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Entry version 135 (11 Dec 2019)
Sequence version 4 (30 Nov 2010)
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Protein

Solute carrier family 22 member 14

Gene

SLC22A14

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.1.19.22 the major facilitator superfamily (mfs)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 22 member 14
Alternative name(s):
Organic cation transporter-like 4
Short name:
ORCTL-4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC22A14
Synonyms:OCTL2, ORCTL4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000144671.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:8495 SLC22A14

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604048 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y267

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 70CytoplasmicSequence analysisAdd BLAST70
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 184ExtracellularSequence analysisAdd BLAST93
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Topological domaini206 – 210CytoplasmicSequence analysis5
Transmembranei211 – 231HelicalSequence analysisAdd BLAST21
Topological domaini232 – 235ExtracellularSequence analysis4
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Topological domaini257 – 270CytoplasmicSequence analysisAdd BLAST14
Transmembranei271 – 291HelicalSequence analysisAdd BLAST21
Topological domaini292 – 297ExtracellularSequence analysis6
Transmembranei298 – 318HelicalSequence analysisAdd BLAST21
Topological domaini319 – 379CytoplasmicSequence analysisAdd BLAST61
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Topological domaini401 – 408ExtracellularSequence analysis8
Transmembranei409 – 431HelicalSequence analysisAdd BLAST23
Topological domaini432 – 437CytoplasmicSequence analysis6
Transmembranei438 – 458HelicalSequence analysisAdd BLAST21
Topological domaini459 – 488ExtracellularSequence analysisAdd BLAST30
Transmembranei489 – 509HelicalSequence analysisAdd BLAST21
Topological domaini510 – 512CytoplasmicSequence analysis3
Transmembranei513 – 533HelicalSequence analysisAdd BLAST21
Topological domaini534 – 538ExtracellularSequence analysis5
Transmembranei539 – 559HelicalSequence analysisAdd BLAST21
Topological domaini560 – 594CytoplasmicSequence analysisAdd BLAST35

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000144671

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA32815

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9Y267 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC22A14

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104317

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002307841 – 594Solute carrier family 22 member 14Add BLAST594

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi99N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi117N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi125N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi150N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y267

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y267

PeptideAtlas

More...
PeptideAtlasi
Q9Y267

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y267

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85672

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y267

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y267

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000144671 Expressed in 138 organ(s), highest expression level in male germ cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y267 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y267 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9Y267, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000273173

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9Y267 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IRHZ Eukaryota
ENOG410XQIT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162395

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234569

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y267

KEGG Orthology (KO)

More...
KOi
K08210

Identification of Orthologs from Complete Genome Data

More...
OMAi
LVMSCVW

Database of Orthologous Groups

More...
OrthoDBi
704438at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y267

TreeFam database of animal gene trees

More...
TreeFami
TF315847

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083 Sugar_tr, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9Y267-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGEENFKEE LRSQDASRNL NQHEVAGHPH SWSLEMLLRR LRAVHTKQDD
60 70 80 90 100
KFANLLDAVG EFGTFQQRLV ALTFIPSIMS AFFMFADHFV FTAQKPYCNT
110 120 130 140 150
SWILAVGPHL SKAEQLNLTI PQAPNGSFLT CFMYLPVPWN LDSIIQFGLN
160 170 180 190 200
DTDTCQDGWI YPDAKKRSLI NEFDLVCGME TKKDTAQIMF MAGLPIGSLI
210 220 230 240 250
FRLITDKMGR YPAILLSLLG LIIFGFGTAF MNSFHLYLFF RFGISQSVVG
260 270 280 290 300
YAISSISLAT EWLVGEHRAH AIILGHCFFA VGAVLLTGIA YSLPHWQLLF
310 320 330 340 350
LVGGILVIPF ISYIWILPES PRWLMMKGKV KEAKQVLCYA ASVNKKTIPS
360 370 380 390 400
NLLDELQLPR KKVTRASVLD FCKNRQLCKV TLVMSCVWFT VSYTYFTLSL
410 420 430 440 450
RMRELGVSVH FRHVVPSIME VPARLCCIFL LQQIGRKWSL AVTLLQAIIW
460 470 480 490 500
CLLLLFLPEG EDGLRLKWPR CPATELKSMT ILVLMLREFS LAATVTVFFL
510 520 530 540 550
YTAELLPTVL RATGLGLVSL ASVAGAILSL TIISQTPSLL PIFLCCVLAI
560 570 580 590
VAFSLSSLLP ETRDQPLSES LNHSSQIRNK VKDMKTKETS SDDV
Length:594
Mass (Da):66,684
Last modified:November 30, 2010 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7EA290B06222B681
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H7H1F5H7H1_HUMAN
Solute carrier family 22 member 14
SLC22A14
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti282G → W in BAA76351 (PubMed:10072596).Curated1
Sequence conflicti282G → W in BAA77626 (PubMed:10231028).Curated1
Sequence conflicti470R → H in BAG37720 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_055108108P → H. Corresponds to variant dbSNP:rs9847584Ensembl.1
Natural variantiVAR_055109112K → E. Corresponds to variant dbSNP:rs2073714Ensembl.1
Natural variantiVAR_055110144I → T2 PublicationsCorresponds to variant dbSNP:rs194685Ensembl.1
Natural variantiVAR_055111245S → L. Corresponds to variant dbSNP:rs1078846Ensembl.1
Natural variantiVAR_055112284V → M5 PublicationsCorresponds to variant dbSNP:rs818818Ensembl.1
Natural variantiVAR_055113292S → G5 PublicationsCorresponds to variant dbSNP:rs818817Ensembl.1
Natural variantiVAR_055114466L → P. Corresponds to variant dbSNP:rs34256819Ensembl.1
Natural variantiVAR_055115512A → V. Corresponds to variant dbSNP:rs2070492Ensembl.1
Natural variantiVAR_055116560P → R2 PublicationsCorresponds to variant dbSNP:rs240033Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB011082 mRNA Translation: BAA76351.1
AB026898 Genomic DNA Translation: BAA77626.1
AK315317 mRNA Translation: BAG37720.1
AP006193 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64529.1
BC075070 mRNA Translation: AAH75070.1
BC075071 mRNA Translation: AAH75071.1
BC126482 mRNA Translation: AAI26483.1
BC130543 mRNA Translation: AAI30544.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2677.1

