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Entry version 151 (16 Oct 2019)
Sequence version 2 (18 May 2010)
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Protein

28S ribosomal protein S7, mitochondrial

Gene

MRPS7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
28S ribosomal protein S7, mitochondrial
Short name:
MRP-S7
Short name:
S7mt
Alternative name(s):
Mitochondrial small ribosomal subunit protein uS7m1 Publication
bMRP-27a
Short name:
bMRP27a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRPS7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14499 MRPS7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611974 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y2R9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Combined oxidative phosphorylation deficiency 34 (COXPD34)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive disorder caused by mitochondrial dysfunction and combined respiratory chain deficiencies of complexes I, III and IV. Clinical manifestations are variable and include congenital sensorineural deafness, lactic acidemia, and progressive hepatic and renal failure.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_080411184M → V in COXPD34; results in decreased mitochondrial protein synthesis and reduced levels of respiratory complexes; MRPS7 mRNA and protein levels are reduced. 1 PublicationCorresponds to variant dbSNP:rs115047866EnsemblClinVar.1

Keywords - Diseasei

Disease mutation, Primary mitochondrial disease

Organism-specific databases

DisGeNET

More...
DisGeNETi
51081

MalaCards human disease database

More...
MalaCardsi
MRPS7
MIMi617872 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000125445

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
457223 Syndromic sensorineural deafness due to combined oxidative phosphorylation defect

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31026

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y2R9

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MRPS7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296452884

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 37MitochondrionSequence analysisAdd BLAST37
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000027305638 – 24228S ribosomal protein S7, mitochondrialAdd BLAST205

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei208N6-acetyllysineCombined sources1
Modified residuei228N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y2R9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y2R9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y2R9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y2R9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y2R9

PeptideAtlas

More...
PeptideAtlasi
Q9Y2R9

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y2R9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85881

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q9Y2R9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y2R9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y2R9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9Y2R9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000125445 Expressed in 224 organ(s), highest expression level in muscle of leg

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y2R9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y2R9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA022522
HPA023007

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial small ribosomal subunit (mt-SSU), essential for mitochondrial protein synthesis (PubMed:25556185, PubMed:25838379). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins (PubMed:25838379).

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119271, 126 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9Y2R9

Protein interaction database and analysis system

More...
IntActi
Q9Y2R9, 60 interactors

Molecular INTeraction database

More...
MINTi
Q9Y2R9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000245539

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y2R9

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3291 Eukaryota
COG0049 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014620

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000039065

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y2R9

KEGG Orthology (KO)

More...
KOi
K02992

Identification of Orthologs from Complete Genome Data

More...
OMAi
PMISKFT

Database of Orthologous Groups

More...
OrthoDBi
1212658at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y2R9

TreeFam database of animal gene trees

More...
TreeFami
TF105978

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.455.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000235 Ribosomal_S5/S7
IPR023798 Ribosomal_S7_dom
IPR036823 Ribosomal_S7_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11205 PTHR11205, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00177 Ribosomal_S7, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002122 RPS7p_RPS7a_RPS5e_RPS7o, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47973 SSF47973, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q9Y2R9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPAVKVAR GWSGLALGVR RAVLQLPGLT QVRWSRYSPE FKDPLIDKEY
60 70 80 90 100
YRKPVEELTE EEKYVRELKK TQLIKAAPAG KTSSVFEDPV ISKFTNMMMI
110 120 130 140 150
GGNKVLARSL MIQTLEAVKR KQFEKYHAAS AEEQATIERN PYTIFHQALK
160 170 180 190 200
NCEPMIGLVP ILKGGRFYQV PVPLPDRRRR FLAMKWMITE CRDKKHQRTL
210 220 230 240
MPEKLSHKLL EAFHNQGPVI KRKHDLHKMA EANRALAHYR WW
Length:242
Mass (Da):28,134
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i945BC3E948B41CCA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QLS3J3QLS3_HUMAN
28S ribosomal protein S7, mitochond...
MRPS7
271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSI8J3KSI8_HUMAN
28S ribosomal protein S7, mitochond...
MRPS7
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKW2J3QKW2_HUMAN
28S ribosomal protein S7, mitochond...
MRPS7
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QQS1J3QQS1_HUMAN
28S ribosomal protein S7, mitochond...
MRPS7
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSV8J3KSV8_HUMAN
28S ribosomal protein S7, mitochond...
MRPS7
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti223K → S in BAD96715 (Ref. 3) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0300762A → V4 PublicationsCorresponds to variant dbSNP:rs8075276EnsemblClinVar.1
Natural variantiVAR_080411184M → V in COXPD34; results in decreased mitochondrial protein synthesis and reduced levels of respiratory complexes; MRPS7 mRNA and protein levels are reduced. 1 PublicationCorresponds to variant dbSNP:rs115047866EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF077042 mRNA Translation: AAD27775.1
AK222995 mRNA Translation: BAD96715.1
AK313854 mRNA Translation: BAG36582.1
AC022211 Genomic DNA No translation available.
BC000241 mRNA Translation: AAH00241.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11718.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7165

