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Entry version 137 (12 Aug 2020)
Sequence version 4 (20 Apr 2010)
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Protein

von Willebrand factor A domain-containing protein 7

Gene

VWA7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Found in the major hispocompatibility complex class III region. May be implicated in susceptibility to lung tumors.

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9Y334

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
von Willebrand factor A domain-containing protein 7
Alternative name(s):
Protein G7c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:VWA7
Synonyms:C6orf27, G7C, NG37
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000204396.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13939, VWA7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609693, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y334

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80737

Open Targets

More...
OpenTargetsi
ENSG00000204396

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25928

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y334, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
VWA7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
294862535

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000023163129 – 891von Willebrand factor A domain-containing protein 7Add BLAST863

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi55N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y334

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y334

PeptideAtlas

More...
PeptideAtlasi
Q9Y334

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y334

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85968 [Q9Y334-1]
85969 [Q9Y334-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9Y334, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y334

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y334

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at low level in different cell lines.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000204396, Expressed in pituitary gland and 110 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y334, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y334, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000204396, Tissue enhanced (fallopian tube, pituitary gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123282, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y334, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364840

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y334, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini313 – 506VWFAAdd BLAST194

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4475, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011517

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013884_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y334

Identification of Orthologs from Complete Genome Data

More...
OMAi
MEPIHYV

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y334

TreeFam database of animal gene trees

More...
TreeFami
TF329905

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036465, vWFA_dom_sf

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300, SSF53300, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y334-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLPTEVPQSH PGPSALLLLQ LLLPPTSAFF PNIWSLLAAP GSITHQDLTE
60 70 80 90 100
EAALNVTLQL FLEQPPPGRP PLRLEDFLGR TLLADDLFAA YFGPGSSRRF
110 120 130 140 150
RAALGEVSRA NAAQDFLPTS RNDPDLHFDA ERLGQGRARL VGALRETVVA
160 170 180 190 200
ARALDHTLAR QRLGAALHAL QDFYSHSNWV ELGEQQPHPH LLWPRQELQN
210 220 230 240 250
LAQVADPTCS DCEELSCPRN WLGFTLLTSG YFGTHPPKPP GKCSHGGHFD
260 270 280 290 300
RSSSQPPRGG INKDSTSPGF SPHHMLHLQA AKLALLASIQ AFSLLRSRLG
310 320 330 340 350
DRDFSRLLDI TPASSLSFVL DTTGSMGEEI NAAKIQARHL VEQRRGSPME
360 370 380 390 400
PVHYVLVPFH DPGFGPVFTT SDPDSFWQQL NEIHALGGGD EPEMCLSALQ
410 420 430 440 450
LALLHTPPLS DIFVFTDASP KDAFLTNQVE SLTQERRCRV TFLVTEDTSR
460 470 480 490 500
VQGRARREIL SPLRFEPYKA VALASGGEVI FTKDQHIRDV AAIVGESMAA
510 520 530 540 550
LVTLPLDPPV VVPGQPLVFS VDGLLQKITV RIHGDISSFW IKNPAGVSQG
560 570 580 590 600
QEEGGGPLGH TRRFGQFWMV TMDDPPQTGT WEIQVTAEDT PGVRVQAQTS
610 620 630 640 650
LDFLFHFGIP MEDGPHPGLY PLTQPVAGLQ TQLLVEVTGL GSRANPGDPQ
660 670 680 690 700
PHFSHVILRG VPEGAELGQV PLEPVGPPER GLLAASLSPT LLSTPRPFSL
710 720 730 740 750
ELIGQDAAGR RLHRAAPQPS TVVPVLLELS GPSGFLAPGS KVPLSLRIAS
760 770 780 790 800
FSGPQDLDLR TFVNPSFSLT SNLSRAHLEL NESAWGRLWL EVPDSAAPDS
810 820 830 840 850
VVMVTVTAGG REANPVPPTH AFLRLLVSAP APQDRHTTPT GSSDPILTTA
860 870 880 890
TPAFSPFTLV TQGRAGAGLA AGSPWWGTVG GVLLLLGLAS W
Length:891
Mass (Da):96,060
Last modified:April 20, 2010 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFAA559F2B63752FF
GO
Isoform 2 (identifier: Q9Y334-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     834-860: DRHTTPTGSSDPILTTATPAFSPFTLV → VRNHYFPSQGPAHHPYRLI
     861-891: Missing.

