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UniProtKB - Q9Y2P4 (S27A6_HUMAN)

Entry version 138 (22 Apr 2020)
Sequence version 1 (01 Nov 1999)
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Protein

Long-chain fatty acid transport protein 6

Gene

SLC27A6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart (PubMed:12556534). Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs) (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi221 – 232AMPSequence analysisAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase
Biological processFatty acid metabolism, Lipid metabolism, Lipid transport, Transport
LigandNucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-804914 Transport of fatty acids

Protein family/group databases

Transport Classification Database

More...TCDBi		4.C.1.1.11 the fatty acid transporter (fat) family

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...SwissLipidsi		SLP:000001263

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Long-chain fatty acid transport protein 6
Short name:
FATP-6
Short name:
Fatty acid transport protein 6
Alternative name(s):
Arachidonate--CoA ligaseBy similarity (EC:6.2.1.15By similarity)
Fatty-acid-coenzyme A ligase, very long-chain 2By similarity (EC:6.2.1.-By similarity)
Solute carrier family 27 member 6
Very long-chain acyl-CoA synthetase homolog 1
Short name:
VLCSH1
Short name:
hVLCS-H1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC27A6
Synonyms:ACSVL2, FACVL2, FATP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:11000 SLC27A6

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		604196 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y2P4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		28965

Open Targets

More...OpenTargetsi		ENSG00000113396

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA35874

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y2P4 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLC27A6

Domain mapping of disease mutations (DMDM)

More...DMDMi		74725713

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001932161 – 619Long-chain fatty acid transport protein 6Add BLAST619

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9Y2P4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y2P4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y2P4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y2P4

PeptideAtlas

More...PeptideAtlasi		Q9Y2P4

PRoteomics IDEntifications database

More...PRIDEi		Q9Y2P4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		85853

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y2P4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y2P4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000113396 Expressed in heart and 117 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y2P4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y2P4 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000113396 Tissue enhanced (adrenal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		118790, 37 interactors

Protein interaction database and analysis system

More...IntActi		Q9Y2P4, 11 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000262462

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y2P4 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y2P4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1179 Eukaryota
ENOG410XQ8T LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159700

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000022_46_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y2P4

KEGG Orthology (KO)

More...KOi		K08749

Identification of Orthologs from Complete Genome Data

More...OMAi		VWRQFLD

Database of Orthologous Groups

More...OrthoDBi		386992at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y2P4

TreeFam database of animal gene trees

More...TreeFami		TF313430

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.12780, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf
IPR030309 FATP6

The PANTHER Classification System

More...PANTHERi		PTHR43107:SF10 PTHR43107:SF10, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00501 AMP-binding, 1 hit
PF13193 AMP-binding_C, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00455 AMP_BINDING, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y2P4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLSWLTVLG AGMVVLHFLQ KLLFPYFWDD FWFVLKVVLI IIRLKKYEKR 
        60         70         80         90        100
GELVTVLDKF LSHAKRQPRK PFIIYEGDIY TYQDVDKRSS RVAHVFLNHS 
       110        120        130        140        150
SLKKGDTVAL LMSNEPDFVH VWFGLAKLGC VVAFLNTNIR SNSLLNCIRA 
       160        170        180        190        200
CGPRALVVGA DLLGTVEEIL PSLSENISVW GMKDSVPQGV ISLKEKLSTS 
       210        220        230        240        250
PDEPVPRSHH VVSLLKSTCL YIFTSGTTGL PKAAVISQLQ VLRGSAVLWA 
       260        270        280        290        300
FGCTAHDIVY ITLPLYHSSA AILGISGCVE LGATCVLKKK FSASQFWSDC 
       310        320        330        340        350
KKYDVTVFQY IGELCRYLCK QSKREGEKDH KVRLAIGNGI RSDVWREFLD 
       360        370        380        390        400
RFGNIKVCEL YAATESSISF MNYTGRIGAI GRTNLFYKLL STFDLIKYDF 
       410        420        430        440        450
QKDEPMRNEQ GWCIHVKKGE PGLLISRVNA KNPFFGYAGP YKHTKDKLLC 
       460        470        480        490        500
DVFKKGDVYL NTGDLIVQDQ DNFLYFWDRT GDTFRWKGEN VATTEVADVI 
       510        520        530        540        550
GMLDFIQEAN VYGVAISGYE GRAGMASIIL KPNTSLDLEK VYEQVVTFLP 
       560        570        580        590        600
AYACPRFLRI QEKMEATGTF KLLKHQLVED GFNPLKISEP LYFMDNLKKS 
       610 
YVLLTRELYD QIMLGEIKL
Length:619
Mass (Da):70,112
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20264CE3FBB44FF5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RAJ2D6RAJ2_HUMAN
Long-chain fatty acid transport pro...
SLC27A6
162Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti25P → T in AAH41945 (PubMed:15489334).Curated1
Sequence conflicti207R → H in CAD97625 (PubMed:17974005).Curated1
Sequence conflicti215L → I in AAH41945 (PubMed:15489334).Curated1
Sequence conflicti231P → S in CAG33410 (Ref. 3) Curated1
Sequence conflicti432N → S in CAD97625 (PubMed:17974005).Curated1
Sequence conflicti596N → D in CAD97625 (PubMed:17974005).Curated1
Sequence conflicti618K → N in CAG33410 (Ref. 3) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04824519L → V1 PublicationCorresponds to variant dbSNP:rs2526247Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF064254 mRNA Translation: AAD29443.1
CR457129 mRNA Translation: CAG33410.1
BX537383 mRNA Translation: CAD97625.1
BC041945 mRNA Translation: AAH41945.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4145.1

