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Entry version 135 (13 Nov 2019)
Sequence version 5 (22 Nov 2017)
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Protein

Proton-associated sugar transporter A

Gene

SLC45A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proton-associated glucose transporter in the brain.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Symport, Transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.2.4.10 the glycoside-pentoside-hexuronide (gph):cation symporter family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proton-associated sugar transporter A
Short name:
PAST-A
Alternative name(s):
Deleted in neuroblastoma 5 protein
Short name:
DNb-5
Solute carrier family 45 member 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC45A1
Synonyms:DNB5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17939 SLC45A1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605763 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y2W3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Transmembranei189 – 209HelicalSequence analysisAdd BLAST21
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21
Transmembranei267 – 287HelicalSequence analysisAdd BLAST21
Transmembranei302 – 322HelicalSequence analysisAdd BLAST21
Transmembranei567 – 587HelicalSequence analysisAdd BLAST21
Transmembranei607 – 627HelicalSequence analysisAdd BLAST21
Transmembranei634 – 654HelicalSequence analysisAdd BLAST21
Transmembranei661 – 681HelicalSequence analysisAdd BLAST21
Transmembranei719 – 739HelicalSequence analysisAdd BLAST21
Transmembranei742 – 762HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Intellectual developmental disorder with neuropsychiatric features (IDDNPF)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive disorder characterized by moderate to severe intellectual disability, epilepsy, and variable neuropsychiatric features, such as anxiety, obsessive-compulsive behavior, and autistic features. Mild facial dysmorphism may also be present.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07934490I → T in IDDNPF; no effect on protein abundance; no effect on glucose transport activity. 2 PublicationsCorresponds to variant dbSNP:rs141816307Ensembl.1
Natural variantiVAR_079345210R → W in IDDNPF; no effect on protein abundance; decreased glucose transport activity. 1 PublicationCorresponds to variant dbSNP:rs781036625EnsemblClinVar.1
Natural variantiVAR_079346244A → V in IDDNPF; no effect on protein abundance; decreased glucose transport activity. 1 PublicationCorresponds to variant dbSNP:rs150539474EnsemblClinVar.1

Keywords - Diseasei

Disease mutation, Epilepsy, Mental retardation

Organism-specific databases

DisGeNET

More...
DisGeNETi
50651

MalaCards human disease database

More...
MalaCardsi
SLC45A1
MIMi617532 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000162426

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
88616 Autosomal recessive non-syndromic intellectual disability

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y2W3

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC45A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033543

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001225141 – 782Proton-associated sugar transporter AAdd BLAST782

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei531PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y2W3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y2W3

PeptideAtlas

More...
PeptideAtlasi
Q9Y2W3

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y2W3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85916

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y2W3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y2W3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in adult heart, brain, muscle and kidney, with very strong expression in brain. Also expressed in fetal brain, kidney and lung.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162426 Expressed in 103 organ(s), highest expression level in cerebellum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y2W3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y2W3 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9Y2W3, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000289877

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0637 Eukaryota
ENOG410Y28T LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182914

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231090

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y2W3

KEGG Orthology (KO)

More...
KOi
K15378

Identification of Orthologs from Complete Genome Data

More...
OMAi
CSTICHM

Database of Orthologous Groups

More...
OrthoDBi
1230185at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y2W3

