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Entry version 134 (11 Dec 2019)
Sequence version 2 (28 Mar 2003)
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Protein

Disco-interacting protein 2 homolog C

Gene

DIP2C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Disco-interacting protein 2 homolog C
Short name:
DIP2 homolog C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DIP2C
Synonyms:KIAA0934
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000151240.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29150 DIP2C

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611380 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y2E4

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
22982

Open Targets

More...
OpenTargetsi
ENSG00000151240

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134961070

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y2E4 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DIP2C

Domain mapping of disease mutations (DMDM)

More...
DMDMi
29429225

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000507821 – 1556Disco-interacting protein 2 homolog CAdd BLAST1556

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei264PhosphothreonineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y2E4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y2E4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9Y2E4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y2E4

PeptideAtlas

More...
PeptideAtlasi
Q9Y2E4

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y2E4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
4789
85746 [Q9Y2E4-1]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q9Y2E4

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y2E4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y2E4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151240 Expressed in 244 organ(s), highest expression level in forebrain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y2E4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y2E4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA030264
HPA059325

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116631, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y2E4, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000280886

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y2E4 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y2E4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 119DMAP-interactionAdd BLAST111

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DIP2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3628 Eukaryota
COG0318 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182997

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000045270

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y2E4

Database of Orthologous Groups

More...
OrthoDBi
539697at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y2E4

TreeFam database of animal gene trees

More...
TreeFami
TF312871

Family and domain databases

Conserved Domains Database

More...
CDDi
cd05905 Dip2, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.12780, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf
IPR037337 Dip2-like_dom
IPR010506 DMAP1-bd

