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UniProtKB - Q9Y2V2 (CHSP1_HUMAN)

Entry version 173 (25 May 2022)
Sequence version 2 (16 Jan 2004)
Previous versions | rss
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Protein

Calcium-regulated heat-stable protein 1

Gene

CARHSP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro).

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9Y2V2

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9Y2V2

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q9Y2V2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Calcium-regulated heat-stable protein 1
Alternative name(s):
Calcium-regulated heat-stable protein of 24 kDa
Short name:
CRHSP-24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CARHSP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:17150, CARHSP1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		616885, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y2V2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000153048

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi41S → D: Reduced affinity for single-stranded DNA. Abolishes location at cytoplasmic stress granules. 1 Publication1
Mutagenesisi76H → Q: Reduced affinity for single-stranded DNA. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		23589

Open Targets

More...OpenTargetsi		ENSG00000153048

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38440

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y2V2, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CARHSP1

Domain mapping of disease mutations (DMDM)

More...DMDMi		41016932

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001002302 – 147Calcium-regulated heat-stable protein 1Add BLAST146

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei30PhosphoserineCombined sources1 Publication1
Modified residuei32PhosphoserineCombined sources1 Publication1
Modified residuei41PhosphoserineCombined sources1 Publication1
Modified residuei45PhosphothreonineCombined sources1
Modified residuei52PhosphoserineCombined sources1 Publication1
Modified residuei58PhosphoserineCombined sources1
Modified residuei146PhosphoserineCombined sources1
Modified residuei147PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Dephosphorylated by calcineurin in a Ca2+ dependent manner (By similarity). Can be phosphorylated by DYRK2 (in vitro).By similarity1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y2V2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y2V2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y2V2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Y2V2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y2V2

PeptideAtlas

More...PeptideAtlasi		Q9Y2V2

PRoteomics IDEntifications database

More...PRIDEi		Q9Y2V2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		85909

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q9Y2V2

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9Y2V2, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y2V2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y2V2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000153048, Expressed in right testis and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y2V2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y2V2, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000153048, Tissue enhanced (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts with STYX (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		117124, 45 interactors

Protein interaction database and analysis system

More...IntActi		Q9Y2V2, 21 interactors

Molecular INTeraction database

More...MINTi		Q9Y2V2

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000379838

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y2V2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1147
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9Y2V2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y2V2

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini62 – 129CSDAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 52DisorderedSequence analysisAdd BLAST52

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3070, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000022

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_139526_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y2V2

Identification of Orthologs from Complete Genome Data

More...OMAi		THERWED

Database of Orthologous Groups

More...OrthoDBi		1560417at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y2V2

TreeFam database of animal gene trees

More...TreeFami		TF324381

Family and domain databases

Conserved Domains Database

More...CDDi		cd04458, CSP_CDS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.40.50.140, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011129, CSD
IPR019844, CSD_1
IPR002059, CSP_DNA-bd
IPR012340, NA-bd_OB-fold

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00313, CSD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00357, CSP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50249, SSF50249, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00352, CSD_1, 1 hit
PS51857, CSD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q9Y2V2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT 
        60         70         80         90        100
FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV 
       110        120        130        140 
PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS
Length:147
Mass (Da):15,892
Last modified:January 16, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i83D70DAE7B1FC573
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BNU9H3BNU9_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BUY4H3BUY4_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BSW7H3BSW7_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPY5H3BPY5_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L3X8I3L3X8_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTK3H3BTK3_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQY0H3BQY0_HUMAN
Calcium-regulated heat-stable prote...
CARHSP1
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti60G → V in AAD25021 (PubMed:9712905).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF115345 mRNA Translation: AAD25021.1
AK311777 mRNA Translation: BAG34720.1
CH471112 Genomic DNA Translation: EAW85196.1
CH471112 Genomic DNA Translation: EAW85197.1
CH471112 Genomic DNA Translation: EAW85198.1
CH471112 Genomic DNA Translation: EAW85199.1
BC003366 mRNA Translation: AAH03366.1
BC108283 mRNA Translation: AAI08284.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10537.1

NCBI Reference Sequences

More...RefSeqi		NP_001035941.1, NM_001042476.2
NP_001265189.1, NM_001278260.1
NP_001265190.1, NM_001278261.1
NP_001265191.1, NM_001278262.1
NP_001265192.1, NM_001278263.1
NP_001265193.1, NM_001278264.1
NP_001265194.1, NM_001278265.1
NP_001265195.1, NM_001278266.1
NP_055131.2, NM_014316.3
XP_005255286.1, XM_005255229.4
XP_011520746.1, XM_011522444.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000311052.10; ENSP00000311847.4; ENSG00000153048.11
ENST00000396593.6; ENSP00000379838.2; ENSG00000153048.11
ENST00000561530.5; ENSP00000455284.1; ENSG00000153048.11
ENST00000567554.5; ENSP00000455855.1; ENSG00000153048.11
ENST00000610831.4; ENSP00000478055.1; ENSG00000153048.11
ENST00000611932.4; ENSP00000481550.1; ENSG00000153048.11
ENST00000614449.4; ENSP00000480542.1; ENSG00000153048.11
ENST00000618335.4; ENSP00000483591.1; ENSG00000153048.11
ENST00000619881.4; ENSP00000480144.1; ENSG00000153048.11