NCBI Reference Sequences

More...RefSeqi		NP_001017372.1, NM_001017372.2
NP_001304913.1, NM_001317984.1
NP_054750.1, NM_014031.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000262462; ENSP00000262462; ENSG00000113396
ENST00000395266; ENSP00000378684; ENSG00000113396
ENST00000506176; ENSP00000421024; ENSG00000113396

Database of genes from NCBI RefSeq genomes

More...GeneIDi		28965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:28965

UCSC genome browser

More...UCSCi		uc003kuy.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF064254 mRNA Translation: AAD29443.1
CR457129 mRNA Translation: CAG33410.1
BX537383 mRNA Translation: CAD97625.1
BC041945 mRNA Translation: AAH41945.1
CCDSiCCDS4145.1
RefSeqiNP_001017372.1, NM_001017372.2
NP_001304913.1, NM_001317984.1
NP_054750.1, NM_014031.4

3D structure databases

SMRiQ9Y2P4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi118790, 37 interactors
IntActiQ9Y2P4, 11 interactors
STRINGi9606.ENSP00000262462

Chemistry databases

SwissLipidsiSLP:000001263

Protein family/group databases

TCDBi4.C.1.1.11 the fatty acid transporter (fat) family

PTM databases

iPTMnetiQ9Y2P4
PhosphoSitePlusiQ9Y2P4

Polymorphism and mutation databases

BioMutaiSLC27A6
DMDMi74725713

Proteomic databases

EPDiQ9Y2P4
jPOSTiQ9Y2P4
MassIVEiQ9Y2P4
PaxDbiQ9Y2P4
PeptideAtlasiQ9Y2P4
PRIDEiQ9Y2P4
ProteomicsDBi85853

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		1944 81 antibodies

Genome annotation databases

EnsembliENST00000262462; ENSP00000262462; ENSG00000113396
ENST00000395266; ENSP00000378684; ENSG00000113396
ENST00000506176; ENSP00000421024; ENSG00000113396
GeneIDi28965
KEGGihsa:28965
UCSCiuc003kuy.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		28965
DisGeNETi28965

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLC27A6
HGNCiHGNC:11000 SLC27A6
HPAiENSG00000113396 Tissue enhanced (adrenal)
MIMi604196 gene
neXtProtiNX_Q9Y2P4
OpenTargetsiENSG00000113396
PharmGKBiPA35874

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1179 Eukaryota
ENOG410XQ8T LUCA
GeneTreeiENSGT00940000159700
HOGENOMiCLU_000022_46_2_1
InParanoidiQ9Y2P4
KOiK08749
OMAiVWRQFLD
OrthoDBi386992at2759
PhylomeDBiQ9Y2P4
TreeFamiTF313430

Enzyme and pathway databases

ReactomeiR-HSA-804914 Transport of fatty acids

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLC27A6 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		SLC27A6

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		28965
PharosiQ9Y2P4 Tbio

Protein Ontology

More...PROi		PR:Q9Y2P4
RNActiQ9Y2P4 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000113396 Expressed in heart and 117 other tissues
ExpressionAtlasiQ9Y2P4 baseline and differential
GenevisibleiQ9Y2P4 HS

Family and domain databases

Gene3Di3.40.50.12780, 1 hit
InterProiView protein in InterPro
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf
IPR030309 FATP6
PANTHERiPTHR43107:SF10 PTHR43107:SF10, 1 hit
PfamiView protein in Pfam
PF00501 AMP-binding, 1 hit
PF13193 AMP-binding_C, 1 hit
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS27A6_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2P4
Secondary accession number(s): Q6IAM5, Q7Z6E6, Q86YF6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1999
Last modified: April 22, 2020
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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