TreeFam database of animal gene trees

More...
TreeFami
TF325412

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011701 MFS
IPR036259 MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07690 MFS_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y2W3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLQQPGPRPG RQQPSGDRDA CRLHPQGRPP ALPTMIPAAS STPPGDALFP
60 70 80 90 100
SVAPQDFWRS QVTGYSGSVT RHLSHRANNF KRHPKRRKCI RPSPPPPPNT
110 120 130 140 150
PCPLELVDFG DLHPQRSFRE LLFNGCILFG IEFSYAMETA YVTPVLLQMG
160 170 180 190 200
LPDQLYSLVW FISPILGFLL QPLLGAWSDR CTSRFGRRRP FILVLAIGAL
210 220 230 240 250
LGLSLLLNGR DIGIALADVT GNHKWGLLLT VCGVVLMDFS ADSADNPSHA
260 270 280 290 300
YMMDVCSPAD QDRGLNIHAL LAGLGGGFGY VVGGIHWDKT GFGRALGGQL
310 320 330 340 350
RVIYLFTAVT LSVTTVLTLV SIPERPLRPP SEKRAAMKSP SLPLPPSPPV
360 370 380 390 400
LPEEGPGDSL PSHTATNFSS PISPPSPLTP KYGSFISRDS SLTGISEFAS
410 420 430 440 450
SFGTANIDSV LIDCFTGGHD SYLAIPGSVP RPPISVSFPR APDGFYRQDR
460 470 480 490 500
GLLEGREGAL TSGCDGDILR VGSLDTSKPR SSGILKRPQT LAIPDAAGGG
510 520 530 540 550
GPETSRRRNV TFSQQVANIL LNGVKYESEL TGSSERAEQP LSVGRLCSTI
560 570 580 590 600
CNMPKALRTL CVNHFLGWLS FEGMLLFYTD FMGEVVFQGD PKAPHTSEAY
610 620 630 640 650
QKYNSGVTMG CWGMCIYAFS AAFYSAILEK LEEFLSVRTL YFIAYLAFGL
660 670 680 690 700
GTGLATLSRN LYVVLSLCIT YGILFSTLCT LPYSLLCDYY QSKKFAGSSA
710 720 730 740 750
DGTRRGMGVD ISLLSCQYFL AQILVSLVLG PLTSAVGSAN GVMYFSSLVS
760 770 780
FLGCLYSSLF VIYEIPPSDA ADEEHRPLLL NV
Length:782
Mass (Da):84,541
Last modified:November 22, 2017 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC841FDE4159A2DB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2H2EQP0A0A2H2EQP0_HUMAN
Proton-associated sugar transporter...
SLC45A1
748Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD27583 differs from that shown. Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti282V → L in AAD27583 (PubMed:10729226).Curated1
Sequence conflicti300L → F in AAD27583 (PubMed:10729226).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_07934490I → T in IDDNPF; no effect on protein abundance; no effect on glucose transport activity. 2 PublicationsCorresponds to variant dbSNP:rs141816307Ensembl.1
Natural variantiVAR_079345210R → W in IDDNPF; no effect on protein abundance; decreased glucose transport activity. 1 PublicationCorresponds to variant dbSNP:rs781036625EnsemblClinVar.1
Natural variantiVAR_079346244A → V in IDDNPF; no effect on protein abundance; decreased glucose transport activity. 1 PublicationCorresponds to variant dbSNP:rs150539474EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL356072 Genomic DNA No translation available.
CH471130 Genomic DNA Translation: EAW71597.1
AF118274 mRNA Translation: AAD27583.1 Sequence problems.

NCBI Reference Sequences

More...
RefSeqi
NP_001073866.2, NM_001080397.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000471889; ENSP00000418096; ENSG00000162426

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
50651

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:50651

UCSC genome browser

More...
UCSCi
uc001apb.3 human
uc057byt.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356072 Genomic DNA No translation available.
CH471130 Genomic DNA Translation: EAW71597.1
AF118274 mRNA Translation: AAD27583.1 Sequence problems.
RefSeqiNP_001073866.2, NM_001080397.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9Y2W3, 1 interactor
STRINGi9606.ENSP00000289877

Protein family/group databases

TCDBi2.A.2.4.10 the glycoside-pentoside-hexuronide (gph):cation symporter family

PTM databases

iPTMnetiQ9Y2W3
PhosphoSitePlusiQ9Y2W3

Polymorphism and mutation databases

BioMutaiSLC45A1
DMDMi311033543

Proteomic databases

jPOSTiQ9Y2W3
PaxDbiQ9Y2W3
PeptideAtlasiQ9Y2W3
PRIDEiQ9Y2W3
ProteomicsDBi85916

Genome annotation databases

EnsembliENST00000471889; ENSP00000418096; ENSG00000162426
GeneIDi50651
KEGGihsa:50651
UCSCiuc001apb.3 human
uc057byt.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
50651
DisGeNETi50651

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC45A1
HGNCiHGNC:17939 SLC45A1
MalaCardsiSLC45A1
MIMi605763 gene
617532 phenotype
neXtProtiNX_Q9Y2W3
OpenTargetsiENSG00000162426
Orphaneti88616 Autosomal recessive non-syndromic intellectual disability

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0637 Eukaryota
ENOG410Y28T LUCA
GeneTreeiENSGT00950000182914
HOGENOMiHOG000231090
InParanoidiQ9Y2W3
KOiK15378
OMAiCSTICHM
OrthoDBi1230185at2759
PhylomeDBiQ9Y2W3
TreeFamiTF325412

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC45A1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
50651
PharosiQ9Y2W3

Protein Ontology

More...
PROi
PR:Q9Y2W3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000162426 Expressed in 103 organ(s), highest expression level in cerebellum
ExpressionAtlasiQ9Y2W3 baseline and differential
GenevisibleiQ9Y2W3 HS

Family and domain databases

InterProiView protein in InterPro
IPR011701 MFS
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS45A1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2W3
Secondary accession number(s): A0A0A0MT80, Q5VY46, Q5VY49
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: November 22, 2017
Last modified: November 13, 2019
This is version 135 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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