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Protein

WW domain-binding protein 11

Gene

WBP11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • RNA binding Source: UniProtKB
  • single-stranded DNA binding Source: ProtInc
  • WW domain binding Source: UniProtKB

GO - Biological processi

  • mRNA cis splicing, via spliceosome Source: GO_Central
  • mRNA splicing, via spliceosome Source: Reactome
  • rRNA processing Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing, mRNA splicing, rRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-72163 mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WW domain-binding protein 11
Short name:
WBP-11
Alternative name(s):
Npw38-binding protein
Short name:
NpwBP
SH3 domain-binding protein SNP70
Splicing factor that interacts with PQBP-1 and PP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WBP11
Synonyms:NPWBP, SIPP1, SNP70
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000084463.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16461 WBP11

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618083 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y2W2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi192R → A: Loss of PQBP1-binding; when associated with A-197 and A-198. 1 Publication1
Mutagenesisi197R → A: Loss of PQBP1-binding; when associated with A-192 and A-198. 1 Publication1
Mutagenesisi198K → A: Loss of PQBP1-binding; when associated with A-192 and A-197. 1 Publication1

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000084463

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38144

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
WBP11

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74735242

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000659451 – 641WW domain-binding protein 11Add BLAST641

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei13N6-acetyllysineCombined sources1
Modified residuei181PhosphoserineCombined sources1
Modified residuei192Omega-N-methylarginineCombined sources1
Modified residuei236PhosphotyrosineBy similarity1
Modified residuei237PhosphoserineCombined sources1
Modified residuei279PhosphoserineCombined sources1
Modified residuei283PhosphoserineCombined sources1
Modified residuei353PhosphoserineCombined sources1
Modified residuei361PhosphoserineCombined sources1
Modified residuei364PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki557Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei565N6-acetyllysineBy similarity1
Cross-linki572Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei600PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y2W2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y2W2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y2W2

PeptideAtlas

More...
PeptideAtlasi
Q9Y2W2

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y2W2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85915

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y2W2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y2W2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000084463 Expressed in 233 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_WBP11

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y2W2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y2W2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039710
HPA040037
HPA046403
HPA049126

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PPP1CA, PPP1CB and PPP1CC (By similarity). Interacts via the PGR motif with PQBP1 in the nucleus. Interacts with the WW domains of WBP4.By similarity3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119702, 55 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9Y2W2

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
Q9Y2W2

Protein interaction database and analysis system

More...
IntActi
Q9Y2W2, 38 interactors

Molecular INTeraction database

More...
MINTi
Q9Y2W2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000261167

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Y2W2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y2W2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45Required for nuclear importBy similarityAdd BLAST45
Regioni217 – 221Interaction with PP1By similarity5
Regioni306 – 310Interaction with PP1By similarity5

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili75 – 133Sequence analysisAdd BLAST59

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi455 – 466PGRAdd BLAST12

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi140 – 209Pro-richAdd BLAST70
Compositional biasi246 – 297Asp-richAdd BLAST52
Compositional biasi319 – 322Poly-Lys4
Compositional biasi393 – 538Pro-richAdd BLAST146

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4672 Eukaryota
ENOG41115S5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163936

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154840

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG056793

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y2W2

KEGG Orthology (KO)

More...
KOi
K12866

Identification of Orthologs from Complete Genome Data

More...
OMAi
WADLKRK

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0BKC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y2W2

