Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 174 (12 Aug 2020)
Sequence version 1 (01 Nov 1999)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein 510

Gene

ZNF510

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri254 – 276C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri432 – 454C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri460 – 482C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri488 – 510C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri516 – 538C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri544 – 566C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri572 – 594C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri600 – 622C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 650C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9Y2H8

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 510
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF510
Synonyms:KIAA0972
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000081386.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29161, ZNF510

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y2H8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000081386

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134944603

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y2H8, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF510

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20178235

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476281 – 683Zinc finger protein 510Add BLAST683

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y2H8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y2H8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9Y2H8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y2H8

PeptideAtlas

More...
PeptideAtlasi
Q9Y2H8

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y2H8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85787

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y2H8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y2H8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000081386, Expressed in subventricular zone (outer) (primate) and 179 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y2H8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y2H8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000081386, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
116536, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y2H8, 23 interactors

Molecular INTeraction database

More...
MINTi
Q9Y2H8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364379

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y2H8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y2H8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini46 – 117KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri254 – 276C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri432 – 454C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri460 – 482C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri488 – 510C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri516 – 538C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri544 – 566C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri572 – 594C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri600 – 622C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 650C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153505

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_0_12_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y2H8

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
YEHNKNM

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y2H8

TreeFam database of animal gene trees

More...
TreeFami
TF337898

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 9 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y2H8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPHPEAITD CVTLNTVGQL AEGGYPLRFS TLFQEQQKMN ISQASVSFKD
60 70 80 90 100
VTIEFTQEEW QQMAPVQKNL YRDVMLENYS NLVSVGYCCF KPEVIFKLEQ
110 120 130 140 150
GEEPWFSEEE FSNQSHPKDY RGDDLIKQNK KIKDKHLEQA ICINNKTLTT
160 170 180 190 200
EEEKVLGKPF TLHVAAVAST KMSCKCNSWE VNLQSISEFI INNRNYSTKK
210 220 230 240 250
IGCGNVCENS PFKINFEKTQ TGEKFYEHNK NMKALNYNEN LPKHPKFQTL
260 270 280 290 300
EQAFECNKIG KAFNDKANCV KHNSSHTGET SSKDDEFRKN CDKKTLFDHR
310 320 330 340 350
RTGTGKKHLH LNQCGKSFEK STVEEYNKLN MGIKHYELNP SGNNFNRKAH
360 370 380 390 400
LTDPQTAVIE ENPLVSNDRT QTWVKSSEYH ENKKSYQTSV HRVRRRSHSM
410 420 430 440 450
MKPYKCNECG KSFCQKGHLI QHQRTHTGEK PFECSECGKT FSQKSHLSTH
460 470 480 490 500
QRIHTAEKPY KCNECGKTFV QKSTLRGHQR IHTGEKPYEC SECGKTFVQK
510 520 530 540 550
STLRDHHRIH TGEKSFQCNQ CGKTFGQKSN LRIHQRTHTG EKTYQCNECE
560 570 580 590 600
KSFWRKDHLI QHQKTHTGEK PFKCNECGKT FARTSTLRVH QRIHTGEKPF
610 620 630 640 650
KCNECGKKFV RKAILSDHQR IHTGEKPFQC NKCGKTFGQK SNLRIHQRTH
660 670 680
SGEKSYECNE YGKLCKKSTL SLYQKIQGEG NPY
Length:683
Mass (Da):79,142
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA87DB365993EE3F3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SZP4Q5SZP4_HUMAN
Zinc finger protein 510
ZNF510
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA76816 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01998243Q → R. Corresponds to variant dbSNP:rs2289651Ensembl.1
Natural variantiVAR_02189389C → R. Corresponds to variant dbSNP:rs3780548Ensembl.1
Natural variantiVAR_052848273N → K. Corresponds to variant dbSNP:rs10217154Ensembl.1
Natural variantiVAR_052849398H → D. Corresponds to variant dbSNP:rs11999094Ensembl.1
Natural variantiVAR_052850401M → I. Corresponds to variant dbSNP:rs10217494Ensembl.1
Natural variantiVAR_052851634G → E. Corresponds to variant dbSNP:rs10119874Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB023189 mRNA Translation: BAA76816.2 Different initiation.
AK292600 mRNA Translation: BAF85289.1
AL589843 Genomic DNA No translation available.
CH471174 Genomic DNA Translation: EAW92666.1
BC058022 mRNA Translation: AAH58022.1 Different termination.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35074.1

NCBI Reference Sequences

More...
RefSeqi
NP_001300988.1, NM_001314059.1
NP_055745.1, NM_014930.2
XP_016869972.1, XM_017014483.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000223428; ENSP00000223428; ENSG00000081386
ENST00000375231; ENSP00000364379; ENSG00000081386

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
22869

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:22869

UCSC genome browser

More...
UCSCi
uc004awn.1, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023189 mRNA Translation: BAA76816.2 Different initiation.
AK292600 mRNA Translation: BAF85289.1
AL589843 Genomic DNA No translation available.
CH471174 Genomic DNA Translation: EAW92666.1
BC058022 mRNA Translation: AAH58022.1 Different termination.
CCDSiCCDS35074.1
RefSeqiNP_001300988.1, NM_001314059.1
NP_055745.1, NM_014930.2
XP_016869972.1, XM_017014483.1

3D structure databases

SMRiQ9Y2H8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi116536, 3 interactors
IntActiQ9Y2H8, 23 interactors
MINTiQ9Y2H8
STRINGi9606.ENSP00000364379

PTM databases

iPTMnetiQ9Y2H8
PhosphoSitePlusiQ9Y2H8

Polymorphism and mutation databases

BioMutaiZNF510
DMDMi20178235

Proteomic databases

jPOSTiQ9Y2H8
MassIVEiQ9Y2H8
MaxQBiQ9Y2H8
PaxDbiQ9Y2H8
PeptideAtlasiQ9Y2H8
PRIDEiQ9Y2H8
ProteomicsDBi85787

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
55571, 79 antibodies

The DNASU plasmid repository

More...
DNASUi
22869

Genome annotation databases

EnsembliENST00000223428; ENSP00000223428; ENSG00000081386
ENST00000375231; ENSP00000364379; ENSG00000081386
GeneIDi22869
KEGGihsa:22869
UCSCiuc004awn.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
22869
EuPathDBiHostDB:ENSG00000081386.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF510
HGNCiHGNC:29161, ZNF510
HPAiENSG00000081386, Low tissue specificity
neXtProtiNX_Q9Y2H8
OpenTargetsiENSG00000081386
PharmGKBiPA134944603

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000153505
HOGENOMiCLU_002678_0_12_1
InParanoidiQ9Y2H8
KOiK09228
OMAiYEHNKNM
OrthoDBi1318335at2759
PhylomeDBiQ9Y2H8
TreeFamiTF337898

Enzyme and pathway databases

PathwayCommonsiQ9Y2H8
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
22869, 5 hits in 893 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF510, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
22869
PharosiQ9Y2H8, Tdark

Protein Ontology

More...
PROi
PR:Q9Y2H8
RNActiQ9Y2H8, protein

Gene expression databases

BgeeiENSG00000081386, Expressed in subventricular zone (outer) (primate) and 179 other tissues
ExpressionAtlasiQ9Y2H8, baseline and differential
GenevisibleiQ9Y2H8, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 9 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 10 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 9 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN510_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2H8
Secondary accession number(s): Q5SZP5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: November 1, 1999
Last modified: August 12, 2020
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again