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501 AMP-binding, 2 hits
PF06464 DMAP_binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01137 DMAP_binding, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y2E4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADRSLEGMA LPLEVRARLA ELELELSEGD ITQKGYEKKR SKLIGAYLPQ
60 70 80 90 100
PPRVDQALPQ ERRAPVTPSS ASRYHRRRSS GSRDERYRSD VHTEAVQAAL
110 120 130 140 150
AKHKERKMAV PMPSKRRSLV VQTSMDAYTP PDTSSGSEDE GSVQGDSQGT
160 170 180 190 200
PTSSQGSINM EHWISQAIHG STTSTTSSSS TQSGGSGAAH RLADVMAQTH
210 220 230 240 250
IENHSAPPDV TTYTSEHSIQ VERPQGSTGS RTAPKYGNAE LMETGDGVPV
260 270 280 290 300
SSRVSAKIQQ LVNTLKRPKR PPLREFFVDD FEELLEVQQP DPNQPKPEGA
310 320 330 340 350
QMLAMRGEQL GVVTNWPPSL EAALQRWGTI SPKAPCLTTM DTNGKPLYIL
360 370 380 390 400
TYGKLWTRSM KVAYSILHKL GTKQEPMVRP GDRVALVFPN NDPAAFMAAF
410 420 430 440 450
YGCLLAEVVP VPIEVPLTRK DAGSQQIGFL LGSCGVTVAL TSDACHKGLP
460 470 480 490 500
KSPTGEIPQF KGWPKLLWFV TESKHLSKPP RDWFPHIKDA NNDTAYIEYK
510 520 530 540 550
TCKDGSVLGV TVTRTALLTH CQALTQACGY TEAETIVNVL DFKKDVGLWH
560 570 580 590 600
GILTSVMNMM HVISIPYSLM KVNPLSWIQK VCQYKAKVAC VKSRDMHWAL
610 620 630 640 650
VAHRDQRDIN LSSLRMLIVA DGANPWSISS CDAFLNVFQS KGLRQEVICP
660 670 680 690 700
CASSPEALTV AIRRPTDDSN QPPGRGVLSM HGLTYGVIRV DSEEKLSVLT
710 720 730 740 750
VQDVGLVMPG AIMCSVKPDG VPQLCRTDEI GELCVCAVAT GTSYYGLSGM
760 770 780 790 800
TKNTFEVFPM TSSGAPISEY PFIRTGLLGF VGPGGLVFVV GKMDGLMVVS
810 820 830 840 850
GRRHNADDIV ATALAVEPMK FVYRGRIAVF SVTVLHDERI VIVAEQRPDS
860 870 880 890 900
TEEDSFQWMS RVLQAIDSIH QVGVYCLALV PANTLPKTPL GGIHLSETKQ
910 920 930 940 950
LFLEGSLHPC NVLMCPHTCV TNLPKPRQKQ PEIGPASVMV GNLVSGKRIA
960 970 980 990 1000
QASGRDLGQI EDNDQARKFL FLSEVLQWRA QTTPDHILYT LLNCRGAIAN
1010 1020 1030 1040 1050
SLTCVQLHKR AEKIAVMLME RGHLQDGDHV ALVYPPGIDL IAAFYGCLYA
1060 1070 1080 1090 1100
GCVPITVRPP HPQNIATTLP TVKMIVEVSR SACLMTTQLI CKLLRSREAA
1110 1120 1130 1140 1150
AAVDVRTWPL ILDTDDLPKK RPAQICKPCN PDTLAYLDFS VSTTGMLAGV
1160 1170 1180 1190 1200
KMSHAATSAF CRSIKLQCEL YPSREVAICL DPYCGLGFVL WCLCSVYSGH
1210 1220 1230 1240 1250
QSILIPPSEL ETNPALWLLA VSQYKVRDTF CSYSVMELCT KGLGSQTESL
1260 1270 1280 1290 1300
KARGLDLSRV RTCVVVAEER PRIALTQSFS KLFKDLGLHP RAVSTSFGCR
1310 1320 1330 1340 1350
VNLAICLQGT SGPDPTTVYV DMRALRHDRV RLVERGSPHS LPLMESGKIL
1360 1370 1380 1390 1400
PGVRIIIANP ETKGPLGDSH LGEIWVHSAH NASGYFTIYG DESLQSDHFN
1410 1420 1430 1440 1450
SRLSFGDTQT IWARTGYLGF LRRTELTDAN GERHDALYVV GALDEAMELR
1460 1470 1480 1490 1500
GMRYHPIDIE TSVIRAHKSV TECAVFTWTN LLVVVVELDG SEQEALDLVP
1510 1520 1530 1540 1550
LVTNVVLEEH YLIVGVVVVV DIGVIPINSR GEKQRMHLRD GFLADQLDPI

YVAYNM
Length:1,556
Mass (Da):170,767
Last modified:March 28, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4CA7F0719C384EA
GO
Isoform 2 (identifier: Q9Y2E4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-679: Missing.
     996-1050: GAIANSLTCV...IAAFYGCLYA → VRRGAGLPWL...TETFVPRDCF
     1051-1556: Missing.

Show »
Length:371
Mass (Da):40,613
Checksum:i9F62E018E8DCFC50
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0U1RQW6A0A0U1RQW6_HUMAN
Disco-interacting protein 2 homolog...
DIP2C
1,622Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EPU2E7EPU2_HUMAN
Disco-interacting protein 2 homolog...
DIP2C
1,537Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y5A8H0Y5A8_HUMAN
Disco-interacting protein 2 homolog...
DIP2C
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y7Q3H0Y7Q3_HUMAN
Disco-interacting protein 2 homolog...
DIP2C
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA76778 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035905586A → E in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_035906622G → S in a colorectal cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs771008735Ensembl.1
Natural variantiVAR_0359071264V → M in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs929297365Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0568981 – 679Missing in isoform 2. 1 PublicationAdd BLAST679
Alternative sequenceiVSP_056899996 – 1050GAIAN…GCLYA → VRRGAGLPWLLASRGLAWFL GALLLLSLNPFASVLWEFFL CFAILTETFVPRDCF in isoform 2. 1 PublicationAdd BLAST55
Alternative sequenceiVSP_0569001051 – 1556Missing in isoform 2. 1 PublicationAdd BLAST506

