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UniProtKB - Q9Y242 (TCF19_HUMAN)

Entry version 167 (02 Dec 2020)
Sequence version 2 (20 Feb 2007)
Previous versions | rss
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Protein

Transcription factor 19

Gene

TCF19

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri296 – 339PHD-typeAdd BLAST44

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9Y242

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription factor 19
Short name:
TCF-19
Alternative name(s):
Transcription factor SC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TCF19
Synonyms:SC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000137310.11

Human Gene Nomenclature Database

More...HGNCi		HGNC:11629, TCF19

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		600912, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9Y242

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		6941

Open Targets

More...OpenTargetsi		ENSG00000137310

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA36384

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9Y242, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TCF19

Domain mapping of disease mutations (DMDM)

More...DMDMi		126302606

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000593271 – 345Transcription factor 19Add BLAST345

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei78PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9Y242

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9Y242

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9Y242

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9Y242

PeptideAtlas

More...PeptideAtlasi		Q9Y242

PRoteomics IDEntifications database

More...PRIDEi		Q9Y242

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		85640

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9Y242

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9Y242

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Growth regulated.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000137310, Expressed in ventricular zone and 153 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9Y242, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9Y242, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000137310, Tissue enhanced (lymphoid)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		112801, 29 interactors

Protein interaction database and analysis system

More...IntActi		Q9Y242, 24 interactors

Molecular INTeraction database

More...MINTi		Q9Y242

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000365433

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9Y242, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9Y242

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini31 – 88FHAPROSITE-ProRule annotationAdd BLAST58

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi187 – 300Pro-richAdd BLAST114

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri296 – 339PHD-typeAdd BLAST44

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RHCY, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000015391

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_041089_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9Y242

Identification of Orthologs from Complete Genome Data

More...OMAi		SGAGCTY

Database of Orthologous Groups

More...OrthoDBi		1106192at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9Y242

TreeFam database of animal gene trees

More...TreeFami		TF334697

Family and domain databases

Conserved Domains Database

More...CDDi		cd00060, FHA, 1 hit
cd15609, PHD_TCF19, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000253, FHA_dom
IPR008984, SMAD_FHA_dom_sf
IPR042803, TCF19
IPR039095, TCF19_PHD
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR013083, Znf_RING/FYVE/PHD

The PANTHER Classification System

More...PANTHERi		PTHR15464, PTHR15464, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00498, FHA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00240, FHA, 1 hit
SM00249, PHD, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49879, SSF49879, 1 hit
SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50006, FHA_DOMAIN, 1 hit
PS01359, ZF_PHD_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9Y242-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP 
        60         70         80         90        100
GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD 
       110        120        130        140        150
LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR 
       160        170        180        190        200
PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK 
       210        220        230        240        250
SLPVPAPPGE MGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME 
       260        270        280        290        300
PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE PCAAPCCCLP 
       310        320        330        340 
QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT
Length:345
Mass (Da):37,184
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB5730936A842B83A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D2IYK5D2IYK5_HUMAN
TCF19
TCF19 hCG_25998
345Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JIJ7A0A0G2JIJ7_HUMAN
TCF19
TCF19
345Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YFN0H0YFN0_HUMAN
Transcription factor 19
TCF19
217Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB60363 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27A → V in AAB60363 (Ref. 3) Curated1
Sequence conflicti123Q → N in AAB19475 (PubMed:1868030).Curated1
Sequence conflicti193S → T in AAB19475 (PubMed:1868030).Curated1
Sequence conflicti268R → A in AAB60363 (Ref. 3) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051604109P → S1 PublicationCorresponds to variant dbSNP:rs7750641Ensembl.1
Natural variantiVAR_017741211M → V8 PublicationsCorresponds to variant dbSNP:rs2073721Ensembl.1
Natural variantiVAR_017742241P → L3 PublicationsCorresponds to variant dbSNP:rs2073724Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
S53374 mRNA Translation: AAB19475.2 Frameshift.
AB029516 Genomic DNA Translation: BAA82324.1
AB029517 Genomic DNA Translation: BAA82325.1
AB029518 Genomic DNA Translation: BAA82326.1
AB029519 Genomic DNA Translation: BAA82327.1
U25826 Genomic DNA Translation: AAB60363.1 Frameshift.
BA000025 Genomic DNA Translation: BAB63312.1
AB088113 Genomic DNA Translation: BAC54945.1
AB103619 Genomic DNA Translation: BAF31280.1
AB202105 Genomic DNA Translation: BAE78629.1
BT007247 mRNA Translation: AAP35911.1
AL662833 Genomic DNA No translation available.
AL662844 Genomic DNA No translation available.
AL773544 Genomic DNA No translation available.
BX088580 Genomic DNA No translation available.
CR759815 Genomic DNA No translation available.
CR388229 Genomic DNA No translation available.
CR753819 Genomic DNA No translation available.
CR847794 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03363.1
BC002493 mRNA Translation: AAH02493.1
BC033086 mRNA Translation: AAH33086.1
BC044632 mRNA Translation: AAH44632.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS43446.1