Show »
Length:852
Mass (Da):92,513
Checksum:i1E2430B3F912A954
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A140T9S5A0A140T9S5_HUMAN
VWA7
VWA7
891Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB52192 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 2 (identifier: Q9Y334-2)
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti837H → Y in AAD21820 (PubMed:14656967).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056884139R → H. Corresponds to variant dbSNP:rs17207531Ensembl.1
Natural variantiVAR_056885488R → Q. Corresponds to variant dbSNP:rs11966331Ensembl.1
Natural variantiVAR_056886680R → Q. Corresponds to variant dbSNP:rs28400004Ensembl.1
Natural variantiVAR_056887704G → V. Corresponds to variant dbSNP:rs28400002Ensembl.1
Natural variantiVAR_056888711R → C. Corresponds to variant dbSNP:rs28400001Ensembl.1
Natural variantiVAR_060378861T → A1 PublicationCorresponds to variant dbSNP:rs3101017Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026494834 – 860DRHTT…PFTLV → VRNHYFPSQGPAHHPYRLI in isoform 2. 1 PublicationAdd BLAST27
Alternative sequenceiVSP_026495861 – 891Missing in isoform 2. 1 PublicationAdd BLAST31

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF134726 Genomic DNA Translation: AAD21820.1
BA000025 Genomic DNA Translation: BAB63304.1
AL662834 Genomic DNA No translation available.
AL662899 Genomic DNA No translation available.
BX248133 Genomic DNA No translation available.
CR759787 Genomic DNA No translation available.
CR759915 Genomic DNA No translation available.
CR925765 Genomic DNA No translation available.
AJ245418 mRNA Translation: CAB52192.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4721.2 [Q9Y334-1]

NCBI Reference Sequences

More...
RefSeqi
NP_079534.2, NM_025258.2 [Q9Y334-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375688; ENSP00000364840; ENSG00000204396 [Q9Y334-1]
ENST00000430726; ENSP00000411910; ENSG00000234433 [Q9Y334-1]
ENST00000438415; ENSP00000390732; ENSG00000230048 [Q9Y334-1]
ENST00000438725; ENSP00000413704; ENSG00000223757 [Q9Y334-1]
ENST00000452329; ENSP00000406943; ENSG00000238203 [Q9Y334-1]
ENST00000550450; ENSP00000450313; ENSG00000227144

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80737

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80737

UCSC genome browser

More...
UCSCi
uc011dog.3, human [Q9Y334-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF134726 Genomic DNA Translation: AAD21820.1
BA000025 Genomic DNA Translation: BAB63304.1
AL662834 Genomic DNA No translation available.
AL662899 Genomic DNA No translation available.
BX248133 Genomic DNA No translation available.
CR759787 Genomic DNA No translation available.
CR759915 Genomic DNA No translation available.
CR925765 Genomic DNA No translation available.
AJ245418 mRNA Translation: CAB52192.1 Frameshift.
CCDSiCCDS4721.2 [Q9Y334-1]
RefSeqiNP_079534.2, NM_025258.2 [Q9Y334-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi123282, 2 interactors
IntActiQ9Y334, 1 interactor
STRINGi9606.ENSP00000364840

PTM databases

GlyGeniQ9Y334, 1 site
iPTMnetiQ9Y334
PhosphoSitePlusiQ9Y334

Polymorphism and mutation databases

BioMutaiVWA7
DMDMi294862535

Proteomic databases

MassIVEiQ9Y334
PaxDbiQ9Y334
PeptideAtlasiQ9Y334
PRIDEiQ9Y334
ProteomicsDBi85968 [Q9Y334-1]
85969 [Q9Y334-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
56596, 14 antibodies

The DNASU plasmid repository

More...
DNASUi
80737

Genome annotation databases

EnsembliENST00000375688; ENSP00000364840; ENSG00000204396 [Q9Y334-1]
ENST00000430726; ENSP00000411910; ENSG00000234433 [Q9Y334-1]
ENST00000438415; ENSP00000390732; ENSG00000230048 [Q9Y334-1]
ENST00000438725; ENSP00000413704; ENSG00000223757 [Q9Y334-1]
ENST00000452329; ENSP00000406943; ENSG00000238203 [Q9Y334-1]
ENST00000550450; ENSP00000450313; ENSG00000227144
GeneIDi80737
KEGGihsa:80737
UCSCiuc011dog.3, human [Q9Y334-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80737
DisGeNETi80737
EuPathDBiHostDB:ENSG00000204396.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
VWA7
HGNCiHGNC:13939, VWA7
HPAiENSG00000204396, Tissue enhanced (fallopian tube, pituitary gland)
MIMi609693, gene
neXtProtiNX_Q9Y334
OpenTargetsiENSG00000204396
PharmGKBiPA25928

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4475, Eukaryota
GeneTreeiENSGT00390000011517
HOGENOMiCLU_013884_0_0_1
InParanoidiQ9Y334
OMAiMEPIHYV
PhylomeDBiQ9Y334
TreeFamiTF329905

Enzyme and pathway databases

PathwayCommonsiQ9Y334

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
80737, 15 hits in 866 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
VWA7, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80737
PharosiQ9Y334, Tdark

Protein Ontology

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PROi
PR:Q9Y334
RNActiQ9Y334, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000204396, Expressed in pituitary gland and 110 other tissues
ExpressionAtlasiQ9Y334, baseline and differential
GenevisibleiQ9Y334, HS

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR036465, vWFA_dom_sf
SUPFAMiSSF53300, SSF53300, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVWA7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y334
Secondary accession number(s): A2BEX8
, A6NHR6, B0V041, Q5SSR5, Q96QC8, Q9UMP9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 20, 2010
Last modified: August 12, 2020
This is version 137 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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