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB023151 mRNA Translation: BAA76778.2 Different initiation.
AK298353 mRNA Translation: BAG60597.1
AL358216 Genomic DNA No translation available.
AL157709 Genomic DNA No translation available.
AL359957 Genomic DNA No translation available.
AL603831 Genomic DNA No translation available.
AL669841 Genomic DNA No translation available.
BC063313 mRNA Translation: AAH63313.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7054.1 [Q9Y2E4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_055789.1, NM_014974.2 [Q9Y2E4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000280886; ENSP00000280886; ENSG00000151240 [Q9Y2E4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
22982

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:22982

UCSC genome browser

More...
UCSCi
uc001ifp.4 human [Q9Y2E4-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023151 mRNA Translation: BAA76778.2 Different initiation.
AK298353 mRNA Translation: BAG60597.1
AL358216 Genomic DNA No translation available.
AL157709 Genomic DNA No translation available.
AL359957 Genomic DNA No translation available.
AL603831 Genomic DNA No translation available.
AL669841 Genomic DNA No translation available.
BC063313 mRNA Translation: AAH63313.1
CCDSiCCDS7054.1 [Q9Y2E4-1]
RefSeqiNP_055789.1, NM_014974.2 [Q9Y2E4-1]

3D structure databases

SMRiQ9Y2E4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi116631, 4 interactors
IntActiQ9Y2E4, 1 interactor
STRINGi9606.ENSP00000280886

PTM databases

CarbonylDBiQ9Y2E4
iPTMnetiQ9Y2E4
PhosphoSitePlusiQ9Y2E4

Polymorphism and mutation databases

BioMutaiDIP2C
DMDMi29429225

Proteomic databases

EPDiQ9Y2E4
jPOSTiQ9Y2E4
MassIVEiQ9Y2E4
PaxDbiQ9Y2E4
PeptideAtlasiQ9Y2E4
PRIDEiQ9Y2E4
ProteomicsDBi4789
85746 [Q9Y2E4-1]

Genome annotation databases

EnsembliENST00000280886; ENSP00000280886; ENSG00000151240 [Q9Y2E4-1]
GeneIDi22982
KEGGihsa:22982
UCSCiuc001ifp.4 human [Q9Y2E4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
22982
DisGeNETi22982
EuPathDBiHostDB:ENSG00000151240.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DIP2C
HGNCiHGNC:29150 DIP2C
HPAiHPA030264
HPA059325
MIMi611380 gene
neXtProtiNX_Q9Y2E4
OpenTargetsiENSG00000151240
PharmGKBiPA134961070

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3628 Eukaryota
COG0318 LUCA
GeneTreeiENSGT00950000182997
HOGENOMiHOG000045270
InParanoidiQ9Y2E4
OrthoDBi539697at2759
PhylomeDBiQ9Y2E4
TreeFamiTF312871

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
DIP2C human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
22982
PharosiQ9Y2E4 Tbio

Protein Ontology

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PROi
PR:Q9Y2E4
RNActiQ9Y2E4 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000151240 Expressed in 244 organ(s), highest expression level in forebrain
ExpressionAtlasiQ9Y2E4 baseline and differential
GenevisibleiQ9Y2E4 HS

Family and domain databases

CDDicd05905 Dip2, 2 hits
Gene3Di3.40.50.12780, 2 hits
InterProiView protein in InterPro
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf
IPR037337 Dip2-like_dom
IPR010506 DMAP1-bd
PfamiView protein in Pfam
PF00501 AMP-binding, 2 hits
PF06464 DMAP_binding, 1 hit
SMARTiView protein in SMART
SM01137 DMAP_binding, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDIP2C_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y2E4
Secondary accession number(s): B4DPI5, Q5SS78
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: March 28, 2003
Last modified: December 11, 2019
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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