NCBI Reference Sequences

More...
RefSeqi
NP_001306962.1, NM_001320033.1
NP_004794.2, NM_004803.4
XP_005265642.1, XM_005265585.4
XP_011532547.1, XM_011534245.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000273173; ENSP00000273173; ENSG00000144671
ENST00000448498; ENSP00000396283; ENSG00000144671

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9389

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9389

UCSC genome browser

More...
UCSCi
uc003cib.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011082 mRNA Translation: BAA76351.1
AB026898 Genomic DNA Translation: BAA77626.1
AK315317 mRNA Translation: BAG37720.1
AP006193 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64529.1
BC075070 mRNA Translation: AAH75070.1
BC075071 mRNA Translation: AAH75071.1
BC126482 mRNA Translation: AAI26483.1
BC130543 mRNA Translation: AAI30544.1
CCDSiCCDS2677.1
RefSeqiNP_001306962.1, NM_001320033.1
NP_004794.2, NM_004803.4
XP_005265642.1, XM_005265585.4
XP_011532547.1, XM_011534245.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9Y267, 2 interactors
STRINGi9606.ENSP00000273173

Protein family/group databases

TCDBi2.A.1.19.22 the major facilitator superfamily (mfs)

PTM databases

iPTMnetiQ9Y267
PhosphoSitePlusiQ9Y267

Polymorphism and mutation databases

BioMutaiSLC22A14
DMDMi313104317

Proteomic databases

jPOSTiQ9Y267
PaxDbiQ9Y267
PeptideAtlasiQ9Y267
PRIDEiQ9Y267
ProteomicsDBi85672

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9389

Genome annotation databases

EnsembliENST00000273173; ENSP00000273173; ENSG00000144671
ENST00000448498; ENSP00000396283; ENSG00000144671
GeneIDi9389
KEGGihsa:9389
UCSCiuc003cib.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9389
EuPathDBiHostDB:ENSG00000144671.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC22A14
HGNCiHGNC:8495 SLC22A14
MIMi604048 gene
neXtProtiNX_Q9Y267
OpenTargetsiENSG00000144671
PharmGKBiPA32815

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IRHZ Eukaryota
ENOG410XQIT LUCA
GeneTreeiENSGT00940000162395
HOGENOMiHOG000234569
InParanoidiQ9Y267
KOiK08210
OMAiLVMSCVW
OrthoDBi704438at2759
PhylomeDBiQ9Y267
TreeFamiTF315847

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9389
PharosiQ9Y267 Tdark

Protein Ontology

More...
PROi
PR:Q9Y267
RNActiQ9Y267 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000144671 Expressed in 138 organ(s), highest expression level in male germ cell
ExpressionAtlasiQ9Y267 baseline and differential
GenevisibleiQ9Y267 HS

Family and domain databases

InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS22AE_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y267
Secondary accession number(s): A0AVS9
, A1L4H6, B2RCX3, Q6DJT3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 30, 2010
Last modified: December 11, 2019
This is version 135 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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