Protein sequence database of the Protein Information Resource

More...PIRi		A61188

NCBI Reference Sequences

More...RefSeqi		NP_001070979.1, NM_001077511.1
NP_001305837.1, NM_001318908.1
NP_009040.2, NM_007109.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000376255; ENSP00000365431; ENSG00000137310
ENST00000376257; ENSP00000365433; ENSG00000137310

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6941

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:6941

UCSC genome browser

More...UCSCi		uc003nss.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S53374 mRNA Translation: AAB19475.2 Frameshift.
AB029516 Genomic DNA Translation: BAA82324.1
AB029517 Genomic DNA Translation: BAA82325.1
AB029518 Genomic DNA Translation: BAA82326.1
AB029519 Genomic DNA Translation: BAA82327.1
U25826 Genomic DNA Translation: AAB60363.1 Frameshift.
BA000025 Genomic DNA Translation: BAB63312.1
AB088113 Genomic DNA Translation: BAC54945.1
AB103619 Genomic DNA Translation: BAF31280.1
AB202105 Genomic DNA Translation: BAE78629.1
BT007247 mRNA Translation: AAP35911.1
AL662833 Genomic DNA No translation available.
AL662844 Genomic DNA No translation available.
AL773544 Genomic DNA No translation available.
BX088580 Genomic DNA No translation available.
CR759815 Genomic DNA No translation available.
CR388229 Genomic DNA No translation available.
CR753819 Genomic DNA No translation available.
CR847794 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03363.1
BC002493 mRNA Translation: AAH02493.1
BC033086 mRNA Translation: AAH33086.1
BC044632 mRNA Translation: AAH44632.1
CCDSiCCDS43446.1
PIRiA61188
RefSeqiNP_001070979.1, NM_001077511.1
NP_001305837.1, NM_001318908.1
NP_009040.2, NM_007109.2

3D structure databases

SMRiQ9Y242
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi112801, 29 interactors
IntActiQ9Y242, 24 interactors
MINTiQ9Y242
STRINGi9606.ENSP00000365433

PTM databases

iPTMnetiQ9Y242
PhosphoSitePlusiQ9Y242

Polymorphism and mutation databases

BioMutaiTCF19
DMDMi126302606

Proteomic databases

jPOSTiQ9Y242
MassIVEiQ9Y242
MaxQBiQ9Y242
PaxDbiQ9Y242
PeptideAtlasiQ9Y242
PRIDEiQ9Y242
ProteomicsDBi85640

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26851, 212 antibodies

The DNASU plasmid repository

More...DNASUi		6941

Genome annotation databases

EnsembliENST00000376255; ENSP00000365431; ENSG00000137310
ENST00000376257; ENSP00000365433; ENSG00000137310
GeneIDi6941
KEGGihsa:6941
UCSCiuc003nss.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6941
DisGeNETi6941
EuPathDBiHostDB:ENSG00000137310.11

GeneCards: human genes, protein and diseases

More...GeneCardsi		TCF19
HGNCiHGNC:11629, TCF19
HPAiENSG00000137310, Tissue enhanced (lymphoid)
MIMi600912, gene
neXtProtiNX_Q9Y242
OpenTargetsiENSG00000137310
PharmGKBiPA36384

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RHCY, Eukaryota
GeneTreeiENSGT00390000015391
HOGENOMiCLU_041089_0_0_1
InParanoidiQ9Y242
OMAiSGAGCTY
OrthoDBi1106192at2759
PhylomeDBiQ9Y242
TreeFamiTF334697

Enzyme and pathway databases

PathwayCommonsiQ9Y242

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		6941, 2 hits in 850 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TCF19, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		TCF19

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		6941
PharosiQ9Y242, Tbio

Protein Ontology

More...PROi		PR:Q9Y242
RNActiQ9Y242, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000137310, Expressed in ventricular zone and 153 other tissues
ExpressionAtlasiQ9Y242, baseline and differential
GenevisibleiQ9Y242, HS

Family and domain databases

CDDicd00060, FHA, 1 hit
cd15609, PHD_TCF19, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000253, FHA_dom
IPR008984, SMAD_FHA_dom_sf
IPR042803, TCF19
IPR039095, TCF19_PHD
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR013083, Znf_RING/FYVE/PHD
PANTHERiPTHR15464, PTHR15464, 2 hits
PfamiView protein in Pfam
PF00498, FHA, 1 hit
SMARTiView protein in SMART
SM00240, FHA, 1 hit
SM00249, PHD, 1 hit
SUPFAMiSSF49879, SSF49879, 1 hit
SSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50006, FHA_DOMAIN, 1 hit
PS01359, ZF_PHD_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTCF19_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y242
Secondary accession number(s): A6NCT8
, B0UY11, Q0EFA8, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: February 20, 2007
Last modified: December 2, 2020
This is version 167 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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