Database of genes from NCBI RefSeq genomes

More...GeneIDi		23589

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:23589

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000311052.10; ENSP00000311847.4; NM_014316.4; NP_055131.2

UCSC genome browser

More...UCSCi		uc002czh.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF115345 mRNA Translation: AAD25021.1
AK311777 mRNA Translation: BAG34720.1
CH471112 Genomic DNA Translation: EAW85196.1
CH471112 Genomic DNA Translation: EAW85197.1
CH471112 Genomic DNA Translation: EAW85198.1
CH471112 Genomic DNA Translation: EAW85199.1
BC003366 mRNA Translation: AAH03366.1
BC108283 mRNA Translation: AAI08284.1
CCDSiCCDS10537.1
RefSeqiNP_001035941.1, NM_001042476.2
NP_001265189.1, NM_001278260.1
NP_001265190.1, NM_001278261.1
NP_001265191.1, NM_001278262.1
NP_001265192.1, NM_001278263.1
NP_001265193.1, NM_001278264.1
NP_001265194.1, NM_001278265.1
NP_001265195.1, NM_001278266.1
NP_055131.2, NM_014316.3
XP_005255286.1, XM_005255229.4
XP_011520746.1, XM_011522444.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3AQQX-ray2.80A/B/C/D1-147[»]
AlphaFoldDBiQ9Y2V2
SMRiQ9Y2V2
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi117124, 45 interactors
IntActiQ9Y2V2, 21 interactors
MINTiQ9Y2V2
STRINGi9606.ENSP00000379838

PTM databases

GlyGeniQ9Y2V2, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ9Y2V2
PhosphoSitePlusiQ9Y2V2

Genetic variation databases

BioMutaiCARHSP1
DMDMi41016932

Proteomic databases

EPDiQ9Y2V2
jPOSTiQ9Y2V2
MassIVEiQ9Y2V2
MaxQBiQ9Y2V2
PaxDbiQ9Y2V2
PeptideAtlasiQ9Y2V2
PRIDEiQ9Y2V2
ProteomicsDBi85909
TopDownProteomicsiQ9Y2V2

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		24559, 78 antibodies from 21 providers

The DNASU plasmid repository

More...DNASUi		23589

Genome annotation databases

EnsembliENST00000311052.10; ENSP00000311847.4; ENSG00000153048.11
ENST00000396593.6; ENSP00000379838.2; ENSG00000153048.11
ENST00000561530.5; ENSP00000455284.1; ENSG00000153048.11
ENST00000567554.5; ENSP00000455855.1; ENSG00000153048.11
ENST00000610831.4; ENSP00000478055.1; ENSG00000153048.11
ENST00000611932.4; ENSP00000481550.1; ENSG00000153048.11
ENST00000614449.4; ENSP00000480542.1; ENSG00000153048.11
ENST00000618335.4; ENSP00000483591.1; ENSG00000153048.11
ENST00000619881.4; ENSP00000480144.1; ENSG00000153048.11
GeneIDi23589
KEGGihsa:23589
MANE-SelectiENST00000311052.10; ENSP00000311847.4; NM_014316.4; NP_055131.2
UCSCiuc002czh.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23589
DisGeNETi23589

GeneCards: human genes, protein and diseases

More...GeneCardsi		CARHSP1
HGNCiHGNC:17150, CARHSP1
HPAiENSG00000153048, Tissue enhanced (testis)
MIMi616885, gene
neXtProtiNX_Q9Y2V2
OpenTargetsiENSG00000153048
PharmGKBiPA38440
VEuPathDBiHostDB:ENSG00000153048

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3070, Eukaryota
GeneTreeiENSGT00390000000022
HOGENOMiCLU_139526_1_0_1
InParanoidiQ9Y2V2
OMAiTHERWED
OrthoDBi1560417at2759
PhylomeDBiQ9Y2V2
TreeFamiTF324381

Enzyme and pathway databases

PathwayCommonsiQ9Y2V2
SignaLinkiQ9Y2V2
SIGNORiQ9Y2V2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		23589, 11 hits in 1096 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CARHSP1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CARHSP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		23589
PharosiQ9Y2V2, Tbio

Protein Ontology

More...PROi		PR:Q9Y2V2
RNActiQ9Y2V2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000153048, Expressed in right testis and 238 other tissues
ExpressionAtlasiQ9Y2V2, baseline and differential
GenevisibleiQ9Y2V2, HS

Family and domain databases

CDDicd04458, CSP_CDS, 1 hit
Gene3Di2.40.50.140, 1 hit
InterProiView protein in InterPro
IPR011129, CSD
IPR019844, CSD_1
IPR002059, CSP_DNA-bd
IPR012340, NA-bd_OB-fold
PfamiView protein in Pfam
PF00313, CSD, 1 hit
SMARTiView protein in SMART
SM00357, CSP, 1 hit
SUPFAMiSSF50249, SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00352, CSD_1, 1 hit
PS51857, CSD_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHSP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2V2
Secondary accession number(s): B2R4C3
, D3DUF5, Q2YDX5, Q9BQ53
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 16, 2004
Last modified: May 25, 2022
This is version 173 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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