TreeFam database of animal gene trees

More...
TreeFami
TF323226

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019007 WW_dom-bd_prot_11

The PANTHER Classification System

More...
PANTHERi
PTHR13361 PTHR13361, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09429 Wbp11, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9Y2W2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRRSTSSTK SGKFMNPTDQ ARKEARKREL KKNKKQRMMV RAAVLKMKDP
60 70 80 90 100
KQIIRDMEKL DEMEFNPVQQ PQLNEKVLKD KRKKLRETFE RILRLYEKEN
110 120 130 140 150
PDIYKELRKL EVEYEQKRAQ LSQYFDAVKN AQHVEVESIP LPDMPHAPSN
160 170 180 190 200
ILIQDIPLPG AQPPSILKKT SAYGPPTRAV SILPLLGHGV PRLPPGRKPP
210 220 230 240 250
GPPPGPPPPQ VVQMYGRKVG FALDLPPRRR DEDMLYSPEL AQRGHDDDVS
260 270 280 290 300
STSEDDGYPE DMDQDKHDDS TDDSDTDKSD GESDGDEFVH RDNGERDNNE
310 320 330 340 350
EKKSGLSVRF ADMPGKSRKK KKNMKELTPL QAMMLRMAGQ EIPEEGREVE
360 370 380 390 400
EFSEDDDEDD SDDSEAEKQS QKQHKEESHS DGTSTASSQQ QAPPQSVPPS
410 420 430 440 450
QIQAPPMPGP PPLGPPPAPP LRPPGPPTGL PPGPPPGAPP FLRPPGMPGL
460 470 480 490 500
RGPLPRLLPP GPPPGRPPGP PPGPPPGLPP GPPPRGPPPR LPPPAPPGIP
510 520 530 540 550
PPRPGMMRPP LVPPLGPAPP GLFPPAPLPN PGVLSAPPNL IQRPKADDTS
560 570 580 590 600
AATIEKKATA TISAKPQITN PKAEITRFVP TALRVRRENK GATAAPQRKS
610 620 630 640
EDDSAVPLAK AAPKSGPSVP VSVQTKDDVY EAFMKEMEGL L
Length:641
Mass (Da):69,998
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC94F9687D132CE77
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H5G4F5H5G4_HUMAN
WW domain-binding protein 11
WBP11
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GXS9F5GXS9_HUMAN
WW domain-binding protein 11
WBP11
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB029309 mRNA Translation: BAA88410.1
AF118023 mRNA Translation: AAD30425.1
BC001621 mRNA Translation: AAH01621.1
BC016441 mRNA Translation: AAH16441.2
BC023532 mRNA Translation: AAH23532.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS8666.1

NCBI Reference Sequences

More...
RefSeqi
NP_057396.1, NM_016312.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.655138

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000261167; ENSP00000261167; ENSG00000084463

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51729

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51729

UCSC genome browser

More...
UCSCi
uc001rci.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB029309 mRNA Translation: BAA88410.1
AF118023 mRNA Translation: AAD30425.1
BC001621 mRNA Translation: AAH01621.1
BC016441 mRNA Translation: AAH16441.2
BC023532 mRNA Translation: AAH23532.1
CCDSiCCDS8666.1
RefSeqiNP_057396.1, NM_016312.2
UniGeneiHs.655138

3D structure databases

ProteinModelPortaliQ9Y2W2
SMRiQ9Y2W2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119702, 55 interactors
CORUMiQ9Y2W2
ELMiQ9Y2W2
IntActiQ9Y2W2, 38 interactors
MINTiQ9Y2W2
STRINGi9606.ENSP00000261167

PTM databases

iPTMnetiQ9Y2W2
PhosphoSitePlusiQ9Y2W2

Polymorphism and mutation databases

BioMutaiWBP11
DMDMi74735242

Proteomic databases

EPDiQ9Y2W2
MaxQBiQ9Y2W2
PaxDbiQ9Y2W2
PeptideAtlasiQ9Y2W2
PRIDEiQ9Y2W2
ProteomicsDBi85915

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51729
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000261167; ENSP00000261167; ENSG00000084463
GeneIDi51729
KEGGihsa:51729
UCSCiuc001rci.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51729
EuPathDBiHostDB:ENSG00000084463.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
WBP11
HGNCiHGNC:16461 WBP11
HPAiHPA039710
HPA040037
HPA046403
HPA049126
MIMi618083 gene
neXtProtiNX_Q9Y2W2
OpenTargetsiENSG00000084463
PharmGKBiPA38144

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4672 Eukaryota
ENOG41115S5 LUCA
GeneTreeiENSGT00940000163936
HOGENOMiHOG000154840
HOVERGENiHBG056793
InParanoidiQ9Y2W2
KOiK12866
OMAiWADLKRK
OrthoDBiEOG091G0BKC
PhylomeDBiQ9Y2W2
TreeFamiTF323226

Enzyme and pathway databases

ReactomeiR-HSA-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
WBP11 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
WBP11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51729

Protein Ontology

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PROi
PR:Q9Y2W2

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000084463 Expressed in 233 organ(s), highest expression level in testis
CleanExiHS_WBP11
ExpressionAtlasiQ9Y2W2 baseline and differential
GenevisibleiQ9Y2W2 HS

Family and domain databases

InterProiView protein in InterPro
IPR019007 WW_dom-bd_prot_11
PANTHERiPTHR13361 PTHR13361, 2 hits
PfamiView protein in Pfam
PF09429 Wbp11, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWBP11_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2W2
Secondary accession number(s): Q96AY8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: November 1, 1999
Last modified: December 5, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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