316N

Protein interaction database and analysis system

More...IntActi		Q9Y376, 24 interactors

Molecular INTeraction database

More...MINTi		Q9Y376

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000258418

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y376, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1341
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y376

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9Y376

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Mo25 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1566, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000004360

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_035755_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y376

Identification of Orthologs from Complete Genome Data

More...OMAi		HLKLCMN

Database of Orthologous Groups

More...OrthoDBi		865327at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y376

TreeFam database of animal gene trees

More...TreeFami		TF314910

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR013878, Mo25

The PANTHER Classification System

More...PANTHERi		PTHR10182, PTHR10182, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08569, Mo25, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y376-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM 
        60         70         80         90        100
KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ 
       110        120        130        140        150
IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC 
       160        170        180        190        200
IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA 
       210        220        230        240        250
EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI 
       260        270        280        290        300
SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA 
       310        320        330        340 
KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A
Length:341
Mass (Da):39,869
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEC710A528B6F9811
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X0K1A0A087X0K1_HUMAN
Calcium-binding protein 39
CAB39
339Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF151824 mRNA Translation: AAD34061.1
AF113536 mRNA Translation: AAF14873.1
AK292382 mRNA Translation: BAF85071.1
AK315692 mRNA Translation: BAG38055.1
CH471063 Genomic DNA Translation: EAW70932.1
BC020570 mRNA Translation: AAH20570.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2478.1

NCBI Reference Sequences

More...RefSeqi		NP_001124321.1, NM_001130849.1
NP_001124322.1, NM_001130850.1
NP_057373.1, NM_016289.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000258418; ENSP00000258418; ENSG00000135932
ENST00000409788; ENSP00000386238; ENSG00000135932
ENST00000410084; ENSP00000386642; ENSG00000135932

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51719

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51719

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000258418.10; ENSP00000258418.5; NM_016289.4; NP_057373.1

UCSC genome browser

More...UCSCi		uc002vqx.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF151824 mRNA Translation: AAD34061.1
AF113536 mRNA Translation: AAF14873.1
AK292382 mRNA Translation: BAF85071.1
AK315692 mRNA Translation: BAG38055.1
CH471063 Genomic DNA Translation: EAW70932.1
BC020570 mRNA Translation: AAH20570.1
CCDSiCCDS2478.1
RefSeqiNP_001124321.1, NM_001130849.1
NP_001124322.1, NM_001130850.1
NP_057373.1, NM_016289.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UPKX-ray1.85A1-341[»]
1UPLX-ray2.60A/B1-341[»]
2WTKX-ray2.65A/D1-341[»]
3GNIX-ray2.35A1-341[»]
4FZAX-ray3.15A11-334[»]
4FZDX-ray3.25A11-334[»]
4FZFX-ray3.64A11-334[»]
4NZWX-ray3.58A8-334[»]
4O27X-ray3.18A11-333[»]
SMRiQ9Y376
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi119696, 62 interactors
ComplexPortaliCPX-2845, LKB1-STRAD-MO25 serine/threonine protein kinase complex, CAB39-STRADA variant
CPX-2868, LKB1-STRAD-MO25 serine/threonine protein kinase complex, CAB39-STRADB variant
CORUMiQ9Y376
DIPiDIP-31316N
IntActiQ9Y376, 24 interactors
MINTiQ9Y376
STRINGi9606.ENSP00000258418

Chemistry databases

ChEMBLiCHEMBL3885534

PTM databases

iPTMnetiQ9Y376
PhosphoSitePlusiQ9Y376

Genetic variation databases

BioMutaiCAB39
DMDMi15214082

Proteomic databases

EPDiQ9Y376
jPOSTiQ9Y376
MassIVEiQ9Y376
MaxQBiQ9Y376
PaxDbiQ9Y376
PeptideAtlasiQ9Y376
PRIDEiQ9Y376
ProteomicsDBi85981

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		34407, 148 antibodies from 27 providers

The DNASU plasmid repository

More...DNASUi		51719

Genome annotation databases

EnsembliENST00000258418; ENSP00000258418; ENSG00000135932
ENST00000409788; ENSP00000386238; ENSG00000135932
ENST00000410084; ENSP00000386642; ENSG00000135932
GeneIDi51719
KEGGihsa:51719
MANE-SelectiENST00000258418.10; ENSP00000258418.5; NM_016289.4; NP_057373.1
UCSCiuc002vqx.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51719
DisGeNETi51719

GeneCards: human genes, protein and diseases

More...GeneCardsi		CAB39
HGNCiHGNC:20292, CAB39
HPAiENSG00000135932, Tissue enhanced (skeletal)
MIMi612174, gene
neXtProtiNX_Q9Y376
OpenTargetsiENSG00000135932
PharmGKBiPA128394663
VEuPathDBiHostDB:ENSG00000135932

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1566, Eukaryota
GeneTreeiENSGT00390000004360
HOGENOMiCLU_035755_0_0_1
InParanoidiQ9Y376
OMAiHLKLCMN
OrthoDBi865327at2759
PhylomeDBiQ9Y376
TreeFamiTF314910

Enzyme and pathway databases

PathwayCommonsiQ9Y376
ReactomeiR-HSA-380972, Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-6798695, Neutrophil degranulation
SignaLinkiQ9Y376

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51719, 194 hits in 1055 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CAB39, human
EvolutionaryTraceiQ9Y376

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CAB39

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51719
PharosiQ9Y376, Tbio

Protein Ontology

More...PROi		PR:Q9Y376
RNActiQ9Y376, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000135932, Expressed in middle temporal gyrus and 242 other tissues
ExpressionAtlasiQ9Y376, baseline and differential
GenevisibleiQ9Y376, HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR013878, Mo25
PANTHERiPTHR10182, PTHR10182, 1 hit
PfamiView protein in Pfam
PF08569, Mo25, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAB39_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y376
Secondary accession number(s): A8K8L7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: November 1, 1999
Last modified: February 23, 2022
This is version 179 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again