NCBI Reference Sequences

More...
RefSeqi
NP_057055.2, NM_015971.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000245539; ENSP00000245539; ENSG00000125445

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51081

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51081

UCSC genome browser

More...
UCSCi
uc002jnm.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF077042 mRNA Translation: AAD27775.1
AK222995 mRNA Translation: BAD96715.1
AK313854 mRNA Translation: BAG36582.1
AC022211 Genomic DNA No translation available.
BC000241 mRNA Translation: AAH00241.1
CCDSiCCDS11718.1
PIRiJC7165
RefSeqiNP_057055.2, NM_015971.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J9Melectron microscopy3.50AF1-242[»]
6NU2electron microscopy3.90AF35-242[»]
6NU3electron microscopy4.40AF1-242[»]
SMRiQ9Y2R9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi119271, 126 interactors
CORUMiQ9Y2R9
IntActiQ9Y2R9, 60 interactors
MINTiQ9Y2R9
STRINGi9606.ENSP00000245539

PTM databases

iPTMnetiQ9Y2R9
PhosphoSitePlusiQ9Y2R9
SwissPalmiQ9Y2R9

Polymorphism and mutation databases

BioMutaiMRPS7
DMDMi296452884

Proteomic databases

EPDiQ9Y2R9
jPOSTiQ9Y2R9
MassIVEiQ9Y2R9
MaxQBiQ9Y2R9
PaxDbiQ9Y2R9
PeptideAtlasiQ9Y2R9
PRIDEiQ9Y2R9
ProteomicsDBi85881
TopDownProteomicsiQ9Y2R9

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51081

Genome annotation databases

EnsembliENST00000245539; ENSP00000245539; ENSG00000125445
GeneIDi51081
KEGGihsa:51081
UCSCiuc002jnm.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51081
DisGeNETi51081

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MRPS7
HGNCiHGNC:14499 MRPS7
HPAiHPA022522
HPA023007
MalaCardsiMRPS7
MIMi611974 gene
617872 phenotype
neXtProtiNX_Q9Y2R9
OpenTargetsiENSG00000125445
Orphaneti457223 Syndromic sensorineural deafness due to combined oxidative phosphorylation defect
PharmGKBiPA31026

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3291 Eukaryota
COG0049 LUCA
GeneTreeiENSGT00390000014620
HOGENOMiHOG000039065
InParanoidiQ9Y2R9
KOiK02992
OMAiPMISKFT
OrthoDBi1212658at2759
PhylomeDBiQ9Y2R9
TreeFamiTF105978

Enzyme and pathway databases

ReactomeiR-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MRPS7 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
MRPS7

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51081
PharosiQ9Y2R9

Protein Ontology

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PROi
PR:Q9Y2R9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000125445 Expressed in 224 organ(s), highest expression level in muscle of leg
ExpressionAtlasiQ9Y2R9 baseline and differential
GenevisibleiQ9Y2R9 HS

Family and domain databases

Gene3Di1.10.455.10, 1 hit
InterProiView protein in InterPro
IPR000235 Ribosomal_S5/S7
IPR023798 Ribosomal_S7_dom
IPR036823 Ribosomal_S7_dom_sf
PANTHERiPTHR11205 PTHR11205, 1 hit
PfamiView protein in Pfam
PF00177 Ribosomal_S7, 1 hit
PIRSFiPIRSF002122 RPS7p_RPS7a_RPS5e_RPS7o, 1 hit
SUPFAMiSSF47973 SSF47973, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRT07_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2R9
Secondary accession number(s): B2R9N5, Q53GD6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 18, 2010
Last modified: October 16, 2019
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  7. Ribosomal proteins
    Ribosomal proteins families and list of entries
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